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GT201300256A - Procesos para la elaboración de depsipéptidos macrocíclicos y nuevos intermediarios - Google Patents

Procesos para la elaboración de depsipéptidos macrocíclicos y nuevos intermediarios

Info

Publication number
GT201300256A
GT201300256A GT201300256A GT201300256A GT201300256A GT 201300256 A GT201300256 A GT 201300256A GT 201300256 A GT201300256 A GT 201300256A GT 201300256 A GT201300256 A GT 201300256A GT 201300256 A GT201300256 A GT 201300256A
Authority
GT
Guatemala
Prior art keywords
development
processes
depsipeptides
new intermediaries
macrocyclic depsipeptides
Prior art date
Application number
GT201300256A
Other languages
English (en)
Inventor
Acemoglu Murat
Hellstern Heribert
Kollmer Felix
Lopez John
Schreiber Robert
Sprecher Christian
Stettler Hans
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46317455&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GT201300256(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Publication of GT201300256A publication Critical patent/GT201300256A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K11/02—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof cyclic, e.g. valinomycins ; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Cookers (AREA)
  • Cereal-Derived Products (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

LA INVENCIÓN SE REFIERE A UN MÉTODO O PROCESO PARA LA FABRICACIÓN QUÍMICA DE DEPSIPÉPTIDOS DE LA FÓRMULA (I), EN LA QUE LOS SÍMBOLOS TIENEN EL SIGNIFICADO DEFINIDO EN LA DESCRIPCIÓN, A NUEVOS INTERMEDIOS Y SU FABRICACIÓN, ASÍ COMO REALIZACIONES DE LA INVENCIÓN RELACIONADAS.
GT201300256A 2011-04-20 2013-10-18 Procesos para la elaboración de depsipéptidos macrocíclicos y nuevos intermediarios GT201300256A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161477319P 2011-04-20 2011-04-20

Publications (1)

Publication Number Publication Date
GT201300256A true GT201300256A (es) 2015-02-19

Family

ID=46317455

Family Applications (1)

Application Number Title Priority Date Filing Date
GT201300256A GT201300256A (es) 2011-04-20 2013-10-18 Procesos para la elaboración de depsipéptidos macrocíclicos y nuevos intermediarios

Country Status (21)

Country Link
US (2) US8614289B2 (es)
EP (1) EP2699585A1 (es)
JP (2) JP5951006B2 (es)
KR (1) KR101580729B1 (es)
CN (2) CN103476789B (es)
AR (1) AR086168A1 (es)
AU (1) AU2012245980B2 (es)
BR (1) BR112013026660A2 (es)
CA (1) CA2833109A1 (es)
CL (2) CL2013003037A1 (es)
CO (1) CO6801799A2 (es)
EA (2) EA201500734A1 (es)
GT (1) GT201300256A (es)
IL (1) IL228727A0 (es)
MA (1) MA35034B1 (es)
MX (1) MX337526B (es)
PE (1) PE20141206A1 (es)
SG (1) SG193918A1 (es)
TN (1) TN2013000385A1 (es)
TW (1) TW201249863A (es)
WO (1) WO2012143888A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2696570C (en) 2007-08-17 2020-12-29 Novartis Ag Cyclic depsipeptides
AR086168A1 (es) 2011-04-20 2013-11-27 Novartis Ag Procesos para la elaboracion de depsipeptidos macrociclicos e intermediarios
US8680054B2 (en) 2011-04-20 2014-03-25 Novartis Ag Suspension type topical formulations comprising cyclic depsipeptide
US8987413B2 (en) 2012-10-09 2015-03-24 Novartis Ag Aldehyde acetal based processes for the manufacture of macrocyclic depsipeptides and new intermediates
US9067978B2 (en) 2012-10-09 2015-06-30 Novartis Ag Solution phase processes for the manufacture of macrocyclic depsipeptides and new intermediates
CN106029684A (zh) 2014-04-08 2016-10-12 诺华股份有限公司 用于生产大环缩酚酸肽和新中间体的新型缩醛类方法
MX2017014744A (es) * 2015-05-20 2018-05-28 Merial Inc Compuestos depsipeptidicos como anthelminticos.
JP2018530543A (ja) 2015-09-17 2018-10-18 マサチューセッツ インスティテュート オブ テクノロジー 固相ペプチド合成のための方法およびシステム
KR102031186B1 (ko) * 2017-01-11 2019-11-08 주식회사 엘지생활건강 단백질 강도 강화용 조성물
WO2020018888A1 (en) 2018-07-20 2020-01-23 The Board Of Regents Of The University Of Oklahoma Antimicrobial peptides and methods of use

Family Cites Families (26)

