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FR7475M - - Google Patents

Info

Publication number
FR7475M
FR7475M FR148055A FR148055A FR7475M FR 7475 M FR7475 M FR 7475M FR 148055 A FR148055 A FR 148055A FR 148055 A FR148055 A FR 148055A FR 7475 M FR7475 M FR 7475M
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR148055A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP6951067A external-priority patent/JPS4614736B1/ja
Application filed filed Critical
Application granted granted Critical
Publication of FR7475M publication Critical patent/FR7475M/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A47—FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
    • A47L—DOMESTIC WASHING OR CLEANING; SUCTION CLEANERS IN GENERAL
    • A47L13/00—Implements for cleaning floors, carpets, furniture, walls, or wall coverings
    • A47L13/02—Scraping
    • A47L13/04—Scraping with steel wool

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR148055A 1967-04-15 1968-04-12 Expired FR7475M (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2397167 1967-04-15
JP6842967 1967-10-24
JP6951067A JPS4614736B1 (fr) 1967-10-28 1967-10-28

Publications (1)

Publication Number Publication Date
FR7475M true FR7475M (fr) 1969-12-01

Family

ID=27284465

Family Applications (1)

Application Number Title Priority Date Filing Date
FR148055A Expired FR7475M (fr) 1967-04-15 1968-04-12

Country Status (10)

Country Link
US (1) US3516997A (fr)
AT (1) AT292193B (fr)
CA (1) CA928292A (fr)
CH (2) CH527215A (fr)
DE (1) DE1795838B2 (fr)
ES (3) ES352625A1 (fr)
FR (1) FR7475M (fr)
GB (1) GB1206305A (fr)
NL (1) NL164560C (fr)
SE (1) SE369908B (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2411839A1 (fr) * 1977-11-14 1979-07-13 Fujisawa Pharmaceutical Co Derives de l'acide cephalosporanique, procedes pour leur preparation et composition pharmaceutique les contenant
EP0070803A2 (fr) * 1981-07-16 1983-01-26 Ciba-Geigy Ag Dérivés d'aminotriazolylcéphalosporine antibiotiques et leur préparation
EP0076452A2 (fr) * 1981-09-30 1983-04-13 Ciba-Geigy Ag Dérivés de céphalosporine, procédé pour leur préparation et les compositions pharmaceutiques les contenant

Families Citing this family (91)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1953861C2 (de) * 1969-10-25 1982-12-23 Fujisawa Pharmaceutical Co., Ltd., Osaka 7-Tetrazolylacetamido-3-thiomethyl-3-cephem-4- carbonsäuren
FR2068419A1 (en) * 1969-10-27 1971-08-27 Fujisawa Pharmaceutical Co Antibacterial cephalosporin compsns
BE758587A (fr) * 1969-11-17 1971-05-06 Fujisawa Pharmaceutical Co Procede de preparation de derives d'acide 7-aminocephalosporanique et nouveaux produits ainsi obtenus
US4010264A (en) * 1970-11-06 1977-03-01 Koninklijke Nederlandsche Gist-En Spiritusfabriek N.V. 7-[3-Substituted isoxazol-5-yl]-acetamido-cephalosporanic acids and their anti-bacterial use
US3687948A (en) * 1970-11-23 1972-08-29 Bristol Myers Co 7-{8 D-(a-AMINO-a-PHENYLACETAMIDO){9 -3-(4-METHYL-1,3-OXAZOL-2-YLTHIOMETHYL-3-CEPHEM-4-CARBOXYLIC ACID AND SALTS THEREOF
US3855213A (en) * 1971-02-18 1974-12-17 Smith Kline French Lab 3-heterocyclic thiomethyl-cephalosporins
US3867380A (en) * 1971-02-18 1975-02-18 Smithkline Corp 3-Heterocyclic thiomethylcephalosporins
US3972919A (en) * 1970-12-17 1976-08-03 Smithkline Corporation p-Hydroxymethylphenylglycine
YU36967B (en) * 1971-01-18 1984-08-31 Bristol Myers Co Process for the production of antibacterial agents
IE36221B1 (en) * 1971-04-21 1976-09-15 Ciba Geigy Ag Acylamino compounds and a process for their manufacture
US3757014A (en) * 1971-05-07 1973-09-04 Bristol Myers Co Ts 1,3,4 - oxadiazol-2-yl)thiomethyl)-3-cephem-4-carboxylic acid and sal7-(d-(alpha-amino-alpha-pheyle-acetamido)) - 3-(s-(5-hydroxymethyl -
US4025509A (en) * 1972-03-30 1977-05-24 Ciba-Geigy Corporation Aminopyridinium acetyl cephalosporanes
US3968226A (en) * 1972-06-14 1976-07-06 Smithkline Corporation 3-Heterocyclic thiomethylcephalosporins as antibacterial agents
US3855212A (en) * 1972-08-04 1974-12-17 Squibb & Sons Inc Cyanomethylth ioacetylcephalosporins
US3907784A (en) * 1972-09-11 1975-09-23 Lilly Co Eli 7-Halophenylthioacetamido cephalosporins
JPS49124574A (fr) * 1972-09-15 1974-11-28
US4060687A (en) * 1972-11-13 1977-11-29 Merck & Co., Inc. Cephalosporins having a 3-α substituted alkyl grouping
US3957768A (en) * 1972-11-14 1976-05-18 Smithkline Corporation 3-heterocyclicthiomethylcephalosporins
US4160829A (en) * 1972-12-22 1979-07-10 Gist-Brocades N.V. Antibacterial 1,2,4-oxadiazolylacetamido cephalosporins
US3898217A (en) * 1973-03-30 1975-08-05 American Home Prod 7-(1-Aminomethylcycloalkylcarboxamido)cephalosporanic
US4133882A (en) * 1973-05-11 1979-01-09 Smithkline Corporation 7-Hydroxyhalophenylacetamido-3-heterocyclicthiomethyl cephalosporins
US3957985A (en) * 1973-07-05 1976-05-18 Smithkline Corporation Mandelamidocephalosporins with improved properties
US3884914A (en) * 1973-07-05 1975-05-20 Smithkline Corp Mandelamidocephalosporins with improved properties
US4022895A (en) * 1973-08-01 1977-05-10 Smithkline Corporation Substituted phenylglycylcephalosporins
JPS5093989A (fr) * 1973-10-25 1975-07-26
US4071683A (en) * 1973-10-30 1978-01-31 Bayer Aktiengesellschaft Oxoimidazolidinylthiocarbonyl derivatives of ceph-3-em-4-carboxylic acids
AR205728A1 (es) * 1973-11-14 1976-05-31 Rhone Poulenc Sa Procedimiento para preparar ((dihidro-5,6-oxa)-(di) tiino-1,4-il-2) acetamido)-7 cefalosporina y sus sales
US3943126A (en) * 1973-11-15 1976-03-09 Eli Lilly And Company Process for acylating a 7-aminocephalosporin
US4379924A (en) * 1973-12-25 1983-04-12 Takeda Chemical Industries, Ltd. Cephalosporin derivatives
NZ176206A (en) * 1973-12-25 1978-03-06 Takeda Chemical Industries Ltd Cephalosporins
US3993758A (en) * 1974-01-18 1976-11-23 Beecham Group Limited Cephalosporin compounds
US4205166A (en) * 1974-02-20 1980-05-27 Fujisawa Pharmaceutical Co., Ltd. 7-Substituted-3-aminoalkyl-, acylaminoalkyl-, or hydroxyalkyl-substituted heterocyclic thiomethyl-3-cephem-4-carboxylic acid derivatives and preparation thereof
US3960849A (en) * 1974-03-13 1976-06-01 E. R. Squibb & Sons, Inc. Amino-1,2,4-oxadiazolyl-3-acetyl cephalosporins
US3929782A (en) * 1974-03-13 1975-12-30 Squibb & Sons Inc 1,2,4-Oxadiazolonylacetyl cephalosporins
US4160086A (en) * 1974-04-27 1979-07-03 Beecham Group Limited 3-Heterocyclicthio-7-α-carboxy 2-aryl acetamido cephalosporanic acid
US4091211A (en) * 1974-05-05 1978-05-23 Hoffmann-La Roche Inc. Cephalosporins
JPS612674B2 (fr) * 1974-06-20 1986-01-27 Meiji Seika Co
US3959259A (en) * 1974-07-08 1976-05-25 E. R. Squibb & Sons, Inc. 1,2,4-Oxadiazolonylacetyl penicillins
US3954745A (en) * 1974-09-12 1976-05-04 Eli Lilly And Company Process for preparing cefazolin
IE41697B1 (en) * 1974-09-27 1980-02-27 Rhone Poulenc Ind New cephalosporin derivatives their preparation and compositions containing them
US4182868A (en) * 1974-10-29 1980-01-08 Takeda Chemical Industries, Ltd. 7-Methoxycephalosporin derivatives
US4018759A (en) * 1974-12-03 1977-04-19 Smithkline Corporation 3-Heterocyclicthiomethylcephalosporins
US4286089A (en) * 1974-12-27 1981-08-25 Smithkline Corporation 7-Acyl-3-(substituted tetrazolyl thiomethyl)cephalosporins
US4093723A (en) * 1976-05-19 1978-06-06 Smithkline Corporation 7-Acyl-3-(sulfonic acid and sulfamoyl substituted tetrazolyl thiomethyl) cephalosporins
US3979384A (en) * 1975-03-20 1976-09-07 Merck & Co., Inc. C-3 Substituted cephalosporins
US4029782A (en) * 1975-04-28 1977-06-14 Eli Lilly And Company Cefazolin suspension for parenteral administration
US4126745A (en) * 1975-04-30 1978-11-21 Sankyo Company Limited 7-Methoxycephalosporin derivatives
DE2620094A1 (de) * 1975-05-12 1976-12-02 Takeda Chemical Industries Ltd Cephalosporinverbindungen und verfahren zu ihrer herstellung
CA1088049A (fr) * 1975-06-03 1980-10-21 Takashi Masugi Procedes d'obtention de derives d'acides alcanamido substitues en 3 et substitues en 7-3-cephem-4 carboxyliques
US4131672A (en) * 1975-06-09 1978-12-26 Eli Lilly And Company Method for treating methicillin resistant Staphylococcus aureus
US4049806A (en) * 1975-08-15 1977-09-20 Syntex (U.S.A.) Inc. Cephalosporin type antibacterials
US4048311A (en) * 1976-01-08 1977-09-13 Smithkline Corporation 7-Acyl-3-(sulfonic acid and sulfamoyl substituted tetrazolyl thiomethyl)cephalosporins
US4152433A (en) * 1976-03-12 1979-05-01 Fujisawa Pharmaceutical Co., Ltd. 2-Lower alkyl-7-substituted-2 or 3-cephem-4-carboxylic acid compounds and pharmaceutical compositions
US4034092A (en) * 1976-05-03 1977-07-05 Smithkline Corporation 7-Acyl-3-(carboxyalkyl and carbamoylalkyl substituted oxadiazolylthiomethyl) cephalosporins
US4220644A (en) * 1976-05-03 1980-09-02 Smithkline Corporation 7-Acylamino-3-(substituted tetrazolyl thiomethyl) cephalosporins
US4165429A (en) * 1976-06-28 1979-08-21 Yamanouchi Pharmaceutical Co., Ltd. 7α-METHOXY-CEPHALOSPORANIC ACID DERIVATIVES
FI771866A (fr) * 1976-06-28 1977-12-29 Fujisawa Pharmaceutical Co
DE2655949A1 (de) * 1976-12-10 1978-06-15 Gruenenthal Gmbh Neue cephalosporin- und penicillinderivate, verfahren zu deren herstellung und diese produkte enthaltende arzneimittel
US4316037A (en) * 1977-01-21 1982-02-16 American Home Products Corporation N-Benzyl and N-substituted benzyl tetrazole-5-carboxylic acids and the preparation thereof
GB1565941A (en) * 1977-02-08 1980-04-23 Toyama Chemical Co Ltd Process for producing 7-(substituted)amino-3-substituted thiomethyl cephem carboxylic acids
US4115645A (en) * 1977-05-10 1978-09-19 Eli Lilly And Company Decolorizing process for 7-amino-3-(((2-methyl-1,3,4-thiadiazol-5-yl)thio)methyl)-3-cephem-4-carboxylic acid
US4104470A (en) * 1977-06-03 1978-08-01 Eli Lilly And Company Crystallization process for cefazolin sodium
CH648317A5 (de) * 1977-06-10 1985-03-15 Yamanouchi Pharma Co Ltd 7alpha-methoxy-7betha-(1,3-dithietan-2- carboxamido)cephalosporansaeurederivate und verfahren zu ihrer herstellung.
US4229573A (en) * 1977-06-21 1980-10-21 Asahi Kasei Kogyo Kabushiki Kaisha 7α-Methoxycephalosporin derivatives
US4148998A (en) * 1977-10-04 1979-04-10 Yeda Research And Development Co., Ltd. Pyrrole cephalosporin derivatives
JPS6052711B2 (ja) * 1978-03-09 1985-11-20 旭化成株式会社 セフアロスポリン化合物の製法
EP0004570B1 (fr) * 1978-03-09 1982-04-14 Asahi Kasei Kogyo Kabushiki Kaisha Thiol-esters, procédé pour leur préparation, compositions pharmaceutiques les contenant et procédé pour la préparation de dérivés de céphalosporine en utilisant ces thiol-esters
US4314059A (en) * 1978-03-09 1982-02-02 Chisei Shibuya Process for preparing cephalosporin compounds
JPS6027677B2 (ja) * 1978-07-06 1985-06-29 富山化学工業株式会社 ７−置換又は非置換アミノ−３−置換チオメチルセフエムカルボン酸類の新規製造法
US4316016A (en) * 1979-03-19 1982-02-16 Bristol-Myers Company Cephalosporin intermediates
US4316017A (en) * 1979-03-19 1982-02-16 Bristol-Myers Company Cephalosporin intermediates
US4223135A (en) * 1979-03-19 1980-09-16 Bristol-Myers Company Production of cephalosporins
US4663461A (en) * 1980-08-29 1987-05-05 American Home Products Corporation Process for preparing 1-H-tetrazole-5-thiols
ES8300334A1 (es) * 1981-09-01 1982-11-01 Gema Sa Procedimiento para la preparacion de un acido 7-aminocefa- losporanido-3-substituido
HU188874B (en) * 1983-04-19 1986-05-28 Biogal Gyogyszergyar,Hu Process for producing new 7-acylamido-3-acylaminomethyl-ceph-3-eme-4-carboxylic acid derivatives and pharmaceutically acceptable salts thereof
US4576937A (en) * 1984-02-29 1986-03-18 Smithkline Beckman Corporation 7-D-Mandelamido-3(1-sulfomethyltetrazol-5-yl)thiomethyl-3-cephem-4-carboxylic acid monosodium salt
KR940000112B1 (ko) * 1990-07-05 1994-01-05 주식회사 대웅제약 신규의 3-치환 세펨화합물 및 그의 제조방법
US5318781A (en) * 1993-04-06 1994-06-07 Hoffmann-La Roche Inc. Absorption enhancement of antibiotics
GB9312853D0 (en) * 1993-06-22 1993-08-04 Euro Celtique Sa Chemical compounds
US5591776A (en) * 1994-06-24 1997-01-07 Euro-Celtique, S.A. Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV
US5922751A (en) * 1994-06-24 1999-07-13 Euro-Celtique, S.A. Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same
AU4527896A (en) * 1994-12-13 1996-07-03 Euro-Celtique S.A. Aryl thioxanthines
AU4527996A (en) * 1994-12-13 1996-07-03 Euro-Celtique S.A. Trisubstituted thioxanthines
US6025361A (en) * 1994-12-13 2000-02-15 Euro-Celtique, S.A. Trisubstituted thioxanthines
US5567698A (en) * 1995-02-15 1996-10-22 Bristol-Myers Squibb Company Pyridinium thiomethyl substituted chepholosporin derivatives
US6166041A (en) * 1995-10-11 2000-12-26 Euro-Celtique, S.A. 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma
US6075016A (en) * 1996-04-10 2000-06-13 Euro-Celtique S.A. 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity
IT1286520B1 (it) * 1996-12-03 1998-07-15 Antibioticos Spa Procedimento per la preparazione di intermedi utili nella sintesi di cefalosporine
WO2002085914A2 (fr) 2001-04-19 2002-10-31 Bioferma Murcia, S.A. Procede permettant de preparer des derives d'acide 3-cephalosporanique a l'aide de derives d'acide cetonique alpha
US7700581B2 (en) * 2007-01-31 2010-04-20 Guangzhou Baiyunshan Pharmaceutical Co., Ltd. Cephalosporin compounds comprising a C3 thio-methyl moiety substituted with N-containing heterocyclic group, and a C7 thiourea acetamido group, their preparations and uses thereof
CN104072517A (zh) * 2014-07-07 2014-10-01 江苏汉斯通药业有限公司 溴乙酰氨基头孢烷酸的生产工艺

