FR3111795A1 - CARE KIT FOR KERATINIC MATERIALS - Google Patents

Abstract

The present invention relates to a kit, comprising: 1) a first kit composition comprising - at least one substrate, - at least one oil powder capable of forming an emulsion with an aqueous composition, - at least one additional hydrophilic and/or lipophilic powder, 2) a second kit composition comprising at least one aqueous composition capable of forming an emulsion with the oil powder, where the first kit composition and the second kit composition are placed separately from each other. Figure for the abstract: NONE

Description

CARE KIT FOR KERATIN MATERIALS

The present invention relates to a mask product comprising oil powders and hydrophilic powders and/or additional lipophilic powders, and is prepared by a kit treating keratin materials, in particular the skin. In addition, the current invention relates to the use of the latter for treating keratin materials, in particular the skin.

PRIOR ART

Masks are known to be very effective products and provide skin benefits such as moisturizing, moisturizing, whitening, cleansing, etc.

On the other hand, there are not many effective and comfortable masks.

There is a need for a mask product which is effective with a better stability tendency, a greater rate of dissolution of the active powders and easy impregnation. In particular, there is a need for a mask product, in which part of the juice could form an emulsion just before application to the skin with improved stability and speed of dissolution of the active powder(s) while offering, at the same time, the benefit of good skin conditioning, including better hydration, a better feeling of nutritious sensory touch and an improved feeling of skin comfort.

OBJECTIVES OF THE INVENTION

Accordingly, in one aspect, there is a need to provide some kind of mask product, wherein the mask comprises a kit, which separately comprises (1) a substrate, optionally, separately, oil powder(s) which may form an emulsion with aqueous compositions, and additional hydrophilic and/or lipophilic powder(s) and (2) an aqueous composition capable of forming an emulsion with the oil powder.

In another aspect, there is a need to provide some sort of ready-to-use mask product, in which, just prior to use, one mixes (1) the substrate part, including the oil powder(s) and the additional hydrophilic and/or lipophilic powders and (2) the aqueous composition which can form an emulsion with the oil powder optionally in the form of physical massage (eg manual massage), such that the mixture of the or oil powders, the additional hydrophilic and/or lipophilic powder(s) and the aqueous composition without surfactant (or with markedly less surfactant) form an emulsion; then the emulsion quickly permeates the substrate to form a mask product.

The present masks obtained have the following advantages:

1) A better tendency to stability and more hydration and nutritious feeling of sensory touch, thanks to a transformation into an emulsion just before use;

2) A more comfortable skin feeling, thanks to a reduction or absence of surfactant in the aqueous composition;

4) Faster dissolution of oil powders during use;

5) Easier impregnation compared to the normal emulsification phase;

6) In aqueous phase or in aqueous composition, there is less polyol density for better dispersion and great malleability during mixing with one or more active powders;

7) Improves the flowability of the oil powder(s) and reduces their tangling, this through the use of the additional hydrophilic/lipophilic powder(s);

8) Improves the stability of the oil powder(s), through the use of the additional hydrophilic/lipophilic powder(s).

DISCLOSURE OF INVENTION

The present inventors have discovered that a kit comprising:

1) a first kit composition comprising

- at least one substrate,

- at least one oil powder capable of forming an emulsion with an aqueous composition,

- at least one additional hydrophilic and/or lipophilic powder,

2) a second kit composition comprising at least one aqueous composition capable of forming an emulsion with the oil powder,

where the first kit composition and the second kit composition are placed separately from each other.

A subject of the present invention is also the use of the kit according to the present invention for treating keratinous materials, in particular the skin.

The present invention also relates to a process for treating keratin materials, in particular the skin, or for treating skin lesions, for preventing the formation of post-surgical adhesion or for filling or repairing osteocartilaginous defects, comprising the application of mask prepared from the kit of the present invention.

The present invention also relates to a process for preparing the kit according to the present invention, comprising the following steps:

- (1) providing the substrate as defined in the present invention;

- (2) providing the oil powder(s) as defined in the present invention;

- (3) providing the additional hydrophilic and/or lipophilic powder(s) as defined in the present invention;

and

- (4) mixing 1) the oil powder(s) and the additional hydrophilic and/or lipophilic powder, and 2) the aqueous composition, optionally with a physical massage (e.g. manual massage), to form an emulsion at room temperature and

wherein the emulsion obtained impregnates the substrate to form a mask or a dressing for skin lesions.

Other characteristics and advantages of the present invention will appear more clearly on reading the description and the examples which follow.

DETAILED DESCRIPTION OF THE INVENTION

Throughout the description, including the claims, the term "comprising a" must, unless otherwise stated, be understood as being synonymous with "comprising at least one". Furthermore, the expression “at least one” used in the present description is equivalent to the expression “one or more”.

Preferably, the “keratin material” according to the present invention is the skin. By “skin” is meant all of the skin of the body. Still preferably, the keratin material is the face or the neck, more particularly the face.

By “topical application”, is meant that the composition is applied or spread over the surface of the keratin materials, in particular at least over one area of the skin.

By "rinsing" is meant a composition which, after having been applied to the skin for a determined period, is removed from the skin by a rinsing composition such as water.

By "alkali metal" is meant an element located in Group IA of the periodic table, such as sodium, potassium, lithium or a combination of these elements, preferably sodium, potassium or a combination of these elements.

The term "water-soluble or water-dispersible" designates a compound which, when introduced into water at 25°C, at a mass concentration equal to 1%, makes it possible to obtain a macroscopically homogeneous and transparent solution, i.e. i.e. a solution having a maximum light transmittance value, at a wavelength equal to 500 nm, through a sample 1 cm thick, of at least 60% and preferably d at least 70%.

In the application, unless otherwise stated, the contents, parts and percentages are expressed by weight.

According to the present invention, the kit comprises a first composition and a second composition.

According to one embodiment, the part of the substrate and another part of the oil powder(s) as well as the additional hydrophilic and/or lipophilic powder in the first composition of the kit are placed separately from each other.

oil powder

The oil/fat powder is produced by any oil (or fat) compositions, for example, as defined below, which are acceptable in the cosmetic and pharmaceutical field.

According to one embodiment of the present invention, the oil (or fat) compositions can be produced from vegetable oil(s), which are collectively extracted from vegetable seeds, pulp, fruits and other parts, for example, selected from the group of all plant essential oils.

According to one embodiment of the present invention, the oil (or fat) compositions can be produced from animal oil(s), which are collectively extracted from the animal body or its secretions, for example, from the group of pigs, fish, chickens, cows and other animals.

Examples of oils/fats for use in the fat composition described above are vegetable oils and animal oils/fats, more particularly vegetable oils such as safflower oil, olive, cottonseed oil, canola/rapeseed oil, corn oil, peanut oil, walnut oil, soybean oil, flaxseed oil, l perilla oil, palm oil, palm kernel oil, sunflower oil, sesame oil, rice oil, cottonseed oil, cocoa butter, oil tung oil, castor oil, olive oil, canola oil, hemp oil, Vita E, etc., such as butyrospermum parkii butter (shea butter), wheat germ and coconut oil; animal oils (or fat) such as lard fat, beef fat, tallow fat, duck fat, butter fat, fish fat, etc.; as well as their hydrogenated oils, their fractionated oils and their transesterified oils.

According to one embodiment of the present invention, the raw materials of the oil (or fat) compositions are preferably fats and vegetable oils whose fatty acid residues, for example, for more than 90% by weight , which contain 16 to 22 carbon atoms, linear or branched, saturated or unsaturated.

According to one embodiment of the present invention, the oil (or fat) powder, comprising:

- oil (or fat) composition(s), consisting essentially of a mixture of mono-, di- and triglycerides, and of a mixture of the latter, optionally containing all of the constituent fatty acids;

- one or more emulsifier(s), whose HLB value is preferably equal to or greater than 7, preferably from 7 to 20, and in particular from 11 to 16;

- optionally, the powder forming bases, for example, include carbohydrates such as monosaccharides, oligosaccharides and polysaccharides, proteins and peptides;

- optionally, binder(s) or diluent(s),

- possibly, stabilizers.

According to one embodiment of the present invention, the oil (or fat) composition of the invention consists essentially of a mixture of mono-, di- and triglycerides, where more than 90% of the weight of the fatty acid residues incorporated in the glycerides preferably contain 14 to 22 carbon atoms, preferably produced from vegetable fats, or produced from hardened vegetable oils or fractions thereof. Mono-, di- and triglycerides of fatty acids are, for example, mono-, di- and triglycerides, the fatty acid portion of which comprises at least a portion of the following fatty acids:

- myristic acid

- pentadecyl acid

- palmitic acid CH ₃ (CH ₂ ) ₁₄ COOHC

- heptadecylic acid CH ₃ (CH ₂ ) ₁₅ COOHC

- stearic acid CH ₃ (CH ₂ ) ₁₆ COOHC

- nonadecanoic acid CH ₃ (CH ₂ ) ₁₇ COOHC

- arachidic acid CH ₃ (CH ₂ ) ₁₈ COOHC

- heneicosanoic acid CH ₃ (CH ₂ ) ₁₉ COOHC

- behenic acid CH ₃ (CH ₂ ) ₂₀ COOHC

- tricosanoic acid CH ₃ (CH ₂ ) ₂₁ COOHC

- lignoceric acid CH ₃ (CH ₂ ) ₂₂ COOHC

- myristoleic acid CH ₃ (CH ₂ ) ₃ CH=CH(CH ₂ ) ₇ COOH

- palmitoleic acid

- vaccenic acid

- gadoleic acid

- sapienic acid

- oleic acid

- trans-oleic acid

- eicosenoic acid

- erucic acid

- erucylacetic acid (selacholeic acid)

- gondoic acid

- hexadecatrienoic acid (HTA)

- linolenic acid

- α-linolenic acid (ALA)

- stearidonic acid (SDA)

- eicosatrienoic acid (ETE)

- eicosatetraenoic acid (ETA)

- eicosapentaenoic acid (EPA)

- heneicosapentaenoic acid (HPA)

- docosapentaenoic acid (DPA)

- docosahexaenoic acid (DHA)

- meat acid

- vaccenic acid

and their mixtures.

According to an embodiment of the present invention, the emulsifier, which emulsifies the oil powder well when meeting the aqueous phase and makes the oil powder stable in the oil powder manufacturing process, has preferably an HLB value of 7 or more, more preferably 7 to 20, especially 11 to 16. The "HLB value" can be calculated according to the Griffin equation (Bibliography: J. Soc. Cosmet. Chem., 1 , 311(1949)). Among these emulsifiers are polyglycerin fatty acid esters, sorbitan fatty acid esters, polyoxyethylene sorbitan fatty acid esters, propylene glycol fatty acid esters, sucrose, lecithin, lecithins such as enzymatically decomposed lecithin, monofatty acid esters of glycerin and organic acid esters of monoglycerides such as acetylated monoglyceride, lactylated monoglyceride and citrated monoglyceride. These emulsifiers can be used alone or in combination of two or more. The use of one or two or more polyglycerin fatty acid esters, sucrose fatty acid esters, sorbitan fatty acid esters, lecithins and fatty acid esters polyoxyethylene sorbitan is preferable from the viewpoint of emulsion stability of Component (A). Of these, sucrose fatty acid esters and polyglycerine fatty acid esters are particularly preferred. The HLB value when two or more emulsifiers are used in combination can be determined from the weighted average of the HLB values of these emulsifiers.

According to one embodiment, the emulsifier(s) and/or the surfactant(s) are only included in the oil powder(s).