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Publication number Priority date Publication date Assignee Title
DE3043252C2 (de) 1980-11-15 1982-12-02 Degussa Ag, 6000 Frankfurt Cyclische Acetale von N-Acylglutaminsäure -γ- semialdehyden, Verfahren zu deren Herstellung und ihre Verwendung
US5595756A (en) 1993-12-22 1997-01-21 Inex Pharmaceuticals Corporation Liposomal compositions for enhanced retention of bioactive agents
DE4421113A1 (de) 1994-06-16 1995-12-21 Biotechnolog Forschung Gmbh Chondramide, Gewinnungsverfahren, Mittel mit Chondramiden und Mischkultur zur Chondramid-Gewinnung
DE19828043A1 (de) 1998-06-24 1999-12-30 Bayer Ag Ektoparasitizide Mittel
JP2000154198A (ja) 1998-11-20 2000-06-06 Nisshin Flour Milling Co Ltd 環状デプシペプチドの固相合成方法及びその中間体
GB0108234D0 (en) * 2001-04-02 2001-05-23 Pharma Mar Sa Process for producing trunkamide A compounds
US20040110228A1 (en) 2002-04-01 2004-06-10 Mcalpine Shelli R. Combinatorial organic synthesis of unique biologically active compounds
SI1631295T1 (sl) 2003-06-06 2010-06-30 Arexis Ab Uporaba kondenziranih heterocikličnih spojin kotSCCE inhibitorjev za zdravljenje kožnih bolezni
GB0322140D0 (en) 2003-09-22 2003-10-22 Pfizer Ltd Combinations
WO2005075667A1 (en) 2004-02-03 2005-08-18 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with kallikrein 7 (klk7)
WO2007101227A2 (en) 2006-02-27 2007-09-07 Arizona Board Of Regents For And On Behalf Of Arizona State University Identification and use of novopeptides for the treatment of cancer
GB0715750D0 (en) 2007-08-13 2007-09-19 Karus Therapeutics Ltd Chemical compounds
EP2183270B1 (en) 2007-08-17 2014-12-17 Novartis AG Use of cyclic depsipeptides to inhibit kallikrein 7
CA2696570C (en) 2007-08-17 2020-12-29 Novartis Ag Cyclic depsipeptides
DE102007052391A1 (de) 2007-10-31 2009-05-07 Henkel Ag & Co. Kgaa Mattwachs
US20110112121A1 (en) 2009-07-06 2011-05-12 Joerg Berghausen Pharmaceutical Compositions and Solid Forms
US20120064013A1 (en) 2010-02-03 2012-03-15 David Marcos Foamable topical composition
KR101004362B1 (ko) 2010-03-19 2010-12-28 가톨릭대학교 산학협력단 자가 면역 질환 예방 및 치료용 ＴＮＦ－α와 ＴＷＥＡＫ 이중 길항제
US20120064136A1 (en) 2010-09-10 2012-03-15 Nanobio Corporation Anti-aging and wrinkle treatment methods using nanoemulsion compositions
CN107714645A (zh) 2011-01-24 2018-02-23 安特里奥公司 纳米颗粒组合物
WO2012103038A2 (en) 2011-01-24 2012-08-02 Anterios, Inc. Nanoparticle compositions, formulations thereof, and uses therefor
US8680054B2 (en) 2011-04-20 2014-03-25 Novartis Ag Suspension type topical formulations comprising cyclic depsipeptide
AR086168A1 (es) 2011-04-20 2013-11-27 Novartis Ag Procesos para la elaboracion de depsipeptidos macrociclicos e intermediarios
US9067978B2 (en) 2012-10-09 2015-06-30 Novartis Ag Solution phase processes for the manufacture of macrocyclic depsipeptides and new intermediates
US8987413B2 (en) 2012-10-09 2015-03-24 Novartis Ag Aldehyde acetal based processes for the manufacture of macrocyclic depsipeptides and new intermediates
CN106029684A (zh) 2014-04-08 2016-10-12 诺华股份有限公司 用于生产大环缩酚酸肽和新中间体的新型缩醛类方法

Also Published As

Publication number Publication date
US20140080995A1 (en) 2014-03-20
JP2014511899A (ja) 2014-05-19
IL228727A0 (en) 2013-12-31
SG193918A1 (en) 2013-11-29
MX2013012188A (es) 2013-11-04
AU2012245980A1 (en) 2013-10-03
KR20130140204A (ko) 2013-12-23
WO2012143888A1 (en) 2012-10-26
MA35034B1 (fr) 2014-04-03
EA201500734A1 (ru) 2015-11-30
EA201391554A1 (ru) 2014-11-28
CN104804072A (zh) 2015-07-29
TN2013000385A1 (en) 2015-01-20
CO6801799A2 (es) 2013-11-29
CL2013003037A1 (es) 2014-10-03
BR112013026660A2 (pt) 2016-09-06
CA2833109A1 (en) 2012-10-26
US8614289B2 (en) 2013-12-24
JP2016164158A (ja) 2016-09-08
KR101580729B1 (ko) 2015-12-28
JP5951006B2 (ja) 2016-07-13
MX337526B (es) 2016-03-09
CN103476789B (zh) 2016-11-09
US20120277406A1 (en) 2012-11-01
US9278997B2 (en) 2016-03-08
PE20141206A1 (es) 2014-09-28
TW201249863A (en) 2012-12-16
CN103476789A (zh) 2013-12-25
EA025546B1 (ru) 2017-01-30
AR086168A1 (es) 2013-11-27
AU2012245980B2 (en) 2015-01-29
EP2699585A1 (en) 2014-02-26
CL2015000688A1 (es) 2015-06-05

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