HK1050894A1 - Aryl fused azapolycyclic compounds - Google Patents

Aryl fused azapolycyclic compounds

Info

Publication number: HK1050894A1
Authority: HK; Hong Kong
Prior art keywords: compounds; aryl fused; fused azapolycyclic; azapolycyclic compounds; aryl
Prior art date: 2000-02-25

Application number

HK03103024A

Other languages

English (en)

Inventor

Paige Roanne Palmer Brooks

Jotham Wadsworth Coe

Original Assignee

Pfizer Prod Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-02-25

Filing date

2003-04-29

Publication date

2003-07-11

2003-04-29 Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc

2003-07-11 Publication of HK1050894A1 publication Critical patent/HK1050894A1/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/08—Bridged systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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- A61P25/08—Antiepileptics; Anticonvulsants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/24—Camphidines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Addiction (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Psychology (AREA)
Obesity (AREA)
Anesthesiology (AREA)
Hospice & Palliative Care (AREA)
Hematology (AREA)
Diabetes (AREA)
Child & Adolescent Psychology (AREA)
Rheumatology (AREA)
Toxicology (AREA)
Nutrition Science (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

HK03103024A 2000-02-25 2003-04-29 Aryl fused azapolycyclic compounds HK1050894A1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US09/514,002 US6605610B1 (en)	1997-12-31	2000-02-25	Aryl fused azapolycyclic compounds
PCT/IB2001/000153 WO2001062736A1 (en)	2000-02-25	2001-02-08	Aryl fused azapolycyclic compounds

Publications (1)

Publication Number	Publication Date
HK1050894A1 true HK1050894A1 (en)	2003-07-11

Family

ID=24045406

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HK03103024A HK1050894A1 (en)	2000-02-25	2003-04-29	Aryl fused azapolycyclic compounds

Country Status (40)

Country	Link
US (3)	US6605610B1 (xx)
EP (2)	EP1619192B1 (xx)
JP (1)	JP2003524002A (xx)
KR (1)	KR100537976B1 (xx)
CN (1)	CN1263745C (xx)
AP (1)	AP1860A (xx)
AT (2)	ATE328872T1 (xx)
AU (2)	AU784081B2 (xx)
BG (1)	BG65891B1 (xx)
BR (1)	BR0108610A (xx)
CA (1)	CA2401229C (xx)
CR (1)	CR6726A (xx)
CU (1)	CU23148A3 (xx)
CY (1)	CY1105301T1 (xx)
CZ (1)	CZ303203B6 (xx)
DE (2)	DE60120366T2 (xx)
DK (2)	DK1619192T3 (xx)
DZ (1)	DZ3328A1 (xx)
EA (1)	EA005316B1 (xx)
EE (1)	EE200200475A (xx)
ES (2)	ES2263640T3 (xx)
GE (1)	GEP20053454B (xx)
HK (1)	HK1050894A1 (xx)
HR (1)	HRP20020700A2 (xx)
HU (1)	HU229482B1 (xx)
IL (2)	IL150639A0 (xx)
IS (1)	IS2293B (xx)
MA (1)	MA26875A1 (xx)
MX (1)	MXPA02008311A (xx)
NO (1)	NO323608B1 (xx)
NZ (1)	NZ519973A (xx)
OA (1)	OA12181A (xx)
PL (1)	PL365163A1 (xx)
PT (1)	PT1259489E (xx)
RS (1)	RS51123B (xx)
SI (1)	SI1259489T1 (xx)
SK (1)	SK12042002A3 (xx)
UA (1)	UA74813C2 (xx)
WO (1)	WO2001062736A1 (xx)
ZA (1)	ZA200206768B (xx)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ME00459B (me) *	1997-12-31	2011-10-10	Pfizer Prod Inc	Aril fuzirana azapoliciklična jedinjenja
BR0208992A (pt) *	2001-04-20	2004-04-27	Pfizer Prod Inc	Processo para a preparação de indenos 1,3-substituìdos e compostos azapolicìclicos fundidos com arila
WO2003037329A1 (en) *	2001-10-31	2003-05-08	Pfizer Products Inc.	Nicotinic acetylcholine receptor agonists in the treatment of restless legs syndrome
CN1864663A (zh) *	2001-11-30	2006-11-22	辉瑞产品公司	5,7,14－三氮杂四环[10.3.1.0(2,11).0(4,9)]－十六碳－2(11)3,5,7,9－五烯的药物组合物
EP1451202B1 (en) *	2001-11-30	2008-08-20	Pfizer Products Inc.	Aryl fused azapolycyclic compounds
WO2004009116A2 (en)	2002-07-18	2004-01-29	Cytos Biotechnology Ag	Hapten-carrier conjugates comprising virus like particles and uses thereof
EP1554041B1 (en) *	2002-10-22	2012-05-23	EMD Millipore Corporation	Multi-sided immersion formation of composite structures and method
WO2004048318A1 (en) *	2002-11-25	2004-06-10	Pfizer Products Inc.	Improved process for the preparation of 1,3-substituted indenes
MXPA05007565A (es) *	2003-01-15	2005-09-21	Pfizer Prod Inc	Procedimiento mejorado de preparacion de lactamas policiclicas fusionadas con arilos.
WO2004103372A1 (en) *	2003-05-20	2004-12-02	Pfizer Products Inc.	Pharmaceutical compositions of varenicline
PL378491A1 (pl) *	2003-06-04	2006-05-02	Pfizer Products Inc.	Sposób wytwarzania podstawionych chinoksalin z dianiliny i z 2,3-dihydroksy-1,4-dioksanu
MXPA06000892A (es) *	2003-07-21	2006-03-30	Pfizer Prod Inc	Compuestos azapoliciclicos arilo fusionados.
US8580842B2 (en)	2003-09-30	2013-11-12	Abbott Gmbh & Co. Kg	Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them
EP1677767B1 (en)	2003-10-14	2011-07-20	XenoPort, Inc.	Crystalline form of gamma-aminobutyric acid analog
CA2549638A1 (en) *	2003-12-23	2005-07-14	Pfizer Products Inc.	Therapeutic combination for cognition enhancement and psychotic disorders
WO2006006071A1 (en) *	2004-07-07	2006-01-19	Pfizer Products Inc.	Resolution of an aryl-fused azapolycyclic compound
CN101128462A (zh) *	2005-02-24	2008-02-20	辉瑞产品有限公司	高纯度取代喹喔啉的制备
RU2403016C2 (ru) *	2006-04-24	2010-11-10	Пфайзер Продактс Инк.	Асимметричные мембраны для устройств доставки лекарственного препарата
MX2009005043A (es) *	2006-11-09	2009-05-25	Pfizer Prod Inc	Polimorfos de intermedios nicotinicos.
US20080167286A1 (en) *	2006-12-12	2008-07-10	Abbott Laboratories	Pharmaceutical compositions and their methods of use
US8486979B2 (en) *	2006-12-12	2013-07-16	Abbvie Inc.	1,2,4 oxadiazole compounds and methods of use thereof
UY30846A1 (es) *	2006-12-30	2008-07-31	Abbott Gmbh & Amp	Derivados de oxindol sustituidos, medicamentos que los comprenden y uso de los mismos
US20090062257A1 (en) *	2007-08-29	2009-03-05	Protia, Llc	Deuterium-enriched varenicline
WO2009034431A2 (en)	2007-09-10	2009-03-19	Pfizer Inc.	Controlled-release dosage forms for varenicline
WO2009065872A2 (en) *	2007-11-20	2009-05-28	Medichem, S.A.	Improved processes for the synthesis of varenicline l-tartrate
US8703774B2 (en) *	2007-12-07	2014-04-22	AbbVie Deutschland GmbH & Co. KG	Carbamate-substituted oxindole derivatives and use thereof for the treatment of vasopressin-dependent diseases
ES2398676T3 (es) *	2007-12-07	2013-03-20	Abbott Gmbh & Co. Kg	Derivados de oxindol sustituidos con amidometilo y su uso para la producción de un medicamento para el tratamiento de enfermedades dependientes de la vasopresina
US8546401B2 (en) *	2007-12-07	2013-10-01	AbbVie Deutschland GmbH & Co. KG	5,6-disubstituted oxindole-derivatives and use thereof for treating vasopressin-dependent diseases
AU2008333123C1 (en) *	2007-12-07	2014-06-19	AbbVie Deutschland GmbH & Co. KG	5-halogen-substituted oxindole derivatives and use thereof for treating vasopressine-dependent diseases
US8383657B2 (en)	2007-12-21	2013-02-26	Abbott Laboratories	Thiazolylidine urea and amide derivatives and methods of use thereof
JP2011516489A (ja) *	2008-03-31	2011-05-26	ユニバーシティ・オブ・サウス・フロリダ	疾患誘発性運動失調症および非運動失調性平衡異常の治療法
CA2709774C (en) *	2008-05-22	2012-10-02	Teva Pharmaceutical Industries Ltd.	Varenicline tosylate, an intermediate in the preparation process of varenicline l-tartrate
WO2009155403A2 (en) *	2008-06-19	2009-12-23	Teva Pharmaceutical Industries Ltd.	Processes for the preparation of varenicline and intermediates thereof
WO2010005643A1 (en) *	2008-07-10	2010-01-14	Teva Pharmaceutical Industries Ltd.	Processes for purifying varenicline l-tartrate salt and preparing crystalline forms of varenicline l-tartrate salt
WO2010023561A1 (en) *	2008-09-01	2010-03-04	Actavis Group Ptc Ehf	Process for preparing varenicline, varenicline intermediates, and pharmaceutically acceptable salts thereof
RU2011137419A (ru)	2009-02-11	2013-03-20	Суновион Фармасьютикалз Инк.	Обратные агонисты и антагонисты гистамина н3 и способы их применения
EP2435080A2 (en)	2009-05-29	2012-04-04	Abbott Laboratories	Pharmaceutical compositions for the treatment of pain
RU2012102052A (ru) *	2009-06-22	2013-11-20	Тева Фармасьютикал Индастриз Лтд.	Твердые формы солей варениклина и способы их получения
KR20180101268A (ko)	2017-03-03	2018-09-12	주식회사 씨티씨바이오	바레니클린 또는 이의 약학적으로 허용가능한 염의 포접 복합체를 포함하는 구강 투여용 제제
CA3161867A1 (en) *	2020-01-03	2021-07-08	Blue Oak Pharmaceuticals, Inc.	Compounds and compositions for treating cns disorders
CN115322105A (zh) *	2021-05-11	2022-11-11	江苏润安制药有限公司	一种合成艾拉莫德关键中间体的方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3471503A (en)	1967-05-05	1969-10-07	Mcneilab Inc	1,2,3,5,6,7-hexahydro-4-phenethyl-2,6-methano-4h-4- benzazonin-12-ols
ME00459B (me) *	1997-12-31	2011-10-10	Pfizer Prod Inc	Aril fuzirana azapoliciklična jedinjenja
EP0955301A3 (en)	1998-04-27	2001-04-18	Pfizer Products Inc.	7-aza-bicyclo[2.2.1]-heptane derivatives, their preparation and use according to their affinity for neuronal nicotinic acetylcholine receptors
YU64400A (sh)	1998-04-29	2003-01-31	Pfizer Products Inc.	Aril fuzirana azapoliciklična jedinjenja
WO2000044755A1 (en) *	1999-01-29	2000-08-03	Abbott Laboratories	Diazabicyclic derivatives as nicotinic acetylcholine receptor ligands
FR2788982B1 (fr) *	1999-02-02	2002-08-02	Synthelabo	Compositions pharmaceutiques contenant de la nicotine et leur application dans le sevrage tabagique
IL137937A0 (en) *	1999-08-27	2001-10-31	Pfizer Prod Inc	A pharmaceutical composition for the prevention and treatment of nicotine addiction in a mammal
CA2441822A1 (en) *	2001-03-19	2002-09-26	Sloan Kettering Institute For Cancer Research	Asymmetric synthesis of (s, s, r)-(-)-actinonin and its analogs and uses therefor
MXPA06000892A (es) *	2003-07-21	2006-03-30	Pfizer Prod Inc	Compuestos azapoliciclicos arilo fusionados.
US8123947B2 (en)	2007-10-22	2012-02-28	Baxter International Inc.	Priming and air removal systems and methods for dialysis

