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HK1217921A1 - 血泵系統以及方法 - Google Patents

血泵系統以及方法

Info

Publication number
HK1217921A1
HK1217921A1 HK16105952.7A HK16105952A HK1217921A1 HK 1217921 A1 HK1217921 A1 HK 1217921A1 HK 16105952 A HK16105952 A HK 16105952A HK 1217921 A1 HK1217921 A1 HK 1217921A1
Authority
HK
Hong Kong
Prior art keywords
methods
blood pump
pump systems
systems
blood
Prior art date
Application number
HK16105952.7A
Other languages
English (en)
Inventor
F Nicholas Franano
Ii Howard M Loree
Geoff Tansley
Steve Woodard
Barrett Hutto
Original Assignee
Flow Forward Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2012/050978 external-priority patent/WO2013025821A2/en
Priority claimed from PCT/US2012/050983 external-priority patent/WO2013025826A1/en
Application filed by Flow Forward Medical Inc filed Critical Flow Forward Medical Inc
Publication of HK1217921A1 publication Critical patent/HK1217921A1/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3653Interfaces between patient blood circulation and extra-corporal blood circuit
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/20Type thereof
    • A61M60/205Non-positive displacement blood pumps
    • A61M60/216Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
    • A61M60/226Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller the blood flow through the rotating member having mainly radial components
    • A61M60/232Centrifugal pumps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3653Interfaces between patient blood circulation and extra-corporal blood circuit
    • A61M1/3655Arterio-venous shunts or fistulae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3653Interfaces between patient blood circulation and extra-corporal blood circuit
    • A61M1/3659Cannulae pertaining to extracorporeal circulation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10Location thereof with respect to the patient's body
    • A61M60/104Extracorporeal pumps, i.e. the blood being pumped outside the patient's body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10Location thereof with respect to the patient's body
    • A61M60/104Extracorporeal pumps, i.e. the blood being pumped outside the patient's body
    • A61M60/117Extracorporeal pumps, i.e. the blood being pumped outside the patient's body for assisting the heart, e.g. transcutaneous or external ventricular assist devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10Location thereof with respect to the patient's body
    • A61M60/122Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10Location thereof with respect to the patient's body
    • A61M60/122Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
    • A61M60/126Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel
    • A61M60/152Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel branching on and drawing blood from a blood vessel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/40Details relating to driving
    • A61M60/403Details relating to driving for non-positive displacement blood pumps
    • A61M60/419Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being permanent magnetic, e.g. from a rotating magnetic coupling between driving and driven magnets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/40Details relating to driving
    • A61M60/403Details relating to driving for non-positive displacement blood pumps
    • A61M60/422Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being electromagnetic, e.g. using canned motor pumps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/50Details relating to control
    • A61M60/508Electronic control means, e.g. for feedback regulation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/50Details relating to control
    • A61M60/508Electronic control means, e.g. for feedback regulation
    • A61M60/538Regulation using real-time blood pump operational parameter data, e.g. motor current
    • A61M60/546Regulation using real-time blood pump operational parameter data, e.g. motor current of blood flow, e.g. by adapting rotor speed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/50Details relating to control
    • A61M60/508Electronic control means, e.g. for feedback regulation
    • A61M60/538Regulation using real-time blood pump operational parameter data, e.g. motor current
    • A61M60/554Regulation using real-time blood pump operational parameter data, e.g. motor current of blood pressure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80Constructional details other than related to driving
    • A61M60/802Constructional details other than related to driving of non-positive displacement blood pumps
    • A61M60/81Pump housings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80Constructional details other than related to driving
    • A61M60/802Constructional details other than related to driving of non-positive displacement blood pumps
    • A61M60/81Pump housings
    • A61M60/816Sensors arranged on or in the housing, e.g. ultrasound flow sensors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80Constructional details other than related to driving
    • A61M60/802Constructional details other than related to driving of non-positive displacement blood pumps
    • A61M60/818Bearings
    • A61M60/82Magnetic bearings
    • A61M60/822Magnetic bearings specially adapted for being actively controlled
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80Constructional details other than related to driving
    • A61M60/802Constructional details other than related to driving of non-positive displacement blood pumps
    • A61M60/818Bearings
    • A61M60/824Hydrodynamic or fluid film bearings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80Constructional details other than related to driving
    • A61M60/802Constructional details other than related to driving of non-positive displacement blood pumps
    • A61M60/818Bearings
    • A61M60/825Contact bearings, e.g. ball-and-cup or pivot bearings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80Constructional details other than related to driving
    • A61M60/855Constructional details other than related to driving of implantable pumps or pumping devices
    • A61M60/865Devices for guiding or inserting pumps or pumping devices into the patient's body
    • A61M60/867Devices for guiding or inserting pumps or pumping devices into the patient's body using position detection during deployment, e.g. for blood pumps mounted on and driven through a catheter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/32General characteristics of the apparatus with radio-opaque indicia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3331Pressure; Flow
    • A61M2205/3334Measuring or controlling the flow rate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3331Pressure; Flow
    • A61M2205/3344Measuring or controlling pressure at the body treatment site

