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GR3036241T3 - METHOD OF TREATMENT OF CHRONIC PROSTATITIS WITH 17-g(b)-N-MONOSUBSTITUTED-CARBAMOYL-4-AZA-5-g(a)-ANDROST-1-EN-3-ONES. - Google Patents

METHOD OF TREATMENT OF CHRONIC PROSTATITIS WITH 17-g(b)-N-MONOSUBSTITUTED-CARBAMOYL-4-AZA-5-g(a)-ANDROST-1-EN-3-ONES.

Info

Publication number
GR3036241T3
GR3036241T3 GR20010401049T GR20010401049T GR3036241T3 GR 3036241 T3 GR3036241 T3 GR 3036241T3 GR 20010401049 T GR20010401049 T GR 20010401049T GR 20010401049 T GR20010401049 T GR 20010401049T GR 3036241 T3 GR3036241 T3 GR 3036241T3
Authority
GR
Greece
Prior art keywords
androst
monosubstituted
aza
treatment
pct
Prior art date
Application number
GR20010401049T
Other languages
English (en)
Inventor
Glenn J Gormley
Elizabeth Stoner
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of GR3036241T3 publication Critical patent/GR3036241T3/el

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
GR20010401049T 1992-12-18 2001-07-19 METHOD OF TREATMENT OF CHRONIC PROSTATITIS WITH 17-g(b)-N-MONOSUBSTITUTED-CARBAMOYL-4-AZA-5-g(a)-ANDROST-1-EN-3-ONES. GR3036241T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US99298592A 1992-12-18 1992-12-18
PCT/US1993/011155 WO1994014452A1 (en) 1992-12-18 1993-11-18 METHOD OF TREATMENT OF CHRONIC PROSTATITIS WITH 17β-N-MONOSUBSTITUTED-CARBAMOYL-4-AZA-5α-ANDROST-1-EN-3-ONES

Publications (1)

Publication Number Publication Date
GR3036241T3 true GR3036241T3 (en) 2001-10-31

Family

ID=25538974

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20010401049T GR3036241T3 (en) 1992-12-18 2001-07-19 METHOD OF TREATMENT OF CHRONIC PROSTATITIS WITH 17-g(b)-N-MONOSUBSTITUTED-CARBAMOYL-4-AZA-5-g(a)-ANDROST-1-EN-3-ONES.

Country Status (17)

