HK1199882A1 - 用於製備雌四醇的方法 - Google Patents

用於製備雌四醇的方法

Info

Publication number: HK1199882A1
Authority: HK; Hong Kong
Prior art keywords: estetrol; production
Prior art date: 2011-10-07

Application number

HK15100344.6A

Other languages

English (en)

Inventor

Jean-Claude Pascal

Original Assignee

Estetra Sprl

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2011-10-07

Filing date

2015-01-13

Publication date

2015-07-24

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48043195&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1199882(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2015-01-13 Application filed by Estetra Sprl filed Critical Estetra Sprl

2015-07-24 Publication of HK1199882A1 publication Critical patent/HK1199882A1/zh

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Steroid Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

HK15100344.6A 2011-10-07 2015-01-13 用於製備雌四醇的方法 HK1199882A1 (zh)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US201161544591P	2011-10-07	2011-10-07
EP11184278		2011-10-07
PCT/EP2012/069761 WO2013050553A1 (en)	2011-10-07	2012-10-05	Process for the production of estetrol

Publications (1)

Publication Number	Publication Date
HK1199882A1 true HK1199882A1 (zh)	2015-07-24

Family

ID=48043195

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HK15100344.6A HK1199882A1 (zh)	2011-10-07	2015-01-13	用於製備雌四醇的方法

Country Status (27)

Country	Link
US (1)	US8987484B2 (zh)
EP (1)	EP2764008B1 (zh)
JP (1)	JP6196625B2 (zh)
KR (1)	KR102007874B1 (zh)
CN (1)	CN103890001B (zh)
AU (1)	AU2012320423C1 (zh)
BR (1)	BR112014008196B8 (zh)
CA (1)	CA2847813C (zh)
CL (1)	CL2014000802A1 (zh)
CY (1)	CY1118674T1 (zh)
DK (1)	DK2764008T3 (zh)
EA (1)	EA024003B1 (zh)
ES (1)	ES2593316T3 (zh)
HK (1)	HK1199882A1 (zh)
HR (1)	HRP20161282T1 (zh)
HU (1)	HUE028963T2 (zh)
IN (1)	IN2014MN00841A (zh)
LT (1)	LT2764008T (zh)
ME (1)	ME02527B (zh)
MX (1)	MX348917B (zh)
PL (1)	PL2764008T3 (zh)
PT (1)	PT2764008T (zh)
RS (1)	RS55231B1 (zh)
SG (1)	SG11201401282PA (zh)
SI (1)	SI2764008T1 (zh)
SM (1)	SMT201600375B (zh)
WO (1)	WO2013050553A1 (zh)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EA023991B1 (ru)	2011-06-01	2016-08-31	Эстетра С.П.Р.Л.	Способ получения интермедиатов эстетрола
CN103619867B (zh)	2011-06-01	2015-12-23	埃斯特拉公司	用于产生雌四醇中间体的方法
EP2383279A1 (en)	2011-07-19	2011-11-02	Pantarhei Bioscience B.V.	Process for the preparation of estetrol
WO2013034780A2 (en) *	2012-12-20	2013-03-14	Crystal Pharma, S.A.U.	Process for the preparation of estetrol and related compounds
WO2015040051A1 (en)	2013-09-18	2015-03-26	Crystal Pharma, S.A.U.	Process for the preparation of estetrol
HRP20211968T1 (hr)	2015-06-18	2022-03-18	Estetra Srl	Orodisperzibilna jedinica za doziranje koja sadrži komponentu estetrola
NO3106148T3 (zh)	2015-06-18	2018-08-11
RS61777B1 (sr) *	2015-06-18	2021-06-30	Estetra Sprl	Oralno-disperzibilna tableta koja sadrži estetrol
ES2877186T3 (es)	2015-06-18	2021-11-16	Estetra Sprl	Comprimido orodispersable que contiene estetrol
KR102712911B1 (ko)	2016-08-05	2024-10-04	에스테트라, 소시에떼 아 레스폰서빌리떼 리미떼	월경통 및 생리통의 관리방법
JOP20200260A1 (ar)	2018-04-19	2019-10-19	Estetra Sprl	مركبات واستخداماتها للتخفيف من الأعراض المصاحبة لانقطاع الطمث
TWI801561B (zh)	2018-04-19	2023-05-11	比利時商依思特拉私人有限責任公司	化合物及其用於緩解絕經相關症狀的用途
EP3647413A1 (en) *	2018-10-31	2020-05-06	Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas O.A., M.P. (CIEMAT)	Improvements for performing and facilitating the recovery after hematopoietic stem cell transplantation
HU231240B1 (hu) *	2019-09-03	2022-04-28	Richter Gedeon Nyrt.	Ipari eljárás nagytisztaságú ösztetrol hatóanyag előállítására
IT201900021879A1 (it)	2019-11-22	2021-05-22	Ind Chimica Srl	PROCESSO PER LA PREPARAZIONE DI (15α,16α,17β)-ESTRA-1,3,5(10)-TRIENE-3,15,16,17-TETROLO (ESTETROLO) ED INTERMEDI DI DETTO PROCESSO
IT201900017414A1 (it)	2019-09-27	2021-03-27	Ind Chimica Srl	Processo per la preparazione di (15α,16α,17β)-estra-1,3,5(10)-triene-3,15,16,17-tetrolo (Estetrolo) ed intermedi di detto processo
AU2020355615B2 (en)	2019-09-27	2023-12-14	Industriale Chimica S.R.L.	Process for preparing (15α,16α,17β)-Estra-1,3,5(10)-Triene-3,15,16,17-Tetrol (Estetrol) and intermediates of said process
IT202100019631A1 (it)	2021-07-23	2023-01-23	Newchem S P A	Metodo per produrre estetrolo e i suoi intermedi
WO2023021026A1 (en) *	2021-08-17	2023-02-23	Aspen Oss B.V.	A synthetic pathway to estra-1,3,5(10)-triene-3,15a,16a,17b-tetrol
WO2023051937A1 (en)	2021-10-01	2023-04-06	Industriale Chimica S.R.L.	Process for preparing (15alpha,16alpha,17 eta)-estra-1,3,5(10)-triene-3,15,16,17-tetrol (estetrol) monohydrate
WO2024160373A1 (en)	2023-02-02	2024-08-08	Industriale Chimica S.R.L.	PROCESS FOR PREPARING (15α,16α,17β)-ESTRA-1,3,5(10)-TRIENE-3,15,16,17-TETROL (ESTETROL) MONOHYDRATE

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW548277B (en) *	1999-07-16	2003-08-21	Akzo Nobel Nv	Orally active androgens
IL149424A (en) *	1999-12-02	2007-05-15	Organon Nv	Androgens are converted to methylene at positions 15,14
US20060211669A1 (en) *	2002-11-08	2006-09-21	Verhaar Mark T	Synthesis of estetrol via estrone derived steroids
UA89964C2 (ru) *	2004-09-08	2010-03-25	Н.В. Органон	15β-ЗАМЕЩЕННЫЕ СТЕРОИДЫ, КОТОРЫЕ ИМЕЮТ СЕЛЕКТИВНУЮ ЭСТРОГЕННУЮ АКТИВНОСТЬ
CN103619867B (zh)	2011-06-01	2015-12-23	埃斯特拉公司	用于产生雌四醇中间体的方法
EA023991B1 (ru)	2011-06-01	2016-08-31	Эстетра С.П.Р.Л.	Способ получения интермедиатов эстетрола
EP2383279A1 (en) *	2011-07-19	2011-11-02	Pantarhei Bioscience B.V.	Process for the preparation of estetrol

2012
- 2012-10-05 EP EP12778664.8A patent/EP2764008B1/en active Active
- 2012-10-05 PL PL12778664T patent/PL2764008T3/pl unknown
- 2012-10-05 ME MEP-2016-229A patent/ME02527B/me unknown
- 2012-10-05 ES ES12778664.8T patent/ES2593316T3/es active Active
- 2012-10-05 SG SG11201401282PA patent/SG11201401282PA/en unknown
- 2012-10-05 WO PCT/EP2012/069761 patent/WO2013050553A1/en active Application Filing
- 2012-10-05 RS RS20160859A patent/RS55231B1/sr unknown
- 2012-10-05 DK DK12778664.8T patent/DK2764008T3/en active
- 2012-10-05 AU AU2012320423A patent/AU2012320423C1/en active Active
- 2012-10-05 US US14/349,940 patent/US8987484B2/en active Active
- 2012-10-05 KR KR1020147007408A patent/KR102007874B1/ko active IP Right Grant
- 2012-10-05 MX MX2014003723A patent/MX348917B/es active IP Right Grant
- 2012-10-05 CA CA2847813A patent/CA2847813C/en active Active
- 2012-10-05 EA EA201490713A patent/EA024003B1/ru unknown
- 2012-10-05 BR BR112014008196A patent/BR112014008196B8/pt active IP Right Grant
- 2012-10-05 CN CN201280049319.2A patent/CN103890001B/zh active Active
- 2012-10-05 LT LTEP12778664.8T patent/LT2764008T/lt unknown
- 2012-10-05 SI SI201230705A patent/SI2764008T1/sl unknown
- 2012-10-05 PT PT127786648T patent/PT2764008T/pt unknown
- 2012-10-05 JP JP2014533925A patent/JP6196625B2/ja active Active
- 2012-10-05 HU HUE12778664A patent/HUE028963T2/en unknown
2014
- 2014-04-02 CL CL2014000802A patent/CL2014000802A1/es unknown
- 2014-05-05 IN IN841MUN2014 patent/IN2014MN00841A/en unknown
2015
- 2015-01-13 HK HK15100344.6A patent/HK1199882A1/zh unknown
2016
- 2016-10-05 HR HRP20161282TT patent/HRP20161282T1/hr unknown
- 2016-10-10 CY CY20161101001T patent/CY1118674T1/el unknown
- 2016-10-17 SM SM201600375T patent/SMT201600375B/it unknown