According to one embodiment of the present invention, powder forming bases, where examples of carbohydrates include sugar alcohols such as glucose, fructose, maltose, lactose, sucrose and trehalose, starches, polysaccharide thickeners and gum substances. Starch, corn starch, potato starch, tapioca starch, dextrin, cyclodextrin, oxidized starch, starch ester, starch ether, l Cross-linked starch, alpha starch or octenylsuccinate ester, or processed starch obtained by treating starch with acid, heat or enzyme, is used as needed. Of these, dextrin is preferred, as it has a dextrose equivalent (hereinafter abbreviated "DE") (percentage (%) of reducing sugar, calculated in terms of glucose, as dextrin) of 8 to 45, preferably 10 to 30, with 12 to 25 being particularly desired. One or a mixture of two or more algae, seed, micro-organism or resin derivatives can be used as thickening gummed substance based on polysaccharide. Specific examples include pullulan, sodium alginate, xanthan gum, guar gum, locust bean gum, tragacanth gum, tamarind gum, carrageenan, furcellaran, arabic, gellan gum, psyllium, curdlan, konjac mannan, pectin, agar, and cellulose derivatives such as carboxymethylcellulose.

According to one embodiment of the present invention relating to powder forming bases, wherein examples of proteins or peptides include proteins such as those derived from animals or plants such as milk, egg, meat , wheat, rice, soy and maize, and those obtained by separation or decomposition of the proteins described above, a mixture of more than one of these proteins, and complexes (lipoproteins) of these proteins with a lipid . Specific examples include casein, whey, gelatin, skim milk, soy globulin, egg albumen, and egg yolk protein.

According to an embodiment of the present invention, relating to the powder forming bases, in which the powder forming bases can be used either alone or in combination of two or more, but the use of dextrin and the protein in combination is preferable from the viewpoint of the emulsion stability of the glyceride mixture and the storage stability of the oil/fat powder, the use of dextrin having a DE of 8 to 45 and casein in combination is particularly preferable.

The term “diluent”, for example as a filler, designates any form of particles, whatever the temperature of the composition prepared, the particles not being soluble in the medium of the composition. The filler can be used to adjust the rheology and composition of the structure. The nature and amount of the solid material is determined by the desired mechanical and structural properties of the composition. Mention may be made, as examples of fillers, of: talc, mica, silica, kaolin, sericite, polyamide powder, polyethylene powder, polytetrafluoroethylene powder, polymethyl methacrylate powder, polyurethane, starch powder and silicone beads.

The term "binder" designates any form of binder that can be used in powders, for example, selected from at least one polymer, such as maltodextrin, at least one fatty substance-based material, and mixtures of these last, sugars such as xylitol, trehalose and others.

According to one embodiment of the present invention, the oil powder used in the present invention is commercially available, for example, with products bearing the trade name Akofine (e.g. Akofine P, Akofine R, Akofine FP) marketed by AAK.

According to one embodiment of the present invention, the stabilizer may be one or more salt(s) of inorganic acid(s) or of organic acid(s), for example, salt(s) (s) alkali(s) of inorganic acid(s) or organic acid(s), such as sodium citrate. Surfactants can also be used as stabilizers in oil/fat powder.

According to an embodiment of the present invention, the oil powder can also comprise ionic surfactants, which can be anionic or cationic.

Mention should be made more particularly, as representative of the anionic surfactants: salts of C 18-C 30 fatty acids, in particular those derived from amines, such as triethanolamine stearate and/or 2-amino stearate; 2-methylpropane di-1,3-ol; polyoxyethylene fatty acid salts, in particular those derived from amines or from alkaline salts and mixtures thereof; phosphoric esters and their salts, such as "DEA oleth-10-phosphate" (Crodafos N 10N from the company Croda); sulfosuccinates such as "Disodium PEG-5 laurylcitrate (succinate" and "Disodium ricinoleamido MEA-sulfosuccinate" - alkyl ether sulfates such as sodium lauryl ether sulfate; isethionates; acylglutamates such as "disodium hydrogen tallow glutamate" (AMISOFT HS-21 R marketed by the company AJINOMOTO) and mixtures thereof Triethanolamine stearate and/or 2-amino-2-methylpropane-1,3-diol stearate are particularly suitable for the invention. by a simple mixture of stearic acid with triethanolamine and/or 2-amino-2-methylpropane di-1,3-ol Mention may be made, as surfactants which can be used in the present invention, in particular, of the salts , in particular alkali metal salts, in particular sodium salts, ammonium salts, amine salts, amino alcohol salts or alkaline earth metal salts, for example magnesium, of the following types: alkyl sulphates, sulf alkyl ether ates, alkyl amido ether sulphates, polyalkyl ether sulphates, monoglyceride sulphates; alkyl sulfonates, alkylamide sulfonates, alkylaryl sulfonates, α-olefin sulfonates, paraffin sulfonates, alkyl sulfosuccinates, alkyl ether sulfosuccinates, alkylamide sulfosuccinates, alkyl sulfoacetates; acylsarcosinates and acylglutamates, the alkyl and acyl groups of these compounds containing from 6 to 24 carbon atoms and the aryl group preferably denoting a phenyl or benzyl group. It is also possible to use C6-C24 alkyl esters of polyglycosidecarboxylic acids such as alkyl glucoside citrates, alkyl polyglycoside tartrates, alkylated polyglycoside sulfosuccinates; alkyl sulfosuccinamates, acyl isethionates and N-acyltaurates, the alkyl or acyl groups of all these compounds comprising from 12 to 20 carbon atoms. Among the anionic surfactants which can be used further, mention may also be made of acyl lactylates in which the acyl group comprises from 8 to 20 carbon atoms.

Special mention may be made of the following as representatives of cationic surfactants: alkylimidazolidiniums such as isostearyl ethyldimonium ethosulfate; ammonium salts such as N,N,N-trimethyl-1-docosanaminium chloride; (Behentrimonium chloride).

The surfactants described above can be used alone or in the form of a mixture.

According to an embodiment of the present invention, the addition of an antioxidant to the oil/fat powder of the present invention is possible in order to prevent deterioration due to oxidation of glycerides, thereby improving the stability. storage and taste stability. Examples of antioxidants include tocopherols, L-ascorbic acid or its salts, L-ascorbyl fatty acid esters, natural antioxidant compounds, butylated hydroxytoluene (BHT), butylated hydroxyanisole (BHA), tert-butylhydroquinone (TBHQ) and phospholipid.

For tocopherol, preference is given to that soluble in glycerides and α, β, γ, or δ tocopherol or a mixture of the latter. Examples of commercially available tocopherols include "E MIX D", "E MIX 80" (both marketed by Eisai), "MDE-6000" (marketed by Yashiro), "E Oil-400 “, “E Oil-600”, “E Oil-805” (marketed by Riken Vitamin) and “MIXED TOCOPHEROLS MTS-50” (marketed by ADM).

For the L-ascorbyl fatty acid ester, glyceride-soluble esters are preferred, including higher fatty acid esters, for example, preferably those having a C12-22 acyl group, with particular preference for the L-ascorbyl palmitate and L-ascorbyl stearate.

As a natural antioxidant component, rosemary extract and water-soluble tea extracts (catechins) are particularly preferred because they have high antioxidant property. Rosemary extract is obtained by extracting rosemary leaves, the latter belongs to the labiate family, with an organic solvent. As the rosemary extract, one which is soluble in glycerides is preferred. The extracts described above can be used with an organic solvent, oleoresin preparations using the extract, preparations using the constituent element of rosemary extract such as romanol, carnosol and isorosmanol, and these extracts are subsequently subjected to a deodorization treatment by pressure reduction or column absorption. Of these extracts, preference will be given to deodorized extracts having a residual amount of solvent of 20 ppm or less, taking into account the taste. Examples of commercially available rosemary extract include "Herbalox brand type O", "same type HT-O", "same type 25", "Duolite NMH", "same NM-1" (all being marketed by Kalsec), “Leomeal E”, “idem IO” (marketed by Lion).

Water-soluble tea extracts (catechins) are concentrates of the extract obtained by extracting green tea leaves, semi-fermented tea or fermented tea with a solvent, water or water hot, followed by filtration and drying. The term "catechins" is a generic name including non-epi catechins such as catechin, gallocatechin, catechin gallate and gallocatechin gallate and epi catechins such as epicatechin, epigallocatechin, epicatechin gallate and epicallocatechin gallate.

Glyceride-soluble or dispersible catechins are preferred. Among the catechins available on the market are "Polyphenon" (product of Mitsui Norin Group), "Thea-flan" (product of Itoen), "Sunphenon" (product of Taiyo Chemical), "Sun-oolong" (product of Suntory) and “YMC Catechin” (product of YMC).

As the natural antioxidant component other than rosemary extract and water-soluble tea extract described above, there may be exemplified apple polyphenol ("Applephenone", product of San-Ei Gen FFI ) and sunflower seed extract (“Héliant”, a product of DAINIPPON INK AND CHICALS).

According to one embodiment of the present invention, the oil composition(s) is/are present in the oil powder in an amount of between 10% and 60% by weight, preferably between 20% and 50 % by weight, with a particular preference of 30% to 35% by weight, with respect to the weight of the oil powder.

According to one embodiment of the present invention, the emulsifier/surfactant is present in the oil powder in an amount ranging from 0.1% to 15% by weight, preferably from 0.5% to 10% by weight. , more preferably from 1% to 5% by weight, with respect to the weight of the oil powder.

According to an embodiment of the present invention, the powder forming bases are present in the oil powder in an amount between 2% and 50% by weight, preferably 5% to 40% by weight, more preferably from 10% to 30% by weight, with respect to the weight of the oil powder.

According to one embodiment of the present invention, the binder(s) or bulking agent(s) are present in the oil powder in an amount ranging from 5% to 60% by weight, preferably 10% to 50% by weight, more preferably from 20% to 40% by weight, with respect to the weight of the oil powder.

According to one embodiment of the present invention, the oil powder is in an amount between 20% and 90% by weight, or between 30% and 80% by weight, or between 40% and 60% by weight, or between 60% and 40% by weight, or between 70% and 30% by weight, with respect to the total weight of the oil powder(s) and the hydrophilic and/or lipophilic powder(s).

According to one embodiment of the present invention, the oil powder comprises the following elements, in percentage by weight. Starch-like materials (e.g. sodium starch octenylsuccinate, etc.) 10-30% Saccharides (eg, trehalose, etc.) 0-40% Glyceryl fatty acid salt (e.g. glyceryl stearate citrate, glyceryl monostearate, sodium stearoyl lactylate, etc.) 1-5% Oil (e.g. canola oil, etc.) 30-35% Powder Forming Bases (e.g. Dextrin(s), Maltodextrin(s), etc.) 0-45% Stabilizer (such as salt, salt or salts of inorganic acid(s) or organic acid(s), e.g. sodium citrate) quantum satisfied

According to one embodiment of the present invention, the oil powder comprises the following elements, in percentage by weight. Sodium Starch Octenylsuccinate 25.9% Glyceryl Stearate Citrate 0.46% Glyceryl Monostearate 0.78% Sodium stearoyl lactylate 0.06 Canola oil 29.2% Butyrospermum parkii butter 5.1% Maltodextrin 38.5%

Especially in the case where the glycerides have a low stability against oxidation or when the oil/fat powder is necessary to have a high storage stability, it is preferable to use two or more of the antioxidants described above in combination, compared to the use of only one in greater quantity. A mixture of tocopherol, L-ascorbyl fatty acid ester and a plant-derived antioxidant is particularly preferred as the antioxidant.

