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HUE051850T2 - Többszörösen telítetlen zsírsavak 2-hidroxi-származékai, gyógyszerként történõ alkalmazásra - Google Patents

Többszörösen telítetlen zsírsavak 2-hidroxi-származékai, gyógyszerként történõ alkalmazásra

Info

Publication number
HUE051850T2
HUE051850T2 HUE16201132A HUE16201132A HUE051850T2 HU E051850 T2 HUE051850 T2 HU E051850T2 HU E16201132 A HUE16201132 A HU E16201132A HU E16201132 A HUE16201132 A HU E16201132A HU E051850 T2 HUE051850 T2 HU E051850T2
Authority
HU
Hungary
Prior art keywords
hidroxyderivates
medicaments
fatty acids
polyunsaturated fatty
polyunsaturated
Prior art date
Application number
HUE16201132A
Other languages
English (en)
Inventor
Ruiz Pablo Vicente Escriba
Xaubet Xavier Busquets
Jimenez Silvia Teres
Coblijn Gwendolyn Barcelo
Caòellas Victoria Llado
Etxenike Amaia Marcilla
Maria Laura Martin
Urbano Monica Higuera
Martinez Rafael Alvarez
Daniel Horacio Lopez
Castillo Catalina Ana Rosello
Garcia Paula Fernandez
Canalejo Manuel Torres
Original Assignee
Lipopharma Therapeutics S L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lipopharma Therapeutics S L filed Critical Lipopharma Therapeutics S L
Publication of HUE051850T2 publication Critical patent/HUE051850T2/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/201Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/661Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/42Unsaturated compounds containing hydroxy or O-metal groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Emergency Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HUE16201132A 2009-03-16 2010-03-15 Többszörösen telítetlen zsírsavak 2-hidroxi-származékai, gyógyszerként történõ alkalmazásra HUE051850T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200900725A ES2345241B1 (es) 2009-03-16 2009-03-16 Uso de 2-hidroxiderivados de acidos grasos poliinsaturados como medicamentos.

Publications (1)

Publication Number Publication Date
HUE051850T2 true HUE051850T2 (hu) 2021-03-29

Family

ID=42673244

Family Applications (2)

Application Number Title Priority Date Filing Date
HUE16201132A HUE051850T2 (hu) 2009-03-16 2010-03-15 Többszörösen telítetlen zsírsavak 2-hidroxi-származékai, gyógyszerként történõ alkalmazásra
HUE10753158A HUE032027T2 (hu) 2009-03-16 2010-03-15 Politelítetlen zsírsavszármazékok gyógyszerként történõ alkalmazása

Family Applications After (1)

Application Number Title Priority Date Filing Date
HUE10753158A HUE032027T2 (hu) 2009-03-16 2010-03-15 Politelítetlen zsírsavszármazékok gyógyszerként történõ alkalmazása

Country Status (19)

Country Link
US (7) US9161928B2 (hu)
EP (2) EP2409963B1 (hu)
JP (1) JP5904592B2 (hu)
KR (4) KR101833772B1 (hu)
CN (4) CN109999018A (hu)
AU (6) AU2010224749B2 (hu)
BR (1) BRPI1009860A8 (hu)
CA (1) CA2754963C (hu)
CL (1) CL2011002268A1 (hu)
DK (2) DK2409963T3 (hu)
ES (3) ES2345241B1 (hu)
HK (1) HK1232207A1 (hu)
HU (2) HUE051850T2 (hu)
MX (1) MX2011009614A (hu)
PL (1) PL2409963T3 (hu)
PT (2) PT2409963T (hu)
RU (1) RU2513995C2 (hu)
SI (1) SI3159329T1 (hu)
WO (1) WO2010106211A1 (hu)