Also Published As

Publication number	Publication date
KR102007874B1 (ko)	2019-08-06
MX2014003723A (es)	2014-10-13
BR112014008196B1 (pt)	2020-10-20
HUE028963T2 (en)	2017-01-30
EP2764008A1 (en)	2014-08-13
CA2847813A1 (en)	2013-04-11
US20140243539A1 (en)	2014-08-28
SMT201600375B (it)	2017-01-10
SI2764008T1 (sl)	2016-10-28
NZ621973A (en)	2015-08-28
AU2012320423B2 (en)	2017-02-09
CN103890001A (zh)	2014-06-25
PL2764008T3 (pl)	2017-04-28
BR112014008196B8 (pt)	2020-12-15
JP6196625B2 (ja)	2017-09-13
CY1118674T1 (el)	2017-07-12
CA2847813C (en)	2018-12-11
KR20140083994A (ko)	2014-07-04
AU2012320423C1 (en)	2018-01-25
EA201490713A1 (ru)	2014-07-30
ES2593316T3 (es)	2016-12-07
EA024003B1 (ru)	2016-08-31
DK2764008T3 (en)	2016-11-07
LT2764008T (lt)	2016-11-10
ME02527B (me)	2017-02-20
RS55231B1 (sr)	2017-02-28
AU2012320423A1 (en)	2014-03-20
JP2014528438A (ja)	2014-10-27
HRP20161282T1 (hr)	2016-11-18
US8987484B2 (en)	2015-03-24
EP2764008B1 (en)	2016-08-17
CL2014000802A1 (es)	2014-11-14
MX348917B (es)	2017-07-04
CN103890001B (zh)	2016-05-04
WO2013050553A1 (en)	2013-04-11
IN2014MN00841A (zh)	2015-07-03
PT2764008T (pt)	2016-11-10
SG11201401282PA (en)	2014-05-29
BR112014008196A2 (pt)	2017-04-18

Publication	Publication Date	Title
HK1199882A1 (zh)	2015-07-24	用於製備雌四醇的方法
HRP20160692T1 (hr)	2016-08-12	Postupak za proizvodnju intermedijera estetrola
PT2744768T (pt)	2016-07-13	Processo para a produção de clínquer de ternesite
EP2699534A4 (en)	2015-01-14	PROCESS FOR PRODUCING TRANS-1233zd
SI2734536T1 (sl)	2017-01-31	Postopek za pripravo estetrola
ZA201308445B (en)	2015-07-29	Process for the production of estetrol intermediates
SG11201400939YA (en)	2014-07-30	Process for the preparation of methoxymelonal
HK1205097A1 (zh)	2015-12-11	用於生產甲基丁炔醇的方法
EP2797868A4 (en)	2015-08-12	PROCESS FOR PRODUCING HEXANEDIOLS
ZA201205844B (en)	2014-01-29	Process for the production of anhydrides
EP2740719A4 (en)	2015-03-11	PROCESS FOR THE PREPARATION OF A-FLUOROALDEHYDE
IL231645A0 (en)	2014-05-28	Process for the preparation of isoxazolyl-methoxy-nicotinic acids
PL2681199T3 (pl)	2019-03-29	Sposób wytwarzania (-)-hupercyny A
HUE044066T2 (hu)	2019-09-30	Eljárás metilén-difenil-diizocianát elõállítására
ZA201403104B (en)	2016-07-27	Process for the preparation of higher alcohols
SG11201403392UA (en)	2014-10-30	Process for the production of alcohols
PL2689069T3 (pl)	2017-04-28	Proces produkcji podsypki (balastu)
SG11201403380UA (en)	2014-09-26	Process for the production of alcohols
EP2700716A4 (en)	2015-04-29	PROCESS FOR THE PREPARATION OF L-CYSTONE
PL394420A1 (pl)	2012-10-08	Sposób wytwarzania dilauroilofluoresceiny
PL394378A1 (pl)	2012-10-08	Sposób otrzymywania E-2-amino-4-nitrostilbenów