GB982572A - Improvements in and relating to quaternary ammonium compounds and the preparation thereof - Google Patents
Improvements in and relating to quaternary ammonium compounds and the preparation thereofInfo
- Publication number
- GB982572A GB982572A GB2060760A GB2060760A GB982572A GB 982572 A GB982572 A GB 982572A GB 2060760 A GB2060760 A GB 2060760A GB 2060760 A GB2060760 A GB 2060760A GB 982572 A GB982572 A GB 982572A
- Authority
- GB
- United Kingdom
- Prior art keywords
- group
- quaternary ammonium
- tertiary amine
- reactive
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention comprises a quaternary ammonium compound containing a cation of the formula <FORM:0982572/C2/1> wherein n is 2 or 3, X and Y are the same or different and each is alkyl or XY is a tetramethylene or pentamethylene group (that is the group NXY is pyrrolidin-1-yl or piperidino), Q2 is a saturated divalent hydrocarbon group containing from 1-3 carbon atoms, R3 is a p-nitrophenyl group which may be substituted in the o- or m-positions by an alkyl or alkoxy group, an L2 is a phenyl group optionally substituted by halogen, and the preparation thereof by reaction of a tertiary amine R4R5R6N with a compound R7Z wherein R4, R5, R6 and R7 are, each as appropriate and not as respective, an R3.O(CH2)n-, an X, a Y, and a -Q2L2 grou and Z is a reactive proton accepting atom or group. For example, a tertiary amine R3O(CH2)nNXY may be quaternized with a reactive phenyl derivative or a tertiary amine XYN.Q2.L2 with a reactive R3O(CH2)nderivative. Pharmaceutical compositions for the treatment of nematode infestations and containing the above quaternary ammonium compounds are administered orally in the forms of tablets, granules, capsules, cachets, suspensions, emulsions or a draft or drench in water or in a syrup.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2060760A GB982572A (en) | 1960-06-10 | 1960-06-10 | Improvements in and relating to quaternary ammonium compounds and the preparation thereof |
| BR12980961A BR6129809D0 (en) | 1960-06-10 | 1961-06-06 | PROCESS FOR THE PREPARATION OF QUATERNARY AMMONIUM COMPOUNDS AS WELL AS AN IMPROVED PHARMACEUTICAL COMPOSITION BASED ON THEM |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2060760A GB982572A (en) | 1960-06-10 | 1960-06-10 | Improvements in and relating to quaternary ammonium compounds and the preparation thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB982572A true GB982572A (en) | 1965-02-10 |
Family
ID=10148732
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2060760A Expired GB982572A (en) | 1960-06-10 | 1960-06-10 | Improvements in and relating to quaternary ammonium compounds and the preparation thereof |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB982572A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0017209A1 (en) * | 1979-04-04 | 1980-10-15 | BASF Aktiengesellschaft | Substituted alkylammonium salts, their preparation and use in plant growth regulation |
| WO1998001417A1 (en) * | 1996-07-08 | 1998-01-15 | Kirin Beer Kabushiki Kaisha | Calcium receptor-active compounds |
-
1960
- 1960-06-10 GB GB2060760A patent/GB982572A/en not_active Expired
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0017209A1 (en) * | 1979-04-04 | 1980-10-15 | BASF Aktiengesellschaft | Substituted alkylammonium salts, their preparation and use in plant growth regulation |
| US4350518A (en) | 1979-04-04 | 1982-09-21 | Basf Aktiengesellschaft | Plant growth regulating substituted alkylammonium salts |
| WO1998001417A1 (en) * | 1996-07-08 | 1998-01-15 | Kirin Beer Kabushiki Kaisha | Calcium receptor-active compounds |
| EP0933354A1 (en) * | 1996-07-08 | 1999-08-04 | Kirin Beer Kabushiki Kaisha | Calcium receptor-active compounds |
| EP0933354A4 (en) * | 1996-07-08 | 2004-09-29 | Kirin Brewery | Calcium receptor-active compounds |
| US6939895B2 (en) | 1996-07-08 | 2005-09-06 | Nps Pharmaceuticals, Inc. | Calcium receptor-active compounds |
| KR100771092B1 (en) | 1996-07-08 | 2007-10-30 | 기린 파마 가부시끼가이샤 | Calcium Receptor-Active Compounds |
| US7816408B2 (en) | 1996-07-08 | 2010-10-19 | Nps Pharmaceuticals, Inc. | Calcium receptor active compounds |
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