The oil powder(s) may comprise at least one cosmetic or dermatological active substance. The following elements can be used in compositions of the present invention, the dermatological, hygienic or pharmaceutical active substance can consist of the following elements: moisturizers, vitamins (C, A, E, F, B or PP), essential fatty acids, essential oils, ceramides, sphingolipids, fat-soluble sunscreens or sunscreens in the form of nanoparticles, and the particular therapeutic dermatological active substance (protective agents, antibacterial agents, anti-wrinkle agents, etc.).

Oil powders may additionally include ingredients commonly used in cosmetics and pharmaceuticals, such as thickeners, surfactants, trace elements, moisturizers, softeners, release agents, fragrances, acidifying agents or basifiers, preservatives, antioxidants, UV stabilizers or colorants, or mixtures thereof.

The oil powders used in the present invention may be prepared in any manner known to those skilled in the art, for example, by removing water, selected from spray drying, spray freezing, freeze drying, spray freezing and extrusion granulation.

Water-soluble vitamins can additionally be used as an active agent in the composition of the first kit or oil powder. Useful examples of vitamin include vitamin C (ascorbic acid), vitamin B group (eg vitamin B5 (panthenol), vitamin B3 (niacinamide), vitamin B1 and vitamin B2), nicotinic acid , folic acid, pantothenic acid, derivatives of these vitamins (in particular esters) and mixtures thereof, particularly vitamin C, preferably in dry form.

Among other things, vitamin C in dry form is preferably used.

Vitamins which can be used in the present invention can be represented, for example, by the products sold under the name ASCORBIC ACID 100 MESH, available from CSPC WEISHENG PHARMACEUTICAL, or from BASF.

Useful derivatives of the water-soluble vitamins preferably include 3-o-ethyl ascorbic acid, ascorbyl glucoside or a mixture of these vitamins.

The first kit composition or oil powder of the present invention may further comprise ferulic acid.

Ferulic acid is commonly found in giant fennel, coffee, apple, artichoke, peanut, and orange seeds, and in the seeds and cell walls of commelinid plants (such as rice , wheat, oats and pineapple).

Mention may be made of a product, such as, for example, ORYZA FERULIX, available from ORYZA OIL & FAT CHEMICAL.

Additional hydrophilic and/or lipophilic powder

The first composition of the kit of the present invention further comprises at least one additional hydrophilic and/or lipophilic powder.

Adding hydrophilic and/or lipophilic powder can improve oil powder flow, reduce tangling and improve oil powder stability.

Additional hydrophilic and/or lipophilic powders can be selected from silica, cellulose-based compounds (such as cellulose and its derivatives), nylon (such as nylon-6 and nylon-12) and its derivatives, of silicone, of polydimethylsiloxane (PDMS) or of any combination thereof.

According to the present invention, the expression “cellulose-based compound” denotes any polysaccharide compound bearing in its structure linear sequences of anhydroglucopyranose (AGU) residues linked together by β(1,4) bonds. The repeating unit is the cellobiose dimer. AGUs are in chair conformation and have 3 hydroxyl functions: 2 secondary alcohols (in positions 2 and 3) and a primary alcohol (in position 6). The polymers thus formed combine by intermolecular bonds of the hydrogen bond type, thus giving the cellulose a fibrillar structure (approximately 1500 molecules per fiber).

The degree of polymerization varies considerably depending on the origin of the cellulose; its value can range from a few hundred to several tens of thousands.

Cellulose hydroxyl groups can partially or totally react with various chemical reagents to give cellulose derivatives with intrinsic properties. Cellulose derivatives can be anionic, cationic, amphoteric or nonionic. Among these derivatives, a distinction is made between cellulose ethers, cellulose esters and cellulose ester ethers.

Among the nonionic cellulose ethers, mention may be made of alkylcelluloses such as methylcelluloses and ethylcelluloses; hydroxyalkylcelluloses, such as hydroxymethylcelluloses, hydroxyethylcelluloses and hydroxypropylcelluloses and mixed hydroxyalkylcelluloses such as hydroxypropylmethylcelluloses, hydroxyethylmethylcelluloses, hydroxyethylethylcelluloses and hydroxybutylmethylcelluloses.

Among the anionic cellulose ethers, mention may be made of the carboxyalkylcelluloses and their salts. By way of example, mention may be made of carboxymethylcelluloses, carboxymethylcelluloses and carboxymethylhydroxy-ethylcelluloses and their sodium salts.

Among the cationic cellulose ethers, mention may be made of crosslinked or non-crosslinked quaternized hydroxyethyl celluloses.

The quaternizing agent can in particular be glycidyltrimethylammonium chloride or a fatty amine such as laurylamine or stearylamine. Another cationic cellulose ether which may be mentioned is hydroxyethylcellulosehydroxypropyltrimethylammonium.

Quaternized cellulose derivatives include:

- quaternized celluloses modified with groups comprising at least one fatty chain, such as alkyl, arylalkyl or alkylaryl groups comprising at least 8 carbon atoms, or mixtures thereof,

- quaternized hydroxyethyl celluloses modified with groups comprising at least one fatty chain, such as alkyl, arylalkyl or alkylaryl groups comprising at least 8 carbon atoms or mixtures of the latter.

The alkyl radicals supported by the quaternized celluloses or the hydroxyethylcelluloses above preferably contain from 8 to 30 carbon atoms. The aryl radicals preferably designate the phenyl, benzyl, naphthyl or anthryl groups.

Examples of quaternized alkylhydroxyethylcelluloses containing C8-30 fatty chains include the products Quatrisoft LM 200, Quatrisoft LM-X 529-18-A, Quatrisoft LM-X 529-18B (C12 alkyl) and Quatrisoft LM-X. 529-8 (C18 alkylated) marketed by the company Amerchol and the products Crodacel QM, Crodacel QL (C12 alkyl) and Crodacel QS (C18 alkyl) marketed by the company Croda.

