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GB2472790A - Dermatological preparations comprising microbes. - Google Patents

Dermatological preparations comprising microbes. Download PDF

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Publication number
GB2472790A
GB2472790A GB0914364A GB0914364A GB2472790A GB 2472790 A GB2472790 A GB 2472790A GB 0914364 A GB0914364 A GB 0914364A GB 0914364 A GB0914364 A GB 0914364A GB 2472790 A GB2472790 A GB 2472790A
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GB
United Kingdom
Prior art keywords
skin
microorganisms
lactobacillus
products described
aspergillus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB0914364A
Other versions
GB0914364D0 (en
Inventor
Laurence Christian Hayes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to GB0914364A priority Critical patent/GB2472790A/en
Publication of GB0914364D0 publication Critical patent/GB0914364D0/en
Publication of GB2472790A publication Critical patent/GB2472790A/en
Withdrawn legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745Bifidobacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747Lactobacilli, e.g. L. acidophilus or L. brevis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/062Ascomycota
    • A61K36/064Saccharomycetales, e.g. baker's yeast
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9728Fungi, e.g. yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mycology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Birds (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Botany (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention relates to products applied to the skin, containing living microorganisms which improve the appearance, health, taste, odour or sensation of the skin.

Description

Background
The ingestion of probiotics is now commonplace in many countries across the world.
Probiotics consist of live microorganisms which when ingested in adequate amounts confer a health benefit on the host.
Studies have shown that human skin is the habitat for a large number of species, genera and phyla of microorganisms.
Skinbiota refers to a range of live microorganisms which when administered to the skin improve the health, appearance, odor, sensation, or taste of the skin.
Description of the Invention:
An object of the present invention is to confer an improvement in the health, appearance, odor, sensation, or taste of the skin through the application of products containing living microorganisms.
The inventor of the present invention has made extensive studies to achieve the above-mentioned objects. As a result, the inventors have discovered that a number of species, and combinations of species, have the ability to improve the health, appearance, odor, sensation, or taste of the skin (or a combination thereof) through a variety of mechanisms.
One example mechanism is the increase in colonization of the skin by a variety of microorganisms which produce anti-oxidant compounds and vitamins. Another example mechanism is the increase in colonization of the skin by microorganisms which produce an odor more pleasant than average body odor. Another example mechanism is the increase in the colonization of the skin by microorganisms which beneficially alter the deoxyrihnucleic acid (dna) and/or rihonucleic acid (ma) of skin cells or reduce the number of microorganisms which have the potential to damage the dna and/or ma of skin cells.
The microorganisms were identified and applied to the skin through a variety of methods including for example in the form of a skin moisturizing cream, a bath additive and a skin wash.
An example product took the form of a liquid containing living microorganisms which when applied as a foot soak resulted in the improvement of foot odor due to an alteration in the population of microorganisms living on the skin of the foot and an alteration in the ph level of the foot skin.
A further example product took the form of a moisturizing cream which contained living microorganisms. The cream was applied to the face and resulted in an alteration in the makeup of microorganisms population of the skin. The living microorganisms included in the cream were selected partly because they were known to produce antioxidant compounds as a result of their metabolic processes.
Antioxidant compounds are known to limit the oxidative damage resulting from Reactive Oxygen Species. Reactive oxygen species damage proteins, nucleic acids, lipids, and other components (biomolecules) in living cells and may contribute to aging. The application of antioxidants to the skin has been demonstrated to improve the appearance of skin and reduce the effects of aging in some instances.
A further example product took the form of a skin cream containing living microorganisms which improved the health of skin suffering from eczema.
A further example product took the form of a liquid gel containing living microorganisms which improved the health of and sensation felt by skin suffering from psoriasis.
A further example product took the form of a bath additive containing living microorganisms which produce a mild lactic acid. The product when applied over time lowered the ph of the skin and improved its appearance.

Claims (12)

  1. Claims 1. Products which contain living microorganisms which are applied to skin and result in the improvement of the health, appearance, odor, taste or sensation of skin.
  2. 2. Products which contain living microorganisms which are applied to the skin and result in a change in the population of the microorganisms living on the skin conferring a benefit to the health, appearance, odor, taste or sensation of skin.
  3. 3. Products described in any of claims 1 to 2 which take the form selected form one of the following: cream, liquid, spray, gel, powder, wash, bath additive, shampoo, or soap.
  4. 4. Products described in any of the claims 1 to 3 which increase the numbers of microorganisms on the skin which beneficially alter the deoxyribonucleic acid (dna) and/or ribonucleic acid (ma) contained within skin cells or reduce the number of microorganisms which have the potential to damage the dna and/or ma of skin cells
  5. 5. Products described in any of claims 1 to 4 above which result in the reduction of skin-inhabiting microorganisms harmful or potentially harmful to the appearance, health, odor, taste or sensation of the skin.
  6. 6. Products described in any of claims 1 to 5 above which contain microorganisms which produce anti-oxidant compounds as a result of their metabolic processes.
  7. 7. Products described in any of claims 1 to 6 above which contain living microorganisms selected from the groups actinomycetes, phototropic bacteria, lactic acid bacteria, yeast and mould fungi wherein: said actinomycetes belong to genus Streptomyces, Streptoverticillium, Nocardia, Micromonospora, or Rhodococcus said phototrophic bacteria belong to genus Rhodopseudomonas, Rhodospirillum, Chromatium or Chlorobium said lactic acid bacteria belong to genus Lactobacillus, Propionibacterium, or Pediococcus; said yeast belong to genus Saccharomyces or Candida; and said mou'd fungi heong to genus Aspergillus or Mucor.
  8. 8. Products described in any of claims 1 to 7 above which contain living microorganisms selected from Streptomyces albus, Streptoverticillium baldaccii, Nocardia asteroides, Micromonospora chalcea or Rhodococcus rhodochrous, Rhodopseudomonas spheroids, Rhodospirillum rubrum, Chlorobium limicola, Lactobacillus bulgaricus, Lactobacillus acidophilus, Lactobacillus casei, Lactobacillus bulgaricus, Lactobacillus johnsonii, Lactobacillus paracasei Escherichia coli, Lactobacillus plantarum, Lactobacillus reuteri, Lactobacillus rhamnosus, Saccharomyces cerevisiae Bifidobacterium species, Streptococcus thermophilus, Propionibacterium freudenreichii, Pediococcus halophilous, Streptococcus lactis, Streptococcus faecalis, Aspergillus japonicus, Aspergillus oryzae, Aspergillus sojae, Aspergillus tamarii, Aspergillus foetidus, Aspergillus niger, Aspergillus oryzae, Mucor hiemalis, Saccharomyces cerevisiae, Saccharomyces lactis and Candida utilis.
  9. 9. Products described in any of claims 1 to 8 above which contain living microorganisms selected because of their ability to produce anti-oxidant compounds or vitamins.
  10. 10. Products described in any of claims 1 to 9 above which contain living microorganisms selected because of their ability to produce anti-oxidant compounds which reduce damage to skin cells caused by Reactive Oxygen Species.
  11. 11. Products described in any of claims 1 to 10 above which contain living microorganisms selected because of their ability to produce either acid or alkaline compounds and therefore alter the ph level of the skin.
  12. 12. Products described in any of claims 1 to 11 above which contain living microorganisms which have been genetically modified.
GB0914364A 2009-08-18 2009-08-18 Dermatological preparations comprising microbes. Withdrawn GB2472790A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB0914364A GB2472790A (en) 2009-08-18 2009-08-18 Dermatological preparations comprising microbes.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB0914364A GB2472790A (en) 2009-08-18 2009-08-18 Dermatological preparations comprising microbes.

Publications (2)

Publication Number Publication Date
GB0914364D0 GB0914364D0 (en) 2009-09-30
GB2472790A true GB2472790A (en) 2011-02-23

Family

ID=41171507

Family Applications (1)

Application Number Title Priority Date Filing Date
GB0914364A Withdrawn GB2472790A (en) 2009-08-18 2009-08-18 Dermatological preparations comprising microbes.