Country Link
US (1) US5629318A (el)
EP (1) EP0674521B1 (el)
JP (1) JPH08504813A (el)
AT (1) ATE203162T1 (el)
AU (1) AU691164B2 (el)
CA (1) CA2151239A1 (el)
CZ (1) CZ285379B6 (el)
DE (1) DE69330465T2 (el)
DK (1) DK0674521T3 (el)
ES (1) ES2158887T3 (el)
FI (1) FI953002A0 (el)
GR (1) GR3036241T3 (el)
HU (1) HU220064B (el)
NO (1) NO308829B1 (el)
NZ (1) NZ258435A (el)
PT (1) PT674521E (el)
WO (1) WO1994014452A1 (el)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3993899A (en) * 1998-05-18 1999-12-06 Merck & Co., Inc. Method for treating or preventing chronic nonbacterial prostatitis and prostatodynia
US6645974B2 (en) 2001-07-31 2003-11-11 Merck & Co., Inc. Androgen receptor modulators and methods for use thereof
US7101847B2 (en) * 2002-10-11 2006-09-05 Milkhaus Laboratory, Inc. Method of treating chronic pelvic pain syndrome by administration of chorionic gonadotropin
JP2007505120A (ja) * 2003-09-10 2007-03-08 メルク エンド カムパニー インコーポレーテッド アンドロゲン受容体調節因子としての17−複素環式−4−アザステロイド誘導体。
US7312229B2 (en) * 2003-10-31 2007-12-25 Merck & Co., Inc. 21-Heterocyclic-4-azasteroid derivatives as androgen receptor modulators
US20080268463A1 (en) * 2007-03-07 2008-10-30 Children's Medical Center Corporation Methods for Prognosis and Diagnosis of Chronic Prostatitis/Pelvic Pain Syndrome and Interstitial Cystitis
RU2525182C1 (ru) * 2013-02-28 2014-08-10 Государственное бюджетное образовательное учреждение высшего профессионального образования Первый Московский государственный медицинский университет им. И.М. Сеченова Министерства здравоохранения Российской Федерации (ГБОУ ВПО Первый МГМУ им. И.М. Сеченова Минздрава России) Способ лечения больных хроническим простатитом с парциальным андрогенодефицитом
CN104161739B (zh) * 2014-08-15 2017-09-19 武汉人福药业有限责任公司 非那雄胺胶囊及其制备方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2227876A (en) * 1937-10-16 1941-01-07 Firm Of N V Organon Steroid derivatives with nuclear substituted nitrogen
US3285918A (en) * 1962-04-18 1966-11-15 Norman J Doorenbos 1', 4', 5', 6'-tetrahydropyrimidino[a-4, 3]-4-aza-5-cholestene
US3239417A (en) * 1962-12-07 1966-03-08 Smith Kline French Lab Methods and compositions for inhibiting sterol biosynthesis
US3264301A (en) * 1963-08-22 1966-08-02 Norman J Doorenbos Substituted-4-azasteroids
FR1465544A (fr) * 1965-11-29 1967-01-13 Roussel Uclaf Dérivés stéroïdes aromatiques substitués par un atome d'azote endocyclique et procédé de préparation
US4377584A (en) * 1978-04-13 1983-03-22 Merck & Co., Inc. 4-Aza-17β-substituted-5α-androstan-3-one-reductase inhibitors
US4220775A (en) * 1979-03-15 1980-09-02 Merck & Co., Inc. Preparation of 4-aza-17-substituted-5α-androstan-3-ones useful as 5α-reductase inhibitors
US4760071A (en) * 1984-02-27 1988-07-26 Merck & Co., Inc. 17β-N-monosubstituted carbamoyl-4-aza-5α-androst-1-en-3-ones which are active as testosterone 5α-reductase inhibitors
US5049562A (en) * 1984-02-27 1991-09-17 Merck & Co., Inc. 17β-acyl-4-aza-5α-androst-1-ene-3-ones as 5α-reductase inhibitors
US4859681A (en) * 1984-02-27 1989-08-22 Merck & Co., Inc. 17 α-Acyl-4-aza-5a-androst-1-en-3-ones as 5 alpha-reductase inhibitors
US4845104A (en) * 1986-11-20 1989-07-04 Merck & Co., Inc. Oxidized analogs of 17β-N-monosubstituted-carbamoyl-4-aza-5-α-androstan-3-ones
EP0285383B1 (en) * 1987-04-03 1994-03-16 Merck & Co. Inc. Treatment of prostatic carcinoma with 17beta-n-monosubstituted-carbamoyl-4-aza-5alpha-androst-1-en-3-ones
US4946688A (en) * 1988-07-05 1990-08-07 Fahim Mostafa S Intraprostatic injection of zinc ions for treatment of inflammatory conditions and benign and malignant tumors of the prostate
DK627289D0 (da) * 1989-12-12 1989-12-12 Per C Oden Anvendelse af bicyclononanderivater
US5175155A (en) * 1991-10-07 1992-12-29 Sterling Winthrop Inc. Win 49596-finasteride method of use and compositions
US5710275A (en) * 1992-05-20 1998-01-20 Merck & Co., Inc. 7β-substituted-4-aza-5α-androstan-3-ones as 5α-reductase inhibitors
WO1993023039A1 (en) * 1992-05-20 1993-11-25 Merck & Co., Inc. Substituted 4-aza-5a-androstan-ones as 5a-reductase inhibitors
GB9216284D0 (en) * 1992-07-31 1992-09-16 Erba Carlo Spa Fluorinated 17beta-substituted 4-aza-5alpha-androstane-3-one derivatives
US5693810A (en) * 1992-10-06 1997-12-02 Merck & Co., Inc. 17 β-carboxanilides of 4-aza-5α-androstan-3-ones as 5α-reductase inhibitors

Also Published As

Publication number Publication date
EP0674521A1 (en) 1995-10-04
DE69330465T2 (de) 2002-04-25
NO308829B1 (no) 2000-11-06
NZ258435A (en) 1997-05-26
PT674521E (pt) 2001-10-31
ES2158887T3 (es) 2001-09-16
HU9501777D0 (en) 1995-08-28
DK0674521T3 (da) 2001-09-24
ATE203162T1 (de) 2001-08-15
HU220064B (hu) 2001-10-28
US5629318A (en) 1997-05-13
JPH08504813A (ja) 1996-05-28
CZ157795A3 (en) 1995-11-15
EP0674521A4 (en) 1998-02-04
DE69330465D1 (de) 2001-08-23
AU691164B2 (en) 1998-05-14
AU5610594A (en) 1994-07-19
WO1994014452A1 (en) 1994-07-07
FI953002A (fi) 1995-06-16
FI953002A0 (fi) 1995-06-16
CZ285379B6 (cs) 1999-07-14
EP0674521B1 (en) 2001-07-18
NO952427L (no) 1995-06-16
HUT73231A (en) 1996-07-29
CA2151239A1 (en) 1994-07-07
NO952427D0 (no) 1995-06-16

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