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GB1311348A - Method for producing a direct compression vehicle for tablets - Google Patents

Method for producing a direct compression vehicle for tablets

Info

Publication number
GB1311348A
GB1311348A GB2039570A GB2039570A GB1311348A GB 1311348 A GB1311348 A GB 1311348A GB 2039570 A GB2039570 A GB 2039570A GB 2039570 A GB2039570 A GB 2039570A GB 1311348 A GB1311348 A GB 1311348A
Authority
GB
United Kingdom
Prior art keywords
particles
sheet
tablets
april
vehicle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2039570A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sucrest Corp
Original Assignee
Sucrest Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sucrest Corp filed Critical Sucrest Corp
Publication of GB1311348A publication Critical patent/GB1311348A/en
Expired legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/22—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by pressing in moulds or between rollers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)

Abstract

1311348 Tableting vehicle SUCREST CORP 28 April 1970 [29 April 1969] 20395/70 Heading A5B A direct compression vehicle for pharmaceutical and like tablets is made by forming a mixture of a plurality of tablet constituents, at least one of which is a "compaction acid", selected from polyethylene glycol (M.W. 2000- 10000), glyceryl monostearate, sorbitol, lactose, mannitol, microcrystalline cellulose, fatty acids, instantized gums, proteins, starch, hydrolysed polysaccharide derivatives, free-flowing, generally spherical agglomerates of sugar particles in a matrix of non-crystalline sugar and free-flowing particulate compositions of inert diluents dispersed in a matrix of hydrophilic, hydratable, high M.W. polymer, compacting the mixture to form a sheet which is compact and coherent and breaking up the sheet to form particles, less than 40% of the sheet being converted to dust (i.e. particles below 325 mesh). Thereafter, the particles are mixed with the remainder of the tablet ingredients, e.g. a lubricant and an active material, and tableted directly by compression. The preferred compaction aids are those materials disclosed in Specification 1310925 and co-pending application 20394/70, which are used in conjunction with sugars.
GB2039570A 1969-04-29 1970-04-28 Method for producing a direct compression vehicle for tablets Expired GB1311348A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82028769A 1969-04-29 1969-04-29

Publications (1)

Publication Number Publication Date
GB1311348A true GB1311348A (en) 1973-03-28

Family

ID=25230391

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2039570A Expired GB1311348A (en) 1969-04-29 1970-04-28 Method for producing a direct compression vehicle for tablets

Country Status (8)

