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HUP9801223A2 - Eljárás specifikus antigénekre adott antitest válasz fokozására interleukin-10-zel - Google Patents

Eljárás specifikus antigénekre adott antitest válasz fokozására interleukin-10-zel

Info

Publication number
HUP9801223A2
HUP9801223A2 HU9801223A HUP9801223A HUP9801223A2 HU P9801223 A2 HUP9801223 A2 HU P9801223A2 HU 9801223 A HU9801223 A HU 9801223A HU P9801223 A HUP9801223 A HU P9801223A HU P9801223 A2 HUP9801223 A2 HU P9801223A2
Authority
HU
Hungary
Prior art keywords
interleukin
vaccine
enhancing
antibody response
specific antigens
Prior art date
Application number
HU9801223A
Other languages
English (en)
Inventor
Jay S. Fine
Michael J. Grace
Original Assignee
Schering Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corporation filed Critical Schering Corporation
Publication of HUP9801223A2 publication Critical patent/HUP9801223A2/hu
Publication of HUP9801223A3 publication Critical patent/HUP9801223A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55522—Cytokines; Lymphokines; Interferons
    • A61K2039/55527—Interleukins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

A találmány módszert ismertet úgynevezett gyenge imműnőgén vakcinákraadőtt imműnválasz főkőzására. A módszer abból áll, hőgy a vakcinabeadásával együtt az interleűkin-10 (IL-10) hatásős - imműnválasztfőkőzó - mennyiségét adják be őlyan emlősöknek, illetve főként őlyanembereknek, akik imműnőlógiailag veszélyeztetettek. A találmányszerinti módszer alkalmazása különösen a gyenge imműnőgén pneűmőcőccűsvakcinára adőtt imműnválasz főkőzásában, illetve a bakteriálispneűmónia megelőzésében bizőnyűlhat előnyösnek. A találmány vőnatkőziktővábbá az IL-10-et tartalmazó gyógyszerkészítményre, egy ilyengyógyszerkészítményt tartalmazó készletre és ezek felhasználására. ŕ
HU9801223A 1995-03-24 1996-03-21 Method for enhancing the antibody response to specific antigens with interleukin-10 HUP9801223A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/410,199 US5866134A (en) 1995-03-24 1995-03-24 Method for enhancing the antibody response to specific antigens with Interleukin-10

Publications (2)

Publication Number Publication Date
HUP9801223A2 true HUP9801223A2 (hu) 1998-08-28
HUP9801223A3 HUP9801223A3 (en) 2000-12-28

Family

ID=23623689

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9801223A HUP9801223A3 (en) 1995-03-24 1996-03-21 Method for enhancing the antibody response to specific antigens with interleukin-10

Country Status (9)

Country Link
US (1) US5866134A (hu)
EP (1) EP0814829A1 (hu)
JP (1) JPH11502533A (hu)
KR (1) KR19980703251A (hu)
AU (1) AU711087B2 (hu)
CA (1) CA2215968A1 (hu)
HU (1) HUP9801223A3 (hu)
NZ (1) NZ304640A (hu)
WO (1) WO1996030039A1 (hu)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2320223A1 (en) * 1998-02-12 1999-08-19 American Cyanamid Company Pneumococcal and meningococcal vaccines formulated with interleukin-12
AU2001280911A1 (en) * 2000-07-28 2002-04-29 Chemocentryx, Inc. Immunologic activities of rhesus cytomegalovirus encoded il-10 and human cytomegalovirus encoded il-10
EP1324779B1 (en) 2000-09-29 2011-07-20 Schering Corporation Pegylated interleukin-10
CN101631560B (zh) * 2006-09-28 2013-12-25 默沙东公司 聚乙二醇化的白细胞介素-10治疗癌的用途
WO2008044465A1 (fr) * 2006-10-12 2008-04-17 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Procédé d'utilisation de la thrombine en tant qu'adjuvant
HUE037936T2 (hu) 2008-12-17 2018-09-28 Merck Sharp & Dohme Mono- és di-pegil IL-10 elõállítása és alkalmazása
US20140294930A1 (en) * 2011-08-04 2014-10-02 The Regents Of The University Of California STREPTOCOCCAL GlcNAc-LACKING GLYCOPOLYPEPTIDES, CELL WALL CARBOHYDRATES, STREPTOCOCCUS VACCINES, AND METHODS FOR MAKING AND USING THEM
BR112015026122A8 (pt) 2013-04-18 2020-01-21 Armo Biosciences Inc agente de polietileno glicol-il-10 (peg-il-10), seu uso, composição farmacêutica, contentor estéril e kit
EP3434277A1 (en) 2013-06-17 2019-01-30 Armo Biosciences, Inc. Method for assessing protein identity and stability
CN105658232A (zh) 2013-08-30 2016-06-08 阿尔莫生物科技股份有限公司 使用白细胞介素-10治疗疾病和病症的方法
RU2016122957A (ru) 2013-11-11 2017-12-19 Армо Байосайенсиз, Инк. Способы применения интерлейкина-10 для лечения заболеваний и расстройств
US10293043B2 (en) 2014-06-02 2019-05-21 Armo Biosciences, Inc. Methods of lowering serum cholesterol
CA2963989A1 (en) 2014-10-14 2016-04-21 Armo Biosciences, Inc. Interleukin-15 compositions and uses thereof
MX2017004983A (es) 2014-10-22 2017-11-13 Armo Biosciences Inc Metodos para usar interleucina 10 para tratar enfermedades y trastornos.
WO2016126615A1 (en) 2015-02-03 2016-08-11 Armo Biosciences, Inc. Methods of using interleukin-10 for treating diseases and disorders
WO2016191587A1 (en) 2015-05-28 2016-12-01 Armo Biosciences, Inc. Pegylated interleukin-10 for use in treating cancer
US10398761B2 (en) 2015-08-25 2019-09-03 Armo Biosciences, Inc. Methods of using combinations of PEG-IL-10 and IL-15 for treating cancers

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5008374A (en) * 1986-03-14 1991-04-16 Otsuka Pharmaceutical Co., Ltd. IL-1α derivatives and drugs
US5231012A (en) * 1989-06-28 1993-07-27 Schering Corporation Nucleic acids encoding cytokine synthesis inhibitory factor (interleukin-10)
CA2096329A1 (en) * 1990-11-16 1992-05-17 Loretta A. Bober Method for increasing and activating monocytes and neutrophils and for inducing maturation of myeloid cells with interleukin-5
US5658744A (en) * 1994-07-22 1997-08-19 The United States Of America As Represented By The Department Of Health And Human Services Methods of identifying patients having an altered immune status

Also Published As

Publication number Publication date
CA2215968A1 (en) 1996-10-03
WO1996030039A1 (en) 1996-10-03
AU5189096A (en) 1996-10-16
JPH11502533A (ja) 1999-03-02
EP0814829A1 (en) 1998-01-07
AU711087B2 (en) 1999-10-07
NZ304640A (en) 1999-07-29
US5866134A (en) 1999-02-02
MX9707295A (es) 1997-11-29
KR19980703251A (ko) 1998-10-15
HUP9801223A3 (en) 2000-12-28

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