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HU179474B - Process for preparing solid oral pharmaceutical compositons with increased length of activity and with a regulated release of the active material - Google Patents

Process for preparing solid oral pharmaceutical compositons with increased length of activity and with a regulated release of the active material

Info

Publication number
HU179474B
HU179474B HU78GA1247A HUGA001247A HU179474B HU 179474 B HU179474 B HU 179474B HU 78GA1247 A HU78GA1247 A HU 78GA1247A HU GA001247 A HUGA001247 A HU GA001247A HU 179474 B HU179474 B HU 179474B
Authority
HU
Hungary
Prior art keywords
activity
active material
solid oral
oral pharmaceutical
increased length
Prior art date
Application number
HU78GA1247A
Other languages
English (en)
Inventor
Laszlo Gyarmati
Istvan Racz
Peter Szentmiklosi
Janos Plachy
Original Assignee
Laszlo Gyarmati
Istvan Racz
Peter Szentmiklosi
Janos Plachy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laszlo Gyarmati, Istvan Racz, Peter Szentmiklosi, Janos Plachy filed Critical Laszlo Gyarmati
Priority to HU78GA1247A priority Critical patent/HU179474B/hu
Priority to CA313,227A priority patent/CA1113393A/en
Priority to US05/952,932 priority patent/US4199560A/en
Priority to JP1988579A priority patent/JPS54135219A/ja
Priority to AU44545/79A priority patent/AU521699B2/en
Priority to CH181079A priority patent/CH639845A5/de
Priority to DE19792907215 priority patent/DE2907215A1/de
Priority to FR7904626A priority patent/FR2417982A1/fr
Publication of HU179474B publication Critical patent/HU179474B/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HU78GA1247A 1978-02-24 1978-02-24 Process for preparing solid oral pharmaceutical compositons with increased length of activity and with a regulated release of the active material HU179474B (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
HU78GA1247A HU179474B (en) 1978-02-24 1978-02-24 Process for preparing solid oral pharmaceutical compositons with increased length of activity and with a regulated release of the active material
CA313,227A CA1113393A (en) 1978-02-24 1978-10-12 Solid oral pharmaceutical product with increased efficacy and predetermined steady state of solubility
US05/952,932 US4199560A (en) 1978-02-24 1978-10-19 Solid oral pharmaceutical product with increased efficacy and predetermined steady state of solubility
JP1988579A JPS54135219A (en) 1978-02-24 1979-02-23 Orally dosing solid pharmaceutical preparation and production
AU44545/79A AU521699B2 (en) 1978-02-24 1979-02-23 Solid oral pharmaceutical product
CH181079A CH639845A5 (en) 1978-02-24 1979-02-23 Solid depot pharmaceutical preparations and process for their production
DE19792907215 DE2907215A1 (de) 1978-02-24 1979-02-23 Feste depotarzneimittelpraeparate und verfahren zu deren herstellung
FR7904626A FR2417982A1 (fr) 1978-02-24 1979-02-23 Produit pharmaceutique solide contenant un sel de bismuth, administrable par voie orale, presentant un taux d'activite accru et un taux de solubilite constant et predetermine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU78GA1247A HU179474B (en) 1978-02-24 1978-02-24 Process for preparing solid oral pharmaceutical compositons with increased length of activity and with a regulated release of the active material

Publications (1)

Publication Number Publication Date
HU179474B true HU179474B (en) 1982-10-28

Family

ID=10996479

Family Applications (1)

Application Number Title Priority Date Filing Date
HU78GA1247A HU179474B (en) 1978-02-24 1978-02-24 Process for preparing solid oral pharmaceutical compositons with increased length of activity and with a regulated release of the active material

Country Status (8)

