[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

GR3019901T3 - Osteoinductive pharmaceutical formulations - Google Patents

Osteoinductive pharmaceutical formulations

Info

Publication number
GR3019901T3
GR3019901T3 GR960401283T GR960401283T GR3019901T3 GR 3019901 T3 GR3019901 T3 GR 3019901T3 GR 960401283 T GR960401283 T GR 960401283T GR 960401283 T GR960401283 T GR 960401283T GR 3019901 T3 GR3019901 T3 GR 3019901T3
Authority
GR
Greece
Prior art keywords
pharmaceutical formulations
osteoinductive
cartilage
osteoinductive pharmaceutical
formulations
Prior art date
Application number
GR960401283T
Other languages
English (en)
Inventor
Tobin N Gerhart
Elizabeth A Wang
Mary Jo Kriz
Original Assignee
Genetics Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetics Inst filed Critical Genetics Inst
Publication of GR3019901T3 publication Critical patent/GR3019901T3/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
GR960401283T 1990-06-18 1996-05-13 Osteoinductive pharmaceutical formulations GR3019901T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/539,756 US5364839A (en) 1990-06-18 1990-06-18 Osteoinductive pharmaceutical formulations
PCT/US1991/004337 WO1991019510A1 (en) 1990-06-18 1991-06-18 Osteoinductive pharmaceutical formulations

Publications (1)

Publication Number Publication Date
GR3019901T3 true GR3019901T3 (en) 1996-08-31

Family

ID=24152509

Family Applications (1)

Application Number Title Priority Date Filing Date
GR960401283T GR3019901T3 (en) 1990-06-18 1996-05-13 Osteoinductive pharmaceutical formulations

Country Status (10)

