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HK1247255A1 - 底數大於2的指數核酸擴增 - Google Patents

底數大於2的指數核酸擴增

Info

Publication number
HK1247255A1
HK1247255A1 HK18106922.0A HK18106922A HK1247255A1 HK 1247255 A1 HK1247255 A1 HK 1247255A1 HK 18106922 A HK18106922 A HK 18106922A HK 1247255 A1 HK1247255 A1 HK 1247255A1
Authority
HK
Hong Kong
Prior art keywords
nucleic acid
acid amplification
exponential base
exponential
base
Prior art date
Application number
HK18106922.0A
Other languages
English (en)
Inventor
R‧希古奇
Original Assignee
Cepheid
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cepheid filed Critical Cepheid
Publication of HK1247255A1 publication Critical patent/HK1247255A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/155—Modifications characterised by incorporating/generating a new priming site
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/161—Modifications characterised by incorporating target specific and non-target specific sites
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/191—Modifications characterised by incorporating an adaptor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2531/00—Reactions of nucleic acids characterised by
    • C12Q2531/10—Reactions of nucleic acids characterised by the purpose being amplify/increase the copy number of target nucleic acid
    • C12Q2531/119—Strand displacement amplification [SDA]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HK18106922.0A 2014-12-15 2018-05-28 底數大於2的指數核酸擴增 HK1247255A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462092102P 2014-12-15 2014-12-15
PCT/US2015/065890 WO2016100388A1 (en) 2014-12-15 2015-12-15 Exponential base-greater-than-2 nucleic acid amplification

Publications (1)

Publication Number Publication Date
HK1247255A1 true HK1247255A1 (zh) 2018-09-21

Family

ID=55071208

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18106922.0A HK1247255A1 (zh) 2014-12-15 2018-05-28 底數大於2的指數核酸擴增

Country Status (11)

Country Link
US (3) US10273534B2 (zh)
EP (1) EP3234188B1 (zh)
JP (1) JP6804462B2 (zh)
CN (2) CN107429292B (zh)
AU (2) AU2015362617B2 (zh)
CA (1) CA2971006C (zh)
DK (1) DK3234188T3 (zh)
ES (1) ES2764975T3 (zh)
HK (1) HK1247255A1 (zh)
PT (1) PT3234188T (zh)
WO (1) WO2016100388A1 (zh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107429292B (zh) 2014-12-15 2021-12-17 塞弗德公司 底数大于2的指数核酸扩增
EP3287528A1 (de) 2016-08-25 2018-02-28 AGCT GmbH Verfahren zur amplifikation von nukleinsäuren und kit zu dessen durchführung
WO2019162529A1 (de) * 2018-02-26 2019-08-29 Agct Gmbh Verfahren zur primer-verlängerungsreaktion mit verbesserter spezifität
CN112074612A (zh) * 2018-02-26 2020-12-11 Agct有限公司 一种具有更高特异性的核酸扩增方法
US20210071244A1 (en) * 2018-02-28 2021-03-11 Agct Gmbh Method for the amplification of a nucleic acid with improved specificity
CN113227398A (zh) * 2018-10-29 2021-08-06 塞弗德公司 在减少的扩增时间下使用巢式重叠引物的指数基数-3核酸扩增
WO2021222144A1 (en) * 2020-04-27 2021-11-04 Cepheid Exponential base-3 and greater nucleic acid amplification with cycling probe
JP2024501832A (ja) 2020-12-24 2024-01-16 インテグレイテツド・デイー・エヌ・エイ・テクノロジーズ・インコーポレイテツド 高忠実度ＤＮＡポリメラーゼによるｒｈＰＣＲベース増幅産物シーケンシングにおいて、プライマー二量体及びオフターゲット増幅を低減するＲＮアーゼＨ２突然変異体
WO2023158644A1 (en) * 2022-02-15 2023-08-24 Cepheid Exponential base-greater-than-base 2 nucleic acid amplification using high- and low-tm primers
US20240336961A1 (en) * 2023-02-23 2024-10-10 Cepheid USE OF DESTABILIZING NUCLEOTIDE TRIPHOSPHATES TO REDUCE AMPLICON FOLDING AND Tm

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US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US5449602A (en) 1988-01-13 1995-09-12 Amoco Corporation Template-directed photoligation
US5494810A (en) 1990-05-03 1996-02-27 Cornell Research Foundation, Inc. Thermostable ligase-mediated DNA amplifications system for the detection of genetic disease
AU8132994A (en) * 1993-11-05 1995-05-23 Board Of Trustees Of The Leland Stanford Junior University Nucleic acids encoding {his5, trp7, tyr8}-gnrh preprohormone and {ser8}-gnrh preprohormone and their uses
EP1958955B1 (en) 1996-02-09 2013-09-04 Cornell Research Foundation, Inc. Spatially addressable oligonucleotide arrays and method of making the same
EP0912761A4 (en) 1996-05-29 2004-06-09 Cornell Res Foundation Inc DETERMINATION OF DIFFERENCES IN THE NUCLEIC ACID SEQUENCE BY MEANS OF A COMBINATION OF LIGASE DETERMINATION AND POLYMERASE CHAIN REACTION
US6312892B1 (en) 1996-07-19 2001-11-06 Cornell Research Foundation, Inc. High fidelity detection of nucleic acid differences by ligase detection reaction
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US6770748B2 (en) 1997-03-07 2004-08-03 Takeshi Imanishi Bicyclonucleoside and oligonucleotide analogue
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US6794499B2 (en) 1997-09-12 2004-09-21 Exiqon A/S Oligonucleotide analogues
US6027998A (en) 1997-12-17 2000-02-22 Advanced Micro Devices, Inc. Method for fully planarized conductive line for a stack gate
US6506594B1 (en) 1999-03-19 2003-01-14 Cornell Res Foundation Inc Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays
US6818185B1 (en) 1999-05-28 2004-11-16 Cepheid Cartridge for conducting a chemical reaction
ATE302263T1 (de) 1999-05-28 2005-09-15 Cepheid Anlage zum brechen von zellen
US6262490B1 (en) 1999-11-05 2001-07-17 Advanced Semiconductor Engineering, Inc. Substrate strip for use in packaging semiconductor chips
RU2252964C2 (ru) * 1999-11-08 2005-05-27 Эйкен Кагаку Кабусики Кайся Способ и набор для синтеза нуклеиновой кислоты, имеющей нуклеотидную последовательность, где в одной цепи попеременно связаны комплементарные нуклеотидные последовательности
US6403037B1 (en) 2000-02-04 2002-06-11 Cepheid Reaction vessel and temperature control system
AU2001265121A1 (en) 2000-05-30 2001-12-11 Applera Corporation Methods for detecting target nucleic acids using coupled ligation and amplification
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CA2734868C (en) * 2008-08-26 2019-09-10 Fluidigm Corporation Assay methods for increased throughput of samples and/or targets
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CN102559928A (zh) * 2011-12-28 2012-07-11 中国海洋大学 特异性引物组、包含其的试剂盒、使用方法及检测方法
KR20130107881A (ko) * 2012-03-23 2013-10-02 삼성테크윈 주식회사 클라미디아 및 임균 유래의 표적 유전자를 동시에 증폭하고 검출하기 위한 멀티 플렉스 키트 및 이를 이용한 진단 방법
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WO2014164479A1 (en) 2013-03-11 2014-10-09 Elitech Holding B.V. Methods for true isothermal strand displacement amplification
CN107429292B (zh) 2014-12-15 2021-12-17 塞弗德公司 底数大于2的指数核酸扩增
WO2019162529A1 (de) 2018-02-26 2019-08-29 Agct Gmbh Verfahren zur primer-verlängerungsreaktion mit verbesserter spezifität
CN113227398A (zh) 2018-10-29 2021-08-06 塞弗德公司 在减少的扩增时间下使用巢式重叠引物的指数基数-3核酸扩增

Also Published As

Publication number Publication date
US11952621B2 (en) 2024-04-09
JP2017537658A (ja) 2017-12-21
US20180066304A1 (en) 2018-03-08
CN107429292B (zh) 2021-12-17
ES2764975T3 (es) 2020-06-05
WO2016100388A1 (en) 2016-06-23
PT3234188T (pt) 2020-01-16
AU2022203553B2 (en) 2024-08-08
AU2022203553A1 (en) 2022-06-16
US10273534B2 (en) 2019-04-30
JP6804462B2 (ja) 2020-12-23
CN114369596A (zh) 2022-04-19
CA2971006C (en) 2024-05-21
CN107429292A (zh) 2017-12-01
EP3234188A1 (en) 2017-10-25
AU2015362617B2 (en) 2022-03-03
DK3234188T3 (da) 2020-01-20
AU2015362617A1 (en) 2017-06-29
EP3234188B1 (en) 2019-10-23
US11028434B2 (en) 2021-06-08
CA2971006A1 (en) 2016-06-23
US20210395797A1 (en) 2021-12-23
US20190203266A1 (en) 2019-07-04

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