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HUE048357T2 - Pemetrexedet tartalmazó folyékony gyógyszerészeti kompozíció - Google Patents

Pemetrexedet tartalmazó folyékony gyógyszerészeti kompozíció

Info

Publication number
HUE048357T2
HUE048357T2 HUE15778927A HUE15778927A HUE048357T2 HU E048357 T2 HUE048357 T2 HU E048357T2 HU E15778927 A HUE15778927 A HU E15778927A HU E15778927 A HUE15778927 A HU E15778927A HU E048357 T2 HUE048357 T2 HU E048357T2
Authority
HU
Hungary
Prior art keywords
pemetrexed
pharmaceutical composition
liquid pharmaceutical
liquid
composition
Prior art date
Application number
HUE15778927A
Other languages
English (en)
Inventor
Borek Zaludek
Original Assignee
Synthon Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51844505&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUE048357(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Synthon Bv filed Critical Synthon Bv
Publication of HUE048357T2 publication Critical patent/HUE048357T2/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
HUE15778927A 2014-10-16 2015-10-09 Pemetrexedet tartalmazó folyékony gyógyszerészeti kompozíció HUE048357T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP14189222 2014-10-16

Publications (1)

Publication Number Publication Date
HUE048357T2 true HUE048357T2 (hu) 2020-08-28

Family

ID=51844505

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE15778927A HUE048357T2 (hu) 2014-10-16 2015-10-09 Pemetrexedet tartalmazó folyékony gyógyszerészeti kompozíció

Country Status (12)

Country Link
US (3) US20180235969A1 (hu)
EP (1) EP3206666B1 (hu)
EA (1) EA034559B1 (hu)
ES (1) ES2775582T3 (hu)
HR (1) HRP20200387T1 (hu)
HU (1) HUE048357T2 (hu)
LT (1) LT3206666T (hu)
PL (1) PL3206666T3 (hu)
PT (1) PT3206666T (hu)
RS (1) RS60183B1 (hu)
SI (1) SI3206666T1 (hu)
WO (1) WO2015193517A2 (hu)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2016393213B2 (en) * 2016-02-19 2022-03-31 Eagle Pharmaceuticals, Inc. Pemetrexed formulations
US20170239250A1 (en) 2016-02-19 2017-08-24 Eagle Pharmaceuticals, Inc. Pemetrexed formulations
JP6854710B2 (ja) * 2017-06-14 2021-04-07 日本化薬株式会社 ペメトレキセドを含有する注射用溶液製剤
JP2019094284A (ja) * 2017-11-21 2019-06-20 日本化薬株式会社 ペメトレキセドを含有する注射用溶液製剤
WO2020222151A1 (en) * 2019-05-01 2020-11-05 Intas Pharmaceuticals Ltd. A stable, ready to use aqueous pharmaceutical composition of pemetrexed
JP7282065B2 (ja) 2020-10-05 2023-05-26 イーグル ファーマシューティカルズ, インコーポレイテッド ペメトレキセド製剤

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL96531A (en) 1989-12-11 1995-08-31 Univ Princeton History of Acid N- (Diomeric-H1-Pyrolo] D-2,3 [Pyrimidine-3-Ilacyl (-glutamic, preparation and pharmaceutical preparations containing them)
AU3442201A (en) 2000-02-04 2001-08-14 Eli Lilly And Company Pharmaceutical composition comprising pemetrexed together with monothioglycerol l-cystein or thioglycolic acid
US6686365B2 (en) * 2000-02-04 2004-02-03 Eli Lilly And Company Pharmaceutical composition
CN101081301A (zh) * 2006-05-29 2007-12-05 海南天源康泽医药科技有限公司 含有培美曲塞的药物组合物
CN100522173C (zh) 2006-07-28 2009-08-05 南京依诺维医药科技有限公司 含有培美曲塞的药物组合物
EP2598148A4 (en) * 2010-07-28 2014-05-28 Eagle Pharmaceuticals Inc PHARMACEUTICAL COMPOSITIONS CONTAINING PEMETREXED HAVING EXTENDED STORAGE STABILITY
KR101069128B1 (ko) 2011-03-10 2011-09-30 건일제약 주식회사 페메트렉시드 또는 그의 염을 포함하는 항산화제-비함유 주사용 용액 형태의 약학적 제제의 제조방법
IN2012DE00912A (hu) 2012-03-27 2015-09-11 Fresenius Kabi Oncology Ltd
EP2666463A1 (en) * 2012-05-21 2013-11-27 Synthon BV Stabilized liquid composition comprising pemetrexed
SI2854768T1 (sl) * 2012-05-30 2017-08-31 Fresenius Kabi Oncology Limited Farmacevtski sestavki pemetrekseda
DE102012010774A1 (de) 2012-05-31 2013-12-05 Stada Arzneimittel Ag Pharmazeutische Pemetrexed-Lösung
WO2014198338A1 (en) 2013-06-14 2014-12-18 Synthon B.V. Stable pemetrexed arginine salt and compositions comprising it

Also Published As

Publication number Publication date
SI3206666T1 (sl) 2020-04-30
EP3206666A2 (en) 2017-08-23
US10272090B1 (en) 2019-04-30
WO2015193517A3 (en) 2016-03-10
RS60183B1 (sr) 2020-06-30
ES2775582T3 (es) 2020-07-27
HRP20200387T1 (hr) 2020-06-12
EA201790788A1 (ru) 2017-08-31
US20180271872A1 (en) 2018-09-27
US10188655B2 (en) 2019-01-29
US20180235969A1 (en) 2018-08-23
EA034559B1 (ru) 2020-02-20
PT3206666T (pt) 2020-03-11
US20190105325A1 (en) 2019-04-11
EP3206666B1 (en) 2019-12-11
PL3206666T3 (pl) 2020-09-21
WO2015193517A2 (en) 2015-12-23
LT3206666T (lt) 2020-03-10

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