HK1042047B - 用於口服LH-RH類似物的基於α-環糊精的藥物組合物 - Google Patents

用於口服LH-RH類似物的基於α-環糊精的藥物組合物

Info

Publication number: HK1042047B
Authority: HK; Hong Kong
Prior art keywords: cyclodextrin; analogues; alpha; pharmaceutical compositions; oral administration
Prior art date: 1998-09-30

Application number

HK02103697.8A

Other languages

English (en)

Inventor

R‧德蘭索尼

P‧博奈特

J‧帕瑞斯

Original Assignee

塞拉麥克思實驗室公司

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-09-30

Filing date

2002-05-16

Publication date

2005-12-16

2002-05-16 Application filed by 塞拉麥克思實驗室公司 filed Critical 塞拉麥克思實驗室公司

2005-12-16 Publication of HK1042047B publication Critical patent/HK1042047B/zh

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/16—Masculine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
- A61P5/04—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Endocrinology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Reproductive Health (AREA)
Epidemiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Diabetes (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Gynecology & Obstetrics (AREA)
Pregnancy & Childbirth (AREA)
Inorganic Chemistry (AREA)
Zoology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Peptides Or Proteins (AREA)

HK02103697.8A 1998-09-30 2002-05-16 用於口服LH-RH類似物的基於α-環糊精的藥物組合物 HK1042047B (zh)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP98402403A EP0998940A1 (en)	1998-09-30	1998-09-30	Pharmaceutical compositions based on alpha-cyclodextrin for the oral administration of LH-RH analogues
PCT/EP1999/007389 WO2000018423A1 (en)	1998-09-30	1999-09-23	Pharmaceutical compositions based on alpha-cyclodextrin for the oral administration of lh-rh analogues

Publications (1)

Publication Number	Publication Date
HK1042047B true HK1042047B (zh)	2005-12-16

Family

ID=8235503

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HK02103697.8A HK1042047B (zh)	1998-09-30	2002-05-16	用於口服LH-RH類似物的基於α-環糊精的藥物組合物

Country Status (28)

Country	Link
EP (2)	EP0998940A1 (zh)
JP (1)	JP4485060B2 (zh)
KR (1)	KR100652457B1 (zh)
CN (1)	CN1200727C (zh)
AR (1)	AR023056A1 (zh)
AT (1)	ATE218358T1 (zh)
AU (1)	AU756233B2 (zh)
BR (1)	BR9914125A (zh)
CA (1)	CA2344470C (zh)
CZ (1)	CZ302343B6 (zh)
DE (1)	DE69901721T2 (zh)
DK (1)	DK1117420T3 (zh)
EE (1)	EE04872B1 (zh)
ES (1)	ES2178478T3 (zh)
HK (1)	HK1042047B (zh)
HU (1)	HUP0103649A3 (zh)
ID (1)	ID28650A (zh)
IL (2)	IL142112A0 (zh)
MX (1)	MXPA01003340A (zh)
NO (1)	NO330234B1 (zh)
NZ (1)	NZ510446A (zh)
PL (1)	PL200693B1 (zh)
PT (1)	PT1117420E (zh)
RU (1)	RU2214270C2 (zh)
SI (1)	SI1117420T1 (zh)
TR (1)	TR200100887T2 (zh)
WO (1)	WO2000018423A1 (zh)
ZA (1)	ZA200102452B (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10024451A1 (de) *	2000-05-18	2001-11-29	Asta Medica Ag	Pharmazeutische Darreichungsform für Peptide, Verfahren zu deren Herstellung und Verwendung
SE0104462D0 (sv)	2001-12-29	2001-12-29	Carlbiotech Ltd As	Peptide purifcation (Peptidrening)
WO2024210903A1 (en) *	2023-04-07	2024-10-10	Najib Lamharzi	Modified peptide ligands for stable delivery of highly potent payloads to tumors: method of making and using same