2000
- 2000-02-25 US US09/514,002 patent/US6605610B1/en not_active Expired - Fee Related
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Publication number	Publication date
HUP0204580A2 (hu)	2003-04-28
KR100537976B1 (ko)	2005-12-21
CZ303203B6 (cs)	2012-05-23
NO20024042L (no)	2002-10-17
NZ519973A (en)	2004-04-30
US20030130260A1 (en)	2003-07-10
IL150639A0 (en)	2003-02-12
CR6726A (es)	2003-10-28
ATE453643T1 (de)	2010-01-15
PT1259489E (pt)	2006-08-31
ES2336800T3 (es)	2010-04-16
BG65891B1 (bg)	2010-04-30
DE60120366T2 (de)	2007-07-05
AP1860A (en)	2008-07-02
EP1619192A3 (en)	2006-03-22
HUP0204580A3 (en)	2005-04-28
DK1259489T3 (da)	2006-10-09
MA26875A1 (fr)	2004-12-20
GEP20053454B (en)	2005-02-25
UA74813C2 (en)	2006-02-15
ES2263640T3 (es)	2006-12-16
CN1406227A (zh)	2003-03-26
DK1619192T3 (da)	2010-03-29
EP1619192B1 (en)	2009-12-30
MXPA02008311A (es)	2002-12-09
YU59602A (sh)	2005-06-10
EP1259489B1 (en)	2006-06-07
IS2293B (is)	2007-10-15
BR0108610A (pt)	2002-11-19
CN1263745C (zh)	2006-07-12
RS51123B (sr)	2010-10-31
US20030130261A1 (en)	2003-07-10
DE60120366D1 (de)	2006-07-20
NO323608B1 (no)	2007-06-18
CA2401229C (en)	2007-10-02
DZ3328A1 (xx)	2001-08-30
EA005316B1 (ru)	2004-12-30
SI1259489T1 (sl)	2006-10-31
AU2005234671A1 (en)	2005-12-15
JP2003524002A (ja)	2003-08-12
OA12181A (en)	2006-05-09
SK12042002A3 (sk)	2004-02-03
EE200200475A (et)	2003-12-15
CU23148A3 (es)	2006-06-29
CY1105301T1 (el)	2010-03-03
AU2874801A (en)	2001-09-03
CA2401229A1 (en)	2001-08-30
EA200200716A1 (ru)	2003-02-27
WO2001062736A1 (en)	2001-08-30
NO20024042D0 (no)	2002-08-23
US6605610B1 (en)	2003-08-12
AP2002002604A0 (en)	2002-09-30
PL365163A1 (en)	2004-12-27
KR20030005209A (ko)	2003-01-17
BG106908A (bg)	2003-04-30
AU2005234671B2 (en)	2008-04-17
AU784081B2 (en)	2006-02-02
DE60140965D1 (de)	2010-02-11
HU229482B1 (en)	2014-01-28
IL150639A (en)	2011-10-31
ATE328872T1 (de)	2006-06-15
CZ20022778A3 (cs)	2003-09-17
EP1259489A1 (en)	2002-11-27
US7205300B2 (en)	2007-04-17
EP1619192A2 (en)	2006-01-25
ZA200206768B (en)	2003-09-23
US7144882B2 (en)	2006-12-05
HRP20020700A2 (en)	2004-12-31
IS6459A (is)	2002-07-05

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HK1050894A1 (en)	2003-07-11	Aryl fused azapolycyclic compounds
BG104561A (en)	2001-01-31	Aryl fused azapolycyclic compounds
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WO2004020431A3 (en)	2004-05-13	Novel benzoimidazole derivatives useful as antiproliferative agents
CA2258548A1 (en)	1997-12-31	Phenylamino-substituted tricyclic derivatives for treatment of hyperproliferative diseases
MY140693A (en)	2010-01-15	[1,8]naphthyridin-2-ones and related compounds for the treatment of schizophrenia
SE0104332D0 (sv)	2001-12-19	Therapeutic agents
YU95102A (sh)	2005-11-28	Supstituisani biciklični derivati u lečenju abnormalnog rasta ćelija
MY136270A (en)	2008-09-30	Processes and intermediates for preparing anti-cancer compounds
BG104998A (en)	2001-07-31	Isothiazole derivatives useful as anticancer agents
TW200502221A (en)	2005-01-16	Novel lactams and uses thereof
BG104983A (en)	2001-09-28	Aryl fused azapolycyclic compounds
TW200509933A (en)	2005-03-16	Therapeutic agents
MXPA01007940A (es)	2003-08-20	Derivados de azabicicloalcano y usos terapeuticos de los mismos.
WO2005007630A3 (en)	2005-04-28	Aryl fused azapolycyclic compounds
ATE252546T1 (de)	2003-11-15	3-(3-hydroxyphenyl)-3-amino-propionamidderivate
MXPA99003849A (es)	2003-09-23	Derivados 9a, 11b-deshidro de 9-oxima-3-ceto-6-0-metileritromicina.
SI1704154T1 (sl)	2009-12-31	Novi indeno (2,1a)indeni in izoindol (2,1-a)indoli
MXPA04003688A (es)	2004-07-23	Compuestos azapoliciclicos condensados con arilo.

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