Family Cites Families (4)

* Cited by examiner, † Cited by third party
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GB1012943A (en) * 1961-05-16 1965-12-15 Glaxo Lab Ltd Improvements in or relating to antibiotics
US3365449A (en) * 1964-07-23 1968-01-23 Fujisawa Pharmaceutical Co 7-(substituted thioacylamino) cephalosporanic acid and derivatives thereof
US3239515A (en) * 1965-01-18 1966-03-08 Lilly Co Eli Dithiocarboxylated cephalosporins
US3239516A (en) * 1965-01-18 1966-03-08 Lilly Co Eli Dithiocarboxylated cephalosporins

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2411839A1 (fr) * 1977-11-14 1979-07-13 Fujisawa Pharmaceutical Co Derives de l'acide cephalosporanique, procedes pour leur preparation et composition pharmaceutique les contenant
EP0070803A2 (fr) * 1981-07-16 1983-01-26 Ciba-Geigy Ag Dérivés d'aminotriazolylcéphalosporine antibiotiques et leur préparation
EP0070803A3 (fr) * 1981-07-16 1984-05-02 Ciba-Geigy Ag Dérivés d'aminotriazolylcéphalosporine antibiotiques et leur préparation
EP0076452A2 (fr) * 1981-09-30 1983-04-13 Ciba-Geigy Ag Dérivés de céphalosporine, procédé pour leur préparation et les compositions pharmaceutiques les contenant
EP0076452A3 (fr) * 1981-09-30 1984-09-05 Ciba-Geigy Ag Dérivés de céphalosporine, procédé pour leur préparation et les compositions pharmaceutiques les contenant

Also Published As

Publication number Publication date
DE1795838A1 (de) 1976-07-29
ES367294A1 (es) 1971-04-01
NL164560C (nl) 1981-01-15
SE369908B (fr) 1974-09-23
NL164560B (nl) 1980-08-15
CH527215A (de) 1972-08-31
CA928292A (en) 1973-06-12
DE1770168B2 (de) 1976-04-08
DE1770168A1 (de) 1972-03-16
ES367346A1 (es) 1971-05-01
ES352625A1 (es) 1970-01-01
GB1206305A (en) 1970-09-23
CH557381A (de) 1974-12-31
AT292193B (de) 1971-08-10
NL6805179A (fr) 1968-10-16
DE1795838B2 (de) 1979-07-26
US3516997A (en) 1970-06-23

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