Country Link
US (1) US5364839A (el)
EP (1) EP0535091B1 (el)
JP (1) JP3191937B2 (el)
AT (1) ATE136221T1 (el)
CA (1) CA2085750C (el)
DE (1) DE69118535T2 (el)
DK (1) DK0535091T3 (el)
ES (1) ES2088006T3 (el)
GR (1) GR3019901T3 (el)
WO (1) WO1991019510A1 (el)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6150328A (en) 1986-07-01 2000-11-21 Genetics Institute, Inc. BMP products
US6586388B2 (en) 1988-04-08 2003-07-01 Stryker Corporation Method of using recombinant osteogenic protein to repair bone or cartilage defects
US5266683A (en) * 1988-04-08 1993-11-30 Stryker Corporation Osteogenic proteins
US6919308B2 (en) 1988-04-08 2005-07-19 Stryker Corporation Osteogenic devices
US5422340A (en) * 1989-09-01 1995-06-06 Ammann; Arthur J. TGF-βformulation for inducing bone growth
GB2245559A (en) * 1990-06-25 1992-01-08 Farmos Oy Bioceramic system for delivery of a bioactive compound.
US7229959B1 (en) * 1990-11-27 2007-06-12 The American National Red Cross Supplemented fibrin matrix delivery systems
US6197325B1 (en) 1990-11-27 2001-03-06 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
US6054122A (en) 1990-11-27 2000-04-25 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
US6117425A (en) 1990-11-27 2000-09-12 The American National Red Cross Supplemented and unsupplemented tissue sealants, method of their production and use
ATE238417T1 (de) 1991-11-04 2003-05-15 Inst Genetics Llc Rekombinante knochenmorphogenetische protein heterodimere, zusammensetzungen und verfahren zur verwendung
US5661127A (en) * 1995-05-01 1997-08-26 The Regents Of The University Of California Peptide compositions with growth factor-like activity
US6638912B2 (en) 1995-05-01 2003-10-28 The Regents Of The University Of California Peptide compositions mimicking TGF-β activity
US5780436A (en) * 1995-05-01 1998-07-14 The Regents Of The University Of California Peptide compositions with growth factor-like activity
US5902785A (en) * 1995-06-06 1999-05-11 Genetics Institute, Inc. Cartilage induction by bone morphogenetic proteins
US5700774A (en) * 1996-03-26 1997-12-23 Genetics Institute, Inc. Compositions comprising bone morphogenic proteins and truncated parathyroid hormone related peptide, and methods of inducing cartilage by administration of same
US6126682A (en) 1996-08-13 2000-10-03 Oratec Interventions, Inc. Method for treating annular fissures in intervertebral discs
CA2269282A1 (en) 1996-10-23 1998-04-30 Oratec Interventions, Inc. Method and apparatus for treating intervertebral discs
DE69736719T2 (de) 1996-10-23 2007-09-20 Oratec Interventions, Inc., Menlo Park Vorrichtung zur behandlung von zwischenwirbelscheiben
US6593290B1 (en) * 1996-11-01 2003-07-15 Genentech, Inc. Treatment of inner ear hair cells
US7255712B1 (en) 1997-04-15 2007-08-14 Active Implants Corporation Bone growth promoting implant
CN1068793C (zh) * 1997-04-17 2001-07-25 中国人民解放军第四军医大学全军创伤骨科研究所 骨生长刺激素注射剂及其制备方法
IL136230A0 (en) * 1997-11-28 2001-05-20 Roche Diagnostics Gmbh An active hedgehog-protein-mutant, a process for its preparation and its use for pharmaceutical purposes
US6897297B1 (en) * 1997-12-03 2005-05-24 Curis, Inc. Hydrophobically-modified protein compositions and methods
DK0953576T3 (da) * 1998-04-30 2006-03-20 Curis Inc Aktivt hedgehog-proteinkonjugat, fremgangsmåde til fremstilling heraf og anvendelse
DE19841698A1 (de) * 1998-09-11 2000-03-16 Curative Technologies Gmbh Wachstumsfaktor-enthaltende Zusammensetzung zur Heilung von Gewebeschäden
DK1141014T3 (da) 1999-01-06 2005-04-11 Genentech Inc Insulinlignende vækstfaktor (IGF) i mutantvariant
DE19906096A1 (de) 1999-02-13 2000-08-17 Walter Sebald Protein mit einem Heparin-bindenden Epitop
US7189392B1 (en) 1999-10-15 2007-03-13 Genetics Institute, Llc Injectable carrier formulations of hyaluronic acid derivatives for delivery of osteogenic proteins
DK1265630T3 (da) 2000-03-24 2006-10-09 Genentech Inc Anvendelse af insulin til behandling af brusksygdomme
DE10020125A1 (de) * 2000-04-18 2001-10-25 Friedrich Schiller Uni Jena Bu Agens für den postoperativen Einsatz nach Entfernung von Knochentumoren
DE60133271T2 (de) 2000-05-16 2009-04-23 Genentech, Inc., South San Francisco Behandlung von knorpelerkrankungen
ES2304401T3 (es) 2000-10-16 2008-10-16 Genentech, Inc. Metodos de tratamiento que utilizan polipeptidos wisp.
US20020114795A1 (en) 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
TWI267378B (en) 2001-06-08 2006-12-01 Wyeth Corp Calcium phosphate delivery vehicles for osteoinductive proteins
US20080057059A1 (en) * 2001-11-09 2008-03-06 Novo Nordisk Healthcare A/G Pharmaceutical Composition Comprising Factor VII Polypeptides and Protein S Inhibitors
US20030124118A1 (en) * 2001-11-27 2003-07-03 Rasmus Rojkjaer Pharmaceutical composition comprising factor VII polypeptides and protein S inhibitors
WO2003039587A1 (en) * 2001-11-09 2003-05-15 Novo Nordisk Health Care Ag Pharmaceutical composition comprising factor vii polypeptides and protein s inhibitors
ATE457707T1 (de) 2001-12-04 2010-03-15 Active Implants Corp Kissenlagerungsimplantate für lasttragende anwendungen
EP1509161B1 (en) 2002-05-23 2009-05-13 Active Implants Corporation Joint and dental implants
BRPI0413720A (pt) 2003-09-12 2006-10-17 Wyeth Corp bastões e pastas sólidas de fosfato de cálcio injetável para liberação de proteìnas osteogênicas
CN101309698A (zh) * 2005-03-30 2008-11-19 惠氏公司 通过施用bmp来刺激毛发生长的方法
EP1863404A2 (en) * 2005-03-30 2007-12-12 Cartilix, Inc. Coated medical device
US7718616B2 (en) * 2006-12-21 2010-05-18 Zimmer Orthobiologics, Inc. Bone growth particles and osteoinductive composition thereof
US8796206B2 (en) * 2007-11-15 2014-08-05 Amgen Inc. Aqueous formulation of erythropoiesis stimulating protein stabilised by antioxidants for parenteral administration
JP2011519911A (ja) 2008-05-05 2011-07-14 ノヴィミュンヌ エスア 抗ｉｌ１７ａ／ｉｌ−１７ｆ交差反応抗体及びその使用方法
CA2759848C (en) 2009-05-05 2018-12-04 Novimmune S.A. Anti-il-17f antibodies and methods of use thereof
AU2011329054B2 (en) 2010-11-15 2015-05-28 Zimmer Orthobiologics, Inc. Bone void fillers
US11596712B2 (en) 2017-10-19 2023-03-07 Genera Istrazivanja D.O.O. Autologous bone graft substitute composition
EP3697459B1 (en) * 2017-10-19 2022-10-26 GENERA ISTRAZIVANJA d.o.o. Autologous bone graft substitute

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4186448A (en) * 1976-04-16 1980-02-05 Brekke John H Device and method for treating and healing a newly created bone void
SU733665A1 (ru) * 1978-03-30 1980-05-15 Семипалатинский Государственный Медицинский Институт Способ остеосинтеза трубчатых костей
US4430760A (en) * 1981-12-18 1984-02-14 Collagen Corporation Nonstress-bearing implantable bone prosthesis
US4440750A (en) * 1982-02-12 1984-04-03 Collagen Corporation Osteogenic composition and method
US4795804A (en) * 1983-08-16 1989-01-03 The Regents Of The University Of California Bone morphogenetic agents
JPS60100516A (ja) * 1983-11-04 1985-06-04 Takeda Chem Ind Ltd 徐放型マイクロカプセルの製造法
US4563489A (en) * 1984-02-10 1986-01-07 University Of California Biodegradable organic polymer delivery system for bone morphogenetic protein
US4596574A (en) * 1984-05-14 1986-06-24 The Regents Of The University Of California Biodegradable porous ceramic delivery system for bone morphogenetic protein
EP0166263A1 (en) * 1984-05-31 1986-01-02 Green Cross Corporation Filler composition for filling in defect or hollow portion of bone and kit or set for the preparation of the filler composition
US5013649A (en) * 1986-07-01 1991-05-07 Genetics Institute, Inc. DNA sequences encoding osteoinductive products
IL83003A (en) * 1986-07-01 1995-07-31 Genetics Inst Factors that soak bone formation
US5106748A (en) * 1986-07-01 1992-04-21 Genetics Institute, Inc. Dna sequences encoding 5 proteins
ZA874681B (en) * 1986-07-01 1988-04-27 Genetics Inst Novel osteoinductive factors
US4877864A (en) * 1987-03-26 1989-10-31 Genetics Institute, Inc. Osteoinductive factors
US4979959A (en) * 1986-10-17 1990-12-25 Bio-Metric Systems, Inc. Biocompatible coating for solid surfaces
US4902296A (en) * 1986-10-29 1990-02-20 The University Of Virginia Alumni Patents Foundation Use of demineralized bone matrix in the repair of segmental defects
WO1989004646A1 (en) * 1987-11-13 1989-06-01 Jefferies Steven R Bone repair material and delayed drug delivery
IL84911A (en) * 1987-12-22 1993-04-04 Yissum Res Dev Co Processes for the preparation of collagen products, and pharmaceutical compositions containing the same
WO1989009605A1 (en) * 1988-04-06 1989-10-19 Collagen Corporation Bone-inducing protein
US4968590A (en) * 1988-04-08 1990-11-06 Stryker Corporation Osteogenic proteins and polypeptides
EP0408649A4 (en) * 1988-04-08 1991-11-27 Genetics Institute, Inc. Bone and cartilage inductive compositions
US5108436A (en) * 1988-09-29 1992-04-28 Collagen Corporation Implant fixation
DE3939346A1 (de) * 1989-11-29 1991-06-06 Behringwerke Ag Arzneimitel zur subkutanen oder intramuskulaeren applikation enthaltend polypeptide

Also Published As

Publication number Publication date
DE69118535T2 (de) 1996-09-26
ATE136221T1 (de) 1996-04-15
US5364839A (en) 1994-11-15
CA2085750C (en) 2003-02-18
WO1991019510A1 (en) 1991-12-26
JPH05507930A (ja) 1993-11-11
DK0535091T3 (da) 1996-05-06
DE69118535D1 (de) 1996-05-09
EP0535091A1 (en) 1993-04-07
EP0535091B1 (en) 1996-04-03
ES2088006T3 (es) 1996-08-01
JP3191937B2 (ja) 2001-07-23
CA2085750A1 (en) 1991-12-19

Similar Documents

Publication Publication Date Title
GR3019901T3 (en) Osteoinductive pharmaceutical formulations
NO971889D0 (no) Forbindelser og sammensetninger for levering av aktive midler
HK1021824A1 (en) Compositions and methods for treating infections using analogues of indolicidin
DE69835279D1 (de) Zusammensetzungen und verfahren zur behandlung von infektionen unter verwendung von kationischen peptiden allein oder in kombination mit antibiotika
CA2005502A1 (en) Somatotropin analogs
DE69028535D1 (de) Herstellung des vaskulären endothelialen zellwachstumsfaktors
IL99163A0 (en) Inhibitors for serine proteases,their preparation and pharmaceutical compositions containing them
MX9709915A (es) Heterociclos de peptidilo y composiciones que los contienen, utiles en el tratamiento de trastornos relacionados con trombina, y uso de los mismos.
EP0625340A3 (de) Manschette zur Heilbeschleunigung von Knochendefekten.
NZ220894A (en) Peptides of various lengths (37-730 aa) having osteoinductive effects
MX9703643A (es) Metodos para tratamiento de esclerosis multiple usando analogos de peptidos de proteina basica de mielina humana.
AU6020099A (en) Methods for treatment of multiple sclerosis using peptide analogs of human myelin basic protein
ITMI931649A1 (it) Derivati dell'acido 2-ammino-4-fenil-4-osso butirrico
WO1996028470A3 (en) Peptide analogues of human myelin basic protein useful in treating multiple sclerosis
AR244544A1 (es) Composicion desodorante.
NZ239022A (en) Piperidyl ethers and thioethers; preparatory processes and pharmaceutical compositions
IL83775A (en) Amino acid esters and amides of fumaric acid and pharmaceutical compositions containing them for use in the treatment of psoriasis
EP1080724A4 (en) COMPOSITIONS FOR REDUCING MTP ACTIVITY
NO955067D0 (no) FVII/TF peptider
IL95863A0 (en) Anticoagulant peptides and compositions containing them
DK0687270T3 (da) Osteogene vækstoligopeptider og farmaceutiske præparater indeholdende disse
NZ237185A (en) Hiv protease inhibitors containing amino acid units and pharmaceutical compositions thereof
FI942938A0 (fi) Soijaproteiini tai -hydrolysaatit farmaseuttisissa koostumuksissa bioaktiivisten peptidien suojana entsymaattista inaktivoitumista vastaan
AU3494093A (en) S-lipophilic aliphatic carbonyl {n-mercaptoacyl-(amino acid or peptide)} compounds as antihypertensive agents
SI1173194T1 (en) Recombinant sp-a for the treatment or prevention of pulmonary infection and inflammation