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HK82697A - 3-[2-(dimethylamino)ethyl]-N-methyl-1H-indole-5-methane-sulphonamide sulphate (2:1) - Google Patents

3-[2-(dimethylamino)ethyl]-N-methyl-1H-indole-5-methane-sulphonamide sulphate (2:1)

Info

Publication number
HK82697A
HK82697A HK82697A HK82697A HK82697A HK 82697 A HK82697 A HK 82697A HK 82697 A HK82697 A HK 82697A HK 82697 A HK82697 A HK 82697A HK 82697 A HK82697 A HK 82697A
Authority
HK
Hong Kong
Prior art keywords
sulphonamide
indole
sulphate
dimethylamino
methane
Prior art date
Application number
HK82697A
Other languages
English (en)
Inventor
Joanne Craig
Derek Leslie Crookes
Stephen John Skittrall
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of HK82697A publication Critical patent/HK82697A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16Tryptamines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Indole Compounds (AREA)
HK82697A 1990-12-12 1997-06-19 3-[2-(dimethylamino)ethyl]-N-methyl-1H-indole-5-methane-sulphonamide sulphate (2:1) HK82697A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909026998A GB9026998D0 (en) 1990-12-12 1990-12-12 Medicaments

Publications (1)

Publication Number Publication Date
HK82697A true HK82697A (en) 1997-06-27

Family

ID=10686904

Family Applications (1)

Application Number Title Priority Date Filing Date
HK82697A HK82697A (en) 1990-12-12 1997-06-19 3-[2-(dimethylamino)ethyl]-N-methyl-1H-indole-5-methane-sulphonamide sulphate (2:1)

Country Status (36)

Country Link
US (2) US5554639A (zh)
EP (1) EP0490689B1 (zh)
JP (1) JP2994037B2 (zh)
KR (1) KR100211479B1 (zh)
CN (2) CN1030890C (zh)
AP (1) AP230A (zh)
AT (1) ATE119881T1 (zh)
AU (1) AU650706B2 (zh)
BE (1) BE1005085A3 (zh)
CA (1) CA2098302C (zh)
CH (1) CH684192A5 (zh)
CY (1) CY2005A (zh)
CZ (1) CZ281931B6 (zh)
DE (1) DE69108200T2 (zh)
DK (1) DK0490689T3 (zh)
EG (1) EG20219A (zh)
ES (1) ES2069836T3 (zh)
FR (1) FR2670487B1 (zh)
GB (2) GB9026998D0 (zh)
GR (1) GR3015430T3 (zh)
HK (1) HK82697A (zh)
HU (1) HU211937A9 (zh)
IE (1) IE62894B1 (zh)
IL (1) IL100330A (zh)
IS (1) IS1706B (zh)
IT (1) IT1252868B (zh)
MX (1) MX9102501A (zh)
MY (1) MY109265A (zh)
NL (1) NL9102071A (zh)
NZ (1) NZ240942A (zh)
PT (1) PT99757B (zh)
RU (1) RU2108328C1 (zh)
TW (2) TW205035B (zh)
WO (1) WO1992010477A1 (zh)
YU (1) YU48926B (zh)
ZA (1) ZA919750B (zh)

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US6132757A (en) 1998-05-01 2000-10-17 Neal R. Cutler Treatment of sexual dysfunction in certain patient groups
US6426084B1 (en) 2000-06-19 2002-07-30 Neal R. Cutler Treatment of sexual dysfunction in certain patient groups
US6187790B1 (en) 1999-03-04 2001-02-13 Neal R. Cutler Use of cilostazol for treatment of sexual dysfunction
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US20040115133A1 (en) * 2000-05-10 2004-06-17 Wermeling Daniel P. Intranasal opioid compositions
US6610271B2 (en) * 2000-05-10 2003-08-26 University Of Kentucky Research Foundation System and method for intranasal administration of lorazepam
US6451813B1 (en) 2001-01-26 2002-09-17 R. T. Alamo Ventures I, Llc Treatment of gastroparesis in certain patient groups
US6562838B2 (en) 2001-01-26 2003-05-13 R. T. Alamo Ventures I, L.L.C. Treatment of cardiovascular disease with quinolinone enantiomers
US6458804B1 (en) 2001-01-26 2002-10-01 R.T. Alamo Venturesi, Llc Methods for the treatment of central nervous system disorders in certain patient groups
US20040176359A1 (en) * 2001-02-20 2004-09-09 University Of Kentucky Research Foundation Intranasal Benzodiazepine compositions
US20030096748A1 (en) * 2001-06-04 2003-05-22 The Regents Of The University Of Michigan Methods and compositions for the treatment of diseases associated with signal transduction aberrations
US8329734B2 (en) * 2009-07-27 2012-12-11 Afgin Pharma Llc Topical therapy for migraine
US20030013753A1 (en) * 2001-06-05 2003-01-16 Ronald Aung-Din Transdermal migraine therapy
US7041677B2 (en) * 2002-03-01 2006-05-09 R.T. Alamo Ventures I, Llc Use of monochloroflosequinan in the treatment of sexual dysfunction
US7208628B2 (en) * 2002-05-13 2007-04-24 Kansas State University Research Foundation Compositions and methods for the treatment of hepatitis C virus infection
US7074893B2 (en) * 2002-06-03 2006-07-11 Regents Of The University Of Michigan Methods and compositions for the treatment of diseases associated with signal transduction aberrations
US20040068000A1 (en) * 2002-10-02 2004-04-08 Mintong Guo Compression coated tablets
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US20080213363A1 (en) * 2003-01-23 2008-09-04 Singh Nikhilesh N Methods and compositions for delivering 5-HT3 antagonists across the oral mucosa
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US20070065463A1 (en) * 2003-06-20 2007-03-22 Ronald Aung-Din Topical therapy for the treatment of migranes, muscle sprains, muscle spasms, spasticity and related conditions
US20050089558A1 (en) * 2003-10-28 2005-04-28 Alamo Pharmaceuticals, Llc Compositions and methods for the co-formulation and administration of tramadol and propoxyphene
WO2005119607A2 (en) * 2004-06-03 2005-12-15 Tyfone, Inc. System and method for securing financial transactions
US20060002989A1 (en) * 2004-06-10 2006-01-05 Ahmed Salah U Formulations of sumatriptan for absorption across biological membranes, and methods of making and using the same
MY147767A (en) 2004-06-16 2013-01-31 Janssen Pharmaceutica Nv Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders
WO2006127184A1 (en) 2005-05-20 2006-11-30 Janssen Pharmaceutica N.V. Process for preparation of sulfamide derivatives
US20070166336A1 (en) * 2005-12-13 2007-07-19 David Delmarre Stable and palatable oral liquid sumatriptan compositions
US8716231B2 (en) 2005-12-19 2014-05-06 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for the treatment of pain
US8492431B2 (en) 2005-12-19 2013-07-23 Janssen Pharmaceutica, N.V. Use of benzo-fused heterocycle sulfamide derivatives for the treatment of obesity
US8691867B2 (en) 2005-12-19 2014-04-08 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for the treatment of substance abuse and addiction
US8497298B2 (en) 2005-12-19 2013-07-30 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for lowering lipids and lowering blood glucose levels
US8937096B2 (en) 2005-12-19 2015-01-20 Janssen Pharmaceutica Nv Use of benzo-fused heterocyle sulfamide derivatives for the treatment of mania and bipolar disorder
US20070191461A1 (en) * 2006-02-15 2007-08-16 Smith-Swintosky Virginia L Use of benzo-heteroaryl sulfamide derivatives for the treatment of migraine
JP2009537635A (ja) 2006-05-19 2009-10-29 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 癲癇の処置のための共同−療法
CA2665841C (en) 2006-10-09 2016-04-05 Charleston Laboratories, Inc. Pharmaceutical compositions
BRPI0715579A2 (pt) * 2006-10-19 2015-05-26 Auspex Pharmaceuticals Inc "composto, composição farmacêutica e uso de um composto"
US20080275030A1 (en) 2007-01-19 2008-11-06 Sveinbjorn Gizurarson Methods and Compositions for the Delivery of a Therapeutic Agent
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US20090252791A1 (en) * 2008-04-02 2009-10-08 Venkata Nookaraju Sreedharala Pharmaceutical compositions comprising a triptan and a nonsteroidal anti-inflammatory drug
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CA2767576C (en) 2009-07-08 2020-03-10 Charleston Laboratories Inc. Pharmaceutical compositions comprising an antiemetic and an opioid analgesic
US11337962B2 (en) 2009-09-25 2022-05-24 Upsher-Smith Laboratories, Llc Formulations comprising triptan compounds
NZ599344A (en) * 2009-09-25 2015-02-27 Reddy’S Lab Ltd Dr Formulations comprising triptan compounds
US10383816B2 (en) 2015-03-02 2019-08-20 Afgin Pharma, Llc Topical regional neuro-affective therapy with cannabinoid combination products
AU2016226267A1 (en) 2015-03-02 2017-09-28 Afgin Pharma, Llc Topical regional neuro-affective therapy with cannabinoids
ES2842523T3 (es) 2015-05-15 2021-07-14 Univ Michigan Regents Métodos y composiciones para el tratamiento de la artritis
CA3055170A1 (en) 2016-03-04 2017-09-08 Charleston Laboratories, Inc. Pharmaceutical compositions
US20180049994A1 (en) 2016-08-16 2018-02-22 Afgin Pharma, Llc Topical regional neuro-affective therapy with caryophyllene
EP3706744B1 (en) 2017-11-07 2022-08-17 The Regents of The University of Michigan Small molecule inhibitors of shared epitope-calreticulin interactions and methods of use
US20220096438A1 (en) 2018-09-07 2022-03-31 Upsher-Smith Laboratories, Llc Methods of treating migraine
US11364225B2 (en) * 2019-08-21 2022-06-21 Bn Intellectual Properties, Inc. Pharmaceutical formulation for treating symptoms of migraine and cluster headaches, and method of using the same
WO2021173936A1 (en) * 2020-02-27 2021-09-02 Biohaven Pharmaceutical Holding Company Ltd. Oral fast-dispersing dosage form of rimegepant

