HRP970166A2 - Substituted 1,2,3,4-tetrahydronaphthalene derivatives - Google Patents

Substituted 1,2,3,4-tetrahydronaphthalene derivatives

Info

Publication number: HRP970166A2
Authority: HR; Croatia
Prior art keywords: substituted; tetrahydronaphthalene derivatives; tetrahydronaphthalene; derivatives
Prior art date: 1996-03-22

Application number

HR9601110-1A

Other languages

English (en)

Inventor

Stefan Berg

Lenart Florvall

Ross Svante

Thorberg Seth-Olov

Original Assignee

Astra Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-03-22

Filing date

1997-03-21

Publication date

1998-04-30

1997-03-21 Application filed by Astra Ab filed Critical Astra Ab

1998-04-30 Publication of HRP970166A2 publication Critical patent/HRP970166A2/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/112—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/205—Radicals derived from carbonic acid
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Epidemiology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

HR9601110-1A 1996-03-22 1997-03-21 Substituted 1,2,3,4-tetrahydronaphthalene derivatives HRP970166A2 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
SE9601110A SE9601110D0 (sv)	1996-03-22	1996-03-22	Substituted 1,2,3,4-tetrahydronaphthalene derivatives

Publications (1)

Publication Number	Publication Date
HRP970166A2 true HRP970166A2 (en)	1998-04-30

Family

ID=20401907

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HR9601110-1A HRP970166A2 (en)	1996-03-22	1997-03-21	Substituted 1,2,3,4-tetrahydronaphthalene derivatives

Country Status (27)

