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GB1092737A - 2-methoxy-4-[n-glutarylsulfanilamido]quinazoline and process for preparing the same - Google Patents

2-methoxy-4-[n-glutarylsulfanilamido]quinazoline and process for preparing the same

Info

Publication number
GB1092737A
GB1092737A GB1759266A GB1759266A GB1092737A GB 1092737 A GB1092737 A GB 1092737A GB 1759266 A GB1759266 A GB 1759266A GB 1759266 A GB1759266 A GB 1759266A GB 1092737 A GB1092737 A GB 1092737A
Authority
GB
United Kingdom
Prior art keywords
methoxy
quinazoline
glutarylsulfanilamido
preparing
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1759266A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mead Johnson and Co LLC
Original Assignee
Mead Johnson and Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mead Johnson and Co LLC filed Critical Mead Johnson and Co LLC
Publication of GB1092737A publication Critical patent/GB1092737A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The novel compound 2-methoxy-4-(N4-glutarylsulphanilamido)quinazoline, and the pharmaceutically acceptable metal salts thereof, are prepared by reacting 2-methoxy-4-sulphanilamidoquinazoline with glutaric anhydride, and, if desired, converting the product into a metal salt.ALSO:Pharmaceutical compositions having antibacterial activity, which may be administered orally or parenterally, contain as active ingredient 2-methoxy-4-(N4-glutarylsulphanilamido)-quinazoline, or a pharmaceutically acceptable metal salt thereof, if desired, in association with other drugs such as antibiotics, including the macrolyde antibiotics, the penicillins and the tetracyclines, or with anti-inflammatory or antipyretic drugs such as the salicylates.
GB1759266A 1965-06-02 1966-04-21 2-methoxy-4-[n-glutarylsulfanilamido]quinazoline and process for preparing the same Expired GB1092737A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US46082665A 1965-06-02 1965-06-02

Publications (1)

Publication Number Publication Date
GB1092737A true GB1092737A (en) 1967-11-29

Family

ID=23830221

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1759266A Expired GB1092737A (en) 1965-06-02 1966-04-21 2-methoxy-4-[n-glutarylsulfanilamido]quinazoline and process for preparing the same

Country Status (11)

Country Link
BE (1) BE681054A (en)
BR (1) BR6679429D0 (en)
CH (1) CH477451A (en)
DE (1) DE1595997A1 (en)
DK (1) DK120545B (en)
ES (1) ES326754A1 (en)
FR (1) FR1583159A (en)
GB (1) GB1092737A (en)
IL (1) IL25640A (en)
NL (1) NL6606492A (en)
SE (1) SE325888B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002087587A2 (en) * 2001-05-02 2002-11-07 Celltech R & D Limited 4-aminosulfonylquinazolines and -quinolines as tyrosine kinase inhibitors
US7012076B2 (en) * 2000-03-29 2006-03-14 Celltech R&D Limited Bicyclic amine derivatives as inhibitors of class 1 receptor tyrosine kinases

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7012076B2 (en) * 2000-03-29 2006-03-14 Celltech R&D Limited Bicyclic amine derivatives as inhibitors of class 1 receptor tyrosine kinases
WO2002087587A2 (en) * 2001-05-02 2002-11-07 Celltech R & D Limited 4-aminosulfonylquinazolines and -quinolines as tyrosine kinase inhibitors
WO2002087587A3 (en) * 2001-05-02 2003-01-09 Celltech R&D Ltd 4-aminosulfonylquinazolines and -quinolines as tyrosine kinase inhibitors

Also Published As

Publication number Publication date
FR1583159A (en) 1969-10-24
SE325888B (en) 1970-07-13
BR6679429D0 (en) 1973-10-23
IL25640A (en) 1970-01-29
BE681054A (en) 1966-11-14
CH477451A (en) 1969-08-31
NL6606492A (en) 1966-12-05
DK120545B (en) 1971-06-14
ES326754A1 (en) 1967-03-16
DE1595997A1 (en) 1970-03-19

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