Among the cellulose derivatives, mention may also be made of:

- celluloses modified with groups comprising at least one fatty chain, for example hydroxyethylcelluloses modified with groups comprising at least one fatty chain, such as alkyl groups, in particular C8-22, arylalkyl and alkylaryl groups, such as Natrosol Plus Grade 330 CS (C16 alkyl) marketed by Aqualon,

- Cellulose modified with groups of polyalkylene glycol alkylphenyl ethers, such as the product Amercell Polymer HM-1500 (ether of polyethylene glycol nonylphenyl (15) ether) marketed by the company Amerchol.

Cellulose esters include inorganic cellulose esters (cellulose nitrates, sulfates, phosphates, etc.), organic cellulose esters (monoacetates, triacetates, amidopropionates, acetate butyrates, cellulose acetatepropionates and acetatetrimellitates, etc.) and mixed organic/mineral esters of cellulose, such as cellulose acetatebutyrate sulfates and cellulose acetatepropionate sulfates. Among the cellulose ester ethers, mention may be made of hydroxypropylmethylcellulose phthalates and ethylcellulose sulphates.

The cellulose-based compounds of the present invention can be selected from unsubstituted celluloses and substituted celluloses. Cellulose and derivatives are represented, for example, by the products marketed under the names Avicel® (microcrystalline cellulose, MCC) by the company FMC Biopolymers, under the name Cekol (carboxymethylcellulose) by the company Noviant (CP-Kelco), under the name Akucell AF (sodium carboxymethylcellulose) by Akzo Nobel, under the name Methocel™ (cellulose ethers) and Ethocel™ (ethylcellulose) by Dow, and under the names Aqualon® (carboxymethylcellulose and sodium carboxymethylcellulose), Benecel® ( methylcellulose), Blanose™ (carboxymethylcellulose), Culminal® (methylcellulose, hydroxypropylmethylcellulose), Klucel® (hydroxypropylcellulose), Polysurf® (cetylhydroxyethylcellulose) and Natrosol CS (hydroxyethylcellulose) by Hercules Aqualon.

Cellulose and their derivatives, in particular methylcellulose, hydroxyalkylcellulose, ethylhydroxyethylcellulose and carboxymethylcellulose.

According to an embodiment of the present invention, the additional hydrophilic and/or lipophilic powder can be coated with the used oil powder so that the oil powder disperses significantly better and dissolves much faster.

According to one embodiment of the present invention, the additional hydrophilic and/or lipophilic powder is in an amount of between 1% and less than 100% by weight, or between 5% and 60% by weight, or between 10% and 50 % by weight, even from 20% to 40% by weight, based on the total weight of the oil powder and the additional hydrophilic and/or lipophilic powder.

Substrate(s)

All types of substrates suitable in the cosmetic field can be a substrate used in the present invention. In particular, the substrate is selected from the following group:

(1) a water insoluble substrate which is a cosmetically and pharmaceutically acceptable substrate and/or

(2) a gel substrate comprising:

※A) a first tissue composition comprising at least one gel-forming agent which is a water-soluble salt, and

※B) a second tissue composition comprising

- B1) at least one aqueous phase and

- B2) at least one water-soluble gelatinizing agent, which is gelatinizable with the polyvalent metal ion and

- B3) optionally, at least one water-soluble chelating agent of the polyvalent metal ion,

where the first tissue composition and the second tissue composition are placed separately from each other.

water insoluble substrate

For the purposes of the invention, the term "water insoluble" means that the substrate is not soluble in water and does not disintegrate upon immersion in water.

The material of the substrate according to the present invention is not limited and therefore any material can be used for the preparation; that is, all types of acceptable cosmetic and pharmaceutical substrates can be the water-insoluble substrate. Two or more materials can also be used.

The water-insoluble substrate is a woven or nonwoven fabric made of a fiber selected from natural fibers, semi-natural fibers and synthetic fibers, for example, a woven or nonwoven fabric made of a fiber at least one water-insoluble alginate alone or together with one or more other fibers selected from natural fibers such as cotton, pulp, bamboo and cellulose fibers such as viscose rayon fibers, synthetic fibers such as polyester fibers, polyethylene terephthalate fibers, polyethylene fibers and polypropylene fibers or a mixture of these fibers. Two or more fibers selected from the above fibers or more may be used in combination.

Furthermore, it may be a film or a sheet of at least one product selected from synthetic polymers such as polyethylenes and polyvinyl alcohols, semi-synthetic polymers such as biocelluloses and alginates , and natural polymers such as polysaccharides (eg carrageenan and xanthan gum), mucopolysaccharides (eg hyaluronic acid and sodium hyaluronate), polypeptides (eg γ-polyglutamic acid) and proteins (eg gelatin and collagen ). The film or sheet can be in the form of a gel or jelly which can be transparent, translucent or opaque. Two or more substances selected from the aforementioned substances may be used in combination.

