GB1189720A - Aromatic Sulfamoyl Compounds - Google Patents
Aromatic Sulfamoyl CompoundsInfo
- Publication number
- GB1189720A GB1189720A GB3017469A GB3017469A GB1189720A GB 1189720 A GB1189720 A GB 1189720A GB 3017469 A GB3017469 A GB 3017469A GB 3017469 A GB3017469 A GB 3017469A GB 1189720 A GB1189720 A GB 1189720A
- Authority
- GB
- United Kingdom
- Prior art keywords
- signifies
- aromatic
- benzoic acid
- acid
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- ATCRIUVQKHMXSH-UHFFFAOYSA-N 2,4-dichlorobenzoic acid Chemical compound OC(=O)C1=CC=C(Cl)C=C1Cl ATCRIUVQKHMXSH-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 125000001931 aliphatic group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- MPUNAIYDVXJQBJ-UHFFFAOYSA-N 2,4-dichloro-5-chlorosulfonylbenzoic acid Chemical compound OC(=O)C1=CC(S(Cl)(=O)=O)=C(Cl)C=C1Cl MPUNAIYDVXJQBJ-UHFFFAOYSA-N 0.000 abstract 1
- 239000005711 Benzoic acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229940042795 hydrazides for tuberculosis treatment Drugs 0.000 abstract 1
- 230000003993 interaction Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000010561 standard procedure Methods 0.000 abstract 1
- XTHPWXDJESJLNJ-UHFFFAOYSA-N sulfurochloridic acid Chemical compound OS(Cl)(=O)=O XTHPWXDJESJLNJ-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/42—Halides thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1,189,720. 2,4-Dihalogeno-5-sulphamoylbenzoic acids. CIBA Ltd. 28 Nov., 1967 [5 Dec., 1966; 16 Oct., 1967], No. 30174/69. Divided out of 1,189,719. Heading C2C. Novel compounds I (including salts, esters, acid halides, amides and hydrazides thereof) wherein X signifies halogen, R 3 signifies Cl or Br, R 4 signifies H, acyl, a residue of aliphatic characteristics, an araliphatic or aliphatic residue substituted by a heterocyclic group of aromatic characteristics, and R 5 signifies an aromatic radical or a heterocyclic group of aromatic characteristics, are obtained by reacting an amine, R 4 R 5 .NH, with a 5-chlorosulphonyl-2,4-dihalogeno-benzoic acid (or functional derivative thereof), e.g. 5-chlorosulphonyl- 2,4-dichloro-benzoic acid is prepared by the interaction of 2,4-dichloro-benzoic acid and chlorosulphonic acid. Compounds of the invention may be converted one into the other by standard methods.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US59898066A | 1966-12-05 | 1966-12-05 | |
| US67533067A | 1967-10-16 | 1967-10-16 | |
| DEF0054085 | 1967-11-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1189720A true GB1189720A (en) | 1970-04-29 |
Family
ID=27210549
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3017469A Expired GB1189720A (en) | 1966-12-05 | 1967-11-28 | Aromatic Sulfamoyl Compounds |
| GB5408567D Expired GB1189719A (en) | 1966-12-05 | 1967-11-28 | Aromatic Sulfamoyl Compounds |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5408567D Expired GB1189719A (en) | 1966-12-05 | 1967-11-28 | Aromatic Sulfamoyl Compounds |
Country Status (7)
| Country | Link |
|---|---|
| AT (1) | AT290499B (en) |
| BE (1) | BE707524A (en) |
| CH (1) | CH504416A (en) |
| DE (1) | DE1643279A1 (en) |
| FR (3) | FR1575550A (en) |
| GB (2) | GB1189720A (en) |
| NL (1) | NL6716492A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999010320A1 (en) * | 1997-08-22 | 1999-03-04 | Tularik Inc. | Substituted benzene compounds as antiproliferative and cholesterol lowering agents |
| US6153585A (en) * | 1998-07-20 | 2000-11-28 | Tularik Inc. | Arylsulfonanilide derivatives |
