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HUP0402112A2 - Eljárás kristályos imipenem előállítására - Google Patents

Eljárás kristályos imipenem előállítására

Info

Publication number
HUP0402112A2
HUP0402112A2 HU0402112A HUP0402112A HUP0402112A2 HU P0402112 A2 HUP0402112 A2 HU P0402112A2 HU 0402112 A HU0402112 A HU 0402112A HU P0402112 A HUP0402112 A HU P0402112A HU P0402112 A2 HUP0402112 A2 HU P0402112A2
Authority
HU
Hungary
Prior art keywords
preparation
imipenem
crystalline imipenem
crystalline
atienamycin
Prior art date
Application number
HU0402112A
Other languages
English (en)
Inventor
Bishwa Prakash Rai
Neera Tewari
Yatendra Kumar
Original Assignee
Ranbaxy Laboratories Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Laboratories Limited filed Critical Ranbaxy Laboratories Limited
Publication of HUP0402112A2 publication Critical patent/HUP0402112A2/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

A jelen találmány tárgya költséghatékony és iparilag előnyös eljárásnagy tisztaságú imipenem előállítására. Az imipenem monohidrát atienamycin N-formimid származéka és (I) szerkezeti képletű: Ó
HU0402112A 2001-11-16 2002-11-18 Eljárás kristályos imipenem előállítására HUP0402112A2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1152DE2001 2001-11-16
PCT/IB2002/004804 WO2003042215A1 (en) 2001-11-16 2002-11-18 Process for the preparation of crystalline imipenem

Publications (1)

Publication Number Publication Date
HUP0402112A2 true HUP0402112A2 (hu) 2005-02-28

Family

ID=11097136

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0402112A HUP0402112A2 (hu) 2001-11-16 2002-11-18 Eljárás kristályos imipenem előállítására

Country Status (15)

Country Link
US (1) US7332600B2 (hu)
EP (1) EP1448563A1 (hu)
JP (1) JP2005509037A (hu)
KR (1) KR20050044506A (hu)
CN (1) CN1608066A (hu)
AR (1) AR037551A1 (hu)
BR (1) BR0214209A (hu)
CA (1) CA2467427A1 (hu)
EA (1) EA200400682A1 (hu)
HR (1) HRP20040552A2 (hu)
HU (1) HUP0402112A2 (hu)
MX (1) MXPA04004604A (hu)
PL (1) PL368984A1 (hu)
WO (1) WO2003042215A1 (hu)
ZA (1) ZA200403961B (hu)

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OA12608A (en) * 2001-05-18 2006-06-08 Ranbaxy Lab Ltd Process for the isolation of crystalline imiponem.
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EP2121604A2 (en) * 2006-12-15 2009-11-25 Schering Corporation Bisulfite purification of an alpha-keto amide
US8621008B2 (en) 2007-04-26 2013-12-31 Mcafee, Inc. System, method and computer program product for performing an action based on an aspect of an electronic mail message thread
US8199965B1 (en) 2007-08-17 2012-06-12 Mcafee, Inc. System, method, and computer program product for preventing image-related data loss
US20130276061A1 (en) 2007-09-05 2013-10-17 Gopi Krishna Chebiyyam System, method, and computer program product for preventing access to data with respect to a data access attempt associated with a remote data sharing session
EP2209787A4 (en) 2007-10-08 2011-08-03 Orchid Chemicals & Pharm Ltd METHOD FOR PRODUCING A CARBAPENEM ANTIBIOTICS
US8893285B2 (en) 2008-03-14 2014-11-18 Mcafee, Inc. Securing data using integrated host-based data loss agent with encryption detection
US9077684B1 (en) 2008-08-06 2015-07-07 Mcafee, Inc. System, method, and computer program product for determining whether an electronic mail message is compliant with an etiquette policy
CN101891744B (zh) * 2010-07-20 2012-06-13 深圳市海滨制药有限公司 亚胺培南一水合物结晶的制备方法
CN101891745B (zh) * 2010-07-20 2012-06-13 深圳市海滨制药有限公司 亚胺培南一水合物晶体的制备方法
WO2012081033A2 (en) * 2010-12-06 2012-06-21 Sequent Scientific Limited A process for preparation of imipenem
CN103524508B (zh) * 2013-09-02 2016-03-30 上海龙翔生物医药开发有限公司 一种亚胺培南一水合物的结晶方法
CN113135916A (zh) * 2020-01-20 2021-07-20 鲁南制药集团股份有限公司 一种亚胺培南制备工艺的除钯方法
CN111747959B (zh) * 2020-05-15 2022-02-11 深圳市海滨制药有限公司 一种亚胺培南原料药的制备方法
CN114671877B (zh) * 2022-02-18 2023-05-16 珠海联邦制药股份有限公司 亚胺培南的精制方法

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Also Published As

Publication number Publication date
JP2005509037A (ja) 2005-04-07
AR037551A1 (es) 2004-11-17
EP1448563A1 (en) 2004-08-25
US7332600B2 (en) 2008-02-19
PL368984A1 (en) 2005-04-04
ZA200403961B (en) 2005-09-19
EA200400682A1 (ru) 2004-10-28
HRP20040552A2 (en) 2004-10-31
BR0214209A (pt) 2004-10-26
CN1608066A (zh) 2005-04-20
KR20050044506A (ko) 2005-05-12
WO2003042215A1 (en) 2003-05-22
CA2467427A1 (en) 2003-05-22
US20050004359A1 (en) 2005-01-06
MXPA04004604A (es) 2004-09-10

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Legal Events

Date Code Title Description
HC9A Change of name, address

Owner name: RANBAXY LABORATORIES LIMITED, IN

Free format text: FORMER OWNER(S): RANBAXY LABORATORIES LIMITED, IN

FD9A Lapse of provisional protection due to non-payment of fees