GR3036241T3 - METHOD OF TREATMENT OF CHRONIC PROSTATITIS WITH 17-g(b)-N-MONOSUBSTITUTED-CARBAMOYL-4-AZA-5-g(a)-ANDROST-1-EN-3-ONES. - Google Patents
METHOD OF TREATMENT OF CHRONIC PROSTATITIS WITH 17-g(b)-N-MONOSUBSTITUTED-CARBAMOYL-4-AZA-5-g(a)-ANDROST-1-EN-3-ONES.Info
- Publication number
- GR3036241T3 GR3036241T3 GR20010401049T GR20010401049T GR3036241T3 GR 3036241 T3 GR3036241 T3 GR 3036241T3 GR 20010401049 T GR20010401049 T GR 20010401049T GR 20010401049 T GR20010401049 T GR 20010401049T GR 3036241 T3 GR3036241 T3 GR 3036241T3
- Authority
- GR
- Greece
- Prior art keywords
- androst
- monosubstituted
- aza
- treatment
- pct
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US99298592A | 1992-12-18 | 1992-12-18 | |
PCT/US1993/011155 WO1994014452A1 (en) | 1992-12-18 | 1993-11-18 | METHOD OF TREATMENT OF CHRONIC PROSTATITIS WITH 17β-N-MONOSUBSTITUTED-CARBAMOYL-4-AZA-5α-ANDROST-1-EN-3-ONES |
Publications (1)
Publication Number | Publication Date |
---|---|
GR3036241T3 true GR3036241T3 (en) | 2001-10-31 |
Family
ID=25538974
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR20010401049T GR3036241T3 (en) | 1992-12-18 | 2001-07-19 | METHOD OF TREATMENT OF CHRONIC PROSTATITIS WITH 17-g(b)-N-MONOSUBSTITUTED-CARBAMOYL-4-AZA-5-g(a)-ANDROST-1-EN-3-ONES. |
Country Status (17)
Country | Link |
---|---|
US (1) | US5629318A (el) |
EP (1) | EP0674521B1 (el) |
JP (1) | JPH08504813A (el) |
AT (1) | ATE203162T1 (el) |
AU (1) | AU691164B2 (el) |
CA (1) | CA2151239A1 (el) |
CZ (1) | CZ285379B6 (el) |
DE (1) | DE69330465T2 (el) |
DK (1) | DK0674521T3 (el) |
ES (1) | ES2158887T3 (el) |
FI (1) | FI953002A0 (el) |
GR (1) | GR3036241T3 (el) |
HU (1) | HU220064B (el) |
NO (1) | NO308829B1 (el) |
NZ (1) | NZ258435A (el) |
PT (1) | PT674521E (el) |
WO (1) | WO1994014452A1 (el) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU3993899A (en) * | 1998-05-18 | 1999-12-06 | Merck & Co., Inc. | Method for treating or preventing chronic nonbacterial prostatitis and prostatodynia |
US6645974B2 (en) | 2001-07-31 | 2003-11-11 | Merck & Co., Inc. | Androgen receptor modulators and methods for use thereof |
US7101847B2 (en) * | 2002-10-11 | 2006-09-05 | Milkhaus Laboratory, Inc. | Method of treating chronic pelvic pain syndrome by administration of chorionic gonadotropin |
JP2007505120A (ja) * | 2003-09-10 | 2007-03-08 | メルク エンド カムパニー インコーポレーテッド | アンドロゲン受容体調節因子としての17−複素環式−4−アザステロイド誘導体。 |
US7312229B2 (en) * | 2003-10-31 | 2007-12-25 | Merck & Co., Inc. | 21-Heterocyclic-4-azasteroid derivatives as androgen receptor modulators |
US20080268463A1 (en) * | 2007-03-07 | 2008-10-30 | Children's Medical Center Corporation | Methods for Prognosis and Diagnosis of Chronic Prostatitis/Pelvic Pain Syndrome and Interstitial Cystitis |
RU2525182C1 (ru) * | 2013-02-28 | 2014-08-10 | Государственное бюджетное образовательное учреждение высшего профессионального образования Первый Московский государственный медицинский университет им. И.М. Сеченова Министерства здравоохранения Российской Федерации (ГБОУ ВПО Первый МГМУ им. И.М. Сеченова Минздрава России) | Способ лечения больных хроническим простатитом с парциальным андрогенодефицитом |
CN104161739B (zh) * | 2014-08-15 | 2017-09-19 | 武汉人福药业有限责任公司 | 非那雄胺胶囊及其制备方法 |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2227876A (en) * | 1937-10-16 | 1941-01-07 | Firm Of N V Organon | Steroid derivatives with nuclear substituted nitrogen |
US3285918A (en) * | 1962-04-18 | 1966-11-15 | Norman J Doorenbos | 1', 4', 5', 6'-tetrahydropyrimidino[a-4, 3]-4-aza-5-cholestene |
US3239417A (en) * | 1962-12-07 | 1966-03-08 | Smith Kline French Lab | Methods and compositions for inhibiting sterol biosynthesis |
US3264301A (en) * | 1963-08-22 | 1966-08-02 | Norman J Doorenbos | Substituted-4-azasteroids |
FR1465544A (fr) * | 1965-11-29 | 1967-01-13 | Roussel Uclaf | Dérivés stéroïdes aromatiques substitués par un atome d'azote endocyclique et procédé de préparation |
US4377584A (en) * | 1978-04-13 | 1983-03-22 | Merck & Co., Inc. | 4-Aza-17β-substituted-5α-androstan-3-one-reductase inhibitors |
US4220775A (en) * | 1979-03-15 | 1980-09-02 | Merck & Co., Inc. | Preparation of 4-aza-17-substituted-5α-androstan-3-ones useful as 5α-reductase inhibitors |
US4760071A (en) * | 1984-02-27 | 1988-07-26 | Merck & Co., Inc. | 17β-N-monosubstituted carbamoyl-4-aza-5α-androst-1-en-3-ones which are active as testosterone 5α-reductase inhibitors |
US5049562A (en) * | 1984-02-27 | 1991-09-17 | Merck & Co., Inc. | 17β-acyl-4-aza-5α-androst-1-ene-3-ones as 5α-reductase inhibitors |
US4859681A (en) * | 1984-02-27 | 1989-08-22 | Merck & Co., Inc. | 17 α-Acyl-4-aza-5a-androst-1-en-3-ones as 5 alpha-reductase inhibitors |
US4845104A (en) * | 1986-11-20 | 1989-07-04 | Merck & Co., Inc. | Oxidized analogs of 17β-N-monosubstituted-carbamoyl-4-aza-5-α-androstan-3-ones |
EP0285383B1 (en) * | 1987-04-03 | 1994-03-16 | Merck & Co. Inc. | Treatment of prostatic carcinoma with 17beta-n-monosubstituted-carbamoyl-4-aza-5alpha-androst-1-en-3-ones |
US4946688A (en) * | 1988-07-05 | 1990-08-07 | Fahim Mostafa S | Intraprostatic injection of zinc ions for treatment of inflammatory conditions and benign and malignant tumors of the prostate |
DK627289D0 (da) * | 1989-12-12 | 1989-12-12 | Per C Oden | Anvendelse af bicyclononanderivater |
US5175155A (en) * | 1991-10-07 | 1992-12-29 | Sterling Winthrop Inc. | Win 49596-finasteride method of use and compositions |
US5710275A (en) * | 1992-05-20 | 1998-01-20 | Merck & Co., Inc. | 7β-substituted-4-aza-5α-androstan-3-ones as 5α-reductase inhibitors |
WO1993023039A1 (en) * | 1992-05-20 | 1993-11-25 | Merck & Co., Inc. | Substituted 4-aza-5a-androstan-ones as 5a-reductase inhibitors |
GB9216284D0 (en) * | 1992-07-31 | 1992-09-16 | Erba Carlo Spa | Fluorinated 17beta-substituted 4-aza-5alpha-androstane-3-one derivatives |
US5693810A (en) * | 1992-10-06 | 1997-12-02 | Merck & Co., Inc. | 17 β-carboxanilides of 4-aza-5α-androstan-3-ones as 5α-reductase inhibitors |
-
1993
- 1993-11-18 CZ CZ951577A patent/CZ285379B6/cs not_active IP Right Cessation
- 1993-11-18 WO PCT/US1993/011155 patent/WO1994014452A1/en active IP Right Grant
- 1993-11-18 PT PT94901556T patent/PT674521E/pt unknown
- 1993-11-18 HU HU9501777A patent/HU220064B/hu not_active IP Right Cessation
- 1993-11-18 EP EP94901556A patent/EP0674521B1/en not_active Expired - Lifetime
- 1993-11-18 AU AU56105/94A patent/AU691164B2/en not_active Ceased
- 1993-11-18 NZ NZ258435A patent/NZ258435A/en unknown
- 1993-11-18 AT AT94901556T patent/ATE203162T1/de not_active IP Right Cessation
- 1993-11-18 US US08/448,451 patent/US5629318A/en not_active Expired - Fee Related
- 1993-11-18 ES ES94901556T patent/ES2158887T3/es not_active Expired - Lifetime
- 1993-11-18 DE DE69330465T patent/DE69330465T2/de not_active Expired - Fee Related
- 1993-11-18 JP JP6515148A patent/JPH08504813A/ja active Pending
- 1993-11-18 CA CA002151239A patent/CA2151239A1/en not_active Abandoned
- 1993-11-18 DK DK94901556T patent/DK0674521T3/da active
-
1995
- 1995-06-16 FI FI953002A patent/FI953002A0/fi not_active Application Discontinuation
- 1995-06-16 NO NO952427A patent/NO308829B1/no not_active IP Right Cessation
-
2001
- 2001-07-19 GR GR20010401049T patent/GR3036241T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0674521A1 (en) | 1995-10-04 |
DE69330465T2 (de) | 2002-04-25 |
NO308829B1 (no) | 2000-11-06 |
NZ258435A (en) | 1997-05-26 |
PT674521E (pt) | 2001-10-31 |
ES2158887T3 (es) | 2001-09-16 |
HU9501777D0 (en) | 1995-08-28 |
DK0674521T3 (da) | 2001-09-24 |
ATE203162T1 (de) | 2001-08-15 |
HU220064B (hu) | 2001-10-28 |
US5629318A (en) | 1997-05-13 |
JPH08504813A (ja) | 1996-05-28 |
CZ157795A3 (en) | 1995-11-15 |
EP0674521A4 (en) | 1998-02-04 |
DE69330465D1 (de) | 2001-08-23 |
AU691164B2 (en) | 1998-05-14 |
AU5610594A (en) | 1994-07-19 |
WO1994014452A1 (en) | 1994-07-07 |
FI953002A (fi) | 1995-06-16 |
FI953002A0 (fi) | 1995-06-16 |
CZ285379B6 (cs) | 1999-07-14 |
EP0674521B1 (en) | 2001-07-18 |
NO952427L (no) | 1995-06-16 |
HUT73231A (en) | 1996-07-29 |
CA2151239A1 (en) | 1994-07-07 |
NO952427D0 (no) | 1995-06-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ML | Lapse due to non-payment of fees |