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HK18696A - Peptides having tachykinin antagonist activity a process for preparation thereof and pharmaceutical compositions comprising the same - Google Patents

Peptides having tachykinin antagonist activity a process for preparation thereof and pharmaceutical compositions comprising the same

Info

Publication number
HK18696A
HK18696A HK18696A HK18696A HK18696A HK 18696 A HK18696 A HK 18696A HK 18696 A HK18696 A HK 18696A HK 18696 A HK18696 A HK 18696A HK 18696 A HK18696 A HK 18696A
Authority
HK
Hong Kong
Prior art keywords
preparation
pharmaceutical compositions
peptides
same
antagonist activity
Prior art date
Application number
HK18696A
Other languages
English (en)
Inventor
Matsuo Masaaki
Hagiwara Daijiro
Miyake Hiroshi
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of HK18696A publication Critical patent/HK18696A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0821Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0202Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06139Dipeptides with the first amino acid being heterocyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Two-Way Televisions, Distribution Of Moving Picture Or The Like (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HK18696A 1989-12-22 1996-02-01 Peptides having tachykinin antagonist activity a process for preparation thereof and pharmaceutical compositions comprising the same HK18696A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898929070A GB8929070D0 (en) 1989-12-22 1989-12-22 Peptide compounds,processes for preparation thereof and pharmaceutical composition comprising the same

Publications (1)

Publication Number Publication Date
HK18696A true HK18696A (en) 1996-02-09

Family

ID=10668423

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18696A HK18696A (en) 1989-12-22 1996-02-01 Peptides having tachykinin antagonist activity a process for preparation thereof and pharmaceutical compositions comprising the same

Country Status (21)

Country Link
US (1) US5468731A (xx)
EP (1) EP0443132B1 (xx)
JP (1) JP2560919B2 (xx)
KR (1) KR0180223B1 (xx)
CN (2) CN1034869C (xx)
AT (1) ATE98651T1 (xx)
AU (1) AU640185B2 (xx)
CA (1) CA2032864C (xx)
DE (1) DE69005286T2 (xx)
DK (1) DK0443132T3 (xx)
ES (1) ES2060910T3 (xx)
FI (1) FI93548C (xx)
GB (1) GB8929070D0 (xx)
HK (1) HK18696A (xx)
HU (2) HUT56581A (xx)
IE (1) IE64570B1 (xx)
NO (1) NO177535C (xx)
PT (1) PT96324B (xx)
RU (1) RU2055078C1 (xx)
UA (1) UA27254C2 (xx)
ZA (1) ZA909901B (xx)

Families Citing this family (88)