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Anesthesiology (AREA)
  • Mechanical Engineering (AREA)
  • Vascular Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • External Artificial Organs (AREA)
  • Structures Of Non-Positive Displacement Pumps (AREA)
HK16105952.7A 2012-08-15 2016-05-25 血泵系統以及方法 HK1217921A1 (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
PCT/US2012/050978 WO2013025821A2 (en) 2011-08-17 2012-08-15 System and method to increase the overall diameter of veins and arteries
PCT/US2012/050983 WO2013025826A1 (en) 2011-08-17 2012-08-15 Blood pump systems and methods
US201261684534P 2012-08-17 2012-08-17
PCT/US2013/055221 WO2014028787A2 (en) 2012-08-15 2013-08-15 Blood pump systems and methods

Publications (1)

Publication Number Publication Date
HK1217921A1 true HK1217921A1 (zh) 2017-01-27

Family

ID=50101615

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16105952.7A HK1217921A1 (zh) 2012-08-15 2016-05-25 血泵系統以及方法

Country Status (14)

Country Link
EP (3) EP4252823A3 (zh)
JP (1) JP6433897B2 (zh)
KR (1) KR102352575B1 (zh)
CN (1) CN105102011B (zh)
AR (2) AR092369A1 (zh)
AU (3) AU2013302455B2 (zh)
BR (1) BR112015003061B1 (zh)
CA (2) CA3088022C (zh)
ES (1) ES2841114T3 (zh)
HK (1) HK1217921A1 (zh)
IL (2) IL237199B (zh)
RU (1) RU2677537C2 (zh)
TW (2) TW201431574A (zh)
WO (1) WO2014028787A2 (zh)

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US9555174B2 (en) 2010-02-17 2017-01-31 Flow Forward Medical, Inc. Blood pump systems and methods
KR102117201B1 (ko) 2010-02-17 2020-06-01 플로우 포워드 메디컬, 인크. 정맥의 전체 직경을 증가시키는 방법 및 시스템
US9662431B2 (en) 2010-02-17 2017-05-30 Flow Forward Medical, Inc. Blood pump systems and methods
CA2845253C (en) 2011-08-17 2022-03-01 Novita Therapeutics, Llc System and method to increase the overall diameter of veins and arteries
CA2845086C (en) 2011-08-17 2023-02-14 Novita Therapeutics, Llc Blood pump systems and methods
US10258730B2 (en) 2012-08-17 2019-04-16 Flow Forward Medical, Inc. Blood pump systems and methods
US10159786B2 (en) 2014-09-30 2018-12-25 Perqflo, Llc Hybrid ambulatory infusion pumps
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EP3812001A1 (en) * 2015-03-18 2021-04-28 Abiomed Europe GmbH Blood pump
JP6200465B2 (ja) * 2015-07-23 2017-09-20 日本ライフライン株式会社 ステントグラフト
EP3411097B8 (en) * 2016-02-02 2020-12-30 Medtronic MiniMed, Inc. Hybrid ambulatory infusion pump with contactless power transmission
JP6674802B2 (ja) * 2016-03-10 2020-04-01 国立大学法人神戸大学 遠心型血液ポンプ
EP3446728A4 (en) * 2016-04-20 2019-12-18 Sun Medical Technology Research Corporation BLOOD PUMP
BR112018072194A2 (pt) * 2016-04-29 2019-02-12 Flow Forward Medical, Inc. pontas de conduto e sistemas e métodos para uso
EP3515522A1 (en) * 2016-09-23 2019-07-31 Heartware, Inc. Physiologically responsive vad for cardiac events
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CN111491677B (zh) * 2017-12-05 2023-12-01 心脏器械股份有限公司 具有叶轮洗涤操作的血泵
WO2020068480A1 (en) * 2018-09-27 2020-04-02 Heartware, Inc. Map estimation on vad patients
CN113164736A (zh) * 2018-11-29 2021-07-23 心脏器械股份有限公司 用于心室辅助装置的血栓清除性歧管
US12097016B2 (en) 2019-03-14 2024-09-24 Abiomed, Inc. Blood flow rate measurement system
WO2021104449A1 (zh) * 2019-11-28 2021-06-03 业聚医疗器械(深圳)有限公司 一种动脉血液循环管道组件和人工动脉血液体外循环系统
FR3112579B1 (fr) * 2020-07-16 2022-09-09 Hopitaux Paris Assist Publique système de pompe à sang de déchargement
CN111882964B (zh) * 2020-08-18 2021-12-24 中国人民解放军陆军特色医学中心 一种血液透析培训用的模拟装置
CN112007233B (zh) * 2020-09-07 2022-04-08 李玉贞 一种输送液体药剂输送装置
US20230013106A1 (en) * 2021-07-16 2023-01-19 Medtronic, Inc. Header/connector thermal spreader
CN114344702B (zh) * 2021-11-29 2022-12-06 苏州心擎医疗技术有限公司 导管泵及泵体
FR3137266B1 (fr) * 2022-07-04 2024-08-02 Hopitaux Paris Assist Publique Systeme d’anastomose
CN115227964B (zh) * 2022-09-21 2022-12-27 深圳核心医疗科技有限公司 流速控制方法及装置

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JP5623203B2 (ja) * 2010-09-08 2014-11-12 テルモ株式会社 遠心式血液ポンプおよび遠心式血液ポンプ装置

Also Published As

Publication number Publication date
BR112015003061A2 (pt) 2019-12-17
KR20150080482A (ko) 2015-07-09
JP2015527138A (ja) 2015-09-17
AU2018200046A1 (en) 2018-03-15
AU2019264664B2 (en) 2021-09-02
IL237199B (en) 2019-11-28
AU2013302455A1 (en) 2015-02-19
RU2677537C2 (ru) 2019-01-17
TWI734398B (zh) 2021-07-21
RU2015108946A (ru) 2016-10-10
WO2014028787A3 (en) 2014-03-27
TW202033231A (zh) 2020-09-16
KR102352575B1 (ko) 2022-01-18
EP4252823A2 (en) 2023-10-04
AU2013302455B2 (en) 2017-10-05
CA2880279A1 (en) 2014-02-20
CA3088022C (en) 2023-02-28
CA3088022A1 (en) 2014-02-20
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EP3789062A1 (en) 2021-03-10
BR112015003061B1 (pt) 2022-02-08
EP2885019B1 (en) 2020-09-23
EP2885019A2 (en) 2015-06-24
IL269877B (en) 2021-05-31
AR092369A1 (es) 2015-04-15
WO2014028787A2 (en) 2014-02-20
JP6433897B2 (ja) 2018-12-05
AU2018200046B2 (en) 2019-08-15
ES2841114T3 (es) 2021-07-07
AU2019264664A1 (en) 2019-12-05
EP2885019A4 (en) 2016-06-08
IL237199A0 (en) 2015-04-30
TW201431574A (zh) 2014-08-16
AR116608A2 (es) 2021-05-26
CA2880279C (en) 2020-09-29
CN105102011A (zh) 2015-11-25
CN105102011B (zh) 2019-07-16

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