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HK1216534A1 - 在光動力療法和診斷中有用的二氫卟酚衍生物 - Google Patents

在光動力療法和診斷中有用的二氫卟酚衍生物

Info

Publication number
HK1216534A1
HK1216534A1 HK16104558.8A HK16104558A HK1216534A1 HK 1216534 A1 HK1216534 A1 HK 1216534A1 HK 16104558 A HK16104558 A HK 16104558A HK 1216534 A1 HK1216534 A1 HK 1216534A1
Authority
HK
Hong Kong
Prior art keywords
diagnosis
photodynamic therapy
derivative useful
chlorin derivative
chlorin
Prior art date
Application number
HK16104558.8A
Other languages
English (en)
Inventor
Honsue Cho
Original Assignee
Rmw Cho Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1222544.7A external-priority patent/GB201222544D0/en
Priority claimed from GB1309337.2A external-priority patent/GB2514408A/en
Application filed by Rmw Cho Group Ltd filed Critical Rmw Cho Group Ltd
Publication of HK1216534A1 publication Critical patent/HK1216534A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0036—Porphyrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biochemistry (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biotechnology (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • AIDS & HIV (AREA)
  • Urology & Nephrology (AREA)
  • Gastroenterology & Hepatology (AREA)
HK16104558.8A 2012-12-14 2016-04-20 在光動力療法和診斷中有用的二氫卟酚衍生物 HK1216534A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1222544.7A GB201222544D0 (en) 2012-12-14 2012-12-14 Photodynamic therapy and diagnosis
GB1309337.2A GB2514408A (en) 2013-05-23 2013-05-23 Photodynamic Therapy and Diagnosis
PCT/GB2013/053285 WO2014091241A1 (en) 2012-12-14 2013-12-13 Chlorin derivative useful in photodynamic therapy and diagnosis

Publications (1)

Publication Number Publication Date
HK1216534A1 true HK1216534A1 (zh) 2016-11-18

Family

ID=49958497

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16104558.8A HK1216534A1 (zh) 2012-12-14 2016-04-20 在光動力療法和診斷中有用的二氫卟酚衍生物

Country Status (24)

Country Link
US (1) US20150315202A1 (zh)
EP (1) EP2931728B1 (zh)
JP (1) JP6396919B2 (zh)
KR (1) KR102242404B1 (zh)
CN (2) CN105008372B (zh)
AU (2) AU2013357030B2 (zh)
CA (1) CA2894968C (zh)
CY (1) CY1122834T1 (zh)
DK (1) DK2931728T3 (zh)
ES (1) ES2791004T3 (zh)
HK (1) HK1216534A1 (zh)
HR (1) HRP20200734T1 (zh)
HU (1) HUE048861T2 (zh)
IL (1) IL239347B (zh)
LT (1) LT2931728T (zh)
ME (1) ME03725B (zh)
MY (1) MY180320A (zh)
PH (1) PH12015501341A1 (zh)
PL (1) PL2931728T3 (zh)
PT (1) PT2931728T (zh)
RS (1) RS60225B1 (zh)
SG (1) SG11201504595UA (zh)
SI (1) SI2931728T1 (zh)
WO (1) WO2014091241A1 (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3331488A4 (en) 2015-08-08 2019-04-17 CHL Industries, LLC IMPROVED HYALURONANE AND MODIFIED HYALURONAN IN BIOMEDICAL APPLICATIONS
RU2753402C1 (ru) * 2020-04-15 2021-08-16 Федеральное государтвенное бюджетное учреждение "Российский научный центр радиологии и хирургических технологий имени академика А.М. Гранова" Министерства здравоохранения Российской Федерации Способ фотодинамической терапии при лечении нерезекабельной аденокарциномы внепеченочных желчных протоков
GB202018667D0 (en) * 2020-11-26 2021-01-13 Rmw Cho Group Ltd Photodynamic therapy and diagnosis
CN113527319B (zh) * 2021-06-10 2023-03-07 中国人民解放军海军军医大学 一种新型二氢卟吩e4衍生物及其药学上可接受的盐和制备方法与应用
GB202217864D0 (en) 2022-11-28 2023-01-11 Rmw Cho Group Ltd Novel compounds
WO2024115525A2 (en) 2022-11-28 2024-06-06 Rmw Cho Group Limited Novel compounds
WO2024115524A1 (en) 2022-11-28 2024-06-06 Rmw Cho Group Limited Porphyrin and phosphonium-porphyrin based compounds for photodynamic therapy and diagnostics
GB202217863D0 (en) 2022-11-28 2023-01-11 Rmw Cho Group Ltd Novel compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5002962A (en) * 1988-07-20 1991-03-26 Health Research, Inc. Photosensitizing agents
JP2963178B2 (ja) * 1990-09-27 1999-10-12 株式会社エス・エル・ティ・ジャパン 水溶性フェオホーバイドａの製造方法
CN1148184C (zh) * 1999-10-28 2004-05-05 上海复旦张江生物医药股份有限公司 光动力治疗肿瘤药物组合物
RU2183956C1 (ru) * 2001-03-30 2002-06-27 Общество с ограниченной ответственностью "РАДА-ФАРМА" Фотосенсибилизатор и способ его получения
US20050020559A1 (en) * 2001-10-03 2005-01-27 Robinson Byron C Chlorin photosensitizing agents for use in photodynamic therapy
CN100443485C (zh) * 2005-04-08 2008-12-17 吴华君 叶绿酸合铁钠盐衍生物、制备方法及用途
GB0718878D0 (en) * 2007-09-28 2007-11-07 Photo Diagnostic Devices Pdd L Photodynamic Theraphy and diagnosis

Also Published As

Publication number Publication date
JP6396919B2 (ja) 2018-09-26
AU2018282411A1 (en) 2019-01-17
LT2931728T (lt) 2020-06-10
EP2931728B1 (en) 2020-02-19
DK2931728T3 (da) 2020-05-11
RS60225B1 (sr) 2020-06-30
EP2931728A1 (en) 2015-10-21
AU2013357030B2 (en) 2018-03-29
WO2014091241A1 (en) 2014-06-19
CA2894968C (en) 2023-02-14
IL239347A0 (en) 2015-07-30
CN105008372A (zh) 2015-10-28
PL2931728T3 (pl) 2020-11-02
KR20150096432A (ko) 2015-08-24
HUE048861T2 (hu) 2020-08-28
AU2013357030A1 (en) 2014-06-19
CY1122834T1 (el) 2021-05-05
IL239347B (en) 2018-07-31
HRP20200734T1 (hr) 2020-09-18
ME03725B (me) 2021-01-20
SI2931728T1 (sl) 2020-08-31
US20150315202A1 (en) 2015-11-05
PH12015501341B1 (en) 2015-09-07
MY180320A (en) 2020-11-28
ES2791004T3 (es) 2020-10-30
JP2016502999A (ja) 2016-02-01
SG11201504595UA (en) 2015-07-30
CN110003225A (zh) 2019-07-12
KR102242404B1 (ko) 2021-04-21
AU2013357030A8 (en) 2015-07-16
CN105008372B (zh) 2020-01-17
PH12015501341A1 (en) 2015-09-07
PT2931728T (pt) 2020-04-29
CA2894968A1 (en) 2014-06-19

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