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HK1054377A1 - 3-(Heteroaryl acetamido)-2-oxo-azetidine-1-sulfonic acids derivatives as antibacterial agents - Google Patents

3-(Heteroaryl acetamido)-2-oxo-azetidine-1-sulfonic acids derivatives as antibacterial agents

Info

Publication number
HK1054377A1
HK1054377A1 HK03106287A HK03106287A HK1054377A1 HK 1054377 A1 HK1054377 A1 HK 1054377A1 HK 03106287 A HK03106287 A HK 03106287A HK 03106287 A HK03106287 A HK 03106287A HK 1054377 A1 HK1054377 A1 HK 1054377A1
Authority
HK
Hong Kong
Prior art keywords
azetidine
oxo
sulfonic acids
antibacterial agents
acids derivatives
Prior art date
Application number
HK03106287A
Other languages
English (en)
Inventor
Ronald George Micetich
Samarendra Nath Maiti
Charles Fiakpui
George Thomas
Reddy Andhe V Narender
Sameeh M Salama
Rajeshwar Singh
Original Assignee
Pantherix Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pantherix Ltd filed Critical Pantherix Ltd
Publication of HK1054377A1 publication Critical patent/HK1054377A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK03106287A 2000-09-14 2003-09-03 3-(Heteroaryl acetamido)-2-oxo-azetidine-1-sulfonic acids derivatives as antibacterial agents HK1054377A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23261700P 2000-09-14 2000-09-14
PCT/IB2001/002115 WO2002022613A1 (en) 2000-09-14 2001-09-14 3-(heteroaryl acetamido)-2-oxo-azetidine-1-sulfonic acids derivatives as antibacterial agents

Publications (1)

Publication Number Publication Date
HK1054377A1 true HK1054377A1 (en) 2003-11-28

Family

ID=22873854

Family Applications (1)

Application Number Title Priority Date Filing Date
HK03106287A HK1054377A1 (en) 2000-09-14 2003-09-03 3-(Heteroaryl acetamido)-2-oxo-azetidine-1-sulfonic acids derivatives as antibacterial agents

Country Status (23)

Country Link
US (1) US6916803B2 (ko)
EP (1) EP1322648B1 (ko)
JP (1) JP2004509122A (ko)
KR (1) KR100854810B1 (ko)
CN (1) CN1189469C (ko)
AT (1) ATE298750T1 (ko)
AU (2) AU1261402A (ko)
BR (1) BR0113861A (ko)
CA (1) CA2422375C (ko)
CZ (1) CZ304586B6 (ko)
DE (1) DE60111757T2 (ko)
DK (1) DK1322648T3 (ko)
ES (1) ES2244666T3 (ko)
HK (1) HK1054377A1 (ko)
HU (1) HUP0301025A3 (ko)
IL (2) IL154593A0 (ko)
NO (1) NO324946B1 (ko)
NZ (1) NZ524292A (ko)
PL (1) PL218196B1 (ko)
PT (1) PT1322648E (ko)
SK (1) SK2462003A3 (ko)
WO (1) WO2002022613A1 (ko)
ZA (1) ZA200302085B (ko)

