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HK1030545A1 - Use of parathyroide hormone consisting of aminoacid sequence 1-34 of human parathyroid hormone for reducing the risk of both vertebral and non vertebral bone fracture - Google Patents

Use of parathyroide hormone consisting of aminoacid sequence 1-34 of human parathyroid hormone for reducing the risk of both vertebral and non vertebral bone fracture

Info

Publication number
HK1030545A1
HK1030545A1 HK01101056A HK01101056A HK1030545A1 HK 1030545 A1 HK1030545 A1 HK 1030545A1 HK 01101056 A HK01101056 A HK 01101056A HK 01101056 A HK01101056 A HK 01101056A HK 1030545 A1 HK1030545 A1 HK 1030545A1
Authority
HK
Hong Kong
Prior art keywords
vertebral
hormone
parathyroide
risk
reducing
Prior art date
Application number
HK01101056A
Other languages
English (en)
Inventor
Janet M Hock
Gregory A Gaich
Willard H Dere
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26792729&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1030545(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of HK1030545A1 publication Critical patent/HK1030545A1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/29Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/18Drugs for disorders of the endocrine system of the parathyroid hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Steroid Compounds (AREA)
  • Materials For Medical Uses (AREA)
HK01101056A 1998-08-19 2001-02-14 Use of parathyroide hormone consisting of aminoacid sequence 1-34 of human parathyroid hormone for reducing the risk of both vertebral and non vertebral bone fracture HK1030545A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9715198P 1998-08-19 1998-08-19
US9974698P 1998-09-10 1998-09-10
PCT/US1999/018961 WO2000010596A1 (fr) 1998-08-19 1999-08-19 Procede permettant d'augmenter la solidite et la rigidite osseuse et de reduire l'incidence ou la gravite d'une fracture

Publications (1)

Publication Number Publication Date
HK1030545A1 true HK1030545A1 (en) 2001-05-11

Family

ID=26792729

Family Applications (3)

Application Number Title Priority Date Filing Date
HK01101056A HK1030545A1 (en) 1998-08-19 2001-02-14 Use of parathyroide hormone consisting of aminoacid sequence 1-34 of human parathyroid hormone for reducing the risk of both vertebral and non vertebral bone fracture
HK07110798.6A HK1102496A1 (en) 1998-08-19 2007-10-04 Hpth(1-34) for use in preventing or reducing the incidence or severity of vertebral and / or non vertebral fracture in a male human
HK16100519.4A HK1212602A1 (zh) 1998-08-19 2016-01-18 增加骨的韌性和硬度和減少骨折的方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
HK07110798.6A HK1102496A1 (en) 1998-08-19 2007-10-04 Hpth(1-34) for use in preventing or reducing the incidence or severity of vertebral and / or non vertebral fracture in a male human
HK16100519.4A HK1212602A1 (zh) 1998-08-19 2016-01-18 增加骨的韌性和硬度和減少骨折的方法

Country Status (33)

Country Link
US (2) US6977077B1 (fr)
EP (3) EP1059933B1 (fr)
JP (5) JP2002523375A (fr)
KR (1) KR100454207B1 (fr)
CN (1) CN1205997C (fr)
AR (1) AR033639A1 (fr)
AT (1) ATE231000T1 (fr)
AU (1) AU746277B2 (fr)
BR (1) BR9909445A (fr)
CA (1) CA2325371C (fr)
CO (1) CO5130020A1 (fr)
CY (2) CY1113343T1 (fr)
CZ (1) CZ301017B6 (fr)
DE (2) DE69904918T2 (fr)
DK (4) DK1059933T3 (fr)
DZ (1) DZ2873A1 (fr)
EA (1) EA003362B1 (fr)
ES (4) ES2393200T3 (fr)
HK (3) HK1030545A1 (fr)
HR (1) HRP20000755A2 (fr)
HU (2) HU1200430D0 (fr)
ID (1) ID29039A (fr)
IL (2) IL138829A0 (fr)
MY (1) MY129227A (fr)
NO (2) NO323984B1 (fr)
NZ (1) NZ507056A (fr)
PE (1) PE20001089A1 (fr)
PL (1) PL201688B1 (fr)
PT (4) PT1059933E (fr)
TR (1) TR200003455T2 (fr)
TW (1) TW576747B (fr)
UA (1) UA72205C2 (fr)
WO (1) WO2000010596A1 (fr)

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US6770623B1 (en) 1997-12-09 2004-08-03 Eli Lilly And Company Stabilized teriparatide solutions
DZ2873A1 (fr) 1998-08-19 2003-12-15 Lilly Co Eli Procédé pour augmenter la dureté et la rigidité osseuse.
US20040033950A1 (en) * 2000-09-26 2004-02-19 Hock Janet M. Method of increasing bone toughness and stiffness and reducing fractures
EP1222465A1 (fr) * 1999-09-20 2002-07-17 Eli Lilly And Company Procede remettant d'effectuer le suivi du traitement avec une hormone parathyroidienne
US7247609B2 (en) 2001-12-18 2007-07-24 Universitat Zurich Growth factor modified protein matrices for tissue engineering
CA2472472A1 (fr) 2002-01-10 2003-07-24 Osteotrophin Llc Traitement des affections osseuses avec des medicaments anabolisants du squelette
US8088734B2 (en) 2003-01-21 2012-01-03 Unigene Laboratories Inc. Oral delivery of peptides
JP2007505883A (ja) * 2003-09-19 2007-03-15 ファイザー・プロダクツ・インク 2−アルキリデン−19−ノル−ビタミンd誘導体及び副甲状腺ホルモンの組合せを含んでなる医薬組成物及び方法
US20060189533A1 (en) * 2004-05-10 2006-08-24 Nastech Pharmaceutical Company Inc. Stable pharmaceutical dosage forms of teriparatide
JP2007537274A (ja) * 2004-05-10 2007-12-20 ナステック ファーマスーティカル カンパニー インク. 副甲状腺ホルモンの粘膜送達を増強するための組成物及び方法
US20060052305A1 (en) * 2004-05-10 2006-03-09 Nastech Pharmaceutical Company Inc. Method of treating osteoporosis using intranasal parathyroid hormone
US20060127320A1 (en) * 2004-05-10 2006-06-15 Nastech Pharmaceutical Company Inc. Method of delivering parathyroid hormone to a human
EP1744683B1 (fr) 2004-05-13 2016-03-16 Alza Corporation Appareil et procédé pour la délivrance transdermique d'agents à base d'hormone parathyroïde
US7648965B2 (en) 2004-05-14 2010-01-19 Unigene Laboratories Inc. Method for fostering bone formation and preservation
US20060069021A1 (en) * 2004-08-13 2006-03-30 Nastech Pharmaceutical Company Inc. Compositions and methods for intranasal administration of inactive analogs of PTH or inactivated preparations of PTH or PTH analogs
US8575101B2 (en) 2005-01-06 2013-11-05 Kuros Biosurgery Ag Supplemented matrices for the repair of bone fractures
WO2006073711A2 (fr) 2005-01-06 2006-07-13 Kuros Biosurgery Ag Traitement local des deficits osseux
CA2608016A1 (fr) * 2005-05-11 2006-11-23 Unigene Laboratories, Inc. Methode visant a ameliorer la formation et la preservation des os consistant a induire chirurgicalement une augmentation de l'activite des osteoblastes couplee aux effets de l'administration de la pthrp ou du cgrp
US20070173447A1 (en) * 2005-10-25 2007-07-26 Nastech Pharmaceutical Company Inc. Method for treating osteoporosis by intranasal delivery of teriparatide with an anti-resorptive agent
EP1945245A2 (fr) * 2005-11-10 2008-07-23 The Board of Control of Michigan Technological University Parathormone de l'ours noir et procedes d'utilisation de la parathormone de l'ours noir
US20080051332A1 (en) * 2005-11-18 2008-02-28 Nastech Pharmaceutical Company Inc. Method of modulating hematopoietic stem cells and treating hematologic diseases using intranasal parathyroid hormone
US20080119408A1 (en) * 2006-07-07 2008-05-22 Nastech Pharmaceutical Company Inc. Pth formulations for intranasal delivery
EP1961765A1 (fr) * 2006-12-08 2008-08-27 Zealand Pharma A/S Peptides PTH tronqués à formation cyclique
PT2136850E (pt) 2007-04-13 2012-04-27 Kuros Biosurgery Ag Selante tecidual polimérico
US20110137243A1 (en) * 2007-09-06 2011-06-09 Abbott Cardiovascular Systems Inc. Coating On A Balloon Device
EP2217260B1 (fr) * 2007-12-04 2016-11-09 Ben-Gurion University Of The Negev Research And Development Authority Matrices peptidiques amphiphiles pour le traitement de l'ostéoporose
CA2710798A1 (fr) 2007-12-28 2009-07-09 Kuros Biosurgery Ag Proteines hybrides du pdgf incorporees dans des mousses de fibrine
KR102335703B1 (ko) 2009-09-09 2021-12-07 아사히 가세이 파마 가부시키가이샤 1회당 100∼200 단위의 pth가 주 1회 투여되는 것을 특징으로 하는, pth 함유 골다공증 치료/예방제
BR112012013725A2 (pt) 2009-12-07 2017-01-10 Univ Michigan Tech paratormônio de urso preto e métodos de usar o paratormônio de uso preto.
US9295663B2 (en) 2010-07-14 2016-03-29 Abbott Cardiovascular Systems Inc. Drug coated balloon with in-situ formed drug containing microspheres
WO2012111852A1 (fr) * 2011-02-17 2012-08-23 帝人ファーマ株式会社 Agent thérapeutique pour fracture de corps vertébral et procédé pour évaluer celui-ci
ES2882852T3 (es) 2011-03-16 2021-12-02 Kuros Biosurgery Ag Formulación farmacéutica para la utilización en la fusión espinal
ES2761635T3 (es) 2011-06-07 2020-05-20 Asahi Kasei Pharma Corp Preparación liofilizada que contiene PTH de alta pureza y método para producirla
US9700485B2 (en) 2013-04-24 2017-07-11 Corning Incorporated Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
WO2017136195A1 (fr) 2016-02-01 2017-08-10 Eli Lilly And Company Composés de fusion parathormone-anticorps anti-rankl
US20190381341A1 (en) * 2017-02-01 2019-12-19 The Johns Hopkins University Parathyroid hormone and regeneration of degenerative discs disease
EP3685849A4 (fr) * 2017-09-22 2021-12-22 Asahi Kasei Pharma Corporation Composition pharmaceutique liquide contenant du tériparatide ayant une excellente stabilité
WO2020090174A1 (fr) 2018-10-29 2020-05-07 旭化成ファーマ株式会社 Méthode de prévention ou de traitement de l'ostéoporose caractérisée par l'administration de tériparatide ou d'un sel de celui-ci deux fois par semaine
EP4010360A1 (fr) 2019-08-09 2022-06-15 Flagship Pioneering Innovations VI, LLC Modulateurs du récepteur de l'hormone parathyroïdienne (pthr1)
GB2590692A (en) * 2019-12-24 2021-07-07 Corthotec Ltd Composition for improved bone fracture healing

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US4086196A (en) 1975-03-28 1978-04-25 Armour Pharmaceutical Company Parathyroid hormone
IL78342A (en) 1985-04-04 1991-06-10 Gen Hospital Corp Pharmaceutical composition for treatment of osteoporosis in humans comprising a parathyroid hormone or a fragment thereof
DE3935738A1 (de) 1989-10-27 1991-05-08 Forssmann Wolf Georg Arzneimittel, enthaltend das humane parathormon-fragment (1-37) als aktiven wirkstoff
US5208041A (en) 1991-05-23 1993-05-04 Allelix Biopharmaceuticals Inc. Essentially pure human parathyroid hormone
US5556940A (en) 1994-06-20 1996-09-17 National Research Council Of Canada Parathyroid hormone analogues for the treatment of osteoporosis
JPH0873376A (ja) * 1994-09-07 1996-03-19 Asahi Chem Ind Co Ltd 骨粗鬆症治療薬
US5747456A (en) * 1994-12-19 1998-05-05 Beth Israel Deaconess Medical Center Continuous low-dose administration of parathyroid hormone or its agonist
WO1996019246A1 (fr) * 1994-12-19 1996-06-27 Beth Israel Hospital Association Administration en continu de faibles doses d'hormone parathyroïdienne ou de son agoniste
CA2206657C (fr) * 1994-12-22 2009-05-19 Astra Aktiebolag Preparation therapeutique a inhaler contenant de l'hormone parathyroidienne, hpt
JPH08310965A (ja) * 1995-05-16 1996-11-26 Chugai Pharmaceut Co Ltd 骨癒合促進剤
RU2224539C2 (ru) * 1997-09-09 2004-02-27 Ф.Хоффманн-Ля Рош Аг Заживление переломов с помощью аналогов пептида, подобного паратироидному гормону (ртнrр)
MY120063A (en) 1997-12-09 2005-08-30 Lilly Co Eli Stabilized teriparatide solutions
US20040033950A1 (en) * 2000-09-26 2004-02-19 Hock Janet M. Method of increasing bone toughness and stiffness and reducing fractures
DZ2873A1 (fr) 1998-08-19 2003-12-15 Lilly Co Eli Procédé pour augmenter la dureté et la rigidité osseuse.
US6907597B1 (en) 2000-10-13 2005-06-14 Ati International Srl Method and apparatus for constructing an executable program in memory
US6967759B2 (en) 2001-12-31 2005-11-22 Texas Instruments Incorporated Pulse width modulation sequence generation
JP5796714B2 (ja) 2012-01-13 2015-10-21 株式会社リコー 定着装置及び画像形成装置
EP2949301B1 (fr) 2014-05-27 2018-04-18 The Procter and Gamble Company Noyau absorbant avec des zones de matériau absorbant incurvées et droites

Also Published As

Publication number Publication date
KR20010072763A (ko) 2001-07-31
JP6177718B2 (ja) 2017-08-09
AR033639A1 (es) 2004-01-07
ES2393200T3 (es) 2012-12-19
PT1059933E (pt) 2003-06-30
DZ2873A1 (fr) 2003-12-15
CA2325371A1 (fr) 2000-03-02
DK2907522T1 (da) 2015-10-19
CO5130020A1 (es) 2002-02-27
CZ20004134A3 (cs) 2001-08-15
ES2621653T3 (es) 2017-07-04
JP2017190332A (ja) 2017-10-19
TR200003455T2 (tr) 2001-06-21
DE15152726T1 (de) 2015-12-10
CY1113343T1 (el) 2016-06-22
TW576747B (en) 2004-02-21
DK1059933T3 (da) 2003-04-07
ES2549551T3 (es) 2017-11-27
KR100454207B1 (ko) 2004-10-26
EP2907522B1 (fr) 2017-08-02
NO20072983L (no) 2000-11-24
PE20001089A1 (es) 2000-11-04
IL138829A0 (en) 2001-10-31
HU1200430D0 (hu) 2001-11-28
HUP0101594A2 (hu) 2001-11-28
DK2266598T3 (en) 2017-05-15
AU5575099A (en) 2000-03-14
PL201688B1 (pl) 2009-04-30
CY1119552T1 (el) 2018-03-07
JP2011021035A (ja) 2011-02-03
NZ507056A (en) 2003-10-31
US7163684B2 (en) 2007-01-16
HUP0101594A3 (en) 2002-01-28
NO20005947L (no) 2000-11-24
NO20005947D0 (no) 2000-11-24
PL343595A1 (en) 2001-08-27
US6977077B1 (en) 2005-12-20
UA72205C2 (uk) 2005-02-15
HU230697B1 (hu) 2017-09-28
NO323984B1 (no) 2007-07-30
BR9909445A (pt) 2000-12-12
PT1769804E (pt) 2012-11-13
AU746277B2 (en) 2002-04-18
CN1205997C (zh) 2005-06-15
DK2907522T3 (en) 2017-10-23
EA200001015A1 (ru) 2001-02-26
PT2266598T (pt) 2017-05-02
HRP20000755A2 (en) 2001-02-28
WO2000010596A1 (fr) 2000-03-02
EP1059933A1 (fr) 2000-12-20
EP2907522A1 (fr) 2015-08-19
HK1212602A1 (zh) 2016-06-17
ATE231000T1 (de) 2003-02-15
EP1059933B1 (fr) 2003-01-15
MY129227A (en) 2007-03-30
EA003362B1 (ru) 2003-04-24
CN1308545A (zh) 2001-08-15
JP2015028065A (ja) 2015-02-12
IL138829A (en) 2011-01-31
JP2002523375A (ja) 2002-07-30
ID29039A (id) 2001-07-26
JP2014139220A (ja) 2014-07-31
DK1769804T3 (da) 2012-10-15
EP2266598A1 (fr) 2010-12-29
CA2325371C (fr) 2004-08-17
US20050197294A1 (en) 2005-09-08
CZ301017B6 (cs) 2009-10-14
PT2907522T (pt) 2017-10-23
DE69904918T2 (de) 2003-11-13
DE69904918D1 (de) 2003-02-20
HK1102496A1 (en) 2007-11-23
ES2549551T1 (es) 2015-10-29
ES2190244T3 (es) 2003-07-16
EP2266598B1 (fr) 2017-02-22

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