| US6211167B1 (en) | 1998-06-25 | 2001-04-03 | Tularik Inc. | Arylsulfonanilide phosphates |
| US6214880B1 (en) | 1998-09-23 | 2001-04-10 | Tularik Inc. | Arylsulfonanilide ureas |
| US6822001B2 (en) | 2000-11-03 | 2004-11-23 | Tularik Inc. | Combination therapy using pentafluorobenzenesulfonamides and antineoplastic agents |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9824579D0 (en) * | 1998-11-10 | 1999-01-06 | Novartis Ag | Organic compounds |
| DE10112040A1 (en) * | 2001-03-14 | 2002-10-02 | Aventis Pharma Gmbh | Improved process for the preparation of sulfonylcarboxamide derivatives |
| US20060281788A1 (en) | 2005-06-10 | 2006-12-14 | Baumann Christian A | Synergistic modulation of flt3 kinase using a flt3 inhibitor and a farnesyl transferase inhibitor |
| CA2650057C (en) | 2006-04-20 | 2014-07-29 | Janssen Pharmaceutica N.V. | Phenyl- or pyridinyl-amide as inhibitors of c-fms kinase |
| US7414050B2 (en) | 2006-04-20 | 2008-08-19 | Janssen Pharmaceutica, N.V. | Inhibitors of c-fms kinase |
| US8697716B2 (en) | 2006-04-20 | 2014-04-15 | Janssen Pharmaceutica Nv | Method of inhibiting C-KIT kinase |
| JO3240B1 (en) | 2007-10-17 | 2018-03-08 | Janssen Pharmaceutica Nv | Inhibitors of c-fms Kinase |
| AU2013299922B2 (en) | 2012-08-07 | 2018-06-21 | Janssen Pharmaceutica Nv | Process for the preparation of heterocyclic ester derivatives |
| JOP20180012A1 (en) | 2012-08-07 | 2019-01-30 | Janssen Pharmaceutica Nv | Sulfonylation process using nonafluorobutanesulfonyl fluoride |
-
1967
- 1967-11-20 CH CH1621767A patent/CH504416A/en not_active IP Right Cessation
- 1967-11-28 GB GB3017469A patent/GB1189720A/en not_active Expired
- 1967-11-28 GB GB5408567D patent/GB1189719A/en not_active Expired
- 1967-11-30 DE DE19671643279 patent/DE1643279A1/en active Pending
- 1967-12-04 NL NL6716492A patent/NL6716492A/xx unknown
- 1967-12-04 BE BE707524D patent/BE707524A/xx unknown
- 1967-12-04 FR FR1575550D patent/FR1575550A/fr not_active Expired
- 1967-12-04 AT AT1095767A patent/AT290499B/en not_active IP Right Cessation
-
1968
- 1968-02-29 FR FR141758A patent/FR7838M/fr not_active Expired
- 1968-02-29 FR FR141757A patent/FR7837M/fr not_active Expired
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999010320A1 (en) * | 1997-08-22 | 1999-03-04 | Tularik Inc. | Substituted benzene compounds as antiproliferative and cholesterol lowering agents |
| US6211167B1 (en) | 1998-06-25 | 2001-04-03 | Tularik Inc. | Arylsulfonanilide phosphates |
| US6417176B2 (en) | 1998-06-25 | 2002-07-09 | Tularik, Inc. | Arylsulfonanilide phosphates |
| US6153585A (en) * | 1998-07-20 | 2000-11-28 | Tularik Inc. | Arylsulfonanilide derivatives |
| US6630513B1 (en) | 1998-07-20 | 2003-10-07 | Tularix Inc. | Arylsulfonanilide derivates |
| US6214880B1 (en) | 1998-09-23 | 2001-04-10 | Tularik Inc. | Arylsulfonanilide ureas |
| US6583165B2 (en) | 1998-09-23 | 2003-06-24 | Tularik Inc. | Arylsulfonanilide ureas |
| US7060718B2 (en) | 1998-09-23 | 2006-06-13 | Amgen Inc. | Arylsulfonanilide ureas |
| US6822001B2 (en) | 2000-11-03 | 2004-11-23 | Tularik Inc. | Combination therapy using pentafluorobenzenesulfonamides and antineoplastic agents |
Also Published As
| Publication number | Publication date |
|---|---|
| CH504416A (en) | 1971-03-15 |
| FR7837M (en) | 1970-05-25 |
| AT290499B (en) | 1971-06-11 |
| FR1575550A (en) | 1969-07-25 |
| FR7838M (en) | 1970-05-25 |
| DE1643279A1 (en) | 1971-06-09 |
| NL6716492A (en) | 1968-06-06 |
| BE707524A (en) | 1968-06-04 |
| GB1189719A (en) | 1970-04-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |