GB1025735A - Iron preparations for oral administration - Google Patents
Iron preparations for oral administrationInfo
- Publication number
- GB1025735A GB1025735A GB610163A GB610163A GB1025735A GB 1025735 A GB1025735 A GB 1025735A GB 610163 A GB610163 A GB 610163A GB 610163 A GB610163 A GB 610163A GB 1025735 A GB1025735 A GB 1025735A
- Authority
- GB
- United Kingdom
- Prior art keywords
- oral administration
- milk solids
- ferric hydroxide
- hydrogenated dextran
- iron
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940082629 iron antianemic preparations Drugs 0.000 title 1
- NLKNQRATVPKPDG-UHFFFAOYSA-M potassium iodide Chemical compound [K+].[I-] NLKNQRATVPKPDG-UHFFFAOYSA-M 0.000 abstract 3
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 abstract 2
- VYGQUTWHTHXGQB-FFHKNEKCSA-N Retinol Palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C VYGQUTWHTHXGQB-FFHKNEKCSA-N 0.000 abstract 2
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 abstract 2
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 abstract 2
- 235000016709 nutrition Nutrition 0.000 abstract 2
- 239000007787 solid Substances 0.000 abstract 2
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 abstract 1
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 abstract 1
- 244000068988 Glycine max Species 0.000 abstract 1
- 235000010469 Glycine max Nutrition 0.000 abstract 1
- 241000282414 Homo sapiens Species 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 abstract 1
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 abstract 1
- VYGQUTWHTHXGQB-UHFFFAOYSA-N Retinol hexadecanoate Natural products CCCCCCCCCCCCCCCC(=O)OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C VYGQUTWHTHXGQB-UHFFFAOYSA-N 0.000 abstract 1
- WINXNKPZLFISPD-UHFFFAOYSA-M Saccharin sodium Chemical compound [Na+].C1=CC=C2C(=O)[N-]S(=O)(=O)C2=C1 WINXNKPZLFISPD-UHFFFAOYSA-M 0.000 abstract 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 abstract 1
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 abstract 1
- 229920002472 Starch Polymers 0.000 abstract 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 abstract 1
- 229930006000 Sucrose Natural products 0.000 abstract 1
- 235000009470 Theobroma cacao Nutrition 0.000 abstract 1
- 244000299461 Theobroma cacao Species 0.000 abstract 1
- 244000290333 Vanilla fragrans Species 0.000 abstract 1
- 235000009499 Vanilla fragrans Nutrition 0.000 abstract 1
- 235000012036 Vanilla tahitensis Nutrition 0.000 abstract 1
- MECHNRXZTMCUDQ-UHFFFAOYSA-N Vitamin D2 Natural products C1CCC2(C)C(C(C)C=CC(C)C(C)C)CCC2C1=CC=C1CC(O)CCC1=C MECHNRXZTMCUDQ-UHFFFAOYSA-N 0.000 abstract 1
- FAPWYRCQGJNNSJ-UBKPKTQASA-L calcium D-pantothenic acid Chemical compound [Ca+2].OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O.OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O FAPWYRCQGJNNSJ-UBKPKTQASA-L 0.000 abstract 1
- 229940043202 calcium cyclamate Drugs 0.000 abstract 1
- 229960002079 calcium pantothenate Drugs 0.000 abstract 1
- 235000010418 carrageenan Nutrition 0.000 abstract 1
- 239000003240 coconut oil Substances 0.000 abstract 1
- 235000019864 coconut oil Nutrition 0.000 abstract 1
- 229940116318 copper carbonate Drugs 0.000 abstract 1
- 229910000009 copper(II) carbonate Inorganic materials 0.000 abstract 1
- GEZOTWYUIKXWOA-UHFFFAOYSA-L copper;carbonate Chemical compound [Cu+2].[O-]C([O-])=O GEZOTWYUIKXWOA-UHFFFAOYSA-L 0.000 abstract 1
- 239000002285 corn oil Substances 0.000 abstract 1
- 235000005687 corn oil Nutrition 0.000 abstract 1
- 239000011646 cupric carbonate Substances 0.000 abstract 1
- 235000019854 cupric carbonate Nutrition 0.000 abstract 1
- 239000000625 cyclamic acid and its Na and Ca salt Substances 0.000 abstract 1
- ZAKOWWREFLAJOT-UHFFFAOYSA-N d-alpha-Tocopheryl acetate Natural products CC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-UHFFFAOYSA-N 0.000 abstract 1
- 229960002061 ergocalciferol Drugs 0.000 abstract 1
- LFVPBERIVUNMGV-UHFFFAOYSA-N fasudil hydrochloride Chemical compound Cl.C=1C=CC2=CN=CC=C2C=1S(=O)(=O)N1CCCNCC1 LFVPBERIVUNMGV-UHFFFAOYSA-N 0.000 abstract 1
- 235000013861 fat-free Nutrition 0.000 abstract 1
- 229960004887 ferric hydroxide Drugs 0.000 abstract 1
- 235000013312 flour Nutrition 0.000 abstract 1
- 229960000304 folic acid Drugs 0.000 abstract 1
- 235000019152 folic acid Nutrition 0.000 abstract 1
- 239000011724 folic acid Substances 0.000 abstract 1
- 235000012041 food component Nutrition 0.000 abstract 1
- FOYKKGHVWRFIBD-UHFFFAOYSA-N gamma-tocopherol acetate Natural products CC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1 FOYKKGHVWRFIBD-UHFFFAOYSA-N 0.000 abstract 1
- 229910052742 iron Inorganic materials 0.000 abstract 1
- IEECXTSVVFWGSE-UHFFFAOYSA-M iron(3+);oxygen(2-);hydroxide Chemical compound [OH-].[O-2].[Fe+3] IEECXTSVVFWGSE-UHFFFAOYSA-M 0.000 abstract 1
- 239000011702 manganese sulphate Substances 0.000 abstract 1
- 235000007079 manganese sulphate Nutrition 0.000 abstract 1
