HRP20010856A2 - Mutual prodrugs of amlodipine and atorvastatin - Google Patents
Mutual prodrugs of amlodipine and atorvastatin Download PDFInfo
- Publication number
- HRP20010856A2 HRP20010856A2 HR20010856A HRP20010856A HRP20010856A2 HR P20010856 A2 HRP20010856 A2 HR P20010856A2 HR 20010856 A HR20010856 A HR 20010856A HR P20010856 A HRP20010856 A HR P20010856A HR P20010856 A2 HRP20010856 A2 HR P20010856A2
- Authority
- HR
- Croatia
- Prior art keywords
- mammal
- pharmaceutically acceptable
- acceptable salt
- amount
- amlodipine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/55—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being also a pharmacologically or therapeutically active agent, i.e. the entire conjugate being a codrug, i.e. a dimer, oligomer or polymer of pharmacologically or therapeutically active compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13660899P | 1999-05-27 | 1999-05-27 | |
PCT/IB2000/000313 WO2000073298A1 (en) | 1999-05-27 | 2000-03-20 | Mutual prodrugs of amlodipine and atorvastatin |
Publications (1)
Publication Number | Publication Date |
---|---|
HRP20010856A2 true HRP20010856A2 (en) | 2002-12-31 |
Family
ID=22473579
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HR20010856A HRP20010856A2 (en) | 1999-05-27 | 2000-03-20 | Mutual prodrugs of amlodipine and atorvastatin |
Country Status (41)
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GT199800127A (es) * | 1997-08-29 | 2000-02-01 | Combinaciones terapeuticas. | |
US6737430B2 (en) | 2000-11-09 | 2004-05-18 | Pfizer, Inc. | Mutual prodrug of amlodipine and atorvastatin |
GB0027410D0 (en) * | 2000-11-09 | 2000-12-27 | Pfizer Ltd | Mutual prodrug of amlodipine and atorvastatin |
CA2449729C (en) * | 2001-06-11 | 2009-11-03 | Xenoport, Inc. | Prodrugs of gaba analogs, compositions and uses thereof |
US7232924B2 (en) | 2001-06-11 | 2007-06-19 | Xenoport, Inc. | Methods for synthesis of acyloxyalkyl derivatives of GABA analogs |
US7186855B2 (en) | 2001-06-11 | 2007-03-06 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
US6818787B2 (en) | 2001-06-11 | 2004-11-16 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
US8048917B2 (en) | 2005-04-06 | 2011-11-01 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
DE10140421A1 (de) * | 2001-08-17 | 2003-03-06 | Bayer Ag | Neue Kombination |
US7670612B2 (en) | 2002-04-10 | 2010-03-02 | Innercap Technologies, Inc. | Multi-phase, multi-compartment capsular delivery apparatus and methods for using same |
US20040053842A1 (en) * | 2002-07-02 | 2004-03-18 | Pfizer Inc. | Methods of treatment with CETP inhibitors and antihypertensive agents |
US7071210B2 (en) * | 2002-07-02 | 2006-07-04 | Pfizer Inc. | CETP inhibitors in combination with antihypertensive agents and uses thereof |
CN101068538A (zh) | 2004-11-04 | 2007-11-07 | 什诺波特有限公司 | 加巴喷丁前体药物持续释放口服剂型 |
EP1909848A2 (en) * | 2005-08-01 | 2008-04-16 | PSivida Inc. | HMGCoA REDUCTASE INHIBITOR CODRUGS AND USES THEREOF |
AR057882A1 (es) | 2005-11-09 | 2007-12-26 | Novartis Ag | Compuestos de accion doble de bloqueadores del receptor de angiotensina e inhibidores de endopeptidasa neutra |
US8354116B2 (en) * | 2007-06-18 | 2013-01-15 | Biochemics, Inc. | Bifunctional synthetic molecules |
JP4905738B2 (ja) | 2007-10-10 | 2012-03-28 | Nok株式会社 | アキュムレータ |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK161312C (da) | 1982-03-11 | 1991-12-09 | Pfizer | Analogifremgangsmaade til fremstilling af 2-aminoalkoxymethyl-4-phenyl-6-methyl-1,4-dihydropyridin-3,5-dicarboxylsyreestere eller syreadditionssalte deraf samt phthalimidoderivater til anvendelse som udgangsmateriale ved fremgangsmaaden |
GB8608335D0 (en) | 1986-04-04 | 1986-05-08 | Pfizer Ltd | Pharmaceutically acceptable salts |
US4681893A (en) | 1986-05-30 | 1987-07-21 | Warner-Lambert Company | Trans-6-[2-(3- or 4-carboxamido-substituted pyrrol-1-yl)alkyl]-4-hydroxypyran-2-one inhibitors of cholesterol synthesis |
FI94339C (fi) | 1989-07-21 | 1995-08-25 | Warner Lambert Co | Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi |
US5155120A (en) | 1991-01-14 | 1992-10-13 | Pfizer Inc | Method for treating congestive heart failure |
GT199800127A (es) * | 1997-08-29 | 2000-02-01 | Combinaciones terapeuticas. |
-
2000
- 2000-03-20 CN CN00808081A patent/CN1352640A/zh active Pending
- 2000-03-20 HU HU0201433A patent/HUP0201433A2/hu unknown
- 2000-03-20 ES ES00911145T patent/ES2220426T3/es not_active Expired - Lifetime
- 2000-03-20 HR HR20010856A patent/HRP20010856A2/hr not_active Application Discontinuation
- 2000-03-20 EA EA200101130A patent/EA200101130A1/ru unknown
- 2000-03-20 AU AU33139/00A patent/AU3313900A/en not_active Abandoned
- 2000-03-20 WO PCT/IB2000/000313 patent/WO2000073298A1/en active IP Right Grant
- 2000-03-20 IL IL14594700A patent/IL145947A0/xx unknown
- 2000-03-20 CA CA002375372A patent/CA2375372C/en not_active Expired - Fee Related
- 2000-03-20 BR BR0011006-0A patent/BR0011006A/pt not_active IP Right Cessation
- 2000-03-20 HK HK02107872.6A patent/HK1046282A1/zh unknown
- 2000-03-20 SK SK1679-2001A patent/SK16792001A3/sk unknown
- 2000-03-20 JP JP2000621364A patent/JP2003500487A/ja active Pending
- 2000-03-20 KR KR1020017015185A patent/KR20020012247A/ko not_active Ceased
- 2000-03-20 EP EP00911145A patent/EP1180102B9/en not_active Expired - Lifetime
- 2000-03-20 PL PL00353483A patent/PL353483A1/xx not_active Application Discontinuation
- 2000-03-20 CZ CZ20014229A patent/CZ20014229A3/cs unknown
- 2000-03-20 MX MXPA01012125A patent/MXPA01012125A/es active IP Right Grant
- 2000-03-20 TR TR2001/03391T patent/TR200103391T2/xx unknown
- 2000-03-20 DE DE60011424T patent/DE60011424T2/de not_active Expired - Fee Related
- 2000-03-20 EE EEP200100631A patent/EE200100631A/xx unknown
- 2000-03-20 AT AT00911145T patent/ATE268764T1/de not_active IP Right Cessation
- 2000-03-20 OA OA1200100312A patent/OA11950A/en unknown
- 2000-03-20 PT PT00911145T patent/PT1180102E/pt unknown
- 2000-03-20 DK DK00911145T patent/DK1180102T3/da active
- 2000-03-20 AP APAP/P/2001/002345A patent/AP2001002345A0/en unknown
- 2000-05-17 HN HN2000000075A patent/HN2000000075A/es unknown
- 2000-05-19 PA PA20008495701A patent/PA8495701A1/es unknown
- 2000-05-24 US US09/577,561 patent/US6486182B1/en not_active Expired - Fee Related
- 2000-05-24 TN TNTNSN00113A patent/TNSN00113A1/fr unknown
- 2000-05-24 CO CO00038315A patent/CO5170457A1/es not_active Application Discontinuation
- 2000-05-24 DZ DZ000092A patent/DZ3048A1/xx active
- 2000-05-24 MA MA25986A patent/MA26736A1/fr unknown
- 2000-05-25 PE PE2000000498A patent/PE20010169A1/es not_active Application Discontinuation
- 2000-05-25 GT GT200000078A patent/GT200000078A/es unknown
- 2000-05-25 SV SV2000000082A patent/SV2002000082A/es not_active Application Discontinuation
- 2000-05-26 AR ARP000102581A patent/AR022344A1/es not_active Application Discontinuation
-
2001
- 2001-10-30 IS IS6135A patent/IS6135A/is unknown
- 2001-11-26 ZA ZA200109691A patent/ZA200109691B/en unknown
- 2001-11-26 BG BG106149A patent/BG106149A/xx unknown
- 2001-11-26 NO NO20015756A patent/NO20015756L/no not_active Application Discontinuation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP1003503B1 (en) | Therapeutic combinations comprising amlodipin and atorvastatin | |
HRP20010857A2 (en) | Mutual salt of amlodipine and atorvastatin | |
NO323987B1 (no) | Farmasoytisk sammensetning og produkt omfattende atorvastatin, anvendelse derav, samt sett | |
HRP20010856A2 (en) | Mutual prodrugs of amlodipine and atorvastatin | |
AU2001247658A1 (en) | Combination of Carboxyalkylethers with Antihypertensive and Pharmaceutical use |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A1OB | Publication of a patent application | ||
OBST | Application withdrawn |