HK1065949A1 - Indolylalkylamine derivatives as 5-hydroxytryptamine-6 ligands - Google Patents
Indolylalkylamine derivatives as 5-hydroxytryptamine-6 ligandsInfo
- Publication number
- HK1065949A1 HK1065949A1 HK04108844A HK04108844A HK1065949A1 HK 1065949 A1 HK1065949 A1 HK 1065949A1 HK 04108844 A HK04108844 A HK 04108844A HK 04108844 A HK04108844 A HK 04108844A HK 1065949 A1 HK1065949 A1 HK 1065949A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- hydroxytryptamine
- ligands
- indolylalkylamine
- derivatives
- indolylalkylamine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US34290701P | 2001-12-20 | 2001-12-20 | |
PCT/US2002/040217 WO2003053433A1 (en) | 2001-12-20 | 2002-12-17 | Indolylalkylamine derivatives as 5-hydroxytryptamine-6 ligands |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1065949A1 true HK1065949A1 (en) | 2005-03-11 |
Family
ID=23343804
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK04108844A HK1065949A1 (en) | 2001-12-20 | 2004-11-10 | Indolylalkylamine derivatives as 5-hydroxytryptamine-6 ligands |
Country Status (30)
Country | Link |
---|---|
US (2) | US6770642B2 (zh) |
EP (1) | EP1455779B1 (zh) |
JP (1) | JP4335684B2 (zh) |
KR (1) | KR100985140B1 (zh) |
CN (1) | CN1309385C (zh) |
AR (1) | AR037906A1 (zh) |
AT (1) | ATE335477T1 (zh) |
AU (1) | AU2002357270B2 (zh) |
BR (1) | BR0215222A (zh) |
CA (1) | CA2470863C (zh) |
CO (1) | CO5590924A2 (zh) |
CY (1) | CY1105705T1 (zh) |
DE (1) | DE60213856T2 (zh) |
DK (1) | DK1455779T3 (zh) |
EC (1) | ECSP045156A (zh) |
ES (1) | ES2269827T3 (zh) |
HK (1) | HK1065949A1 (zh) |
HU (1) | HUP0402640A3 (zh) |
IL (1) | IL162243A0 (zh) |
MX (1) | MXPA04005889A (zh) |
NO (1) | NO330338B1 (zh) |
NZ (1) | NZ533666A (zh) |
PL (1) | PL210413B1 (zh) |
PT (1) | PT1455779E (zh) |
RU (1) | RU2309157C2 (zh) |
SI (1) | SI1455779T1 (zh) |
TW (1) | TWI254705B (zh) |
UA (1) | UA78536C2 (zh) |
WO (1) | WO2003053433A1 (zh) |
ZA (1) | ZA200405731B (zh) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7026515B2 (en) * | 2000-11-09 | 2006-04-11 | Mitsui Chemicals, Inc. | Optically active amine derivatives and preparation process therefor |
TW200301251A (en) * | 2001-12-20 | 2003-07-01 | Wyeth Corp | Azaindolylalkylamine derivatives as 5-hydroxytryptamine-6 ligands |
EP1654258A1 (en) * | 2003-07-23 | 2006-05-10 | Wyeth | Sulfonyldihydro- benzimidazolone compounds as 5-hydroxytryptamine-6 ligands |
US20050032873A1 (en) * | 2003-07-30 | 2005-02-10 | Wyeth | 3-Amino chroman and 2-amino tetralin derivatives |
MXPA06000957A (es) * | 2003-07-31 | 2006-03-30 | Wyeth Corp | Compuestos de n-sulfonil heterociclopirrolilalquilamina como ligandos de 5-hidroxitriptamina-6. |
KR20060054410A (ko) * | 2003-08-01 | 2006-05-22 | 제네랩스 테크놀로지스, 인코포레이티드 | 플라비비리다에에 대한 2고리 이미다졸 유도체 |
AU2004312229B2 (en) * | 2004-01-02 | 2010-05-20 | Suven Life Sciences Limited | Novel Indeno[2,1a]indenes and isoindolo[2,1-a]indoles |
PE20060303A1 (es) * | 2004-06-23 | 2006-05-19 | Wyeth Corp | Metabolitos de indolilalquilamina como ligandos de 5-hidroxitriptamina-6 |
JP2008523146A (ja) * | 2004-12-14 | 2008-07-03 | ワイス | 神経変性障害の処置および予防のための5−ht6アゴニストの使用 |
MX2007008587A (es) * | 2005-01-14 | 2007-09-07 | Genelabs Tech Inc | Derivados de indol para tratamiento de infecciones virales. |
EP1953153A1 (en) * | 2007-01-31 | 2008-08-06 | Laboratorios del Dr. Esteve S.A. | Heterocyclyl-substituted sulfonamides for the treatment of cognitive or food ingestion related disorders |
AU2008256859A1 (en) * | 2007-05-24 | 2008-12-04 | Memory Pharmaceuticals Corporation | 4' substituted compounds having 5-HT6 receptor affinity |
ES2359170T3 (es) * | 2007-07-19 | 2011-05-19 | Laboratorios Del Dr. Esteve S.A. | Compuestos tetrahidro-quinolín-sulfonamida sustituidos, su preparación y uso como medicamentos. |
EP2053052A1 (en) * | 2007-10-23 | 2009-04-29 | Laboratorios del Dr. Esteve S.A. | Process for the preparation of 6-substituted imidazo[2,1-b]thiazole-5-sulfonyl halide |
CA2706651A1 (en) * | 2007-12-04 | 2009-06-11 | Merck Sharp & Dohme Corp. | Tryptamine sulfonamides as 5-ht6 antagonists |
EP2236511A4 (en) | 2007-12-21 | 2011-04-13 | Alla Chem Llc | LIGANDS OF ALPHA ADRENOCEPTORS AND OF DOPAMINE, HISTAMIN, IMIDAZOLIN AND SEROTONIN RECEPTORS AND THEIR APPLICATION THEREOF |
US20100016297A1 (en) * | 2008-06-24 | 2010-01-21 | Memory Pharmaceuticals Corporation | Alkyl-substituted 3' compounds having 5-ht6 receptor affinity |
US20100022581A1 (en) * | 2008-07-02 | 2010-01-28 | Memory Pharmaceuticals Corporation | Pyrrolidine-substituted azaindole compounds having 5-ht6 receptor affinity |
US20100029629A1 (en) * | 2008-07-25 | 2010-02-04 | Memory Pharmaceuticals Corporation | Acyclic compounds having 5-ht6 receptor affinity |
US20100056531A1 (en) * | 2008-08-22 | 2010-03-04 | Memory Pharmaceuticals Corporation | Alkyl-substituted 3' compounds having 5-ht6 receptor affinity |
WO2015090233A1 (en) | 2013-12-20 | 2015-06-25 | Sunshine Lake Pharma Co., Ltd. | Aromatic heterocyclic compounds and their application in pharmaceuticals |
CA2959505A1 (en) | 2014-08-29 | 2016-03-03 | Chdi Foundation, Inc. | Probes for imaging huntingtin protein |
ES2898965T3 (es) | 2014-08-29 | 2022-03-09 | Chdi Foundation Inc | Sondas de formación de imágenes de la proteína Huntingtina |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5545644A (en) | 1990-10-15 | 1996-08-13 | Pfizer Inc. | Indole derivatives |
US6194410B1 (en) * | 1998-03-11 | 2001-02-27 | Hoffman-La Roche Inc. | Pyrazolopyrimidine and pyrazolines and process for preparation thereof |
US6133287A (en) | 1998-03-24 | 2000-10-17 | Allelix Biopharmaceuticals Inc. | Piperidine-indole compounds having 5-HT6 affinity |
GB9820113D0 (en) * | 1998-09-15 | 1998-11-11 | Merck Sharp & Dohme | Therapeutic agents |
US6403808B1 (en) | 1999-12-10 | 2002-06-11 | Virginia Commonwealth University | Selective 5-HT6 receptor ligands |
WO2001012629A1 (en) * | 1999-08-12 | 2001-02-22 | Nps Allelix Corp. | Azaindoles having serotonin receptor affinity |
AU1542201A (en) * | 1999-11-05 | 2001-05-14 | Nps Allelix Corp. | Compounds having 5-HT6 receptor antagonist activity |
WO2001034146A1 (en) * | 1999-11-08 | 2001-05-17 | Smithkline Beecham Corporation | Novel anti-infectives |
-
2002
- 2002-12-17 ES ES02805601T patent/ES2269827T3/es not_active Expired - Lifetime
- 2002-12-17 NZ NZ533666A patent/NZ533666A/xx not_active IP Right Cessation
- 2002-12-17 AT AT02805601T patent/ATE335477T1/de active
- 2002-12-17 JP JP2003554190A patent/JP4335684B2/ja not_active Expired - Fee Related
- 2002-12-17 WO PCT/US2002/040217 patent/WO2003053433A1/en active IP Right Grant
- 2002-12-17 RU RU2004122129/04A patent/RU2309157C2/ru not_active IP Right Cessation
- 2002-12-17 HU HU0402640A patent/HUP0402640A3/hu unknown
- 2002-12-17 CN CNB028281721A patent/CN1309385C/zh not_active Expired - Fee Related
- 2002-12-17 AU AU2002357270A patent/AU2002357270B2/en not_active Ceased
- 2002-12-17 PL PL370711A patent/PL210413B1/pl not_active IP Right Cessation
- 2002-12-17 SI SI200230401T patent/SI1455779T1/sl unknown
- 2002-12-17 DE DE60213856T patent/DE60213856T2/de not_active Expired - Lifetime
- 2002-12-17 EP EP02805601A patent/EP1455779B1/en not_active Expired - Lifetime
- 2002-12-17 DK DK02805601T patent/DK1455779T3/da active
- 2002-12-17 PT PT02805601T patent/PT1455779E/pt unknown
- 2002-12-17 IL IL16224302A patent/IL162243A0/xx unknown
- 2002-12-17 BR BR0215222-3A patent/BR0215222A/pt not_active Application Discontinuation
- 2002-12-17 CA CA2470863A patent/CA2470863C/en not_active Expired - Fee Related
- 2002-12-17 KR KR1020047009606A patent/KR100985140B1/ko not_active IP Right Cessation
- 2002-12-17 UA UA20040705919A patent/UA78536C2/uk unknown
- 2002-12-17 MX MXPA04005889A patent/MXPA04005889A/es active IP Right Grant
- 2002-12-18 TW TW091136490A patent/TWI254705B/zh active
- 2002-12-18 AR ARP020104951A patent/AR037906A1/es unknown
- 2002-12-19 US US10/323,369 patent/US6770642B2/en not_active Expired - Fee Related
-
2004
- 2004-04-20 US US10/828,014 patent/US7022701B2/en not_active Expired - Fee Related
- 2004-06-15 CO CO04055771A patent/CO5590924A2/es not_active Application Discontinuation
- 2004-06-16 EC EC2004005156A patent/ECSP045156A/es unknown
- 2004-07-19 NO NO20043100A patent/NO330338B1/no not_active IP Right Cessation
- 2004-07-19 ZA ZA200405731A patent/ZA200405731B/en unknown
- 2004-11-10 HK HK04108844A patent/HK1065949A1/xx not_active IP Right Cessation
-
2006
- 2006-10-13 CY CY20061101474T patent/CY1105705T1/el unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL157059A0 (en) | 1-aryl-or 1-alkylsulfonylbenzazole derivatives as 5-hydroxytryptamine-6 ligands | |
IL158445A0 (en) | Heterocyclyloxy-, -thioxy-and-aminobenzazole derivatives as 5-hydroxytryptamine-6 ligands | |
PL370890A1 (en) | Azaindolylalkylamine derivatives as 5-hydroxytryptamine-6 ligands | |
ZA200500437B (en) | 1-heterocyclyalkyl-3-sulfonazaindole or -azaindazole derivatives as 5-hydroxytryptamine-6 ligands | |
IL155443A0 (en) | 1- aryl- or 1-alkylsulfonyl-heterocyclylbenzazoles as 5-hydroxytryptamine-6 ligands | |
ZA200500435B (en) | 1-heterocyclyalkyl-3-sulfonylindole or -indazole derivatves as 5-hydroxytryptamine-6 ligands | |
HK1066218A1 (en) | Qunazoline derivatives as antitumor agents | |
HK1065949A1 (en) | Indolylalkylamine derivatives as 5-hydroxytryptamine-6 ligands | |
IL156517A0 (en) | Heterocyclindazole and azaindazole compounds as 5-hydroxytryptamine-6 ligands | |
HK1068608A1 (en) | 3-Substituted-4-pyrimidone derivatives | |
ZA200506416B (en) | Heterocyclyl-3-sulfonylindazoles as 5-hydroxytryptamine-6 ligands | |
IL156518A0 (en) | Heteocyclylalkylindole or-azaindole compounds as 5-hydroxytryptamine-6 ligands | |
IL158448A0 (en) | Heterocyclylalkoxy- alkylthio-and-alkylaminobenzazole derivatives as 5-hydroxytryptamine-6 ligands | |
HUP0303186A3 (en) | 4-aminobenzopyran derivatives | |
HUP0401949A3 (en) | 4-imidazolin-2-one derivatives | |
HUP0500026A3 (en) | N-heteroarylnicotinamide derivatives | |
IL159064A0 (en) | New phenylalkyloxy- phenyl derivatives | |
AU2003209114A1 (en) | Pyrrolylalkylidene-hydrazinecarboximidamide derivatives as 5-hydroxytryptamine-6 ligands | |
EP1364954A4 (en) | Dicarba closo DODECARBORANDERIVATE | |
GB0115841D0 (en) | Ligand | |
AU2002334722A1 (en) | Chroman derivatives as 5-hydroxytryptamine-6 ligands | |
SI1427709T1 (sl) | 3-substituirani-4-pirimidonski derivati |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20131217 |