In one embodiment, the water-insoluble substrate is a substrate that comprises a plurality of fibers, wherein said fibers comprise a core comprising at least one polymeric material and a body coating comprising at least one hydrophilic polymer. Advantageously, said fibers are entangled. In one embodiment, said fibers are conjugate fibers comprising a body composed of at least two polymeric materials and a body coating comprising at least one hydrophilic polymer. In one embodiment, said body comprises at least one polymeric material forming the core of the body, at least one polymeric material forming a sheath of the body and at least one hydrophilic polymer forming the coating of said body. In one embodiment, said fibers are bi-component fibers (fiber body) with a hydrophilic polymeric coating (body coating). In one embodiment, said body comprises two polymers, preferably with both polymers in the cross section of the same fiber. In one embodiment, the cross-sectional body polymers of the fiber are arranged side by side as a sheath/core. In one embodiment, the body polymers in the cross section of the fiber are arranged as concentric or eccentric sheath/core. In a preferred embodiment, said fiber comprises a body having a higher melting point (melting temperature) than the sheath of the body. Within the meaning of the invention, the melting point corresponds to the temperature of the most endothermic peak observed by the thermal analysis (DSC) described in standard ISO 1 1357-3. The melting point can be measured using a differential scanning calorimeter (DSC), for example the calorimeter sold under the name "MDSC 2920" by TA Instruments. In one embodiment, the melting point of the core of the body is greater than 150°C. In one embodiment, the melting point of the core of the body is greater than 230°C. In one embodiment, the melting point of the core body is between 150°C and 300°C. In one embodiment, the melting point of the core body ranges from 230°C to 300°C. In one embodiment, the melting point of the body sheath is less than 230°C. In one embodiment, the melting point of the body sheath is less than 150°C. In one embodiment, the melting point of the body sheath is between 100°C and 230°C. In one embodiment, the melting point of the body sheath is between 100°C and 150°C. In a preferred and specific embodiment, said fiber comprises a body consisting of a first polymer forming the core of the body, said body consisting of a second polymer forming the sheath of the body, in which said first polymer has a melting point higher than the second polymer. Non-limiting examples of polymers which can be used as one of the polymers of said body are selected from the group consisting of Polyester, derivatives of polyester, Nylon6, Nylon 66, Polypropylene, Polyethylene, polylactic acid, polystyrene and any mixture of these polymers. In one embodiment, non-limiting examples of polymers that can be used as one of said body polymers are selected from the group consisting of low density polyethylene (LDPE), high density polyethylene (HDPE) polypropylene (PP), ultra-high molecular weight polyethylene (UHMW), polypropylene (PP), polyvinylidene fluoride (PVDF), polytetrafluoroethylene (PTFE) and polyetherosulfone (PES) and any mixtures of these substances. In one embodiment, the core of the body is selected from polypropylene (PP) and the sheath of the body is selected from polyethylene (PE), said polypropylene having a higher melting point than said polyethylene. Some common examples of the combination of two fibers are given below:

• Polyester core (melting point 250°C) with copolyester sheath (melting points from 110°C to 220°C)

・Polyester core (melting point 250°C) with polyethylene sheath (melting point 130°C)

・Polypropylene core (melting point 175°C) with polyethylene sheath (melting point 130°C)

Preferred hydrophilic polymers are those which provide high absorbency, and preferably absorb greater than 30 times, or even preferably greater than 50 times, their dry weight when dipped into an aqueous liquid formulation. The hydrophilic polymer is preferably selected from the group consisting of any commercially available hydrophilic polymer. Non-limiting examples for polymers composed of acrylic acid, methacrylic acid, glutamic acid, β-carboxyethyl acrylate, maleic acid, maleic acid monoesters, etc., in a mode of realization ; said hydrophilic polymers are acrylate polymers. Acrylate polymers containing carboxyl groups are commercially available. In a particular embodiment, said hydrophilic polymer is poly(acrylic acid). For example, poly(acrylic) acid can be obtained, inter alia, from Polycryl AG, Bohler, Postfach, CH-6221 Rickenbach, Switzerland (trade name: Polycryl); Stockhausen, 2401 Doyle St., Greensboro, C.N., 27406-2911; and BFGoodrich, Four Coliseum Center, 2730 West Tyvola Street, Charlotte, N.C. Carbopol). The polymer of the invention (for the body or the coating of the body) refers to a polymer made on the basis of a single monomer or of two or more monomers. Therefore, the term polymer is broad within the meaning of the invention and includes, unless otherwise indicated, homopolymers and copolymers. The copolymers denote random and alternating copolymers, without limitation, except that they are suitable for the invention. The polymer of the invention can be linear or branched. In a specific embodiment, the fibers of the invention comprise a PP core and a PE sheath in the body and poly(acrylic) acid in the body coating. In a particular embodiment, the fibers of the invention consist of a body consisting of a PP core, a PE sheath and a body coating consisting of poly(acrylic acid).

The folded sheet according to the present invention may consist of two or more layers. Thus, for example, the substrate may be a laminated substrate comprising two or more stacked layers. If a laminated substrate is used, the material of each stacked layer may be the same or different. For example, the laminated substrate can be prepared by laminating the above film or sheet from a synthetic polymer, a semi-synthetic polymer and/or a natural polymer onto the above woven or nonwoven fabric. -above.

The substrate can be formed into a wide variety of shapes, such as flat folds, thick pads, thin sheets of irregular thickness, depending on the desired use and the characteristic of the mask. The substrate is generally designed to conform to the area of the skin to which topical application is desired. For example, when the mask is applied to the face, the substrate is designed to match the shape of the face, avoiding the eye, nostril and mouth areas if necessary. Non-limiting examples of the substrates useful in the present invention are described, for example, in patent application WO 02/062132 or EP 2489286A.

These water-insoluble substrates or masks with holes, perforation lines or cut lines formed which can be obtained by cutting desired holes on the conventional masks which are available in the market. Mention may be made of suitable commercially available masks such as NA60RP70 from Beijing Dongfang Dayuan Non-wovens Fabric Co., Ltd. Then, by using the ZG-10T die cutting machine of Hangzhou Zhiling Co. Ltd to cut the desired holes on the mask, the water-insoluble substrates of the present invention are obtained.

gel substrate

First of all, the gel substrate according to the present invention comprises:

※A) a first substrate composition comprising at least one gel-forming agent which is a water-soluble salt and

※B) a second substrate composition comprising:

- B1) at least one aqueous phase and

- B2) at least one water-soluble gelatinizing agent, which is gelatinizable with the polyvalent metal ion and

- B3) optionally, at least one water-soluble chelating agent of the polyvalent metal ion,

where the first substrate composition and the second substrate composition are placed separately from each other.

According to one embodiment of the present invention, the gel-forming agent of the present invention may be a water-soluble polyvalent metal algin compound, for example, an alkali metal algin compound.

The term “alginic alkali metal compound” designates in particular alginic acid salts of alkali metal (alginates) or alkali metal salts of derivatives of alginic acid. The alkali metal algin compound is soluble in water.