Country	Link
US (2)	US6124283A (de)
EP (1)	EP0888319B1 (de)
JP (1)	JP2000506883A (de)
KR (1)	KR20000064751A (de)
CN (1)	CN1073101C (de)
AR (2)	AR006360A1 (de)
AT (1)	ATE231847T1 (de)
AU (1)	AU709856B2 (de)
BR (1)	BR9708093A (de)
CA (1)	CA2247940A1 (de)
CZ (1)	CZ301998A3 (de)
DE (1)	DE69718771T2 (de)
EE (1)	EE9800300A (de)
HR (1)	HRP970166A2 (de)
HU (1)	HUP9902454A3 (de)
ID (1)	ID16298A (de)
IL (2)	IL126070A0 (de)
IS (1)	IS4844A (de)
NO (1)	NO311803B1 (de)
NZ (1)	NZ331613A (de)
PL (1)	PL329121A1 (de)
SE (1)	SE9601110D0 (de)
SK (1)	SK282359B6 (de)
TR (1)	TR199801868T2 (de)
WO (1)	WO1997034883A1 (de)
YU (1)	YU40998A (de)
ZA (1)	ZA972056B (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE9900190D0 (sv) *	1999-01-22	1999-01-22	Astra Ab	New compounds
SE9702799D0 (sv)	1997-07-25	1997-07-25	Astra Ab	New compounds
SE9703379D0 (sv) *	1997-09-18	1997-09-18	Astra Ab	New compounds
SE9703376D0 (sv) *	1997-09-18	1997-09-18	Astra Ab	A new combination
SE9703374D0 (sv) *	1997-09-18	1997-09-18	Astra Ab	A new combination
SE9703375D0 (sv) *	1997-09-18	1997-09-18	Astra Ab	A new combination
DE69919436T2 (de)	1998-04-16	2005-09-15	Pfizer Products Inc., Groton	N-Acyl und N-Aroyl Aralkylamide
SE0002729D0 (sv) *	2000-07-20	2000-07-20	Astrazeneca Ab	Novel compound form
BR0206512A (pt)	2001-01-16	2004-01-06	Astrazeneca Ab	Composto, método de tratamento de um ser humano ou animal que sofre de depressão, ansiedade generalizada, distúrbios da alimentação, demência, distúrbio do p nico, distúrbios do sono, distúrbios gastrointestinais, distúrbios motores, distúrbios endócrinos, vasoespasmo e disfunção sexual, uso de um composto, e, processo para preparar um composto.
BR0206513A (pt)	2001-01-16	2004-01-06	Astrazeneca Ab	Composição, métodos de tratamento de um ser humano ou animal que sofre de depressão, ansiedade generalizada, distúrbios da alimentação, demência, distúrbio do p nico, distúrbios do sono, distúrbios gastrointestinais, distúrbios motores, distúrbios endócrinos, vasoespasmo e disfunção sexual, uso de qualquer um dos compostos, composição farmacêutica, e, processo para preparar compostos
EP1408976B3 (de)	2001-07-20	2010-08-25	Psychogenics Inc.	Behandlung von hyperaktivitätsstörungen und aufmerksamkeitsdefiziten
SE0301794D0 (sv) *	2003-06-19	2003-06-19	Astrazeneca Ab	New use III
SE0301798D0 (sv) *	2003-06-19	2003-06-19	Astrazeneca Ab	New use IV
AU2005318550B2 (en) *	2004-12-21	2011-04-07	F. Hoffmann-La Roche Ag	Tetralin and indane derivatives and uses thereof
EP1999121A1 (de) *	2006-03-17	2008-12-10	AstraZeneca AB	Neue tetraline als 5-ht6-modulatoren
SA08290245B1 (ar)	2007-04-23	2012-02-12	استرازينيكا ايه بي	مشتقات كربو كساميد جديدة من -n (8-اريل رباعي هيدرو نفثالين غير متجانس- 2- يل) أو -n (5-اريل كرومان غير متجانس -3-يل) لعلاج الألم
WO2008130319A2 (en) *	2007-04-23	2008-10-30	Astrazeneca Ab	Novel n-tetrahydronaphtalene or n-chromane carboxamide derivatives for the treatment of pain
WO2008130323A1 (en) *	2007-04-23	2008-10-30	Astrazeneca Ab	Novel 8-piperazine-tetrahydronaphtalene derivatives for the treatment of pain
WO2008130321A2 (en) *	2007-04-23	2008-10-30	Astrazeneca Ab	Novel n-tetrahydronaphtalene or 5-heterocyclyl-chromane or 8-heterocyclyl-tetrahydronaphtalene derivatives for the treatment of pain
WO2008130322A1 (en) *	2007-04-23	2008-10-30	Astrazeneca Ab	Novel 5-heterocyclyl-chromane derivatives for the treatment of pain
EP2098511A1 (de)	2008-03-07	2009-09-09	Solvias AG	Verfahren zur Herstellung von Verbindungen mit einer Hydronaphtalinstruktur mit einem asymmetrisch substituierten Benzolring
EP3297979A4 (de) *	2015-05-19	2019-01-09	Northeastern University	Verbindungen und verfahren zur modulation von serotoninrezeptoren in der peripherie
WO2020183011A1 (en)	2019-03-14	2020-09-17	Institut Curie	Htr1d inhibitors and uses thereof in the treatment of cancer
CN118121595B (zh) *	2024-05-06	2024-08-16	广州市朝利良生物科技有限公司	化合物eh-p005j在制备促伤口愈合药物中的用途

