GR1007213B - Pharmaceutical levothyroxine sodium formulas - Google Patents
Pharmaceutical levothyroxine sodium formulasInfo
- Publication number
- GR1007213B GR1007213B GR20090100667A GR20090100667A GR1007213B GR 1007213 B GR1007213 B GR 1007213B GR 20090100667 A GR20090100667 A GR 20090100667A GR 20090100667 A GR20090100667 A GR 20090100667A GR 1007213 B GR1007213 B GR 1007213B
- Authority
- GR
- Greece
- Prior art keywords
- formulas
- levothyroxine sodium
- tablets
- pharmaceutical
- pharmaceutical levothyroxine
- Prior art date
Links
- XUIIKFGFIJCVMT-LBPRGKRZSA-N L-thyroxine Chemical compound IC1=CC(C[C@H]([NH3+])C([O-])=O)=CC(I)=C1OC1=CC(I)=C(O)C(I)=C1 XUIIKFGFIJCVMT-LBPRGKRZSA-N 0.000 title abstract 3
- 229960003918 levothyroxine sodium Drugs 0.000 title abstract 3
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 abstract 2
- BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Chemical compound [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 abstract 2
- 239000002274 desiccant Substances 0.000 abstract 1
- 229910052943 magnesium sulfate Inorganic materials 0.000 abstract 1
- 235000019341 magnesium sulphate Nutrition 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229910000027 potassium carbonate Inorganic materials 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention relates to new pharmaceutical levothyroxine sodium formulas in the form of tablets which formulas differentiate to other known compositions in that they contain desiccants (anhydrous magnesium sulphate and anhydrous potassium carbonate). The addition of the above mentioned dehydrators increase the stability of the levothyroxine sodium and prolongs the life time of tablets.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GR20090100667A GR1007213B (en) | 2009-12-07 | 2009-12-07 | Pharmaceutical levothyroxine sodium formulas |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GR20090100667A GR1007213B (en) | 2009-12-07 | 2009-12-07 | Pharmaceutical levothyroxine sodium formulas |
Publications (1)
Publication Number | Publication Date |
---|---|
GR1007213B true GR1007213B (en) | 2011-03-15 |
Family
ID=44913588
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR20090100667A GR1007213B (en) | 2009-12-07 | 2009-12-07 | Pharmaceutical levothyroxine sodium formulas |
Country Status (1)
Country | Link |
---|---|
GR (1) | GR1007213B (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2932963A1 (en) * | 2014-04-16 | 2015-10-21 | Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A. | Stable pharmaceutical dosage forms comprising Levothyroxine sodium |
-
2009
- 2009-12-07 GR GR20090100667A patent/GR1007213B/en active IP Right Grant
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2932963A1 (en) * | 2014-04-16 | 2015-10-21 | Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A. | Stable pharmaceutical dosage forms comprising Levothyroxine sodium |
WO2015158463A1 (en) * | 2014-04-16 | 2015-10-22 | Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A. | Stable pharmaceutical dosage forms comprising levothyroxine sodium |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PG | Patent granted |
Effective date: 20110412 |