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PT2308874E (pt) * 2005-12-07 2013-04-26 Basilea Pharmaceutica Ag Monobactamas ligadas por pontes, úteis como inibidores de beta-lactamase
BRPI0809147A2 (pt) 2007-03-23 2014-08-26 Basilea Pharmaceutica Ag Medicamentos combinados para tratamento de infecções bacterianas
WO2009114921A1 (en) * 2008-03-17 2009-09-24 Dmitrienko Gary I INHIBITORS OF CLASS B AND CLASS D β-LACTAMASES
RU2599791C2 (ru) 2010-08-10 2016-10-20 Ремпекс Фармасьютикэлз, Инч. Циклические бороновые кислотно-эфирные производные и их использование в терапии
US9012491B2 (en) 2011-08-31 2015-04-21 Rempex Pharmaceuticals, Inc. Heterocyclic boronic acid ester derivatives and therapeutic uses thereof
UY34585A (es) 2012-01-24 2013-09-02 Aicuris Gmbh & Co Kg Compuestos b-lactámicos sustituidos con amidina, su preparación y uso
US9156858B2 (en) 2012-05-23 2015-10-13 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
US10561675B2 (en) 2012-06-06 2020-02-18 Rempex Pharmaceuticals, Inc. Cyclic boronic acid ester derivatives and therapeutic uses thereof
CN102757405B (zh) * 2012-07-25 2014-04-16 山东理工大学 含噻二唑的香兰素衍生物、其制备方法及其用途
BR112015016002A2 (pt) 2013-01-04 2017-07-11 Rempex Pharmaceuticals Inc compostos, composições farmacêuticas, complexos químicos e respectivos usos e método para tratar ou prevenir infecção bacteriana
CN104994844A (zh) 2013-01-04 2015-10-21 莱姆派克斯制药公司 硼酸衍生物及其治疗用途
US9241947B2 (en) 2013-01-04 2016-01-26 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
US9101638B2 (en) 2013-01-04 2015-08-11 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
LT3140310T (lt) 2014-05-05 2019-11-25 Rempex Pharmaceuticals Inc Boronato druskų sintezė ir jų panaudojimas
WO2015171398A1 (en) 2014-05-05 2015-11-12 Rempex Pharmaceuticals, Inc. Salts and polymorphs of cyclic boronic acid ester derivatives and therapeutic uses thereof
JP6672176B2 (ja) 2014-05-19 2020-03-25 レンペックス・ファーマシューティカルズ・インコーポレイテッド ボロン酸誘導体およびその治療的使用
JP6700203B2 (ja) 2014-07-01 2020-05-27 レンペックス・ファーマシューティカルズ・インコーポレイテッド ボロン酸誘導体およびその治療的使用
WO2016081297A1 (en) 2014-11-18 2016-05-26 Rempex Pharmaceuticals, Inc. Cyclic boronic acid ester derivatives and therapeutic uses thereof
ES2761778T3 (es) 2014-12-19 2020-05-21 Rempex Pharmaceuticals Inc Aparato y proceso de flujo continuo para la producción de derivados de ácido borónico
US20180051041A1 (en) 2015-03-17 2018-02-22 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
ES2894251T3 (es) 2016-06-30 2022-02-14 Qpex Biopharma Inc Derivados de ácido borónico y usos terapéuticos de los mismos
CN107641119B (zh) * 2016-07-21 2019-11-08 中国科学院上海药物研究所 单环β-内酰胺-铁载体轭合物及其制备方法和用途
WO2018065636A1 (en) 2016-12-21 2018-04-12 Aicuris Anti-Infective Cures Gmbh COMBINATION THERAPY WITH AMIDINE SUBSTITUTED ß-LACTAM COMPOUNDS AND ß-LACTAMASE INHIBITORS FOR INFECTIONS WITH ANTIBIOTIC RESISTANT BACTERIAL STRAINS
JP7377545B2 (ja) 2017-10-11 2023-11-10 キューペックス バイオファーマ, インコーポレイテッド ボロン酸誘導体およびその合成
CN111511737B (zh) 2018-01-29 2022-10-18 南京明德新药研发有限公司 用于治疗细菌感染的单环β-内酰胺化合物
CA3097127A1 (en) 2018-04-20 2019-10-24 Qpex Biopharma, Inc. Boronic acid derivatives and therapeutic uses thereof
JP7179185B2 (ja) 2018-12-18 2022-11-28 メッドシャイン ディスカバリー インコーポレイテッド 医薬の製造おける単環式β-ラクタム化合物の使用
SI25892A (sl) * 2019-09-05 2021-03-31 Gorenje Gospodinjski Aparati, D.O.O. Pralni stroj, ki se polni s sprednje strani, z električnim svetlobnim telesom
JP2022548067A (ja) 2019-09-11 2022-11-16 テンノア・セラピューティクス・(スージョウ)・リミテッド 細菌感染症を治療するためのペナム誘導体
KR20220084398A (ko) 2019-11-22 2022-06-21 쑤저우 얼예 파마슈티칼 컴퍼니 리미티드 설포닐우레아 고리 치환 모노시클릭 β-락탐계 항생제
EP4079305A4 (en) 2019-12-19 2024-01-10 Shenzhen Optimum Biological Technology Co., Ltd APPLICATION OF A COMPOUND IN THE PREPARATION OF DRUG
CN113754651B (zh) * 2020-06-02 2023-04-18 中国医学科学院医药生物技术研究所 一种β-内酰胺化合物、其用途及其制备方法
JP2024532211A (ja) * 2021-08-20 2024-09-05 ユニバーシティ・オブ・ノートル・ダム・デュ・ラック 単環式β-ラクタムとシデロフォア模倣体との結合体
CN115304594B (zh) 2022-10-12 2023-02-14 苏州二叶制药有限公司 磺酰脲环取代的化合物的盐型及其晶型

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US4632985A (en) 1985-06-03 1986-12-30 E. R. Squibb & Sons, Inc. 3-acylamino-2-oxo-1-azetidinesulfonic acids
GB8810396D0 (en) 1988-05-03 1988-06-08 Glaxo Group Ltd Chemical process
US5112968A (en) * 1989-07-28 1992-05-12 E. R. Squibb & Sons, Inc. Monobactam hydrazide derivatives
US5250691A (en) * 1991-09-09 1993-10-05 E. R. Squibb & Sons, Inc. Heteroaryl derivatives of monocyclic beta-lactam antibiotics
US5888998A (en) * 1997-04-24 1999-03-30 Synphar Laboratories, Inc. 2-oxo-1-azetidine sulfonic acid derivatives as potent β-lactamase inhibitors
US5994340A (en) 1997-08-29 1999-11-30 Synphar Laboratories, Inc. Azetidinone derivatives as β-lactamase inhibitors

Also Published As

Publication number Publication date
DK1322648T3 (da) 2005-10-31
HUP0301025A2 (hu) 2004-04-28
JP2004509122A (ja) 2004-03-25
CZ2003606A3 (cs) 2003-08-13
NO20031162L (no) 2003-03-13
DE60111757D1 (de) 2005-08-04
ES2244666T3 (es) 2005-12-16
DE60111757T2 (de) 2006-04-27
CA2422375A1 (en) 2002-03-21
CA2422375C (en) 2011-03-15
US6916803B2 (en) 2005-07-12
PL218196B1 (pl) 2014-10-31
PL360537A1 (en) 2004-09-06
BR0113861A (pt) 2004-01-27
AU2002212614B2 (en) 2006-12-07
ZA200302085B (en) 2004-03-15
NZ524292A (en) 2004-09-24
NO20031162D0 (no) 2003-03-13
SK2462003A3 (en) 2003-09-11
KR20030039369A (ko) 2003-05-17
IL154593A0 (en) 2003-09-17
WO2002022613A1 (en) 2002-03-21
CN1458932A (zh) 2003-11-26
CN1189469C (zh) 2005-02-16
IL154593A (en) 2008-06-05
EP1322648A1 (en) 2003-07-02
ATE298750T1 (de) 2005-07-15
EP1322648B1 (en) 2005-06-29
NO324946B1 (no) 2008-01-07
CZ304586B6 (cs) 2014-07-23
KR100854810B1 (ko) 2008-08-27
HUP0301025A3 (en) 2009-03-30
US20040019203A1 (en) 2004-01-29
PT1322648E (pt) 2005-11-30
AU1261402A (en) 2002-03-26

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20110914