GB1132233A - Medicinal compositions containing sequestering and chelating agents - Google Patents
Medicinal compositions containing sequestering and chelating agentsInfo
- Publication number
- GB1132233A GB1132233A GB2082665A GB2082665A GB1132233A GB 1132233 A GB1132233 A GB 1132233A GB 2082665 A GB2082665 A GB 2082665A GB 2082665 A GB2082665 A GB 2082665A GB 1132233 A GB1132233 A GB 1132233A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acid
- sodium
- group
- chelating agent
- functional group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
- A61K31/78—Polymers containing oxygen of acrylic acid or derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/80—Polymers containing hetero atoms not provided for in groups A61K31/755 - A61K31/795
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/42—Phosphorus; Compounds thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
1,132,233. Pharmaceutical compositions. H. ASHMEAD and F. R. MENCIMER. 17 Aug., 1965, No. 20826/65. Heading A5B. [Also in Division C3] A pharmaceutical composition for the treatment of calcific gall stones, renal calculi, inter alia consists of (a) a phosphate selected from sodium tripolyphosphate (Forms I and II), sodium hexametapyrophosphate, sodium hexametaphosphate, tetrasodium pyrophosphate, tetrapotassium pyrophosphate, S.Q. phosphate i.e. Na 8 P 6 O 11 and sodium acid pyrophosphate together with (b) a chelating agent selected from (I) N,N-di-(2-hydroxyethyl) glycine and the sodium salt thereof, N-(2-hydroxyethyl) ethylene diamine triacetic acid and the trisodium salt thereof, 1,2-diaminocyclohexane tetraacetic acid, nitrilotriacetic acid, 2-hydroxymethyl-5-hydroxy-pyran, and N,N,N'N'- tetrakis (2-hydroxypropyl) ethylene diamine Or (II) ethylene diamine tetraacetic acid, the mono-, di-, tri-, tetrasodium and calcium salts thereof, diethylene triamine pentaacetic acid and pentasodium diethylene triamine pentaacetate and/or (c) an ion-exchange material selected from (III) a resin having a carboxylic acid functional group, sodium alumino-silicate gel, a polystyrene matrix having a nuclear sulphonic acid functional group, a styrene-divinyl benzene copolymer matrix with sulphonic acid functional groups, a hydrocarbon matrix having phosphonic acid groups, a styrene-divinyl benzene copolymer matrix with a quaternary ammonium functional group, and a styrenedivinyl benzene copolymer matrix with a polyalkylamine functional group or (IV) (when the chelating agent, if present, is a chelating agent of group (I)) poly-N-vinyl-5-methyl-2- oxazolidinone and co-polymers of N-vinyl-5- methyl-2-oxazolidinone. When the chelating agent is of group I and/or the ion-exchange material is of group III, the composition may also contain a colloidal carrier e.g. carboxymethylcellulose, sodium carboxymethylcellulose. The invention also includes a composition comprising a phosphate as defined in (a) above together with a chelating agent selected from group I above and/or an ion exchange material selected from group IV above and a colloidal carrier. The compositions may include water as a carrier.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2082665A GB1132233A (en) | 1965-10-22 | 1965-10-22 | Medicinal compositions containing sequestering and chelating agents |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2082665A GB1132233A (en) | 1965-10-22 | 1965-10-22 | Medicinal compositions containing sequestering and chelating agents |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1132233A true GB1132233A (en) | 1968-10-30 |
Family
ID=10152361
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB2082665A Expired GB1132233A (en) | 1965-10-22 | 1965-10-22 | Medicinal compositions containing sequestering and chelating agents |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB1132233A (en) |