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US5420297A (en) * 1990-10-24 1995-05-30 Fujisawa Pharmaceutical Co., Ltd. Peptides having substance P antagonistic activity
US5610140A (en) * 1991-04-01 1997-03-11 Cortech, Inc. Bradykinin receptor antagonists with neurokinin receptor blocking activity
US5472978A (en) * 1991-07-05 1995-12-05 Merck Sharp & Dohme Ltd. Aromatic compounds, pharmaceutical compositions containing them and their use in therapy
US5654400A (en) * 1991-10-04 1997-08-05 Fujisawa Pharmaceutical Co., Ltd. Process for making peptide compounds having tachykinin antagonistic activity
HUT70741A (en) * 1991-11-12 1995-10-30 Pfizer Acyclic ethylenediamine derivatives as substance p receptor antagonists
GB9200535D0 (en) * 1992-01-10 1992-02-26 Fujisawa Pharmaceutical Co New compound
ES2153841T3 (es) * 1992-08-13 2001-03-16 Warner Lambert Co Antagonistas de la taciquinina.
DK0610487T3 (da) * 1992-09-03 2000-05-15 Boehringer Ingelheim Pharma Nye aminosyrederivater, fremgangsmåde til deres fremstilling og farmaceutiske præparater indeholdende disse forbindelser
DE4243496A1 (de) * 1992-09-03 1994-03-10 Boehringer Ingelheim Kg Neue Dipeptidderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen
FR2700472B1 (fr) 1993-01-19 1995-02-17 Rhone Poulenc Rorer Sa Association synergisante ayant un effet antagoniste des récepteurs NK1 et NK2.
WO1994020126A1 (en) * 1993-03-03 1994-09-15 Fujisawa Pharmaceutical Co., Ltd. Use of peptides for the manufacture of a medicament
WO1995000536A1 (en) * 1993-06-22 1995-01-05 Fujisawa Pharmaceutical Co., Ltd. Peptide compounds
EP0719561A4 (en) * 1993-08-10 1997-07-30 Fujisawa Pharmaceutical Co Percutaneous absorbent preparation
WO1995011699A1 (en) * 1993-10-29 1995-05-04 The Trustees Of Boston University Physiologically stable compositions of butyric acid, and butyric acid salts and derivatives as anti-neoplastic agents
US6403577B1 (en) 1993-11-17 2002-06-11 Eli Lilly And Company Hexamethyleneiminyl tachykinin receptor antagonists
ITFI940009A1 (it) * 1994-01-19 1995-07-19 Menarini Farma Ind Antagonisti delle tachichinine, loro preparazione e formulazioni farmaceutiche che li contengono.
US5837687A (en) * 1994-03-17 1998-11-17 Fujirebio Inc. Azapeptide derivative
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NZ285750A (en) * 1994-05-07 1998-08-26 Boehringer Ingelheim Int Neurokinin (tachykinin) antagonists
FR2728166A1 (fr) 1994-12-19 1996-06-21 Oreal Composition topique contenant un antagoniste de substance p
FR2728169A1 (fr) 1994-12-19 1996-06-21 Oreal Utilisation d'un antagoniste de substance p pour le traitement des prurits et des dysesthesies oculaires ou palpebrales
FR2728165A1 (fr) 1994-12-19 1996-06-21 Oreal Utilisation d'un antagoniste de substance p pour le traitement des rougeurs cutanees d'origine neurogene
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US4223020A (en) * 1979-03-30 1980-09-16 Beckman Instruments, Inc. Synthetic peptides having pituitary growth hormone releasing activity
US4395401A (en) * 1981-09-09 1983-07-26 Smithkline Beckman Corporation Renally active dipeptides
US5187156A (en) * 1988-03-16 1993-02-16 Fujisawa Pharmaceutical Co., Ltd. Peptide compounds, processes for preparation thereof and pharmaceutical composition comprising the same
DE3818850A1 (de) * 1988-06-03 1989-12-07 Hoechst Ag Oligopeptide mit zyklischen prolin-analogen aminosaeuren
DE3913272A1 (de) * 1989-04-22 1990-10-25 Hoechst Ag Dipeptid-derivate mit enzym-inhibitorischer wirkung
DE3913290A1 (de) * 1989-04-22 1990-10-25 Hoechst Ag Renin-hemmende di- und tripeptide, verfahren zu deren herstellung, diese enthaltende mittel und ihre verwendung
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Also Published As

Publication number Publication date
EP0443132B1 (en) 1993-12-15
AU640185B2 (en) 1993-08-19
HU908443D0 (en) 1991-07-29
DK0443132T3 (da) 1994-01-24
ES2060910T3 (es) 1994-12-01
CN1034869C (zh) 1997-05-14
US5468731A (en) 1995-11-21
DE69005286T2 (de) 1994-04-21
PT96324B (pt) 1998-10-30
CA2032864C (en) 2003-05-06
FI93548C (fi) 1995-04-25
HUT56581A (en) 1991-09-30
PT96324A (pt) 1991-09-30
FI93548B (fi) 1995-01-13
JP2560919B2 (ja) 1996-12-04
KR0180223B1 (ko) 1999-04-01
NO177535C (no) 1995-10-04
CN1064080A (zh) 1992-09-02
NO177535B (no) 1995-06-26
EP0443132A1 (en) 1991-08-28
ZA909901B (en) 1991-10-30
JPH04210996A (ja) 1992-08-03
UA27254C2 (uk) 2000-08-15
CA2032864A1 (en) 1991-06-23
RU2055078C1 (ru) 1996-02-27
NO905572L (no) 1991-06-24
IE904581A1 (en) 1991-07-03
IE64570B1 (en) 1995-08-23
ATE98651T1 (de) 1994-01-15
AU6801090A (en) 1991-06-27
CN1159949A (zh) 1997-09-24
DE69005286D1 (de) 1994-01-27
GB8929070D0 (en) 1990-02-28
HU211558A9 (en) 1995-12-28
KR910011891A (ko) 1991-08-07
FI906204A0 (fi) 1990-12-17
NO905572D0 (no) 1990-12-21
FI906204A (fi) 1991-06-23

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20041212