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ES2345241B1 (es) 2009-03-16 2011-09-08 Lipopharma Therapeutics Uso de 2-hidroxiderivados de acidos grasos poliinsaturados como medicamentos.
CA2777827C (en) 2009-10-30 2020-08-18 Retrotope, Inc. Alleviating oxidative stress disorders with pufa derivatives
KR102111997B1 (ko) * 2011-04-26 2020-05-18 레트로토프 인코포레이티드 Pufa와 관련된 신경퇴행성 질환 및 근육 질환
CA2834343C (en) 2011-04-26 2021-10-12 Retrotope, Inc. Disorders implicating pufa oxidation
JP6106158B2 (ja) 2011-04-26 2017-03-29 レトロトップ、 インコーポレイテッドRetrotope, Inc. 酸化的網膜疾患
WO2012148927A2 (en) 2011-04-26 2012-11-01 Retrotope, Inc. Impaired energy processing disorders and mitochondrial deficiency
ES2401629B1 (es) * 2011-10-07 2014-03-04 Universitat De Les Illes Balears Enantiómeros de 2-hidroxiderivados de ácidos grasos y su uso como medicamentos.
CN107428671B (zh) 2014-10-21 2020-12-04 巴利阿里群岛大学 用于合成羟基-三甘油酯的方法及其用于预防和治疗疾病的用途
US20180024150A1 (en) * 2015-03-06 2018-01-25 Niigata University Biomarker of dementia with lewy bodies
CN108698987B (zh) 2015-11-23 2021-07-13 乐巢拓普有限公司 1,4-二烯体系的位点特异性同位素标记
GB201521085D0 (en) * 2015-11-30 2016-01-13 Biozep As Use
WO2018210830A1 (en) 2017-05-16 2018-11-22 Ability Pharmaceuticals S.L. A pharmaceutical combination for the treatment of a cancer
WO2019157516A1 (en) 2018-02-12 2019-08-15 resTORbio, Inc. Combination therapies
LT3813946T (lt) 2018-06-15 2024-07-10 Janssen Pharmaceutica Nv Rapamicino analogai ir jų panaudojimas
CN115209897A (zh) 2019-12-05 2022-10-18 安纳库利亚治疗公司 雷帕霉素类似物及其用途
US20230097753A1 (en) * 2020-01-29 2023-03-30 Universitat De Les Illes Balears Alpha-hydroxylated fatty-acid metabolites, medical uses and use as biomarkers
ES2846824B2 (es) * 2020-01-29 2022-01-19 Univ Illes Balears Profarmacos de acidos grasos poliinsaturados y usos medicos de los mismos
EP4103170A1 (en) 2020-02-10 2022-12-21 Ability Pharmaceuticals S.L. A pharmaceutical combination for the treatment of a cancer
KR20220143931A (ko) 2020-02-21 2022-10-25 레트로토프 인코포레이티드 고도불포화 지방산 및 이의 유도체의 동위원소 변형을 위한 공정
US12109194B2 (en) 2021-02-05 2024-10-08 Biojiva Llc Synergistic combination therapy for treating ALS

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ES2401629B1 (es) * 2011-10-07 2014-03-04 Universitat De Les Illes Balears Enantiómeros de 2-hidroxiderivados de ácidos grasos y su uso como medicamentos.

Also Published As

Publication number Publication date
US9907772B2 (en) 2018-03-06
SI3159329T1 (sl) 2021-01-29
EP2409963A1 (en) 2012-01-25
AU2019226257A1 (en) 2019-09-26
US20180085332A1 (en) 2018-03-29
AU2016238970A1 (en) 2016-11-03
US20160158180A1 (en) 2016-06-09
CA2754963C (en) 2022-02-08
ES2613606T3 (es) 2017-05-24
KR101833772B1 (ko) 2018-03-02
US20120108550A1 (en) 2012-05-03
JP5904592B2 (ja) 2016-04-13
CN106420686A (zh) 2017-02-22
RU2513995C2 (ru) 2014-04-27
HK1232207A1 (zh) 2018-01-05
CN102356057A (zh) 2012-02-15
CN109999018A (zh) 2019-07-12
RU2011141850A (ru) 2013-04-27
EP3159329A1 (en) 2017-04-26
AU2019226257B2 (en) 2020-05-07
CN106420686B (zh) 2020-05-22
DK3159329T3 (da) 2020-11-09
AU2010224749A1 (en) 2011-10-13
DK2409963T3 (en) 2017-02-27
US20170035720A1 (en) 2017-02-09
EP2409963B1 (en) 2017-01-04
CA2754963A1 (en) 2010-09-23
MX2011009614A (es) 2012-01-20
CN106349058A (zh) 2017-01-25
KR20200024953A (ko) 2020-03-09
WO2010106211A1 (es) 2010-09-23
CN106349058B (zh) 2020-01-14
AU2020205213A1 (en) 2020-07-30
ES2820025T3 (es) 2021-04-19
AU2016238970B2 (en) 2018-03-08
US20160158181A1 (en) 2016-06-09
ES2345241B1 (es) 2011-09-08
AU2020205213B2 (en) 2021-02-25
US20200352891A1 (en) 2020-11-12
US11253497B2 (en) 2022-02-22
AU2010224749B2 (en) 2016-07-07
KR20110137365A (ko) 2011-12-22
BRPI1009860A8 (pt) 2019-12-17
AU2018203976A1 (en) 2018-06-21
AU2020205214B2 (en) 2021-02-18
CL2011002268A1 (es) 2012-01-27
PT3159329T (pt) 2020-11-13
KR102233102B1 (ko) 2021-03-26
US9763906B2 (en) 2017-09-19
PT2409963T (pt) 2017-02-15
US20190365690A1 (en) 2019-12-05
BRPI1009860A2 (pt) 2016-03-08
EP3159329B1 (en) 2020-08-12
ES2345241A1 (es) 2010-09-17
KR20180021931A (ko) 2018-03-05
KR20190018754A (ko) 2019-02-25
US10201515B2 (en) 2019-02-12
US9161928B2 (en) 2015-10-20
US9763907B2 (en) 2017-09-19
JP2012520344A (ja) 2012-09-06
HUE032027T2 (hu) 2017-08-28
EP2409963A4 (en) 2013-10-02
AU2020205214A1 (en) 2020-07-30
AU2018203976B2 (en) 2019-06-06
PL2409963T3 (pl) 2017-05-31

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