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GB1514907A - Process for the preparation of substituted phenylguanidines and substituted phenylguanidines when thus prepared - Google Patents

Process for the preparation of substituted phenylguanidines and substituted phenylguanidines when thus prepared

Info

Publication number
GB1514907A
GB1514907A GB41750/77A GB4175077A GB1514907A GB 1514907 A GB1514907 A GB 1514907A GB 41750/77 A GB41750/77 A GB 41750/77A GB 4175077 A GB4175077 A GB 4175077A GB 1514907 A GB1514907 A GB 1514907A
Authority
GB
United Kingdom
Prior art keywords
loweralkyl
hydrogen
substituted
preparation
cycloalkylloweralkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB41750/77A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
William H Rorer Inc
Original Assignee
William H Rorer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by William H Rorer Inc filed Critical William H Rorer Inc
Priority to GB41750/77A priority Critical patent/GB1514907A/en
Publication of GB1514907A publication Critical patent/GB1514907A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

1514907 Substituted phenyl guanidines WILLIAM H RORER Inc 30 May 1975 41750/77 Divided out of 1514198 Addition to 1451480 Heading C2C A process for preparation of compounds of Formula IV (wherein: R 2 , R 3 , R 4 , R 5 and R 6 are the same or different and are each a hydrogen or halogen atom, or a haloloweralkyl, nitro, cyano, loweralkylsulphonyl, loweralkoxy or loweralkyl group, provided at least one of R 2 , R 3 , R 4 , R 6 and R 6 is other than a hydrogen atom; R<SP>a</SP> is a hydrogen atom, or a loweralkyl, intermediate alkyl, loweralkenyl, cyclealkyl, cycloalkylloweralkyl, aralkyl, cycloalkenyl, acyl, aroyl or aryl group; and lower denotes C 1-6 radicals and intermediate denotes C 6-12 radicals and either R<SP>1</SP> and R<SP>11</SP>, which may be the same or different, are each hydrogen, loweralkyl, intermediate alkyl, cycloalkyl, cycloalkylloweralkyl, aralkyl, loweralkenyl, cycloalkenyl, aryl, acyl or aroyl; or R<SP>1</SP> and R<SP>11</SP> together are a loweralkylindenyl or heterolower alkylindenyl) and non-toxic acid addition salts thereof, which process comprises intimately contacting a substituted aniline salt of the formula with a cyanamide N#C-NR<SP>1</SP>R<SP>11</SP> in the presence of phenol cresol oxylenol as solvent at a temperature of 25-150‹ C.
GB41750/77A 1975-05-30 1975-05-30 Process for the preparation of substituted phenylguanidines and substituted phenylguanidines when thus prepared Expired GB1514907A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB41750/77A GB1514907A (en) 1975-05-30 1975-05-30 Process for the preparation of substituted phenylguanidines and substituted phenylguanidines when thus prepared

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB41750/77A GB1514907A (en) 1975-05-30 1975-05-30 Process for the preparation of substituted phenylguanidines and substituted phenylguanidines when thus prepared

Publications (1)

Publication Number Publication Date
GB1514907A true GB1514907A (en) 1978-06-21

Family

ID=10421215

Family Applications (1)

Application Number Title Priority Date Filing Date
GB41750/77A Expired GB1514907A (en) 1975-05-30 1975-05-30 Process for the preparation of substituted phenylguanidines and substituted phenylguanidines when thus prepared

Country Status (1)

Country Link
GB (1) GB1514907A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4713382A (en) * 1985-05-30 1987-12-15 Syntex (U.S.A.) Inc. N-phenyl-4-phenyl-1-piperazinecarboxamidines and related compounds as antiarrhythmic agents
EP0560726A2 (en) 1992-03-11 1993-09-15 Ciba-Geigy Ag Process for the production of guanidine derivatives

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4713382A (en) * 1985-05-30 1987-12-15 Syntex (U.S.A.) Inc. N-phenyl-4-phenyl-1-piperazinecarboxamidines and related compounds as antiarrhythmic agents
EP0560726A2 (en) 1992-03-11 1993-09-15 Ciba-Geigy Ag Process for the production of guanidine derivatives
EP0560726A3 (en) * 1992-03-11 1993-11-18 Ciba Geigy Ag Process for the production of guanidine derivatives
US5276186A (en) * 1992-03-11 1994-01-04 Ciba-Geigy Corporation Process for the production of guanidine derivatives

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]