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HUP0201725A3 - Indoloazepines as vasopressin receptor antagonists, their use, pharmaceutical compositions containing them and process for the preparation thereof - Google Patents

Indoloazepines as vasopressin receptor antagonists, their use, pharmaceutical compositions containing them and process for the preparation thereof

Info

Publication number
HUP0201725A3
HUP0201725A3 HU0201725A HUP0201725A HUP0201725A3 HU P0201725 A3 HUP0201725 A3 HU P0201725A3 HU 0201725 A HU0201725 A HU 0201725A HU P0201725 A HUP0201725 A HU P0201725A HU P0201725 A3 HUP0201725 A3 HU P0201725A3
Authority
HU
Hungary
Prior art keywords
indoloazepines
preparation
pharmaceutical compositions
compositions containing
receptor antagonists
Prior art date
Application number
HU0201725A
Other languages
English (en)
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Publication of HUP0201725A2 publication Critical patent/HUP0201725A2/hu
Publication of HUP0201725A3 publication Critical patent/HUP0201725A3/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06Peri-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HU0201725A 1999-06-17 2000-06-15 Indoloazepines as vasopressin receptor antagonists, their use, pharmaceutical compositions containing them and process for the preparation thereof HUP0201725A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13962899P 1999-06-17 1999-06-17
US09/592,520 US6765004B1 (en) 1999-06-17 2000-06-12 Indoloazepines as vasopressin receptor antagonists

Publications (2)

Publication Number Publication Date
HUP0201725A2 HUP0201725A2 (en) 2002-10-28
HUP0201725A3 true HUP0201725A3 (en) 2003-09-29

Family

ID=26837417

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0201725A HUP0201725A3 (en) 1999-06-17 2000-06-15 Indoloazepines as vasopressin receptor antagonists, their use, pharmaceutical compositions containing them and process for the preparation thereof

Country Status (20)

Country Link
US (1) US6765004B1 (hu)
EP (1) EP1214323B1 (hu)
JP (1) JP2003502426A (hu)
CN (1) CN1399638A (hu)
AT (1) ATE282621T1 (hu)
AU (1) AU774768B2 (hu)
BR (1) BR0012294A (hu)
CA (1) CA2375268A1 (hu)
DE (1) DE60015997T2 (hu)
DK (1) DK1214323T3 (hu)
ES (1) ES2233402T3 (hu)
HU (1) HUP0201725A3 (hu)
IL (1) IL147130A0 (hu)
MX (1) MXPA01013286A (hu)
NO (1) NO20016155L (hu)
NZ (1) NZ516209A (hu)
PL (1) PL352998A1 (hu)
PT (1) PT1214323E (hu)
TR (1) TR200200560T2 (hu)
WO (1) WO2000078762A1 (hu)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0324269D0 (en) * 2003-10-16 2003-11-19 Pharmagene Lab Ltd EP4 receptor antagonists
US8567448B2 (en) * 2007-12-26 2013-10-29 Smart Pipe Company, Inc. Methods and systems for in situ pipe lining
US8828989B2 (en) 2011-09-26 2014-09-09 Hoffmann-La Roche Inc. Oxy-cyclohexyl-4H,6H-5-oxa-2,3,10b-triaza-benzo[E]azulenes as V1A antagonists
CN112107568B (zh) * 2019-06-19 2022-03-25 北京龙嘉博创医药科技有限公司 二芳基酰胺类化合物及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3314942A (en) * 1964-08-06 1967-04-18 Upjohn Co 3, 4, 5, 6-tetrahydro-1h-azepino(4, 3, 2-cd) indoles
US3249623A (en) * 1964-09-24 1966-05-03 Upjohn Co Derivatives of 3, 4, 5, 6-tetrahydro-1h-azepino [4, 3, 2-cd] indoles
BE795451A (fr) * 1972-02-23 1973-08-16 Pfizer Agents hypoglycemiants aza indoliques tricycliques
DE3525564A1 (de) 1985-07-15 1987-02-05 Schering Ag Tricyclische verbindungen mit indolstruktur, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
JPS6434988A (en) * 1987-07-30 1989-02-06 Kissei Pharmaceutical Azepinoindole derivative
GB9307527D0 (en) 1993-04-13 1993-06-02 Fujisawa Pharmaceutical Co New venzamide derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same
ES2228405T3 (es) * 1993-07-21 2005-04-16 Yamanouchi Pharmaceutical Co., Ltd. Intermediarios para la produccion de derivados benzazepina condensados.
DE4438178A1 (de) * 1994-10-26 1996-05-02 Bayer Ag N-Methyl-N-isopropyl-heteroaryloxyacetamide

Also Published As

Publication number Publication date
JP2003502426A (ja) 2003-01-21
DE60015997D1 (de) 2004-12-23
ATE282621T1 (de) 2004-12-15
CN1399638A (zh) 2003-02-26
MXPA01013286A (es) 2003-08-20
ES2233402T3 (es) 2005-06-16
TR200200560T2 (tr) 2003-01-21
AU5617000A (en) 2001-01-09
AU774768B2 (en) 2004-07-08
WO2000078762A1 (en) 2000-12-28
NZ516209A (en) 2004-01-30
DK1214323T3 (da) 2005-01-10
PT1214323E (pt) 2005-02-28
US6765004B1 (en) 2004-07-20
EP1214323A1 (en) 2002-06-19
NO20016155D0 (no) 2001-12-17
NO20016155L (no) 2002-02-15
CA2375268A1 (en) 2000-12-28
BR0012294A (pt) 2002-07-02
DE60015997T2 (de) 2005-12-01
IL147130A0 (en) 2002-08-14
EP1214323B1 (en) 2004-11-17
HUP0201725A2 (en) 2002-10-28
PL352998A1 (en) 2003-09-22

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees