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HN1998000028A - Otropisomeros de 3 heteroaril - 4 (3h) - quinazolinonas. - Google Patents

Otropisomeros de 3 heteroaril - 4 (3h) - quinazolinonas.

Info

Publication number
HN1998000028A
HN1998000028A HN1998000028A HN1998000028A HN1998000028A HN 1998000028 A HN1998000028 A HN 1998000028A HN 1998000028 A HN1998000028 A HN 1998000028A HN 1998000028 A HN1998000028 A HN 1998000028A HN 1998000028 A HN1998000028 A HN 1998000028A
Authority
HN
Honduras
Prior art keywords
quinazolinonas
otropisomeros
heteroaril
aril
hetero
Prior art date
Application number
HN1998000028A
Other languages
English (en)
Inventor
Pfizer Products Inc
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of HN1998000028A publication Critical patent/HN1998000028A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A OTROPISOMEROS DE 3 HETEROARIL - 4 (3H) - QUINAZOLINONAS.
HN1998000028A 1997-02-28 1998-02-09 Otropisomeros de 3 heteroaril - 4 (3h) - quinazolinonas. HN1998000028A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3854097P 1997-02-28 1997-02-28

Publications (1)

Publication Number Publication Date
HN1998000028A true HN1998000028A (es) 1999-02-09

Family

ID=21900535

Family Applications (1)

Application Number Title Priority Date Filing Date
HN1998000028A HN1998000028A (es) 1997-02-28 1998-02-09 Otropisomeros de 3 heteroaril - 4 (3h) - quinazolinonas.

Country Status (40)

Country Link
US (1) US6380204B1 (es)
EP (1) EP0964860B1 (es)
JP (1) JP3299990B2 (es)
KR (1) KR20000075812A (es)
CN (1) CN1248254A (es)
AP (1) AP9801202A0 (es)
AR (1) AR011886A1 (es)
AT (1) ATE264854T1 (es)
AU (1) AU732448B2 (es)
BG (1) BG103687A (es)
BR (1) BR9807807A (es)
CA (1) CA2282279C (es)
CO (1) CO4950615A1 (es)
DE (1) DE69823339T2 (es)
DK (1) DK0964860T3 (es)
DZ (1) DZ2438A1 (es)
EA (1) EA001961B1 (es)
ES (1) ES2218801T3 (es)
GT (1) GT199800039A (es)
HN (1) HN1998000028A (es)
HR (1) HRP980108B1 (es)
HU (1) HUP0000935A3 (es)
ID (1) ID23435A (es)
IL (1) IL130897A0 (es)
IS (1) IS5141A (es)
MA (1) MA24485A1 (es)
NO (1) NO994178L (es)
NZ (1) NZ336627A (es)
OA (1) OA11088A (es)
PA (1) PA8446901A1 (es)
PE (1) PE57999A1 (es)
PL (1) PL335307A1 (es)
PT (1) PT964860E (es)
SK (1) SK113199A3 (es)
TN (1) TNSN98034A1 (es)
TR (1) TR199902094T2 (es)
TW (1) TW530055B (es)
UA (1) UA58536C2 (es)
WO (1) WO1998038187A1 (es)
ZA (1) ZA981665B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6323208B1 (en) 1997-09-05 2001-11-27 Pfizer Inc Atropisomers of 2,3-disubstituted-(5.6)-heteroaryl fused-pyrimidin-4-ones
JPH11279158A (ja) * 1998-02-09 1999-10-12 Pfizer Prod Inc キナゾリン―4―オン誘導体の製造方法
US6890930B1 (en) * 1999-09-28 2005-05-10 3-Dimensional Pharmaceuticals, Inc. Quinazolinones
MXPA06001552A (es) * 2003-08-08 2006-09-04 Ulysses Pharmaceutical Product Quinazolinil nitrofuranos halogenados como agentes antibacterianos.
US20080146562A1 (en) * 2003-08-08 2008-06-19 Ulysses Pharmaceutical Products Inc., Halogenated quinazolinyl nitrofurans as antibacterial agents
GB0416730D0 (en) 2004-07-27 2004-09-01 Novartis Ag Organic compounds
GB0507298D0 (en) 2005-04-11 2005-05-18 Novartis Ag Organic compounds
WO2007056124A2 (en) * 2005-11-04 2007-05-18 Hydra Biosciences, Inc. Compounds for modulating trpv3 function
MX2009003673A (es) * 2006-10-04 2009-04-22 Pfizer Prod Inc Derivados de piridido[4,3-d]pirimidin-4(3h)-ona como antagonistas de los receptores de calcio.
WO2008140750A1 (en) * 2007-05-10 2008-11-20 Hydra Biosciences Inc. Compounds for modulating trpv3 function
EP2411391A1 (en) * 2009-03-24 2012-02-01 Gilead Calistoga LLC Atropisomers of2-purinyl-3-tolyl-quinazolinone derivatives and methods of use
EP2435048B1 (en) * 2009-05-29 2019-07-03 Merck Sharp & Dohme Corp. Radiolabeled pde10 inhibitors
WO2013105985A1 (en) * 2011-02-28 2013-07-18 Philadelphia Health & Education Corporation Small molecule inhibitors of rad51 recombinase and methods thereof
CN115335050B (zh) 2020-01-29 2024-05-17 卡玛瑞制药有限公司 用于治疗皮肤病症的化合物和组合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1298603A (en) 1970-04-06 1972-12-06 Karamchand Premchand Private Quinazolinone derivatives
US4183931A (en) * 1977-09-08 1980-01-15 Research Corporation 2-Ketoalkyl-4(3H)-quinazolinones
WO1992013535A1 (en) * 1991-02-06 1992-08-20 Research Corporation Technologies, Inc. Anticonvulsant substituted quinazolones
ATE227293T1 (de) 1996-05-15 2002-11-15 Pfizer 2,3-disubstituierte-(5,6)-heteroarylkondensiert - pyrimidin-4-one
AU730503B2 (en) 1996-05-15 2001-03-08 Pfizer Inc. Novel 2,3 disubstituted-4(3H)-quinazolinones