- SQQMAOCOWKFBNP-UHFFFAOYSA-L manganese(II) sulfate Chemical compound [Mn+2].[O-]S([O-])(=O)=O SQQMAOCOWKFBNP-UHFFFAOYSA-L 0.000 abstract 1
- 235000013336 milk Nutrition 0.000 abstract 1
- 239000008267 milk Substances 0.000 abstract 1
- 210000004080 milk Anatomy 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229960003966 nicotinamide Drugs 0.000 abstract 1
- 235000005152 nicotinamide Nutrition 0.000 abstract 1
- 239000011570 nicotinamide Substances 0.000 abstract 1
- 229960004839 potassium iodide Drugs 0.000 abstract 1
- 235000007715 potassium iodide Nutrition 0.000 abstract 1
- ZUFQODAHGAHPFQ-UHFFFAOYSA-N pyridoxine hydrochloride Chemical compound Cl.CC1=NC=C(CO)C(CO)=C1O ZUFQODAHGAHPFQ-UHFFFAOYSA-N 0.000 abstract 1
- 229960004172 pyridoxine hydrochloride Drugs 0.000 abstract 1
- 235000019171 pyridoxine hydrochloride Nutrition 0.000 abstract 1
- 239000011764 pyridoxine hydrochloride Substances 0.000 abstract 1
- 229940108325 retinyl palmitate Drugs 0.000 abstract 1
- 235000019172 retinyl palmitate Nutrition 0.000 abstract 1
- 239000011769 retinyl palmitate Substances 0.000 abstract 1
- 229960002477 riboflavin Drugs 0.000 abstract 1
- 235000019192 riboflavin Nutrition 0.000 abstract 1
- 239000002151 riboflavin Substances 0.000 abstract 1
- 229960005055 sodium ascorbate Drugs 0.000 abstract 1
- 235000010378 sodium ascorbate Nutrition 0.000 abstract 1
- PPASLZSBLFJQEF-RKJRWTFHSA-M sodium ascorbate Substances [Na+].OC[C@@H](O)[C@H]1OC(=O)C(O)=C1[O-] PPASLZSBLFJQEF-RKJRWTFHSA-M 0.000 abstract 1
- 239000008107 starch Substances 0.000 abstract 1
- 235000019698 starch Nutrition 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000005720 sucrose Substances 0.000 abstract 1
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 abstract 1
- 229960000344 thiamine hydrochloride Drugs 0.000 abstract 1
- 235000019190 thiamine hydrochloride Nutrition 0.000 abstract 1
- 239000011747 thiamine hydrochloride Substances 0.000 abstract 1
- MECHNRXZTMCUDQ-RKHKHRCZSA-N vitamin D2 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)/C=C/[C@H](C)C(C)C)=C\C=C1\C[C@@H](O)CCC1=C MECHNRXZTMCUDQ-RKHKHRCZSA-N 0.000 abstract 1
- 235000001892 vitamin D2 Nutrition 0.000 abstract 1
- 239000011653 vitamin D2 Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
- 235000008939 whole milk Nutrition 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/295—Iron group metal compounds
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicinal Preparation (AREA)
Abstract
Compositions suitable for the oral administration of iron to human beings and animals comprise a substantially non-ionic complex of ferric hydroxide and hydrogenated dextran having an intrinsic viscosity at 25 DEG C. of between 0.025 and 0.5, which is stable in contact with water, and dietary components having nutritional value. (The ferric hydroxide-hydrogenated dextran complexes are described in Specifications 937,235 and 1,019,513.) Nutritional substances specified are non-fat milk solids, soya flour, whole milk solids, sucrose, starch, corn oil, coconut oil, yeast, vanilla, cocoa, calcium cyclamate, saccharin, sodium ascorbate, chondrus extract, niacinamide, tocopheryl acetate, manganese sulphate, calcium pantothenate, cupric carbonate, pyridoxine hydrochloride, thiamine hydrochloride, riboflavin, folic acid, potassium iodide, vitamin A palmitate and calciferol.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17313162A | 1962-02-14 | 1962-02-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1025735A true GB1025735A (en) | 1966-04-14 |
Family
ID=22630668
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB610163A Expired GB1025735A (en) | 1962-02-14 | 1963-02-14 | Iron preparations for oral administration |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB1025735A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2085700A1 (en) * | 1970-03-13 | 1971-12-31 | Fisons Ltd | |
| GB2196847A (en) * | 1986-05-27 | 1988-05-11 | Ciba Geigy Ag | Multi mineral dietary supplement with controlled release bioavailable iron |
| US7772334B2 (en) * | 2006-10-26 | 2010-08-10 | Basf Coatings Gmbh | Crosslinker of reactive functional groups and nonionic metal coordinating structure-containing alkyl or aromatic compound |
-
1963
- 1963-02-14 GB GB610163A patent/GB1025735A/en not_active Expired
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2085700A1 (en) * | 1970-03-13 | 1971-12-31 | Fisons Ltd | |
| GB2196847A (en) * | 1986-05-27 | 1988-05-11 | Ciba Geigy Ag | Multi mineral dietary supplement with controlled release bioavailable iron |
| GB2196847B (en) * | 1986-05-27 | 1990-03-14 | Ciba Geigy Ag | Multi vitamin and mineral dietary supplement with controlled release bioavailable iron |
| US7772334B2 (en) * | 2006-10-26 | 2010-08-10 | Basf Coatings Gmbh | Crosslinker of reactive functional groups and nonionic metal coordinating structure-containing alkyl or aromatic compound |
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