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GB2162522B (en) * 1984-08-01 1988-02-24 Glaxo Group Ltd An indole derivative
GB8615599D0 (en) * 1986-06-26 1986-07-30 Glaxo Group Ltd Chemical compounds
GB8928208D0 (en) * 1989-12-13 1990-02-14 Glaxo Group Ltd Medicaments

Also Published As

Publication number Publication date
YU191491A (sh) 1994-04-05
TW300886B (zh) 1997-03-21
EG20219A (en) 1997-11-30
EP0490689B1 (en) 1995-03-15
IL100330A (en) 1996-06-18
IE914317A1 (en) 1992-06-17
HU211937A9 (en) 1996-01-29
CN1050831C (zh) 2000-03-29
CZ114093A3 (en) 1994-02-16
DK0490689T3 (da) 1995-05-22
CN1063099A (zh) 1992-07-29
IS3790A7 (is) 1992-06-13
DE69108200T2 (de) 1995-07-20
WO1992010477A1 (en) 1992-06-25
IL100330A0 (en) 1992-09-06
NL9102071A (nl) 1992-07-01
RU2108328C1 (ru) 1998-04-10
EP0490689A1 (en) 1992-06-17
US5705520A (en) 1998-01-06
IT1252868B (it) 1995-06-28
ITRM910922A1 (it) 1993-06-11
NZ240942A (en) 1994-03-25
JP2994037B2 (ja) 1999-12-27
IE62894B1 (en) 1995-03-08
GB2251614A (en) 1992-07-15
ZA919750B (en) 1992-10-28
JPH06503560A (ja) 1994-04-21
AU650706B2 (en) 1994-06-30
PT99757B (pt) 1999-05-31
CN1128259A (zh) 1996-08-07
US5554639A (en) 1996-09-10
TW205035B (zh) 1993-05-01
MX9102501A (es) 1992-09-01
BE1005085A3 (fr) 1993-04-13
AP230A (en) 1993-01-27
FR2670487A1 (fr) 1992-06-19
GB2251614B (en) 1994-12-14
FR2670487B1 (fr) 1993-08-20
CN1030890C (zh) 1996-02-07
AP9100339A0 (en) 1992-01-31
CZ281931B6 (cs) 1997-04-16
ATE119881T1 (de) 1995-04-15
CA2098302A1 (en) 1992-06-13
PT99757A (pt) 1992-12-31
KR100211479B1 (ko) 1999-08-02
ITRM910922A0 (it) 1991-12-11
ES2069836T3 (es) 1995-05-16
GR3015430T3 (en) 1995-06-30
YU48926B (sh) 2002-12-10
DE69108200D1 (de) 1995-04-20
AU9072091A (en) 1992-07-08
CY2005A (en) 1997-12-05
MY109265A (en) 1996-12-31
IS1706B (is) 1998-12-10
CH684192A5 (fr) 1994-07-29
GB9026998D0 (en) 1991-01-30
CA2098302C (en) 2001-10-16
GB9126297D0 (en) 1992-02-12

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20091212