HRP20040909B1 - Pharmaceutical composition of a pde4 or a pde3/4 inhibitor and a histamine receptor antagonist - Google Patents

Pharmaceutical composition of a pde4 or a pde3/4 inhibitor and a histamine receptor antagonist

Info

Publication number: HRP20040909B1
Authority: HR; Croatia
Prior art keywords: pde3; pde4; inhibitor; pharmaceutical composition; receptor antagonist
Prior art date: 2002-03-06

Application number

Other languages

English (en)

Inventor

Christian Weimar

Daniela Bundschuh

Rolf Beume

Stefan-Lutz Wollin

Original Assignee

Altana Pharma Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-03-06

Filing date

2004-10-04

Publication date

2012-11-30

2004-10-04 Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag

2005-08-31 Publication of HRP20040909A2 publication Critical patent/HRP20040909A2/xx

2012-11-30 Publication of HRP20040909B1 publication Critical patent/HRP20040909B1/xx

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/423—Oxazoles condensed with carbocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4425—Pyridinium derivatives, e.g. pralidoxime, pyridostigmine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Otolaryngology (AREA)
Immunology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)

HR20040909 2002-03-06 2004-10-04 Pharmaceutical composition of a pde4 or a pde3/4 inhibitor and a histamine receptor antagonist HRP20040909B1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP02004987		2002-03-06
PCT/EP2003/001876 WO2003074055A1 (en)	2002-03-06	2003-02-25	Pharmaceutical composition of a pde4 or a pde3/4 inhibitor and a histamine receptor antagonist

Publications (2)

Publication Number	Publication Date
HRP20040909A2 HRP20040909A2 (en)	2005-08-31
HRP20040909B1 true HRP20040909B1 (en)	2012-11-30

Family

ID=27771841

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HR20040909 HRP20040909B1 (en)	2002-03-06	2004-10-04	Pharmaceutical composition of a pde4 or a pde3/4 inhibitor and a histamine receptor antagonist

Country Status (32)

Country	Link
US (1)	US20050112069A1 (pt)
EP (2)	EP1482938B1 (pt)
JP (1)	JP5150034B2 (pt)
KR (1)	KR20040095255A (pt)
CN (1)	CN101257904A (pt)
AR (1)	AR038858A1 (pt)
AT (1)	ATE369134T1 (pt)
AU (1)	AU2003212268B2 (pt)
BR (1)	BR0308220A (pt)
CA (1)	CA2478612C (pt)
CO (1)	CO5611148A2 (pt)
CY (2)	CY1106927T1 (pt)
DE (1)	DE60315426T2 (pt)
DK (2)	DK1849468T3 (pt)
EA (2)	EA007903B1 (pt)
ES (2)	ES2291618T3 (pt)
HK (1)	HK1071308A1 (pt)
HR (1)	HRP20040909B1 (pt)
IL (1)	IL163336A (pt)
IS (2)	IS2536B (pt)
MX (1)	MXPA04008460A (pt)
NO (1)	NO335254B1 (pt)
NZ (1)	NZ535611A (pt)
PL (1)	PL211574B1 (pt)
PT (2)	PT1849468E (pt)
RS (1)	RS51018B (pt)
SG (1)	SG160197A1 (pt)
SI (2)	SI1482938T1 (pt)
TW (1)	TWI347845B (pt)
UA (1)	UA80117C2 (pt)
WO (1)	WO2003074055A1 (pt)
ZA (1)	ZA200407104B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN101355876B (zh) *	2005-11-09	2012-09-05	康宾纳特克斯公司	一种适用于眼部给药的组合物
WO2008074803A2 (en) *	2006-12-20	2008-06-26	Glaxo Group Limited	4-benzyl-l ( 2h) -phthalazinones as h1 receptor antagonists
US20090182035A1 (en) *	2007-04-11	2009-07-16	Alcon Research, Ltd.	Use of a combination of olopatadine and cilomilast to treat non-infectious rhinitis and allergic conjunctivitis
RU2009141592A (ru) *	2007-04-11	2011-05-20	Алькон Рисерч, Лтд. (Us)	ПРИМЕНЕНИЕ ИНГИБИТОРА TNFα В СОЧЕТАНИИ С АНТИГИСТАМИННЫМ СРЕДСТВОМ ДЛЯ ЛЕЧЕНИЯ АЛЛЕРГИЧЕСКОГО РИНИТА И АЛЛЕРГИЧЕСКОГО КОНЪЮНКТИВИТА
US8877816B2 (en)	2007-11-21	2014-11-04	Decode Genetics Ehf	4-(or 5-) substituted catechol derivatives
KR20090061972A (ko) *	2007-12-12	2009-06-17	한미약품 주식회사	베포타스틴 ｐ-톨루엔술폰산염의 결정형, 이의 제조방법 및이를 포함하는 약학 조성물
CA2826183C (en)	2011-02-07	2019-05-14	Scipharm Sarl	Novel composition for the treatment of cystic fibrosis
KR102226833B1 (ko) *	2013-06-28	2021-03-12	한미약품 주식회사	레보세티리진 및 몬테루카스트를 포함하는 안정성이 개선된 복합 과립 제형
CA2993462A1 (en) *	2014-08-26	2016-03-03	Fundacion Para La Investigacion Medica Aplicada	Products for the treatment and prevention of neurological disorders coursing with a cognition deficit or impairment, and of neurodegenerative diseases
WO2016054971A1 (zh)	2014-10-09	2016-04-14	南京明德新药研发股份有限公司	羟基嘌呤类化合物及其应用
CN109956947A (zh) *	2017-12-25	2019-07-02	江苏恒瑞医药股份有限公司	一种cns抑制剂的新晶型、制备方法及用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2847693A1 (de) *	1978-11-03	1980-05-22	Hoechst Ag	Verfahren zur herstellung von pyrimido-(6,1-a)-isochinolin-2-onen
AU650953B2 (en)	1991-03-21	1994-07-07	Novartis Ag	Inhaler
ES2176252T3 (es) *	1993-07-02	2002-12-01	Altana Pharma Ag	Benzamidas sustituidas con fluoro-alcoxi y su utilizacion como agentes inhibidores de fosfodiesterasas de nucleotidos ciclicos.
US5900421A (en) *	1997-02-11	1999-05-04	Sepracor Inc.	Methods and compositions for treating allergic asthma and dermatitis using descarboethoxyloratadine
US5990147A (en) *	1997-11-07	1999-11-23	Schering Corporation	H3 receptor ligands of the phenyl-alkyl-imidazoles type
BR9804993A (pt) *	1998-11-10	2000-06-06	Panacea Biotec Ltd	Composição antialérgica e antiinflamatória
US6174878B1 (en) *	1999-08-31	2001-01-16	Alcon Laboratories, Inc.	Topical use of kappa opioid agonists to treat otic pain
EP1244654A1 (en) *	1999-10-25	2002-10-02	ALTANA Pharma AG	Tetrahydrothiopy ranphthalazinone derivatives as pde4 inhibitors
US7585847B2 (en) *	2000-02-03	2009-09-08	Coley Pharmaceutical Group, Inc.	Immunostimulatory nucleic acids for the treatment of asthma and allergy
GB0115181D0 (en) *	2001-06-20	2001-08-15	Glaxo Group Ltd	Novel use

2003
- 2003-02-20 TW TW092103525A patent/TWI347845B/zh not_active IP Right Cessation
- 2003-02-25 DK DK07112823.5T patent/DK1849468T3/da active
- 2003-02-25 JP JP2003572572A patent/JP5150034B2/ja not_active Expired - Fee Related
- 2003-02-25 EA EA200401137A patent/EA007903B1/ru not_active IP Right Cessation
- 2003-02-25 BR BR0308220-2A patent/BR0308220A/pt not_active Application Discontinuation
- 2003-02-25 WO PCT/EP2003/001876 patent/WO2003074055A1/en active IP Right Grant
- 2003-02-25 AT AT03708130T patent/ATE369134T1/de active
- 2003-02-25 ES ES03708130T patent/ES2291618T3/es not_active Expired - Lifetime
- 2003-02-25 SI SI200330970T patent/SI1482938T1/sl unknown
- 2003-02-25 SI SI200332245T patent/SI1849468T1/sl unknown
- 2003-02-25 EA EA200601592A patent/EA010886B1/ru not_active IP Right Cessation
- 2003-02-25 RS YUP-780/04A patent/RS51018B/sr unknown
- 2003-02-25 CA CA2478612A patent/CA2478612C/en not_active Expired - Fee Related
- 2003-02-25 KR KR10-2004-7013742A patent/KR20040095255A/ko not_active Application Discontinuation
- 2003-02-25 EP EP03708130A patent/EP1482938B1/en not_active Expired - Lifetime
- 2003-02-25 PT PT71128235T patent/PT1849468E/pt unknown
- 2003-02-25 ES ES07112823T patent/ES2400670T3/es not_active Expired - Lifetime
- 2003-02-25 MX MXPA04008460A patent/MXPA04008460A/es active IP Right Grant
- 2003-02-25 UA UA20041008055A patent/UA80117C2/uk unknown
- 2003-02-25 AU AU2003212268A patent/AU2003212268B2/en not_active Ceased
- 2003-02-25 SG SG200606154-3A patent/SG160197A1/en unknown
- 2003-02-25 CN CNA038053349A patent/CN101257904A/zh active Pending
- 2003-02-25 EP EP07112823A patent/EP1849468B1/en not_active Expired - Lifetime
- 2003-02-25 US US10/506,875 patent/US20050112069A1/en not_active Abandoned
- 2003-02-25 NZ NZ535611A patent/NZ535611A/xx not_active IP Right Cessation
- 2003-02-25 PL PL371056A patent/PL211574B1/pl unknown
- 2003-02-25 DK DK03708130T patent/DK1482938T3/da active
- 2003-02-25 DE DE60315426T patent/DE60315426T2/de not_active Expired - Lifetime
- 2003-02-25 PT PT03708130T patent/PT1482938E/pt unknown
- 2003-02-27 AR ARP030100646A patent/AR038858A1/es unknown
2004
- 2004-08-03 IL IL163336A patent/IL163336A/en not_active IP Right Cessation
- 2004-09-03 IS IS7438A patent/IS2536B/is unknown
- 2004-09-03 CO CO04086713A patent/CO5611148A2/es active IP Right Grant
- 2004-09-06 ZA ZA200407104A patent/ZA200407104B/en unknown
- 2004-10-04 HR HR20040909 patent/HRP20040909B1/xx not_active IP Right Cessation
- 2004-10-06 NO NO20044230A patent/NO335254B1/no not_active IP Right Cessation
2005
- 2005-05-20 HK HK05104255A patent/HK1071308A1/xx not_active IP Right Cessation
2007
- 2007-10-11 CY CY20071101307T patent/CY1106927T1/el unknown
2008
- 2008-09-04 IS IS8760A patent/IS8760A/is unknown
2013
- 2013-02-21 CY CY20131100163T patent/CY1113894T1/el unknown

Also Published As

Publication number	Publication date
EP1849468A3 (en)	2007-11-07
JP2005524666A (ja)	2005-08-18
SI1482938T1 (sl)	2007-12-31
ES2291618T3 (es)	2008-03-01
EP1849468A2 (en)	2007-10-31
SG160197A1 (en)	2010-04-29
EA200401137A1 (ru)	2005-04-28
AU2003212268B2 (en)	2008-09-11
CN101257904A (zh)	2008-09-03
HRP20040909A2 (en)	2005-08-31
IS7438A (is)	2004-09-03
PL371056A1 (en)	2005-06-13
TW200306855A (en)	2003-12-01
CA2478612C (en)	2013-12-10
DK1849468T3 (da)	2013-02-04
IS2536B (is)	2009-08-15
JP5150034B2 (ja)	2013-02-20
AU2003212268A1 (en)	2003-09-16
ATE369134T1 (de)	2007-08-15
CY1106927T1 (el)	2012-09-26
EP1849468B1 (en)	2012-12-05
ES2400670T3 (es)	2013-04-11
NZ535611A (en)	2006-03-31
CY1113894T1 (el)	2016-07-27
ZA200407104B (en)	2006-12-27
PT1849468E (pt)	2013-02-27
NO20044230L (no)	2004-12-06
EA007903B1 (ru)	2007-02-27
RS51018B (sr)	2010-10-31
US20050112069A1 (en)	2005-05-26
CA2478612A1 (en)	2003-09-12
UA80117C2 (uk)	2007-08-27
PL211574B1 (pl)	2012-05-31
IL163336A (en)	2009-02-11
BR0308220A (pt)	2005-01-04
MXPA04008460A (es)	2004-12-06
EP1482938A1 (en)	2004-12-08
DK1482938T3 (da)	2007-12-03
EA010886B1 (ru)	2008-12-30
PT1482938E (pt)	2007-11-15
RS78004A (en)	2006-12-15
WO2003074055A1 (en)	2003-09-12
EA200601592A1 (ru)	2006-12-29
KR20040095255A (ko)	2004-11-12
TWI347845B (en)	2011-09-01
SI1849468T1 (sl)	2013-03-29
NO335254B1 (no)	2014-10-27
CO5611148A2 (es)	2006-02-28
EP1482938B1 (en)	2007-08-08
HK1071308A1 (en)	2005-07-15
IS8760A (is)	2008-09-04
DE60315426T2 (de)	2008-07-03
AR038858A1 (es)	2005-01-26
DE60315426D1 (de)	2007-09-20

Publication	Publication Date	Title
IS8760A (is)	2008-09-04	Lyfjablanda úr pde4 eða pde3/4 tálma og histamínviðtakamótlyfi
IL159588A0 (en)	2004-06-01	Combination of an aldosterone receptor antagonist and an hmg coa reductase inhibitor
HUP0302615A3 (en)	2008-03-28	Kinase inhibitor quinazoline derivatives and pharmaceutical compositions containing them and their use
AU2003252478A1 (en)	2004-02-02	Ccr4 antagonist and medicinal use thereof
PL374878A1 (en)	2005-11-14	Use of cetp inhibitors and optionally hmg coa reductable inhibitors and/or antihypertensive agents
ZA200501381B (en)	2006-11-29	New spirocondensed quinazolinones and their use as phosphodiesterase inhibitors
HUP0400475A3 (en)	2006-02-28	Pharmaceutical compositions containing combination of at least two compounds selected from an at1-receptor antagonist or an ace inhibitor or a hmg-co-a reductase inhibitor groups and use thereof
AU2002231570A1 (en)	2002-08-06	Pharmaceutical compositions containing a cox-ii inhibitor and a muscle relaxant
IL153645A0 (en)	2003-07-06	Carboxamide compounds and their use as antagonists of a human 11cby receptor
HUP0303193A3 (en)	2007-08-28	Phthalayinone-piperidino-derivatives as pde4 inhibitors and pharmaceutical compositions containing them
IL205407A0 (en)	2011-07-31	Hyaluronic acid antagonist and inhibitor compositions and uses thereof
IL159538A0 (en)	2004-06-01	8/17 heterocyclic compounds and uses thereof as d-alanyl-d-alanine ligase inhibitors
AP2003002719A0 (en)	2003-06-30	Use of cox-2 inhibitors for preventing immunodeficiency
HUP0400654A3 (en)	2011-07-28	Substituted 8-arylquinoline phosphodiesterase 4 inhibitors and pharmaceutical compositions containing them
IL159040A0 (en)	2004-05-12	A pharmaceutical composition comprising a nicotinic receptor partial antagonist and an antiemetic agent of modulating cholinergic function
AU2002227123A1 (en)	2002-05-21	Method of treatment with a combination of a pde4 inhibitor and a leukotriene antagonist
HUP0500078A3 (en)	2010-07-28	Pharmaceutical composition containing a combination of a pde inhibitor and a leukotriene receptor antagonist
PL373032A1 (en)	2005-08-08	Combination of an aldosterone receptor antagonist and nicotinic acid or a nicotinic acid derivative
PL369736A1 (en)	2005-05-02	New medicinal compositions on the basis of anticholinergic agents and egfr kinase inhibitors
AU2003206014A8 (en)	2003-09-09	Neuropeptide receptor and uses thereof
IL148292A0 (en)	2002-09-12	Pharmaceutical compositions of halofuginone and other quinazolinone derivatives
AU2002339817A1 (en)	2003-04-28	Use of inhibitors of the y2 receptor of neuropeptide y in the treatment of alcoholism
HK1077230A1 (en)	2006-02-10	Medicinal composition hmg-coa reductase inhibitor
AU2002354760A1 (en)	2003-01-21	Glucocorticoid-induced receptor and methods of use
AU2002322290A1 (en)	2003-01-08	Vitamin d receptor antagonists and related compositions and methods of use

Legal Events

Date	Code	Title	Description
2005-08-31	A1OB	Publication of a patent application
2006-02-14	ARAI	Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
2007-11-27	PNAN	Change of the applicant name, address/residence	Owner name: NYCOMED GMBH, DE
2012-11-30	B1PR	Patent granted
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