GEP201706680BGEAP201313670AGEAP2013013670AGEP201706680BGE P201706680 BGEP201706680 BGE P201706680BGE AP201313670 AGEAP201313670 AGE AP201313670AGE AP2013013670 AGEAP2013013670 AGE AP2013013670AGE P201706680 BGEP201706680 BGE P201706680B
Authority
GE
Georgia
Prior art keywords
catechol
inhibiting compounds
methyltransferase activity
activity inhibiting
compound
Prior art date
Application number
GEAP201313670A
Inventor
Anne Luiro
Belle David Din
Marko Ahlmark
Mika Kauppala
Taina Pajunen
Jarmo Pystynen
Eija Tiainen
Matti Vaismaa
Josef Messinger
Original Assignee
Orion Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion CorpfiledCriticalOrion Corp
Publication of GEP201706680BpublicationCriticalpatent/GEP201706680B/en
Acyclic And Carbocyclic Compounds In Medicinal Compositions
(AREA)
Abstract
Compound of formula (I), which value of substitude R1 is provided in the claims or pharmaceutically acceptable salt or ester thereof, and usage therefor diseases treatment related to inhibitor COMT application, for example, Parkinson's disease. Pharmaceutical composition on basis of said compound.
(4-phenylimidazol-2 -yl) ethylamine derivatives, pharmaceutical compositions containing same and uses thereof in the treatment of diseases for which inhibition of the nav1.8 sodium channel is indicated