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HRP20050735A2 - Dihydropteridinones, method for the production and use thereof in the form of drugs - Google Patents

Dihydropteridinones, method for the production and use thereof in the form of drugs

Info

Publication number
HRP20050735A2
HRP20050735A2 HR20050735A HRP20050735A HRP20050735A2 HR P20050735 A2 HRP20050735 A2 HR P20050735A2 HR 20050735 A HR20050735 A HR 20050735A HR P20050735 A HRP20050735 A HR P20050735A HR P20050735 A2 HRP20050735 A2 HR P20050735A2
Authority
HR
Croatia
Prior art keywords
dihydropteridinones
drugs
production
therefrom
groups
Prior art date
Application number
HR20050735A
Other languages
Croatian (hr)
Inventor
Hoffmann Matthias
Grauert Matthias
Brandl Trixi
Breitfelder Steffen
Eickmeier Christian
Steegmaier Martin
Schnapp Gisela
Baum Anke
Jens
Solca Flavio
Colbatzky Florian
Original Assignee
Boehringer Ingelheim Pharma Gmbh & Co.Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma Gmbh & Co.Kg filed Critical Boehringer Ingelheim Pharma Gmbh & Co.Kg
Publication of HRP20050735A2 publication Critical patent/HRP20050735A2/en
Publication of HRP20050735B1 publication Critical patent/HRP20050735B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Transplantation (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Izum se odnosi na nove dihidropteridinone s općomformulom (I)pri čemu skupine L i R1- R5 imaju značenje dano u patentnim zahtjevima i specifikaciji,izomere otud, proces za pripravu tih dihidropteridinona i upotrebu otud kao farmaceutskih pripravaka.The invention relates to novel dihydropteridinones of general formula (I) wherein the groups L and R 1 -R 5 have the meaning given in the claims and specification, the isomers therefrom, the process for the preparation of these dihydropteridinones and their use therefrom as pharmaceutical compositions.

HRP20050735AA 2003-02-26 2005-08-25 Dihydropteridinones, method for the production and use thereof in the form of drugs HRP20050735B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2003/001935 WO2004076454A1 (en) 2003-02-26 2003-02-26 Dihydropteridinones, method for the production and use thereof in the form of drugs

Publications (2)

Publication Number Publication Date
HRP20050735A2 true HRP20050735A2 (en) 2006-07-31
HRP20050735B1 HRP20050735B1 (en) 2013-08-31

Family

ID=32921552

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20050735AA HRP20050735B1 (en) 2003-02-26 2005-08-25 Dihydropteridinones, method for the production and use thereof in the form of drugs

Country Status (27)

Country Link
EP (1) EP1599478B1 (en)
JP (1) JP3876265B2 (en)
KR (1) KR100983462B1 (en)
CN (2) CN101200457A (en)
AT (1) ATE361924T1 (en)
AU (1) AU2003215591B2 (en)
BR (1) BR0318145A (en)
CA (1) CA2517020C (en)
CY (1) CY1106752T1 (en)
DE (1) DE50307267D1 (en)
DK (1) DK1599478T3 (en)
EA (1) EA008778B1 (en)
ES (1) ES2287583T3 (en)
HK (1) HK1089444A1 (en)
HR (1) HRP20050735B1 (en)
IL (1) IL170419A (en)
ME (1) ME00376B (en)
MX (1) MXPA05009068A (en)
NO (1) NO332538B1 (en)
NZ (1) NZ542498A (en)
PL (1) PL226417B1 (en)
PT (1) PT1599478E (en)
RS (1) RS52386B (en)
SI (1) SI1599478T1 (en)
TW (1) TWI313600B (en)
UA (1) UA80743C2 (en)
WO (1) WO2004076454A1 (en)

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