Also Published As

Publication number Publication date
DZ2438A1 (fr) 2003-01-11
HUP0000935A3 (en) 2002-04-29
DE69823339T2 (de) 2005-05-12
EP0964860A1 (en) 1999-12-22
PA8446901A1 (es) 2000-05-24
PL335307A1 (en) 2000-04-10
SK113199A3 (en) 2001-10-08
CO4950615A1 (es) 2000-09-01
EA001961B1 (ru) 2001-10-22
BG103687A (en) 2000-06-30
AU5775998A (en) 1998-09-18
HRP980108A2 (en) 1998-12-31
PE57999A1 (es) 1999-06-21
ATE264854T1 (de) 2004-05-15
PT964860E (pt) 2004-07-30
CN1248254A (zh) 2000-03-22
ES2218801T3 (es) 2004-11-16
AP9801202A0 (en) 1999-08-26
DE69823339D1 (de) 2004-05-27
UA58536C2 (uk) 2003-08-15
ZA981665B (en) 1999-08-17
DK0964860T3 (da) 2004-07-26
TNSN98034A1 (fr) 2005-03-15
ID23435A (id) 2000-04-20
IS5141A (is) 1999-07-30
EP0964860B1 (en) 2004-04-21
TR199902094T2 (xx) 1999-12-21
OA11088A (en) 2002-03-15
BR9807807A (pt) 2000-02-22
JP2000509732A (ja) 2000-08-02
EA199900689A1 (ru) 2000-02-28
HUP0000935A2 (hu) 2001-04-28
NZ336627A (en) 2000-12-22
WO1998038187A1 (en) 1998-09-03
AR011886A1 (es) 2000-09-13
US6380204B1 (en) 2002-04-30
IL130897A0 (en) 2001-01-28
NO994178D0 (no) 1999-08-27
JP3299990B2 (ja) 2002-07-08
NO994178L (no) 1999-08-27
CA2282279A1 (en) 1998-09-03
GT199800039A (es) 1999-08-13
AU732448B2 (en) 2001-04-26
KR20000075812A (ko) 2000-12-26
TW530055B (en) 2003-05-01
MA24485A1 (fr) 1998-10-01
CA2282279C (en) 2004-11-02
HRP980108B1 (en) 2004-10-31

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