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3919624A1 (de) *	1989-06-15	1990-12-20	Boehringer Ingelheim Kg	Neue 2,5-diaminotetraline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
EP0498590B1 (de) *	1991-02-08	1997-04-09	Eli Lilly And Company	Ringsubstituierte 2-Amino-1,2,3,4-tetrahydronaphthaline
GB9119920D0 (en) *	1991-09-18	1991-10-30	Glaxo Group Ltd	Chemical compounds
GB9119932D0 (en) *	1991-09-18	1991-10-30	Glaxo Group Ltd	Chemical compounds
EP0533268B1 (de) *	1991-09-18	2001-08-16	Glaxo Group Limited	Benzanilidderivate als 5-HT1D-Antagonisten
DK148392D0 (da) *	1992-12-09	1992-12-09	Lundbeck & Co As H	Heterocykliske forbindelser
GB2273930A (en) *	1992-12-30	1994-07-06	Glaxo Group Ltd	Benzanilide derivatives
CA2158457C (en) *	1993-03-16	2001-04-17	Bertrand Leo Chenard	Naphthalene derivatives
SE9301732D0 (sv) *	1993-05-18	1993-05-18	Haakan Wilhelm Wikstroem	New centrally acting 5-,6-,7-, and 8-substituted sulphone esters of n-monosubstituted 2-aminotetralins
WO1995011243A1 (en) *	1993-10-19	1995-04-27	Smithkline Beecham Plc	Benzanilide derivatives as 5ht-1d receptor antagonists
SE9702799D0 (sv) *	1997-07-25	1997-07-25	Astra Ab	New compounds
SE9703375D0 (sv) *	1997-09-18	1997-09-18	Astra Ab	A new combination
SE9703376D0 (sv) *	1997-09-18	1997-09-18	Astra Ab	A new combination
SE9703374D0 (sv) *	1997-09-18	1997-09-18	Astra Ab	A new combination

1996
- 1996-03-22 SE SE9601110A patent/SE9601110D0/xx unknown
1997
- 1997-03-10 ZA ZA9702056A patent/ZA972056B/xx unknown
- 1997-03-20 CN CN97194726A patent/CN1073101C/zh not_active Expired - Fee Related
- 1997-03-20 AU AU21865/97A patent/AU709856B2/en not_active Ceased
- 1997-03-20 CZ CZ983019A patent/CZ301998A3/cs unknown
- 1997-03-20 HU HU9902454A patent/HUP9902454A3/hu unknown
- 1997-03-20 US US08/836,004 patent/US6124283A/en not_active Expired - Fee Related
- 1997-03-20 AT AT97914727T patent/ATE231847T1/de not_active IP Right Cessation
- 1997-03-20 SK SK1188-98A patent/SK282359B6/sk unknown
- 1997-03-20 IL IL12607097A patent/IL126070A0/xx unknown
- 1997-03-20 TR TR1998/01868T patent/TR199801868T2/xx unknown
- 1997-03-20 KR KR1019980707506A patent/KR20000064751A/ko not_active Application Discontinuation
- 1997-03-20 EE EE9800300A patent/EE9800300A/xx unknown
- 1997-03-20 WO PCT/SE1997/000469 patent/WO1997034883A1/en not_active Application Discontinuation
- 1997-03-20 PL PL97329121A patent/PL329121A1/xx unknown
- 1997-03-20 IL IL14568197A patent/IL145681A0/xx unknown
- 1997-03-20 NZ NZ331613A patent/NZ331613A/xx unknown
- 1997-03-20 JP JP9533410A patent/JP2000506883A/ja not_active Ceased
- 1997-03-20 CA CA002247940A patent/CA2247940A1/en not_active Abandoned
- 1997-03-20 EP EP97914727A patent/EP0888319B1/de not_active Expired - Lifetime
- 1997-03-20 BR BR9708093A patent/BR9708093A/pt unknown
- 1997-03-20 DE DE69718771T patent/DE69718771T2/de not_active Expired - Fee Related
- 1997-03-21 ID IDP970931A patent/ID16298A/id unknown
- 1997-03-21 HR HR9601110-1A patent/HRP970166A2/xx not_active Application Discontinuation
- 1997-03-21 AR ARP970101163A patent/AR006360A1/es not_active Application Discontinuation
- 1997-12-02 AR ARP970105660A patent/AR010080A1/es unknown
1998
- 1998-09-09 IS IS4844A patent/IS4844A/is unknown
- 1998-09-21 NO NO19984385A patent/NO311803B1/no not_active IP Right Cessation
- 1998-09-22 YU YU40998A patent/YU40998A/sh unknown
2000
- 2000-08-31 US US09/653,427 patent/US6410530B1/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
AR010080A1 (es)	2000-05-17
BR9708093A (pt)	1999-07-27
DE69718771D1 (de)	2003-03-06
CA2247940A1 (en)	1997-09-25
EP0888319B1 (de)	2003-01-29
AU709856B2 (en)	1999-09-09
NZ331613A (en)	2000-03-27
EE9800300A (et)	1999-02-15
EP0888319A1 (de)	1999-01-07
NO984385L (no)	1998-11-23
SK282359B6 (sk)	2002-01-07
IL126070A0 (en)	1999-05-09
HUP9902454A3 (en)	2002-01-28
ID16298A (id)	1997-09-18
SE9601110D0 (sv)	1996-03-22
ZA972056B (en)	1997-09-22
ATE231847T1 (de)	2003-02-15
HUP9902454A2 (hu)	1999-11-29
US6124283A (en)	2000-09-26
JP2000506883A (ja)	2000-06-06
IS4844A (is)	1998-09-09
DE69718771T2 (de)	2003-10-23
TR199801868T2 (xx)	1998-12-21
AU2186597A (en)	1997-10-10
AR006360A1 (es)	1999-08-25
US6410530B1 (en)	2002-06-25
YU40998A (sh)	1999-09-27
KR20000064751A (ko)	2000-11-06
CN1219170A (zh)	1999-06-09
NO311803B1 (no)	2002-01-28
NO984385D0 (no)	1998-09-21
PL329121A1 (en)	1999-03-15
CN1073101C (zh)	2001-10-17
SK118898A3 (en)	1999-03-12
WO1997034883A1 (en)	1997-09-25
IL145681A0 (en)	2002-06-30
CZ301998A3 (cs)	1999-05-12

Publication	Publication Date	Title
IL127566A0 (en)	1999-10-28	Substituted 6,5-hetero- bicyclic derivatives
IL128049A0 (en)	1999-11-30	Substituted 6,6-hetero-bicyclic derivatives
HRP980404B1 (en)	2002-10-31	Substituted 1,2,3,4-tetrahydronaphthalene derivatives
GB2319250B (en)	1999-01-27	Derivatives of 6,8-Difluoro-7-Hydroxycoumarin
PL331602A1 (en)	1999-08-02	Pyrido- or pyrimido-substituted 6,6- or 6,7-bicyclic derivatives
IL141908A0 (en)	2002-03-10	1,4-benzodiazepine derivatives
HRP970166A2 (en)	1998-04-30	Substituted 1,2,3,4-tetrahydronaphthalene derivatives
HK1018216A1 (en)	1999-12-17	New 19-nor-pregnene derivatives.
HU9600871D0 (en)	1996-05-28	New 2,3-benzodiazepine derivatives
HU9700609D0 (en)	1997-05-28	1,25-dihydroxy-12,22,23-trisdehydro-cholecalciferol derivatives
PL330141A1 (en)	1999-04-26	Novel derivatives of 10,11-dihydro-10-oxo-5h-dibezyl(b,f)-azepin-5-carboxagmide
IL132162A (en)	2000-08-13	2,3-epoxypropionamide derivatives
IL132162A0 (en)	2001-03-19	2, 3-Epoxypropionamide derivatives
HUP9903369A3 (en)	2002-02-28	8(9)-dehydroestradiol derivatives
ZA965384B (en)	1997-01-24	4-Amino-5-oxy-2,6,6-trimethyl-2-cycloheptene compounds
SI0920429T1 (en)	2003-06-30	Substituted pyrido- or pyrimido-containing 6,6- or 6,7-bicyclic derivatives
HUP9903001A3 (en)	2000-06-28	Substituted pyrido- or pyrimido-containing 6,6- or 6,7-bicyclic derivatives
IL119853A0 (en)	1997-03-18	Aminoindan derivatives

Legal Events

Date	Code	Title
1998-04-30	A1OB	Publication of a patent application
1998-10-30	AIPI	Request for the grant of a patent on the basis of a substantive examination of a patent application
2002-10-24	ODBC	Application rejected