Cited By (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4747881A (en) * | 1985-02-05 | 1988-05-31 | Warner-Lambert Company | Ingestible aggregate and delivery system prepared therefrom |
US4774258A (en) * | 1978-05-20 | 1988-09-27 | Martin Rubin | Treatment of urinary calculi |
US4774257A (en) * | 1978-05-20 | 1988-09-27 | Martin Rubin | Treatment of urinary calculi |
US4790991A (en) * | 1985-02-05 | 1988-12-13 | Warner-Lambert Company | Ingestible aggregate and delivery system prepared therefrom |
US4818539A (en) * | 1985-02-05 | 1989-04-04 | Warner-Lambert Company | Ingestible aggregate and delivery system prepared therefrom |
US4843098A (en) * | 1985-02-05 | 1989-06-27 | Warner-Lambert Company | Ingestible aggregate and delivery system prepared therefrom |
US4851392A (en) * | 1985-02-05 | 1989-07-25 | Warner-Lambert Company | Ingestible aggregate and delivery system prepared therefrom |
WO2005060978A2 (en) * | 2003-12-22 | 2005-07-07 | Universitá Degli Studi Di Siena | Polymetaphosphate based formulations for therapy of microcrystalline arthropathies |
US7019085B2 (en) * | 2004-08-30 | 2006-03-28 | Albright Robert L | Phosphate selective resin and related methods |
US9579425B2 (en) | 2012-12-28 | 2017-02-28 | Cook Medical Technologies Llc | Cation exchange ureteral stent |
WO2018165132A1 (en) * | 2017-03-06 | 2018-09-13 | University Of Houston System | Polyphosphates as inhibitors of calcium crystallization |
CN115583710A (en) * | 2022-07-19 | 2023-01-10 | 江苏驰佳环保科技有限公司 | Chelating agent and preparation method thereof |
EP4221859A4 (en) * | 2020-09-30 | 2024-10-23 | Uop Llc | Process for removing ions from bodily fluids |
-
1965
- 1965-10-22 GB GB2082665A patent/GB1132233A/en not_active Expired
Cited By (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4774257A (en) * | 1978-05-20 | 1988-09-27 | Martin Rubin | Treatment of urinary calculi |
US4774258A (en) * | 1978-05-20 | 1988-09-27 | Martin Rubin | Treatment of urinary calculi |
US4851392A (en) * | 1985-02-05 | 1989-07-25 | Warner-Lambert Company | Ingestible aggregate and delivery system prepared therefrom |
US4790991A (en) * | 1985-02-05 | 1988-12-13 | Warner-Lambert Company | Ingestible aggregate and delivery system prepared therefrom |
US4818539A (en) * | 1985-02-05 | 1989-04-04 | Warner-Lambert Company | Ingestible aggregate and delivery system prepared therefrom |
US4843098A (en) * | 1985-02-05 | 1989-06-27 | Warner-Lambert Company | Ingestible aggregate and delivery system prepared therefrom |
US4747881A (en) * | 1985-02-05 | 1988-05-31 | Warner-Lambert Company | Ingestible aggregate and delivery system prepared therefrom |
WO2005060978A2 (en) * | 2003-12-22 | 2005-07-07 | Universitá Degli Studi Di Siena | Polymetaphosphate based formulations for therapy of microcrystalline arthropathies |
WO2005060978A3 (en) * | 2003-12-22 | 2005-08-04 | Univ Siena | Polymetaphosphate based formulations for therapy of microcrystalline arthropathies |
US7019085B2 (en) * | 2004-08-30 | 2006-03-28 | Albright Robert L | Phosphate selective resin and related methods |
US9579425B2 (en) | 2012-12-28 | 2017-02-28 | Cook Medical Technologies Llc | Cation exchange ureteral stent |
WO2018165132A1 (en) * | 2017-03-06 | 2018-09-13 | University Of Houston System | Polyphosphates as inhibitors of calcium crystallization |
EP4221859A4 (en) * | 2020-09-30 | 2024-10-23 | Uop Llc | Process for removing ions from bodily fluids |
CN115583710A (en) * | 2022-07-19 | 2023-01-10 | 江苏驰佳环保科技有限公司 | Chelating agent and preparation method thereof |
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