HK1204227A1 - Benzamide derivatives - Google Patents
Benzamide derivativesInfo
- Publication number
- HK1204227A1 HK1204227A1 HK15104888.0A HK15104888A HK1204227A1 HK 1204227 A1 HK1204227 A1 HK 1204227A1 HK 15104888 A HK15104888 A HK 15104888A HK 1204227 A1 HK1204227 A1 HK 1204227A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- benzamide derivatives
- benzamide
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21968109P | 2009-06-23 | 2009-06-23 | |
| PCT/US2010/038290 WO2010151441A1 (en) | 2009-06-23 | 2010-06-11 | Benzamide derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1204227A1 true HK1204227A1 (en) | 2015-11-13 |
Family
ID=43386841
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK15104888.0A HK1204227A1 (en) | 2009-06-23 | 2015-05-22 | Benzamide derivatives |
Country Status (9)
| Country | Link |
|---|---|
| US (4) | US9125901B2 (en) |
| EP (1) | EP2445345B1 (en) |
| JP (1) | JP5868851B2 (en) |
| CN (1) | CN104219954B (en) |
| AU (1) | AU2010263113B2 (en) |
| CA (1) | CA2766550C (en) |
| HK (1) | HK1204227A1 (en) |
| IL (1) | IL217183A (en) |
| WO (1) | WO2010151441A1 (en) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2766550C (en) * | 2009-06-23 | 2017-04-11 | The Translational Genomics Research Intstitute | Benzamide derivatives |
| PE20170143A1 (en) * | 2014-02-11 | 2017-03-19 | Bayer Pharma AG | BENZIMIDAZOLE-2-AMINES AS MIDH1 INHIBITORS |
| EP3105210B1 (en) * | 2014-02-11 | 2019-01-30 | Bayer Pharma Aktiengesellschaft | Benzimidazol-2-amines as midh1 inhibitors |
| ES2814151T3 (en) * | 2014-10-23 | 2021-03-26 | Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts | 1-Cyclohexyl-2-phenylaminobenzimidazoles as MIDH1 inhibitors for the treatment of tumors |
| US10138226B2 (en) | 2014-10-23 | 2018-11-27 | Bayer Pharma Aktiengesellschaft | Benzimidazol-2-amines as MIDH1 inhibitors |
| MA42032A (en) | 2015-02-02 | 2018-03-14 | Forma Therapeutics Inc | 3-ARYL-4-AMIDO-BICYCLO [4,5,0] HYDROXAMIC ACIDS AS HDAC INHIBITORS |
| AR103598A1 (en) | 2015-02-02 | 2017-05-24 | Forma Therapeutics Inc | BICYCLIC ACIDS [4,6,0] HYDROXAMICS AS HDAC INHIBITORS |
| CA3025145A1 (en) | 2015-05-22 | 2016-12-01 | Translational Drug Development Llc | Benzamide and active compound compositions and methods of use |
| EP3303302B1 (en) | 2015-06-08 | 2019-03-20 | Bayer Pharma Aktiengesellschaft | N-menthylbenzimidazoles as midh1 inhibitors |
| WO2017009325A1 (en) | 2015-07-16 | 2017-01-19 | Bayer Pharma Aktiengesellschaft | 5-hydroxyalkylbenzimidazoles as midh1 inhibitors |
| TW201718513A (en) * | 2015-07-27 | 2017-06-01 | 拜耳製藥公司 | Method for preparing substituted 3-(2-anilino-1-cyclohexyl-1H-benzimidazol-5-yl)propanoic acid derivatives |
| TW201708193A (en) * | 2015-07-27 | 2017-03-01 | 拜耳製藥公司 | Inhibiton of the mutated isocitrate dehydrogenase IDH1 R132H |
| US20190040017A1 (en) * | 2016-03-02 | 2019-02-07 | Translational Drug Development Llc | Aminobenzimidazole derivatives |
| US10555935B2 (en) | 2016-06-17 | 2020-02-11 | Forma Therapeutics, Inc. | 2-spiro-5- and 6-hydroxamic acid indanes as HDAC inhibitors |
| IL300095A (en) * | 2016-11-23 | 2023-03-01 | Translational Drug Dev Llc | Compositions of benzamide and an agonist for the cancer necrosis factor receptor superfamily and uses thereof |
| IL305302A (en) * | 2017-09-06 | 2023-10-01 | Translational Drug Dev Llc | Aminobenzimidazole derivatives, treatments, and methods of inhibiting histone deacetylase |
| KR102117083B1 (en) | 2018-10-30 | 2020-05-29 | 계명대학교 산학협력단 | Benzoheterocycle compounds and composition for preventing or treating cancer diseases comprising the same |
| CN112209884B (en) * | 2019-07-12 | 2022-11-11 | 杭州梯诺医药科技有限公司 | 1-H benzimidazole derivative, preparation method and application thereof |
| CN119421875A (en) * | 2022-06-24 | 2025-02-11 | 巴斯夫欧洲公司 | New carboxyl ligands and their applications in catalysts |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US299039A (en) * | 1884-05-20 | Electric multiple-switch-board system | ||
| FR2833948B1 (en) * | 2001-12-21 | 2004-02-06 | Sod Conseils Rech Applic | NOVEL BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS MEDICAMENTS |
| ATE447404T1 (en) | 2002-03-29 | 2009-11-15 | Novartis Vaccines & Diagnostic | SUBSTITUTED BENZAZOLES AND THEIR USE AS RAF-KINASE INHIBITORS |
| PE20040844A1 (en) | 2002-11-26 | 2004-12-30 | Novartis Ag | PHENYLACETIC ACIDS AND DERIVATIVES AS COX-2 INHIBITORS |
| FR2851563B1 (en) * | 2003-02-26 | 2005-04-22 | Sod Conseils Rech Applic | NOVEL BENZIMIDAZOLE AND IMIDAZO-PYRIDINE DERIVATIVES AND THEIR USE AS A MEDICINAL PRODUCT |
| KR20100012046A (en) * | 2003-04-07 | 2010-02-04 | 파마시클릭스, 인코포레이티드 | Novel hydroxamates as therapeutic agents |
| CN1997626A (en) * | 2004-07-12 | 2007-07-11 | 默克公司 | Inhibitors of histone deacetylase |
| US7642275B2 (en) * | 2004-12-16 | 2010-01-05 | Takeda San Diego, Inc. | Histone deacetylase inhibitors |
| US7772245B2 (en) | 2005-02-14 | 2010-08-10 | Miikana Therapeutics, Inc. | Inhibitors of histone deacetylase |
| CN101379060B (en) * | 2006-02-10 | 2012-05-23 | 转化技术制药公司 | Benzazole derivatives, compositions, and methods of use as Aurora kinase inhibitors |
| WO2008031016A2 (en) | 2006-09-08 | 2008-03-13 | The Regents Of The University Of California | Heterocyclic ligands for integrin imaging and therapy |
| WO2008153701A1 (en) * | 2007-05-24 | 2008-12-18 | Schering Corporation | Compounds for inhibiting ksp kinesin activity |
| WO2009002534A1 (en) | 2007-06-26 | 2008-12-31 | Gilead Colorado, Inc. | Imidazopyridinyl thiazolyl histone deacetylase inhibitors |
| CA2766550C (en) * | 2009-06-23 | 2017-04-11 | The Translational Genomics Research Intstitute | Benzamide derivatives |
-
2010
- 2010-06-11 CA CA2766550A patent/CA2766550C/en active Active
- 2010-06-11 JP JP2012517571A patent/JP5868851B2/en active Active
- 2010-06-11 WO PCT/US2010/038290 patent/WO2010151441A1/en active Application Filing
- 2010-06-11 CN CN201080033226.1A patent/CN104219954B/en active Active
- 2010-06-11 US US13/380,213 patent/US9125901B2/en active Active
- 2010-06-11 EP EP20100792517 patent/EP2445345B1/en active Active
- 2010-06-11 AU AU2010263113A patent/AU2010263113B2/en active Active
-
2011
- 2011-12-25 IL IL21718311A patent/IL217183A/en active IP Right Grant
-
2015
- 2015-05-22 HK HK15104888.0A patent/HK1204227A1/en unknown
- 2015-06-08 US US14/733,952 patent/US9464059B2/en active Active
-
2016
- 2016-08-23 US US15/245,166 patent/US20160362382A1/en not_active Abandoned
-
2018
- 2018-10-16 US US16/161,926 patent/US10590088B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2010151441A1 (en) | 2010-12-29 |
| AU2010263113B2 (en) | 2015-11-26 |
| US9464059B2 (en) | 2016-10-11 |
| EP2445345B1 (en) | 2014-08-27 |
| CA2766550C (en) | 2017-04-11 |
| CA2766550A1 (en) | 2010-12-29 |
| JP5868851B2 (en) | 2016-02-24 |
| US20120142922A1 (en) | 2012-06-07 |
| US10590088B2 (en) | 2020-03-17 |
| JP2012531416A (en) | 2012-12-10 |
| IL217183A (en) | 2015-02-26 |
| US20190084940A1 (en) | 2019-03-21 |
| EP2445345A4 (en) | 2013-04-24 |
| EP2445345A1 (en) | 2012-05-02 |
| AU2010263113A1 (en) | 2012-02-16 |
| US20150284336A1 (en) | 2015-10-08 |
| CN104219954B (en) | 2017-03-22 |
| US20160362382A1 (en) | 2016-12-15 |
| CN104219954A (en) | 2014-12-17 |
| US9125901B2 (en) | 2015-09-08 |
| IL217183A0 (en) | 2012-02-29 |
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