HRP931109A2 - Remineralizing tooth-care agent - Google Patents

Remineralizing tooth-care agent Download PDF

Info

Publication number: HRP931109A2
Authority: HR; Croatia
Prior art keywords: toothpaste; pct; polishing; acids; magnesium
Prior art date: 1992-11-06

Application number

HR931109A

Other languages

English (en)

Croatian (hr)

Inventor

Klaus Schumann

Franz Forg

Hans Laska

Original Assignee

Henkel Kgaa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-11-06

Filing date

1993-08-09

Publication date

1995-06-30

1993-08-09 Application filed by Henkel Kgaa filed Critical Henkel Kgaa

1995-06-30 Publication of HRP931109A2 publication Critical patent/HRP931109A2/hr

Links

230000000395 remineralizing effect Effects 0.000 title description 3
239000000606 toothpaste Substances 0.000 claims abstract description 35
229940034610 toothpaste Drugs 0.000 claims abstract description 28
238000005498 polishing Methods 0.000 claims abstract description 21
RBLGLDWTCZMLRW-UHFFFAOYSA-K dicalcium;phosphate;dihydrate Chemical compound O.O.[Ca+2].[Ca+2].[O-]P([O-])([O-])=O RBLGLDWTCZMLRW-UHFFFAOYSA-K 0.000 claims abstract description 16
XAAHAAMILDNBPS-UHFFFAOYSA-L calcium hydrogenphosphate dihydrate Chemical compound O.O.[Ca+2].OP([O-])([O-])=O XAAHAAMILDNBPS-UHFFFAOYSA-L 0.000 claims abstract description 4
235000012239 silicon dioxide Nutrition 0.000 claims description 26
239000003795 chemical substances by application Substances 0.000 claims description 23
RMAQACBXLXPBSY-UHFFFAOYSA-N silicic acid Chemical compound O[Si](O)(O)O RMAQACBXLXPBSY-UHFFFAOYSA-N 0.000 claims description 17
125000005624 silicic acid group Chemical class 0.000 claims description 9
150000002222 fluorine compounds Chemical class 0.000 claims description 7
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
239000011230 binding agent Substances 0.000 claims description 4
239000011777 magnesium Substances 0.000 claims description 3
159000000003 magnesium salts Chemical class 0.000 claims description 3
QJLVYSQIYAHNJO-UHFFFAOYSA-L magnesium;fluoro-dioxido-oxo-$l^{5}-phosphane Chemical compound [Mg+2].[O-]P([O-])(F)=O QJLVYSQIYAHNJO-UHFFFAOYSA-L 0.000 claims description 3
239000002245 particle Substances 0.000 claims description 3
229910052749 magnesium Inorganic materials 0.000 claims description 2
229940074371 monofluorophosphate Drugs 0.000 claims description 2
FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims 1
-1 fluorophosphate ions Chemical class 0.000 abstract description 7
JLVVSXFLKOJNIY-UHFFFAOYSA-N Magnesium ion Chemical compound [Mg+2] JLVVSXFLKOJNIY-UHFFFAOYSA-N 0.000 abstract description 3
229910001425 magnesium ion Inorganic materials 0.000 abstract description 3
210000004268 dentin Anatomy 0.000 description 10
239000000126 substance Substances 0.000 description 10
239000002253 acid Substances 0.000 description 9
150000007513 acids Chemical class 0.000 description 7
210000003298 dental enamel Anatomy 0.000 description 7
229910052588 hydroxylapatite Inorganic materials 0.000 description 6
XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 description 6
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 5
229920001223 polyethylene glycol Polymers 0.000 description 5
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 4
CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 4
125000000217 alkyl group Chemical group 0.000 description 4
230000000052 comparative effect Effects 0.000 description 4
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125000004432 carbon atom Chemical group C* 0.000 description 3
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230000001580 bacterial effect Effects 0.000 description 2
FUFJGUQYACFECW-UHFFFAOYSA-L calcium hydrogenphosphate Chemical compound [Ca+2].OP([O-])([O-])=O FUFJGUQYACFECW-UHFFFAOYSA-L 0.000 description 2
239000013078 crystal Substances 0.000 description 2
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150000004665 fatty acids Chemical class 0.000 description 2
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159000000011 group IA salts Chemical class 0.000 description 2
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XLYOFNOQVPJJNP-ZSJDYOACSA-N heavy water Substances [2H]O[2H] XLYOFNOQVPJJNP-ZSJDYOACSA-N 0.000 description 2
238000011065 in-situ storage Methods 0.000 description 2
JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
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235000019341 magnesium sulphate Nutrition 0.000 description 2
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239000006072 paste Substances 0.000 description 2
238000001556 precipitation Methods 0.000 description 2
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150000003839 salts Chemical class 0.000 description 2
NTHWMYGWWRZVTN-UHFFFAOYSA-N sodium silicate Chemical compound [Na+].[Na+].[O-][Si]([O-])=O NTHWMYGWWRZVTN-UHFFFAOYSA-N 0.000 description 2
