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HK1201463A1 - -特異性 -衍生的支架及其使用方法 - Google Patents

-特異性 -衍生的支架及其使用方法

Info

Publication number
HK1201463A1
HK1201463A1 HK15102049.0A HK15102049A HK1201463A1 HK 1201463 A1 HK1201463 A1 HK 1201463A1 HK 15102049 A HK15102049 A HK 15102049A HK 1201463 A1 HK1201463 A1 HK 1201463A1
Authority
HK
Hong Kong
Prior art keywords
cd40l
methods
specific
derived scaffolds
scaffolds
Prior art date
Application number
HK15102049.0A
Other languages
English (en)
Inventor
Anthony Coyle
Manuel Baca
Thomas Thisted
Stacey Drabic
Luba Grinberg
Shabazz Novarra
Vaheh Oganesyan
Ronald Herbst
David Kenneth Spencer
Original Assignee
Medimmune Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medimmune Llc filed Critical Medimmune Llc
Publication of HK1201463A1 publication Critical patent/HK1201463A1/zh

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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
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    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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    • C07K2318/20—Antigen-binding scaffold molecules wherein the scaffold is not an immunoglobulin variable region or antibody mimetics
    • C—CHEMISTRY; METALLURGY
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    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
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    • C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
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  • Veterinary Medicine (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
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  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Theoretical Computer Science (AREA)
  • Computing Systems (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
HK15102049.0A 2011-10-11 2015-03-02 -特異性 -衍生的支架及其使用方法 HK1201463A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161546028P 2011-10-11 2011-10-11
PCT/US2012/059477 WO2013055745A2 (en) 2011-10-11 2012-10-10 Cd40l-specific tn3-derived scaffolds and methods of use thereof

Publications (1)

Publication Number Publication Date
HK1201463A1 true HK1201463A1 (zh) 2015-09-04

Family

ID=48082729

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15102049.0A HK1201463A1 (zh) 2011-10-11 2015-03-02 -特異性 -衍生的支架及其使用方法

Country Status (22)

Country Link
US (4) US10000553B2 (zh)
EP (2) EP2771022B1 (zh)
JP (4) JP6140712B2 (zh)
KR (4) KR102434073B1 (zh)
CN (3) CN116063509A (zh)
AU (1) AU2012323316B2 (zh)
BR (1) BR112014008804A2 (zh)
CA (1) CA2851667A1 (zh)
CY (1) CY1123690T1 (zh)
DK (1) DK2771022T3 (zh)
ES (1) ES2819075T3 (zh)
HK (1) HK1201463A1 (zh)
HR (1) HRP20201513T1 (zh)
HU (1) HUE051439T2 (zh)
LT (1) LT2771022T (zh)
MX (2) MX367013B (zh)
PT (1) PT2771022T (zh)
RS (1) RS60828B1 (zh)
RU (1) RU2704992C2 (zh)
SG (2) SG11201400567QA (zh)
SI (1) SI2771022T1 (zh)
WO (1) WO2013055745A2 (zh)

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ES2819075T3 (es) * 2011-10-11 2021-04-14 Viela Bio Inc Matrices de soporte derivadas de TN3 específicas para CD40L y sus métodos de empleo
MA41044A (fr) 2014-10-08 2017-08-15 Novartis Ag Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer
PT3218406T (pt) 2014-11-10 2021-06-17 Medimmune Ltd Moléculas de ligação específicas para cd73 e seus usos
US10683340B2 (en) 2015-03-12 2020-06-16 Medimmune, Llc Method of purifying albumin-fusion proteins
KR101810778B1 (ko) * 2015-06-23 2017-12-20 서울대학교산학협력단 Cd154 결합 폴리펩타이드 및 그 용도
PE20180802A1 (es) 2015-08-05 2018-05-09 Janssen Biotech Inc Anticuerpos anti-cd154 y metodos de uso de estos
US11958913B2 (en) * 2017-01-09 2024-04-16 Biomunex Pharmaceuticals Polypeptide linker for preparing multispecific antibodies
US11905313B2 (en) * 2017-11-28 2024-02-20 The United States of America, as represented by the Secretary, Department of Health and Human Services. Recombinant RSV G proteins and their use
US20210317220A1 (en) * 2018-09-24 2021-10-14 Janssen Biotech, Inc. Method of providing safe administration of an anti-cd154 antibody
CA3114394A1 (en) * 2018-09-26 2020-04-02 Viela Bio, Inc. Cd40l antagonist and uses thereof
WO2020086885A2 (en) * 2018-10-24 2020-04-30 Brandeis University Multivalent glycopeptides that tightly bind to carbohydrate-binding monoclonal antibody family pgt128
CN113227135A (zh) 2018-12-28 2021-08-06 斯帕克斯治疗公司 用于治疗癌症和其他疾病的对紧密连接蛋白18.2具有特异性的结合分子、其组合物和方法
CN111440253B (zh) * 2019-01-17 2021-08-27 中国科学院上海药物研究所 立方形环糊精骨架-rgd组合物及其制备方法
EP4340867A1 (en) * 2021-05-21 2024-03-27 Viela Bio, Inc. Cd40l antagonist and uses thereof in the treatment of lupus nephritis
WO2024211211A1 (en) 2023-04-03 2024-10-10 Regeneron Pharmaceuticals, Inc. Methods of improving transplant survival using il-2 receptor gamma chain antibodies

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