Country Link
US (1) US3639169A (en)
JP (1) JPS5118488B1 (en)
CA (1) CA935761A (en)
DE (1) DE2020619B2 (en)
FR (1) FR2042386B1 (en)
GB (1) GB1311348A (en)
IT (1) IT961361B (en)
NL (1) NL149229B (en)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3900569A (en) * 1971-09-30 1975-08-19 Sucrest Corp Direct compression vehicle
US3987204A (en) * 1972-09-15 1976-10-19 Sucrest Corporation Direct compression vehicle
JPS5418330B2 (en) * 1973-03-16 1979-07-06
US3873694A (en) * 1973-09-27 1975-03-25 Cpc International Inc Direct compression tabletting composition and pharmaceutical tablets produced therefrom
US4115553A (en) * 1973-12-10 1978-09-19 Armour Pharmaceutical Company Antacid tablets
US4209513A (en) * 1974-02-14 1980-06-24 Burroughs Wellcome Co. Tablet formulation
DE2520978C3 (en) * 1975-05-10 1981-02-19 Hoechst Ag, 6000 Frankfurt Dosage unit of a solid, orally administered drug form of water-soluble xanthine derivatives
GB1561301A (en) * 1976-01-02 1980-02-20 Beecham Group Ltd Orally administrable pharmaceutical composition
US4153732A (en) * 1976-01-30 1979-05-08 Indiana University Foundation Anticariogenic comestible
US4134999A (en) * 1977-04-15 1979-01-16 Indiana University Foundation Noncariogenic comestible
US4242330A (en) * 1979-05-30 1980-12-30 The University Of Kentucky Research Foundation Derivative of aspirin
US4241055A (en) * 1979-05-30 1980-12-23 The University Of Kentucky Research Foundation Derivatives of aspirin
US4349542A (en) * 1979-06-08 1982-09-14 National Research Development Corporation Mixture containing active ingredient and dendritic crystalline sugar for tableting
EP0028905B1 (en) * 1979-11-07 1983-04-13 TATE & LYLE PUBLIC LIMITED COMPANY Tablets containing isomaltulose, their use and a method of producing them
US4270956A (en) * 1980-02-15 1981-06-02 Life Savers, Inc. Method for controlling weight of sugar-containing solid shapes and product
US4547358A (en) * 1980-05-06 1985-10-15 Mead Johnson & Company Sustained release tablet containing at least 95 percent theophylline
US5066441A (en) * 1980-12-12 1991-11-19 Rhone-Poulenc Basic Chemicals Co. Process for compacting a calcium phosphate composition
US4465660A (en) * 1981-04-01 1984-08-14 Mead Johnson & Company Sustained release tablet containing at least 95 percent theophylline
US4352821A (en) * 1981-07-21 1982-10-05 Shaklee Corporation Sweet tableting agent
US4495177A (en) * 1983-01-17 1985-01-22 Shaklee Corporation Gel tableting agent
US4659582A (en) * 1983-11-17 1987-04-21 Nabisco Brands, Inc. Compressible soft confection
US4684534A (en) * 1985-02-19 1987-08-04 Dynagram Corporation Of America Quick-liquifying, chewable tablet
US5028633A (en) * 1985-02-21 1991-07-02 Freund Industrial Co., Ltd. Excipient for use in compression molding and process of preparation
US4650669A (en) * 1985-07-30 1987-03-17 Miles Laboratories, Inc. Method to make effervescent calcium tablets and calcium tablets produced thereby
US4810307A (en) * 1987-01-05 1989-03-07 Penford Products Co. Starch hydrolyzate product and method for producing same
US4954178A (en) * 1987-01-05 1990-09-04 Penford Products Co. Starch hydrolyzate product
FR2614219B1 (en) * 1987-04-23 1993-07-09 Materiels Annexes Dialyse PROCESS FOR THE MANUFACTURE OF GRANULES FOR THE PREPARATION OF DIALYSIS SOLUTIONS AND INSTALLATION FOR ITS IMPLEMENTATION.
US4994276A (en) * 1988-09-19 1991-02-19 Edward Mendell Co., Inc. Directly compressible sustained release excipient
US5215752A (en) * 1988-03-17 1993-06-01 Vectorpharma International S.P.A. Pharmaceutical tablets and capsule granulates of scleroglucan and active substance
US5128143A (en) * 1988-09-19 1992-07-07 Edward Mendell Co., Inc. Sustained release excipient and tablet formulation
US5135757A (en) * 1988-09-19 1992-08-04 Edward Mendell Co., Inc. Compressible sustained release solid dosage forms
US5169639A (en) * 1988-09-19 1992-12-08 Edward Mendell Co., Inc. Controlled release verapamil tablets
GB9100009D0 (en) * 1991-01-02 1991-02-20 Cerestar Holding Bv Erythritol compositions
US5254355A (en) * 1992-05-29 1993-10-19 Kraft General Foods, Inc. Process for beverage tablets and products therefrom
US5472711A (en) * 1992-07-30 1995-12-05 Edward Mendell Co., Inc. Agglomerated hydrophilic complexes with multi-phasic release characteristics
US5370878A (en) * 1993-09-30 1994-12-06 Hallmark Pharmaceuticals, Inc. Method for preparing a direct compression granulated acetaminophen composition
US5549757A (en) * 1994-06-10 1996-08-27 Ingredient Technology Corporation Process for recrystallizing sugar and product thereof
IN186245B (en) 1997-09-19 2001-07-14 Ranbaxy Lab Ltd
US6232351B1 (en) * 1998-05-22 2001-05-15 Amway Corporation Co-processed botanical plant composition
US6277407B1 (en) 1998-11-10 2001-08-21 Frederick S. Marius Apparatus and method for tablet fabrication
AU2003234555A1 (en) 2002-05-14 2003-12-02 Fmc Corporation Microcrystalline cewllulose compositions
US20040234660A1 (en) * 2003-05-13 2004-11-25 Bauman Michael N. Process for compression molding a dried aerated confection
US7198653B2 (en) 2003-07-31 2007-04-03 Delavau Llc Calcium carbonate granulation
US7282217B1 (en) 2003-08-29 2007-10-16 Kv Pharmaceutical Company Rapidly disintegrable tablets
EP2455067B1 (en) 2004-05-04 2016-10-12 Innophos, Inc. Directly compressible tricalcium phosphate
US7879382B2 (en) * 2005-09-30 2011-02-01 Fmc Corporation Stabilizers and compositions and products comprising same
US9138414B1 (en) 2006-09-15 2015-09-22 Delavau Llc Calcium supplement having enhanced absorption
US7998505B2 (en) * 2006-10-27 2011-08-16 Fmc Corporation Dry granulation binders, products, and use thereof
CN101167518B (en) * 2007-12-03 2010-06-16 边用福 Anti-melting sugar preparation and preparation method thereof
BR112014007366B1 (en) 2011-10-05 2020-09-15 Dupont Nutrition Usa, Inc PROCESS FOR MANUFACTURING A STABILIZING COMPOSITION UNDERSTANDING TWO-STEP EXTRUSION, STABILIZING COMPOSITION OF MICRO CRYSTALLINE CELLULOSE AND EDIBLE FOOD AND INDUSTRIAL SUSPENSION UNDERSTANDING THE SAME
EP2764045B1 (en) 2011-10-05 2017-03-01 FMC Corporation Stabilizer composition of co-attrited microcrystalline cellulose and carboxymethylcellulose, method for making, and uses
EP2787837B1 (en) 2011-12-09 2017-03-15 FMC Corporation Co-attrited stabilizer composition
US10335374B2 (en) * 2014-12-04 2019-07-02 University System of Georgia, Valdosta State University Tablet composition for anti-tuberculosis antibiotics
JP7264828B2 (en) * 2017-06-07 2023-04-25 ソシエテ・デ・プロデュイ・ネスレ・エス・アー Porous particles for reducing sugar in food
US11058633B2 (en) * 2018-05-17 2021-07-13 Fertin Pharma A/S Disintegrating oral tablet suitable for active pharmaceutical ingredients
WO2022162239A1 (en) 2021-02-01 2022-08-04 Reckitt Benckiser Llc Solid low foaming in dissolution and low ph all-purpose cleaner and disinfectant compositions
GB2603543A (en) 2021-02-01 2022-08-10 Reckitt Benckiser Llc Low foaming in dissolution and low ph all-purpose cleaner and disinfectant tablet

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3305447A (en) * 1963-06-12 1967-02-21 American Sugar Tabletting sugar and method of preparing same
GB1036368A (en) * 1963-10-31 1966-07-20 Nat Dairy Prod Corp Method for the manufacture of lactose-containing tablets

Also Published As

Publication number Publication date
DE2020619A1 (en) 1970-11-05
NL149229B (en) 1976-04-15
FR2042386A1 (en) 1971-02-12
JPS5118488B1 (en) 1976-06-10
FR2042386B1 (en) 1975-04-18
US3639169A (en) 1972-02-01
IT961361B (en) 1973-12-10
CA935761A (en) 1973-10-23
DE2020619B2 (en) 1978-11-16
NL7006185A (en) 1970-11-02

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee