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GB1076984A - Improvements in or relating to local anaesthetics containing orn-vasopressin - Google Patents

Improvements in or relating to local anaesthetics containing orn-vasopressin

Info

Publication number
GB1076984A
GB1076984A GB31351/64A GB3135164A GB1076984A GB 1076984 A GB1076984 A GB 1076984A GB 31351/64 A GB31351/64 A GB 31351/64A GB 3135164 A GB3135164 A GB 3135164A GB 1076984 A GB1076984 A GB 1076984A
Authority
GB
United Kingdom
Prior art keywords
vasopressin
relating
local anaesthetics
diethylamino
orn
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB31351/64A
Inventor
Roger Boissonnas
Botond Berde
Walter Schalch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH436163A external-priority patent/CH421129A/en
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of GB1076984A publication Critical patent/GB1076984A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/16—Oxytocins; Vasopressins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/095—Oxytocins; Vasopressins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Emergency Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Local anaesthetic compositions comprise orn8-vasopressin together with a local anaesthetic selected from 2-diethylamino-21,61-acetoxylidide, p-aminobenzoyl diethylaminoethanol, p-aminobenzoic acid-b -diethylamino-b -isobutylethyl ester, (\sB)-N-(2-propylamino propionyl)-2-toluidine and acid addition salts thereof. The compositions may be used for block, infiltration, or surface anesthesia.
GB31351/64A 1963-04-05 1964-08-04 Improvements in or relating to local anaesthetics containing orn-vasopressin Expired GB1076984A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH436163A CH421129A (en) 1963-04-05 1963-04-05 Process for the production of a previously unknown polypeptide
CH972463 1963-08-06

Publications (1)

Publication Number Publication Date
GB1076984A true GB1076984A (en) 1967-07-26

Family

ID=25695275

Family Applications (1)

Application Number Title Priority Date Filing Date
GB31351/64A Expired GB1076984A (en) 1963-04-05 1964-08-04 Improvements in or relating to local anaesthetics containing orn-vasopressin

Country Status (2)

Country Link
BE (1) BE651400A (en)
GB (1) GB1076984A (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4377573A (en) * 1978-01-06 1983-03-22 Leveen Harry H Method of control of gastrointestinal bleeding
WO2007144768A3 (en) * 2006-02-13 2008-05-15 Ferring Bv Use of peptidic vasopressin receptor agonists
US8778881B2 (en) 2004-08-11 2014-07-15 Ferring B.V. Peptidic vasopressin receptor agonists
US8883965B2 (en) 2006-02-10 2014-11-11 Ferring B.V. Compounds
US9050286B2 (en) 2007-08-14 2015-06-09 Ferring B.V. Use of peptidic vasopression receptor agonists

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4377573A (en) * 1978-01-06 1983-03-22 Leveen Harry H Method of control of gastrointestinal bleeding
US8778881B2 (en) 2004-08-11 2014-07-15 Ferring B.V. Peptidic vasopressin receptor agonists
US8883965B2 (en) 2006-02-10 2014-11-11 Ferring B.V. Compounds
WO2007144768A3 (en) * 2006-02-13 2008-05-15 Ferring Bv Use of peptidic vasopressin receptor agonists
US8222202B2 (en) 2006-02-13 2012-07-17 Ferring B.V. Use of peptidic vasopressin receptor agonists
US9050286B2 (en) 2007-08-14 2015-06-09 Ferring B.V. Use of peptidic vasopression receptor agonists

Also Published As

Publication number Publication date
BE651400A (en) 1965-02-04

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