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239000001605 (5-methyl-2-propan-2-ylcyclohexyl) acetate Substances 0.000 description 1
KJPRLNWUNMBNBZ-QPJJXVBHSA-N (E)-cinnamaldehyde Chemical compound O=C\C=C\C1=CC=CC=C1 KJPRLNWUNMBNBZ-QPJJXVBHSA-N 0.000 description 1
OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 description 1
TYBHZVUFOINFDV-UHFFFAOYSA-N 2-bromo-6-[(3-bromo-5-chloro-2-hydroxyphenyl)methyl]-4-chlorophenol Chemical compound OC1=C(Br)C=C(Cl)C=C1CC1=CC(Cl)=CC(Br)=C1O TYBHZVUFOINFDV-UHFFFAOYSA-N 0.000 description 1
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XGRSAFKZAGGXJV-UHFFFAOYSA-N 3-azaniumyl-3-cyclohexylpropanoate Chemical compound OC(=O)CC(N)C1CCCCC1 XGRSAFKZAGGXJV-UHFFFAOYSA-N 0.000 description 1
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235000021317 phosphate Nutrition 0.000 description 1
150000003013 phosphoric acid derivatives Chemical class 0.000 description 1
239000000049 pigment Substances 0.000 description 1
239000001622 pimenta officinalis fruit oil Substances 0.000 description 1
229920001451 polypropylene glycol Polymers 0.000 description 1
229920002451 polyvinyl alcohol Polymers 0.000 description 1
229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
239000001267 polyvinylpyrrolidone Substances 0.000 description 1
235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
238000002360 preparation method Methods 0.000 description 1
239000003755 preservative agent Substances 0.000 description 1
CMDGQTVYVAKDNA-UHFFFAOYSA-N propane-1,2,3-triol;hydrate Chemical compound O.OCC(O)CO CMDGQTVYVAKDNA-UHFFFAOYSA-N 0.000 description 1
125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
235000013772 propylene glycol Nutrition 0.000 description 1
229920006395 saturated elastomer Polymers 0.000 description 1
230000035945 sensitivity Effects 0.000 description 1
150000004760 silicates Chemical class 0.000 description 1
229910052710 silicon Inorganic materials 0.000 description 1
239000010703 silicon Substances 0.000 description 1
239000000377 silicon dioxide Substances 0.000 description 1
239000011734 sodium Substances 0.000 description 1
229910052708 sodium Inorganic materials 0.000 description 1
WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 description 1
235000010234 sodium benzoate Nutrition 0.000 description 1
239000004299 sodium benzoate Substances 0.000 description 1
229960001462 sodium cyclamate Drugs 0.000 description 1
229960004711 sodium monofluorophosphate Drugs 0.000 description 1
159000000000 sodium salts Chemical class 0.000 description 1
LROWVYNUWKVTCU-STWYSWDKSA-M sodium sorbate Chemical compound [Na+].C\C=C\C=C\C([O-])=O LROWVYNUWKVTCU-STWYSWDKSA-M 0.000 description 1
235000019250 sodium sorbate Nutrition 0.000 description 1
RPACBEVZENYWOL-XFULWGLBSA-M sodium;(2r)-2-[6-(4-chlorophenoxy)hexyl]oxirane-2-carboxylate Chemical compound [Na+].C=1C=C(Cl)C=CC=1OCCCCCC[C@]1(C(=O)[O-])CO1 RPACBEVZENYWOL-XFULWGLBSA-M 0.000 description 1
239000005720 sucrose Substances 0.000 description 1
AGGIJOLULBJGTQ-UHFFFAOYSA-N sulfoacetic acid Chemical compound OC(=O)CS(O)(=O)=O AGGIJOLULBJGTQ-UHFFFAOYSA-N 0.000 description 1
239000000725 suspension Substances 0.000 description 1
239000003765 sweetening agent Substances 0.000 description 1
208000024891 symptom Diseases 0.000 description 1
239000004408 titanium dioxide Substances 0.000 description 1
235000010487 tragacanth Nutrition 0.000 description 1
239000000196 tragacanth Substances 0.000 description 1
229940116362 tragacanth Drugs 0.000 description 1
QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical class [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
230000004222 uncontrolled growth Effects 0.000 description 1
MWOOGOJBHIARFG-UHFFFAOYSA-N vanillin Chemical compound COC1=CC(C=O)=CC=C1O MWOOGOJBHIARFG-UHFFFAOYSA-N 0.000 description 1
FGQOOHJZONJGDT-UHFFFAOYSA-N vanillin Natural products COC1=CC(O)=CC(C=O)=C1 FGQOOHJZONJGDT-UHFFFAOYSA-N 0.000 description 1
235000012141 vanillin Nutrition 0.000 description 1
229940117960 vanillin Drugs 0.000 description 1
238000005406 washing Methods 0.000 description 1
229920003169 water-soluble polymer Polymers 0.000 description 1
239000000811 xylitol Substances 0.000 description 1
235000010447 xylitol Nutrition 0.000 description 1
HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
229960002675 xylitol Drugs 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
- A61K8/21—Fluorides; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/24—Phosphorous; Compounds thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/25—Silicon; Compounds thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Inorganic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Birds (AREA)
Oral & Maxillofacial Surgery (AREA)
Cosmetics (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Dental Preparations (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Detergent Compositions (AREA)

HR931109A 1992-11-06 1993-08-09 Remineralizing tooth-care agent HRP931109A2 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE4237500A DE4237500A1 (de)	1992-11-06	1992-11-06	Remineralisierendes Zahnpflegemittel

Publications (1)

Publication Number	Publication Date
HRP931109A2 true HRP931109A2 (en)	1995-06-30

Family

ID=6472268

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HR931109A HRP931109A2 (en)	1992-11-06	1993-08-09	Remineralizing tooth-care agent

Country Status (22)

Country	Link
US (1)	US5605677A (fi)
EP (1)	EP0666730B1 (fi)
JP (1)	JPH08502988A (fi)
KR (1)	KR100295937B1 (fi)
CN (1)	CN1047304C (fi)
AT (1)	ATE166225T1 (fi)
BG (1)	BG99417A (fi)
CA (1)	CA2148909C (fi)
CZ (1)	CZ287746B6 (fi)
DE (2)	DE4237500A1 (fi)
DK (1)	DK0666730T3 (fi)
ES (1)	ES2117153T3 (fi)
FI (1)	FI952110A (fi)
HR (1)	HRP931109A2 (fi)
HU (1)	HU218972B (fi)
LT (1)	LT3075B (fi)
LV (1)	LV11427A (fi)
NO (1)	NO308933B1 (fi)
PL (1)	PL172151B1 (fi)
SI (1)	SI9300478A (fi)
SK (1)	SK280006B6 (fi)
WO (1)	WO1994010969A1 (fi)

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US5658553A (en) *	1995-05-02	1997-08-19	The Procter & Gamble Company	Dentifrice compositions
US5651958A (en) *	1995-05-02	1997-07-29	The Procter & Gamble Company	Dentifrice compositions
US6036944A (en) *	1995-08-08	2000-03-14	Enamelon, Inc.	Processes for the remineralization and mineralization of teeth
US6159449A (en) *	1997-04-03	2000-12-12	Enamelon, Inc.	Dentifrice products and methods for remineralizing and/or mineralizing teeth
EP0870493A1 (en) *	1997-04-11	1998-10-14	Carter-Wallace, Inc.	Oral gel composition comprising hydrated silica
WO1998052524A1 (en) *	1997-05-19	1998-11-26	Colgate-Palmolive Company	Fluoride free dental remineralization
DE19740453A1 (de) *	1997-09-15	1999-03-18	Henkel Kgaa	Zahnreinigungsmittel
US6294155B1 (en) *	1998-04-08	2001-09-25	W. R. Grace & Co. -Conn.	Abrasive silica compositions and dentifrice compositions prepared therefrom
DE19831547A1 (de) *	1998-07-14	2000-01-20	Henkel Kgaa	Flüssige Zahnreinigungsmittel
AUPP494798A0 (en) *	1998-07-29	1998-08-20	Pacific Biolink Pty Limited	Protective protein formulation
US7625855B2 (en) *	1999-08-11	2009-12-01	Gonzalez Gustavo M	Cleaning compositions for removing organic deposits in hard to reach surfaces
US6303104B1 (en)	1999-02-12	2001-10-16	Enamelon, Inc.	Remineralizing/mineralizing oral products having improved whitening and stain removal properties
US6485708B1 (en)	1999-05-13	2002-11-26	Church & Dwight Co. Inc.	Products and methods for the remineralization and prevention of demineralization of teeth
US6685920B2 (en) *	1999-11-12	2004-02-03	The Procter & Gamble Company	Method of protecting teeth against erosion
US6174515B1 (en)	2000-06-05	2001-01-16	Amway Corporation	Toothpaste composition
US6652611B1 (en) *	2000-08-18	2003-11-25	J. M. Huber Corporation	Method for making abrasive compositions and products thereof
US6372198B1 (en)	2000-09-14	2002-04-16	Joseph M. Abbate	Dentifrice for the mineralization and remineralization of teeth
KR20030017797A (ko) *	2001-08-22	2003-03-04	(주) 시온텍	치아우식증(충치)예방을 위한 불소이온 용출 필터소재 및그 응용방법
DE10223157C1 (de)	2002-05-24	2003-10-23	Max Planck Gesellschaft	Induzierte Remineralisation von humanem Zahnschmelz
BRPI0413535A (pt)	2003-09-09	2006-10-10	Dsm Ip Assets Bv	agente tópico essencialmente anidro com atividade oral compreendendo uma ou mais substáncias sensìveis à oxidação
US20050084461A1 (en) *	2003-10-16	2005-04-21	Winston Anthony E.	Tooth enamel rejuvenating toothpaste
US20070258916A1 (en) *	2006-04-14	2007-11-08	Oregon Health & Science University	Oral compositions for treating tooth hypersensitivity
US20090186090A1 (en) *	2007-04-30	2009-07-23	Colgate-Palmolive	Oral Care Composition to Reduce or Eliminate Dental Sensitivity
US20080267891A1 (en) *	2007-04-30	2008-10-30	Colgate-Palmolive Company	Oral Care Composition To Reduce Or Eliminate Dental Sensitivity
US7850453B2 (en) *	2007-08-08	2010-12-14	Coll Partners Ltd.	Reshapable device for fixation at a dental site
MY158777A (en)	2009-05-18	2016-11-15	Colgate Palmolive Co	Oral compositions containing polyguanidinium compounds and methods of manufacture and use thereof
US8741268B2 (en) *	2009-09-10	2014-06-03	Preventive Technologies, Inc.	Dental prophylactic paste
TWI499430B (zh)	2009-12-17	2015-09-11	Colgate Palmolive Co	抗侵蝕的牙膏組成物
AU2011210805C1 (en)	2010-01-29	2015-09-17	Colgate-Palmolive Company	Oral care product for sensitive enamel care
GB201016970D0 (en) *	2010-10-08	2010-11-24	Univ Leeds	Composition
WO2013142996A1 (en) *	2012-03-30	2013-10-03	The Royal Institution For The Advancement Of Learning/Mcgill University	Magnesium phosphate gels
DE102013109847A1 (de)	2013-09-09	2015-03-12	Heraeus Kulzer Gmbh	Formulierungen und Kit zur biomimetischen Abscheidung von Apatit auf Zähnen
DE102013109848A1 (de)	2013-09-09	2015-03-12	Heraeus Kulzer Gmbh	Applikationssystem zur einfachen, 3-dimensionalen Anwendung von medizinischen, kosmetischen oder Arzneimittel enthaltenden Zahnpflegeprodukten
DE102013109846A1 (de)	2013-09-09	2015-03-12	Heraeus Kulzer Gmbh	Formulierungen und Kit zur biomimetischen Abscheidung von Apatit auf Zähnen
US9668844B2 (en)	2013-11-06	2017-06-06	Colldent Y.A Ltd	Device for fixation at a dental site
ES2929118T3 (es) *	2015-12-10	2022-11-24	Invicare Inc	Hidrogeles de fosfato de magnesio
CN111615378A (zh)	2018-01-17	2020-09-01	宝洁公司	用于提高釉质硬度和抵抗力的方法和组合物
CN111658561B (zh) *	2019-03-08	2023-04-11	湖北中部医疗科技有限公司	一种抗牙齿敏感牙膏及其制备方法
CN115339121B (zh) *	2021-05-12	2024-06-07	华侨大学	一种柔性溶胶凝胶抛光块体的制备方法

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US4097588A (en) *	1975-03-11	1978-06-27	National Research Development Corporation	Mineralizing dental mouthrinse
DE2526808A1 (de) *	1975-06-16	1977-01-20	Henkel & Cie Gmbh	Fluorhaltige zahnpasta fuer druckgasverpackung
US4024239A (en) *	1975-07-03	1977-05-17	Lever Brothers Company	Toothpaste composition
BR7700632A (pt) *	1976-02-05	1977-10-04	Grace W R & Co	Processo para preparar uma composicao oral de pasta de dentes
US4412983A (en) *	1977-02-22	1983-11-01	Colgate-Palmolive Company	Dentifrices containing amorphous silica
US4183914A (en) *	1977-12-19	1980-01-15	Abdul Gaffar	Magnesium polycarboxylate complexes and anticalculus agents
EP0040938A3 (en) *	1980-05-19	1981-12-16	Monsanto Company	Prophylactic dental paste comprising dicalcium phosphate and method of using it for cleaning, polishing and remineralizing teeth
US4348382A (en) *	1980-12-05	1982-09-07	Colgate-Palmolive Company	Dentifrice composition
DE3114493A1 (de) *	1981-04-10	1982-10-28	Degussa Ag, 6000 Frankfurt	"faellungskieselsaeuren und verfahren zu ihrer herstellung"
DE3114492A1 (de) *	1981-04-10	1982-10-28	Degussa Ag, 6000 Frankfurt	Zahnpflegemittel
US4425324A (en) *	1981-05-11	1984-01-10	Colgate-Palmolive Company	Hazed toothpaste
US4472365A (en) *	1981-06-15	1984-09-18	Stauffer Chemical Company	Dicalcium phosphate dihydrate having improved monofluorophosphate compatibility and process for the preparation thereof
US4411876A (en) *	1982-12-30	1983-10-25	Stauffer Chemical Company	Process for the manufacture of trimagnesium phosphate octahydrate of high purity
US4565692A (en) *	1983-12-23	1986-01-21	Colgate-Palmolive Company	Extrudable dentifrice
US5037636A (en) *	1989-10-23	1991-08-06	Monsanto Chemical Company	Fluoride stability in dicalcium phosphate dihydrate composition

1992
- 1992-11-06 DE DE4237500A patent/DE4237500A1/de not_active Withdrawn
1993
- 1993-08-09 HR HR931109A patent/HRP931109A2/hr not_active Application Discontinuation
- 1993-09-16 SI SI9300478A patent/SI9300478A/sl unknown
- 1993-10-28 WO PCT/EP1993/002991 patent/WO1994010969A1/de active IP Right Grant
- 1993-10-28 CZ CZ19951172A patent/CZ287746B6/cs not_active IP Right Cessation
- 1993-10-28 SK SK565-95A patent/SK280006B6/sk unknown
- 1993-10-28 DE DE59308590T patent/DE59308590D1/de not_active Expired - Lifetime
- 1993-10-28 HU HU9501325A patent/HU218972B/hu not_active IP Right Cessation
- 1993-10-28 JP JP6511652A patent/JPH08502988A/ja active Pending
- 1993-10-28 CA CA002148909A patent/CA2148909C/en not_active Expired - Lifetime
- 1993-10-28 KR KR1019950700803A patent/KR100295937B1/ko not_active IP Right Cessation
- 1993-10-28 AT AT93923565T patent/ATE166225T1/de not_active IP Right Cessation
- 1993-10-28 EP EP93923565A patent/EP0666730B1/de not_active Expired - Lifetime
- 1993-10-28 US US08/433,391 patent/US5605677A/en not_active Expired - Fee Related
- 1993-10-28 DK DK93923565T patent/DK0666730T3/da active
- 1993-10-28 ES ES93923565T patent/ES2117153T3/es not_active Expired - Lifetime
- 1993-10-28 PL PL93308767A patent/PL172151B1/pl not_active IP Right Cessation
- 1993-11-05 LT LTIP1437A patent/LT3075B/lt not_active IP Right Cessation
- 1993-11-05 CN CN93114226A patent/CN1047304C/zh not_active Expired - Fee Related
1995
- 1995-01-20 NO NO950229A patent/NO308933B1/no not_active IP Right Cessation
- 1995-02-13 BG BG99417A patent/BG99417A/bg unknown
- 1995-05-03 FI FI952110A patent/FI952110A/fi unknown
- 1995-05-05 LV LV950124A patent/LV11427A/xx unknown

Also Published As

Publication number	Publication date
LV11427A (lv)	1996-08-20
PL308767A1 (en)	1995-08-21
SK56595A3 (en)	1997-01-08
NO950229L (no)	1995-01-20
ES2117153T3 (es)	1998-08-01
CZ117295A3 (en)	1995-11-15
HUT70078A (en)	1995-09-28
EP0666730B1 (de)	1998-05-20
US5605677A (en)	1997-02-25
DE4237500A1 (de)	1994-05-11
SK280006B6 (sk)	1999-07-12
DK0666730T3 (da)	1999-03-08
BG99417A (bg)	1995-06-30
PL172151B1 (pl)	1997-08-29
HU9501325D0 (en)	1995-06-28
JPH08502988A (ja)	1996-04-02
CN1090751A (zh)	1994-08-17
CN1047304C (zh)	1999-12-15
LT3075B (en)	1994-11-25
DE59308590D1 (de)	1998-06-25
CZ287746B6 (en)	2001-01-17
HU218972B (hu)	2001-01-29
KR100295937B1 (ko)	2001-11-14
CA2148909C (en)	2003-06-10
NO950229D0 (no)	1995-01-20
ATE166225T1 (de)	1998-06-15
WO1994010969A1 (de)	1994-05-26
FI952110A0 (fi)	1995-05-03
FI952110A (fi)	1995-05-03
LTIP1437A (en)	1994-05-15
SI9300478A (en)	1994-06-30
NO308933B1 (no)	2000-11-20
CA2148909A1 (en)	1994-05-26
EP0666730A1 (de)	1995-08-16

Publication	Publication Date	Title
HRP931109A2 (en)	1995-06-30	Remineralizing tooth-care agent
AU2016285678B2 (en)	2018-06-14	Oral care compositions and methods of use
RU2337734C2 (ru)	2008-11-10	Ультрамягкое средство для гигиенического ухода за полостью рта против чувствительности, кариеса, окрашивания и зубного налета
EP3344215B1 (en)	2021-05-19	Oral care compositions and methods of use
JP6199871B2 (ja)	2017-09-20	口腔用組成物
WO1992010993A1 (en)	1992-07-09	Oral compositions
JPH09503506A (ja)	1997-04-08	オーラル組成物
JP2008260702A (ja)	2008-10-30	再石灰化促進剤及び口腔用組成物
US10039698B2 (en)	2018-08-07	Toothpaste composition
JPH01207227A (ja)	1989-08-21	歯石予防組成物
CN110769801B (zh)	2022-10-14	口腔护理组合物
EP0695165A1 (en)	1996-02-07	Method of making a tartar control baking soda dentifrice
GB2151478A (en)	1985-07-24	Antiplaque/antigingivitis compositions
AU2015411327B2 (en)	2019-05-30	Oral care compositions
WO2014054257A1 (ja)	2014-04-10	歯磨用組成物
CA3141540A1 (en)	2020-12-30	Oral care compositions and methods of use
EP3484435A1 (en)	2019-05-22	Oral care composition comprising composite particles containing cationic germicide
WO1994000102A1 (en)	1994-01-06	Anticalculus compositions
WO2021047971A1 (en)	2021-03-18	Method for remineralizing and/or reducing sensitivity of teeth
EP1239821A2 (de)	2002-09-18	Zahnreinigungsmittel
JP2003518031A (ja)	2003-06-03	歯磨き剤

Legal Events

Date	Code	Title
1995-06-30	A1OB	Publication of a patent application
1995-12-01	AIPI	Request for the grant of a patent on the basis of a substantive examination of a patent application
2000-06-15	ODBC	Application rejected