Country Link
US (1) US4199560A (hu)
JP (1) JPS54135219A (hu)
AU (1) AU521699B2 (hu)
CA (1) CA1113393A (hu)
CH (1) CH639845A5 (hu)
DE (1) DE2907215A1 (hu)
FR (1) FR2417982A1 (hu)
HU (1) HU179474B (hu)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2470599A1 (fr) * 1979-12-07 1981-06-12 Panoz Donald Perfectionnements apportes aux procedes de preparation de formes galeniques a action retard et a liberation programmee et formes galeniques de medicaments ainsi obtenus
JPS6056122B2 (ja) * 1980-05-21 1985-12-09 塩野義製薬株式会社 徐放性製剤
US4327076A (en) * 1980-11-17 1982-04-27 Life Savers, Inc. Compressed chewable antacid tablet and method for forming same
US4327077A (en) * 1981-05-29 1982-04-27 Life Savers, Inc. Compressed chewable antacid tablet and method for forming same
US4486412A (en) * 1983-03-15 1984-12-04 Pharmacaps, Inc. Encapsulated antacid dispersions
US4937076A (en) * 1984-08-10 1990-06-26 Combe Incorporated Chewable aspirin and buffering material tablet and method for producing same
AT388101B (de) * 1985-02-05 1989-05-10 Sandoz Ag Verfahren zur herstellung einer pharmazeutischen zusammensetzung zur oralen verabreichung mit kontrollierter wirkstofffreisetzung
AU590578B2 (en) * 1985-04-18 1989-11-09 Procter & Gamble Company, The Treatment of non-ulcer dyspepsia with bismuth salts
DE3686361T3 (de) * 1985-06-13 2003-01-09 Barry James Marshall Verwendung von Bismuth zur Herstellung von Medikamenten zur Behandlung von Magen-Darmstörungen, die von Campylobacter polyridis verursacht sind.
ATE318144T1 (de) * 1985-06-13 2006-03-15 Barry James Marshall Pharmazeutische zusammensetzung zur behandlung gastrointestinaler beschwerden, die wismut und ein antimikrobielles mittel enthält
US4670248A (en) * 1985-08-15 1987-06-02 International Minerals & Chemical Corp. Olivine bolus
US4795642A (en) * 1986-05-01 1989-01-03 Pharmacaps, Inc. Gelatin-encapsulated controlled-release composition
US4708834A (en) * 1986-05-01 1987-11-24 Pharmacaps, Inc. Preparation of gelatin-encapsulated controlled release composition
HU196711B (en) * 1986-06-24 1989-01-30 Istvan Racz Process for producing long-acting, gastric acid neutralizing pharmaceutics with high acid-binding capacity and increased bioavailability
US4656028A (en) * 1986-06-24 1987-04-07 Norcliff Thayer Inc. Encapsulated antacid
DK179687D0 (da) * 1987-04-08 1987-04-08 Farma Food As Praeparat
US4792452A (en) * 1987-07-28 1988-12-20 E. R. Squibb & Sons, Inc. Controlled release formulation
US4994276A (en) * 1988-09-19 1991-02-19 Edward Mendell Co., Inc. Directly compressible sustained release excipient
GB8809421D0 (en) * 1988-04-21 1988-05-25 Fordonal Sa Antacid compositions with prolonged gastric residence time
US5268182A (en) * 1988-06-24 1993-12-07 Abbott Laboratories Sustained-release drug dosage units of terazosin
US5169642A (en) * 1988-06-24 1992-12-08 Abbott Laboratories Sustained-release drug dosage units
US5169639A (en) * 1988-09-19 1992-12-08 Edward Mendell Co., Inc. Controlled release verapamil tablets
US5135757A (en) * 1988-09-19 1992-08-04 Edward Mendell Co., Inc. Compressible sustained release solid dosage forms
DK0540613T3 (da) * 1990-07-20 1996-04-01 Tillotts Pharma Ag Produkter og fremgangsmåder til behandling af fordøjelseskanalen
EP0484106A1 (en) * 1990-11-01 1992-05-06 Merck & Co. Inc. Controlled release formulations
US5368862A (en) * 1991-12-18 1994-11-29 Merck & Co., Inc. Sustained release tablets containing alginate
CA2132012C (en) * 1992-03-25 2003-04-22 John W. Shell Alkyl-substituted cellulose-based sustained-release oral drug dosage forms
US5472711A (en) * 1992-07-30 1995-12-05 Edward Mendell Co., Inc. Agglomerated hydrophilic complexes with multi-phasic release characteristics
SE507682C2 (sv) * 1996-03-29 1998-07-06 Marcin Krotkiewski Farmaceutisk beredning för behandling av gastrit, refluxesofagit, duodenit, dyspepsi och magsårssjukdom innehållande en blandning av ammoniumvismutcitrat och ett alginat
US7022683B1 (en) * 1998-05-13 2006-04-04 Carrington Laboratories, Inc. Pharmacological compositions comprising pectins having high molecular weights and low degrees of methoxylation
FR2779651B1 (fr) * 1998-06-16 2001-04-20 Gattefosse Ets Sa Procede pour la fabrication de comprimes a liberation prolongee de principe(s) actif(s) presentant une cinetique de dissolution d'ordre zero
US7494669B2 (en) * 2001-02-28 2009-02-24 Carrington Laboratories, Inc. Delivery of physiological agents with in-situ gels comprising anionic polysaccharides
US6777000B2 (en) * 2001-02-28 2004-08-17 Carrington Laboratories, Inc. In-situ gel formation of pectin
US20090142398A1 (en) * 2007-11-21 2009-06-04 Pharmascience Inc. Novel pharmaceutical compositions comprising a disintegration matrix

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2166868A (en) * 1936-03-02 1939-07-18 Columbus Pharmacal Company Colloidal aluminum hydroxide
US2146867A (en) * 1937-06-07 1939-02-14 Welin Sater Company Medicinal preparation and method of making the same
US2836540A (en) * 1952-03-19 1958-05-27 Hardt Foundation Pharmaceutical antacid composition
US2774710A (en) * 1952-12-15 1956-12-18 Organon Pharmaceutical preparation for the treatment of hyperacidity
US2793979A (en) * 1953-03-30 1957-05-28 Smith Kline French Lab Method of making a sustained release pharmaceutical tablet and product of the method
US2854376A (en) * 1954-09-07 1958-09-30 Hardt Foundation Antacid composition
US2805977A (en) * 1955-01-04 1957-09-10 Smith Kline French Lab Sustained release pharmaceutical preparation
US2875130A (en) * 1956-11-20 1959-02-24 Smith Kline French Lab Method of preparing sustained release particles and the product of the method
US3079303A (en) * 1958-12-11 1963-02-26 Smith Kline French Lab Basic tablet granulation and process of using same
US3062720A (en) * 1959-05-20 1962-11-06 Philips Roxane Sustained release pharmaceutical tablet
US3108046A (en) * 1960-11-25 1963-10-22 Smith Kline French Lab Method of preparing high dosage sustained release tablet and product of this method
US3175942A (en) * 1962-03-13 1965-03-30 Evans Medical Ltd Gastro-intestinal therapeutic
US3362880A (en) * 1963-09-20 1968-01-09 Dow Chemical Co Compressed drug tablets of ethyl cellulose, glyceryl monostearate, karaya gum, tragacanth, talc, and magnesium stearate
US3555151A (en) * 1966-12-21 1971-01-12 Richardson Merrell Inc Long acting solid antacid
US3579634A (en) * 1968-04-18 1971-05-18 Garland Richard Brown Novel antacid compositions and methods for their administration
US3579635A (en) * 1969-10-08 1971-05-18 Lilly Co Eli Antibiotic treatment of ruminant animals with bis-urea adducts of aldehyde-containing macrolide antibiotics
DE1963496A1 (de) * 1969-12-18 1971-06-24 Hans Voigt Chemisch Pharmazeut Pharmazeutisches Praeparat zur Behandlung von Magen-Darm-Erkrankungen
FR2146915A1 (en) * 1971-07-26 1973-03-09 Cerm Cent Europ Rech Mauvernay Basic bismuth salts of xanthane gums - as pharmaceutical excipients
GB1390683A (en) * 1972-12-18 1975-04-16 Biorex Laboratories Ltd Pharmaceutical composition
GB1413186A (en) * 1973-06-27 1975-11-12 Toyo Jozo Kk Process for encapsulation of medicaments
ZA74385B (en) * 1974-01-18 1975-08-27 Gist Brocades Nv Pharmaceutical compositions

Also Published As

Publication number Publication date
CA1113393A (en) 1981-12-01
JPS54135219A (en) 1979-10-20
AU521699B2 (en) 1982-04-22
AU4454579A (en) 1979-08-30
FR2417982B1 (hu) 1984-11-30
US4199560A (en) 1980-04-22
DE2907215A1 (de) 1979-09-06
CH639845A5 (en) 1983-12-15
FR2417982A1 (fr) 1979-09-21

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HMM4 Cancellation of final prot. due to non-payment of fee