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HK1246155A1 - 磷酸泛酰巰基乙胺化合物單獨或與hmg-coa還原酶抑制劑聯合用於降低血清胆固醇和血清三酸甘油酯 - Google Patents

磷酸泛酰巰基乙胺化合物單獨或與hmg-coa還原酶抑制劑聯合用於降低血清胆固醇和血清三酸甘油酯

Info

Publication number
HK1246155A1
HK1246155A1 HK18105574.3A HK18105574A HK1246155A1 HK 1246155 A1 HK1246155 A1 HK 1246155A1 HK 18105574 A HK18105574 A HK 18105574A HK 1246155 A1 HK1246155 A1 HK 1246155A1
Authority
HK
Hong Kong
Prior art keywords
serum
triglicerides
phosphopantetheine
hmg
combination
Prior art date
Application number
HK18105574.3A
Other languages
English (en)
Inventor
Gregor Kosec
Stefan Fujs
Hrvoje Petkovic
Oda Cornelia Maria Sibon
Balaji Srinivasan
Original Assignee
Acies Bio D O O
Univ Groningen
Academisch Ziekenhuis Groningen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acies Bio D O O, Univ Groningen, Academisch Ziekenhuis Groningen filed Critical Acies Bio D O O
Publication of HK1246155A1 publication Critical patent/HK1246155A1/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/661Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/345Nitrofurans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK18105574.3A 2014-12-23 2018-04-30 磷酸泛酰巰基乙胺化合物單獨或與hmg-coa還原酶抑制劑聯合用於降低血清胆固醇和血清三酸甘油酯 HK1246155A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SI201400452A SI24899A (sl) 2014-12-23 2014-12-23 Fosfopanteteinske spojine,same ali v kombinaciji z inhibitorji HMG-COA reduktaze za zniževanje serumskega holesterola in serumskih trigliceridov
PCT/EP2015/081184 WO2016102680A1 (en) 2014-12-23 2015-12-23 Phosphopantetheine compounds alone or in combination with hmg-coa reductase inhibitors for lowering serum cholesterol and serum triglicerides

Publications (1)

Publication Number Publication Date
HK1246155A1 true HK1246155A1 (zh) 2018-09-07

Family

ID=55022496

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18105574.3A HK1246155A1 (zh) 2014-12-23 2018-04-30 磷酸泛酰巰基乙胺化合物單獨或與hmg-coa還原酶抑制劑聯合用於降低血清胆固醇和血清三酸甘油酯

Country Status (7)

Country Link
US (1) US10624908B2 (zh)
EP (1) EP3236958A1 (zh)
AU (1) AU2015370919A1 (zh)
CA (1) CA2970852A1 (zh)
HK (1) HK1246155A1 (zh)
SI (1) SI24899A (zh)
WO (1) WO2016102680A1 (zh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3887353A1 (en) * 2018-11-30 2021-10-06 Comet Therapeutics, Inc. Pantetheine derivatives and uses thereof
EP3947347A1 (en) * 2019-03-27 2022-02-09 Comet Therapeutics, Inc. Pantethenoylcysteine derivatives and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA05000050A (es) 2002-07-03 2005-04-08 Esperion Therapeutics Inc Composiciones farmaceuticas y metodos para tratar, prevenir y manejar el colesterol, dislipidemia y enfermedades relacionadas.
CN102596165A (zh) 2009-09-11 2012-07-18 第一精密化学股份有限公司 含有泛硫乙胺磷酸酯的外用剂
EP2869717B8 (en) * 2012-07-09 2018-07-25 NoGlo, Inc. Prevention of alcohol reaction with dietary supplements
EP2868662A1 (en) 2013-11-04 2015-05-06 Acies Bio d.o.o. Stable pantetheine derivatives for the treatment of pantothenate kinase associated neurodegeneration (pkan) and methods for the synthesis of such compounds

Also Published As

Publication number Publication date
US10624908B2 (en) 2020-04-21
SI24899A (sl) 2016-06-30
US20180214461A1 (en) 2018-08-02
WO2016102680A1 (en) 2016-06-30
CA2970852A1 (en) 2016-06-30
EP3236958A1 (en) 2017-11-01
AU2015370919A1 (en) 2017-07-06

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