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4659696A (en) *	1982-04-30	1987-04-21	Takeda Chemical Industries, Ltd.	Pharmaceutical composition and its nasal or vaginal use
US4659969A (en) *	1984-08-09	1987-04-21	Synektron Corporation	Variable reluctance actuator having position sensing and control
PT88490B (pt) *	1987-09-14	1992-11-30	Novo Nordisk As	Processo para a preparacao de composicoes farmaceuticas para libertacao nao-enterica trans-mucosa contendo monossacaridos ou oligossacaridos
SI9300470A (en) *	1993-09-10	1995-04-30	Lek Tovarna Farmacevtskih	Inclusion complexes of optically active and racemic ibuproxan with cyclodextrin derivates,process for their preparation,pharmaceutical preparations comprising the same and their use
JPH11292787A (ja) *	1995-08-15	1999-10-26	Asahi Chem Ind Co Ltd	生理活性ペプチドを含有する経粘膜投与製剤
WO1997021448A1 (en) *	1995-12-13	1997-06-19	Dullatur Limited	A calcitonin preparation
ES2221019T3 (es) *	1996-10-31	2004-12-16	Takeda Chemical Industries, Ltd.	Preparacion de liberacion mantenida.
EP0842946A1 (en) *	1996-11-14	1998-05-20	Laboratoire Theramex S.A.	Conformationally constrained LH-RH analogues, their uses and pharmaceutical compositions containing them

1998
- 1998-09-30 EP EP98402403A patent/EP0998940A1/en not_active Withdrawn
1999
- 1999-09-23 CZ CZ20011173A patent/CZ302343B6/cs not_active IP Right Cessation
- 1999-09-23 JP JP2000571940A patent/JP4485060B2/ja not_active Expired - Fee Related
- 1999-09-23 IL IL14211299A patent/IL142112A0/xx active IP Right Grant
- 1999-09-23 AU AU61999/99A patent/AU756233B2/en not_active Ceased
- 1999-09-23 HU HU0103649A patent/HUP0103649A3/hu unknown
- 1999-09-23 EP EP99948935A patent/EP1117420B1/en not_active Expired - Lifetime
- 1999-09-23 ZA ZA200102452A patent/ZA200102452B/en unknown
- 1999-09-23 DE DE69901721T patent/DE69901721T2/de not_active Expired - Lifetime
- 1999-09-23 KR KR1020017003614A patent/KR100652457B1/ko not_active IP Right Cessation
- 1999-09-23 SI SI9930098T patent/SI1117420T1/xx unknown
- 1999-09-23 BR BR9914125-6A patent/BR9914125A/pt not_active IP Right Cessation
- 1999-09-23 ID IDW20010683A patent/ID28650A/id unknown
- 1999-09-23 CA CA002344470A patent/CA2344470C/en not_active Expired - Fee Related
- 1999-09-23 NZ NZ510446A patent/NZ510446A/xx not_active IP Right Cessation
- 1999-09-23 CN CNB99812589XA patent/CN1200727C/zh not_active Expired - Fee Related
- 1999-09-23 AT AT99948935T patent/ATE218358T1/de active
- 1999-09-23 PL PL346939A patent/PL200693B1/pl not_active IP Right Cessation
- 1999-09-23 DK DK99948935T patent/DK1117420T3/da active
- 1999-09-23 WO PCT/EP1999/007389 patent/WO2000018423A1/en active IP Right Grant
- 1999-09-23 ES ES99948935T patent/ES2178478T3/es not_active Expired - Lifetime
- 1999-09-23 MX MXPA01003340A patent/MXPA01003340A/es not_active IP Right Cessation
- 1999-09-23 PT PT99948935T patent/PT1117420E/pt unknown
- 1999-09-23 EE EEP200100196A patent/EE04872B1/xx not_active IP Right Cessation
- 1999-09-23 TR TR2001/00887T patent/TR200100887T2/xx unknown
- 1999-09-23 RU RU2001111842/14A patent/RU2214270C2/ru not_active IP Right Cessation
- 1999-09-30 AR ARP990104932A patent/AR023056A1/es not_active Application Discontinuation
2001
- 2001-03-19 IL IL142112A patent/IL142112A/en not_active IP Right Cessation
- 2001-03-28 NO NO20011576A patent/NO330234B1/no not_active IP Right Cessation
2002
- 2002-05-16 HK HK02103697.8A patent/HK1042047B/zh not_active IP Right Cessation

Also Published As

Publication number	Publication date
CA2344470A1 (en)	2000-04-06
DK1117420T3 (da)	2002-09-16
WO2000018423A1 (en)	2000-04-06
EE04872B1 (et)	2007-08-15
NO20011576L (no)	2001-03-28
ZA200102452B (en)	2002-03-26
AU756233B2 (en)	2003-01-09
HUP0103649A2 (hu)	2002-02-28
ATE218358T1 (de)	2002-06-15
IL142112A (en)	2006-10-31
EP1117420B1 (en)	2002-06-05
CZ302343B6 (cs)	2011-03-23
PT1117420E (pt)	2002-10-31
ID28650A (id)	2001-06-21
CA2344470C (en)	2009-01-06
NO20011576D0 (no)	2001-03-28
KR100652457B1 (ko)	2006-11-30
EE200100196A (et)	2002-06-17
MXPA01003340A (es)	2004-04-21
EP1117420A1 (en)	2001-07-25
SI1117420T1 (en)	2002-12-31
BR9914125A (pt)	2001-06-19
HUP0103649A3 (en)	2002-05-28
EP0998940A1 (en)	2000-05-10
TR200100887T2 (tr)	2001-10-22
NO330234B1 (no)	2011-03-07
IL142112A0 (en)	2002-03-10
CZ20011173A3 (cs)	2001-09-12
JP2002525336A (ja)	2002-08-13
RU2214270C2 (ru)	2003-10-20
JP4485060B2 (ja)	2010-06-16
AR023056A1 (es)	2002-09-04
AU6199999A (en)	2000-04-17
KR20010075255A (ko)	2001-08-09
ES2178478T3 (es)	2002-12-16
NZ510446A (en)	2003-01-31
CN1324241A (zh)	2001-11-28
PL346939A1 (en)	2002-03-11
PL200693B1 (pl)	2009-01-30
CN1200727C (zh)	2005-05-11
DE69901721D1 (de)	2002-07-11
DE69901721T2 (de)	2003-01-09

Publication	Publication Date	Title
IL115097A0 (en)	1996-01-19	Pharmaceutical compositions adapted for oral administration
HK1034183A1 (en)	2001-10-19	Galenic formulations of meloxicam for oral administration.
HUP0400887A3 (en)	2012-09-28	Glycopeptide derivatives and pharmaceutical compositions containing the same
HRP980163B1 (en)	2002-10-31	Pharmaceutical composition for the oral administration of an n-piperidinopyrazole -3-carboxamide derivative, its salts and their solvates
HUP0004050A3 (en)	2003-03-28	Itraconazole exhibiting improved solubility, a method of preparing the same and pharmaceutical composition for oral administration comprising the same
HUP0103341A3 (en)	2002-10-28	Azetidine derivatives, preparation and pharmaceutical compositions thereof
IL133397A0 (en)	2001-04-30	Pharmaceutical compositions for oral administration, comprising an active substance and a cyclodextrin
ZA200308221B (en)	2004-09-29	Pharmaceutical compositions for oral and topical administration.
AU2564399A (en)	1999-08-16	Isoflavanoid formulations for oral administration
ZA982112B (en)	1999-09-13	Rapamycin formulations for oral administration.
EP1162884A4 (en)	2002-07-24	LOW-DOSE ORAL COMPOSITIONS OF BUTYRATE COMPOSITIONS
ZA985095B (en)	1999-12-13	Rapamycin formulations for oral administration.
EP0953359A4 (en)	2001-12-19	PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION
AU1732401A (en)	2001-06-18	Medicinal compositions for oral use
HUP0201667A3 (en)	2003-02-28	Oral form of administration
AU6428099A (en)	2000-05-08	Dry deodorizing composition for oral administration
PL346939A1 (en)	2002-03-11	Pharmaceutical compositions based on alpha-cyclodextrin for the oral administration of lh-rh analogues
AU3076600A (en)	2000-08-18	3,7-disubstituted indole derivatives and medicinal compositions containing the same
ZA991539B (en)	1999-08-25	Oral Formulation for hyrophilic drugs.
AU3860797A (en)	1999-02-10	Pharmaceutical formulations for oral administration
HUP0202594A3 (en)	2003-10-28	Streptogramin derivatives, production thereof and pharmaceutical compositions containing the same
AU6473699A (en)	2000-05-22	Aqueous drug formulation for oral application
AU2896897A (en)	1997-12-05	Oral pharmaceutical compositions
AU5249500A (en)	2001-01-09	Medicinal composition for oral administration
EP1133996A4 (en)	2003-04-02	DRUG COMPOSITIONS WITH PERIODIC ADMINISTRATION

Legal Events

Date	Code	Title	Description
2013-04-19	PC	Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)	Effective date: 20120923