Country Status (1)

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GB (1) GB2472790A (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107412027A (en) * 2017-08-02 2017-12-01 上海交通大学 One primary yeast living cells facial mask and preparation method thereof and application method
CN108486005A (en) * 2018-03-20 2018-09-04 商丘职业技术学院 The preparation method and application of antioxidant of microbial food
US10806769B2 (en) 2016-03-31 2020-10-20 Gojo Industries, Inc. Antimicrobial peptide stimulating cleansing composition
US10874700B2 (en) 2016-03-31 2020-12-29 Gojo Industries, Inc. Sanitizer composition with probiotic/prebiotic active ingredient
US11564879B2 (en) 2016-11-23 2023-01-31 Gojo Industries, Inc. Sanitizer composition with probiotic/prebiotic active ingredient

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003022255A2 (en) * 2001-09-05 2003-03-20 Vsl Pharmaceuticals, Inc. Lactic acid bacteria comprising unmethylated cytosine-guanine dinucleotides for use in therapy
WO2003057380A2 (en) * 2002-01-11 2003-07-17 Whitlock David R Compositions including ammonia oxidizing bacteria and methods of using same
US20040234455A1 (en) * 2001-07-31 2004-11-25 Szalay Aladar A. Light emitting microorganisms and cells for diagnosis and therapy of tumors
WO2005030230A1 (en) * 2003-09-30 2005-04-07 Probiomics Limited Compositions and methods for treatment or prevention of psoriasis and related disorders
US20060002910A1 (en) * 1999-12-22 2006-01-05 Markus Baur Agent for the anti-adhesion of skin pathogenic flora
WO2009000875A2 (en) * 2007-06-27 2008-12-31 Chr. Hansen A/S Lactobacillus helveticus bacterium composition for treatment of atopic dermatitis
US20090123429A1 (en) * 2004-11-03 2009-05-14 Biovite Australia Pty Ltd Arthrospira-based compositions and uses thereof
US20090130073A1 (en) * 2005-09-19 2009-05-21 Basf Se Microorganisms Inhibiting the Formation of Foot Malodor

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060002910A1 (en) * 1999-12-22 2006-01-05 Markus Baur Agent for the anti-adhesion of skin pathogenic flora
US20040234455A1 (en) * 2001-07-31 2004-11-25 Szalay Aladar A. Light emitting microorganisms and cells for diagnosis and therapy of tumors
WO2003022255A2 (en) * 2001-09-05 2003-03-20 Vsl Pharmaceuticals, Inc. Lactic acid bacteria comprising unmethylated cytosine-guanine dinucleotides for use in therapy
WO2003057380A2 (en) * 2002-01-11 2003-07-17 Whitlock David R Compositions including ammonia oxidizing bacteria and methods of using same
WO2005030230A1 (en) * 2003-09-30 2005-04-07 Probiomics Limited Compositions and methods for treatment or prevention of psoriasis and related disorders
US20090123429A1 (en) * 2004-11-03 2009-05-14 Biovite Australia Pty Ltd Arthrospira-based compositions and uses thereof
US20090130073A1 (en) * 2005-09-19 2009-05-21 Basf Se Microorganisms Inhibiting the Formation of Foot Malodor
WO2009000875A2 (en) * 2007-06-27 2008-12-31 Chr. Hansen A/S Lactobacillus helveticus bacterium composition for treatment of atopic dermatitis

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10806769B2 (en) 2016-03-31 2020-10-20 Gojo Industries, Inc. Antimicrobial peptide stimulating cleansing composition
US10874700B2 (en) 2016-03-31 2020-12-29 Gojo Industries, Inc. Sanitizer composition with probiotic/prebiotic active ingredient
US11633451B2 (en) 2016-03-31 2023-04-25 Gojo Industries, Inc. Antimicrobial peptide stimulating cleansing composition
US11998575B2 (en) 2016-03-31 2024-06-04 Gojo Industries, Inc. Sanitizer composition with probiotic/prebiotic active ingredient
US11564879B2 (en) 2016-11-23 2023-01-31 Gojo Industries, Inc. Sanitizer composition with probiotic/prebiotic active ingredient
CN107412027A (en) * 2017-08-02 2017-12-01 上海交通大学 One primary yeast living cells facial mask and preparation method thereof and application method
CN108486005A (en) * 2018-03-20 2018-09-04 商丘职业技术学院 The preparation method and application of antioxidant of microbial food

Also Published As

Publication number Publication date
GB0914364D0 (en) 2009-09-30

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