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GB1423360A - Aziridine derivatives - Google Patents

Aziridine derivatives

Info

Publication number
GB1423360A
GB1423360A GB5913972A GB5913972A GB1423360A GB 1423360 A GB1423360 A GB 1423360A GB 5913972 A GB5913972 A GB 5913972A GB 5913972 A GB5913972 A GB 5913972A GB 1423360 A GB1423360 A GB 1423360A
Authority
GB
United Kingdom
Prior art keywords
alkyl
halo
dec
aryl
anorectic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5913972A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
John Wyeth and Brother Ltd
Original Assignee
John Wyeth and Brother Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by John Wyeth and Brother Ltd filed Critical John Wyeth and Brother Ltd
Priority to GB5913972A priority Critical patent/GB1423360A/en
Publication of GB1423360A publication Critical patent/GB1423360A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/08—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/16—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with acylated ring nitrogen atoms
    • C07D203/18—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with acylated ring nitrogen atoms by carboxylic acids, or by sulfur or nitrogen analogues thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1423360 Anorectic compositions JOHN WYETH & BRO Ltd 10 Dec 1973 [21 Dec 1972] 59139/72 Heading A5B [Also in Division C2] Pharmaceutical compositions having anorectic activity comprise, as active ingredient, an aziridine of the general formula: or a pharmaceutically acceptable acid addition salt thereof, wherein Ar is a phenyl group optionally substituted by one or more hydroxy, halo, C 1-6 alkyl, C 1-6 alkoxy, halo-C 1-6 alkyl, nitro, amino or mono- or di-C 1-6 alkylamnio radicals, R is hydrogen, C 1-6 alkyl, aryl-C 1-6 alkyl or acyl and R' is C 1-6 alkyl, with the proviso that when Ar is phenyl and R' is methyl then R is C 1-6 alkyl or aryl-C 1-6 alkyl, in association with a pharmaceutical carrier, and may be administered in the form of powders, tablets, capsules, solutions, suspensions, emulsions, syrups and elixirs.
GB5913972A 1972-12-21 1972-12-21 Aziridine derivatives Expired GB1423360A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB5913972A GB1423360A (en) 1972-12-21 1972-12-21 Aziridine derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB5913972A GB1423360A (en) 1972-12-21 1972-12-21 Aziridine derivatives

Publications (1)

Publication Number Publication Date
GB1423360A true GB1423360A (en) 1976-02-04

Family

ID=10483133

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5913972A Expired GB1423360A (en) 1972-12-21 1972-12-21 Aziridine derivatives

Country Status (1)

Country Link
GB (1) GB1423360A (en)

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Legal Events

Date Code Title Description
PS Patent sealed
746 Register noted 'licences of right' (sect. 46/1977)
PCNP Patent ceased through non-payment of renewal fee