Alginic acid, a natural substance obtained from brown algae or certain bacteria, is a polyuronic acid composed of two uronic acids linked together by 1,4-glycoside bonds: β-D acid (M) and acid glucuronic α-L (G)

Alginic acid is able to form water-soluble salts (alginates) with alkali metals such as sodium, potassium or lithium. These alginates are soluble in water in aqueous medium at pH 4, but dissociate into alginic acid at pH below 4.

Methods for recovering such water-soluble salts, especially sodium alginate, from natural sources are well known and are described, for example, in Green, U.S. Patent No. 2,036,934, and Le Gloahec, U.S. Patent No. 2,128,551.

Alginic acid or alginates can be modified chemically, in particular with urea or urethane groups or by reactions of hydrolysis, oxidation, esterification, etherification, sulphation, phosphation, amination, d amidation or alkylation, or by several of these modifications, forming derivatives of alginic acid, including salts.

These derivatives can be anionic, cationic, amphoteric or nonionic and can form water-soluble salts with an alkali metal such as sodium, potassium or lithium, forming alkali metal salts of alginic acid derivatives.

Specifically, alginates can be reacted with an alkylene oxide, such as ethylene oxide or propylene oxide, to form polyglycol alginates. The polyglycol segment is linked to alginates through the carboxyl group(s). In general, alginates react with propylene oxide to form polypropylene glycol alginates (PPG alginates), while they react with ethylene oxide to form polyethylene glycol alginates (PEG alginates). Preferably, the polyglycol alginate has a degree of esterification of about 40% to about 95%, preferably about 70% to 95%.

Suitable alginates have an average molecular weight of about 20,000 daltons to about 500,000 daltons. The average molecular weight is calculated by first determining the intrinsic viscosity and then using the Mark-Houwink Sakurada equation, as in Martinsen, et al, "Comparison of Different Methods for Determining Molecular Weights and Weight Distribution molecular weight of alginates” (Carbohydre. Polym., 15, 171-193, 1991).

The average molecular weights given above are also valid for the alkali metal salts of alginic acid derivatives.

A listing of the various commercially available alginates, their properties and sources can be found in Shapiro, U.S. Patent No. 6,334,968, Table 1, column 16, line 49, through column 17, line 18.

According to one embodiment of the present invention, the alkali metal algin compound can be selected from sodium alginate and potassium alginate, preferably sodium alginate.

The alginic compounds of alkali metals which can be used in the present invention can be represented, for example, by the products sold under the names of Kelcosol, Satialgine™, Cecalgum™ or Algogel™ by the company Cargill Products, under the name Protanal™ by the company FMC Biopolymère, under the name Grindsted® Alginate by the company Danisco, under the name Kimica Algin by the company Kimica, and under the names Manucol® and Manugel® by the company ISP.

According to one embodiment of the present invention, the aqueous composition comprises at least one water-soluble gelatinizing agent, which is gelatinizable with the gel-forming agent and produces a water-insoluble polyvalent metal salt.

According to one embodiment of the present invention, the aqueous composition comprising at least one water-soluble gelatinizing agent is a saline solution of calcium, a saline solution of strontium, a saline solution of zinc, a saline solution of copper, a manganese salt solution, with an acid, wherein the acid is preferably selected from sulfuric acid and hydrochloric acid, or a mixture of these, preferably calcium chloride, calcium sulphate , calcium sulphate or a mixture thereof.

More specifically, the water-insoluble salt of the polyvalent metal can be an alginate, preferably selected from calcium alginate, strontium alginate, zinc alginate, copper alginate, alginate manganese or a mixture of these, preferably calcium or copper alginate, in particular calcium alginate.

The term “alginate” designates in particular a salt of alginic acid. Alginic acid, a natural substance obtained from brown algae or certain bacteria, is a polyuronic acid composed of two uronic acids linked together by 1,4-glycoside bonds: β-D acid (M) and acid α-L glucuronic acid (G).

Water-insoluble alginates, in which the main cation is calcium, are found specifically in the fronds and stems of algae of the class Phaeophyceae , examples of which are Fucus vesiculosus, Fucus spiralis , Ascophyllum nodosum , Macrocystis pyrifera, Alaria esculenta, Eclonia maxima, Lessonia nigrescens, Lessonia trabeculata, Laminaria japonica, Durvillea antarctica, Laminaria hyperborea, Laminaria longicruris, Laminaria digitata, Laminaria saccharina, Laminaria cloustoni and Saragassum sp.

Suitable non-water soluble alginates have an average molecular weight of about 20,000 daltons to about 500,000 daltons. The average molecular weight is calculated by first determining the intrinsic viscosity and then using the Mark-Houwink Sakurada equation, as in Martinsen, et al, "Comparison of Different Methods for Determining Molecular Weights and Weight Distribution molecular des alginates (Comparison of Different Methods for Determination of Molecular Weights and Molecular Weight Distribution of Alginates)” (Carbohydre. Polym., 15, 171-193, 1991).

The gel substrate can be prepared by following these steps:

- (1) provide a water-insoluble substrate and

- (2) mixing 1) the water-insoluble substrate and 2) the aqueous composition comprising at least one water-soluble gelatinizing agent to form a gel substrate,

- (3) dry the gel substrate.

Aqueous composition

According to one embodiment of the present invention, the aqueous composition is a composition which is capable of forming an emulsion with the oil powder. For example, according to one embodiment of the present invention, the aqueous composition comprises cosmetically and pharmaceutically acceptable water, such as demineralized water, optionally comprising functional agents which do not deteriorate the properties of the mask.

In the aqueous composition, there are few surfactants or emulsifiers, even no surfactants or emulsifiers. Therefore, the kit can offer skin comfort thanks to a reduction, or even the absence, of surfactant in the aqueous composition.

The water which is suitable for the invention can be floral water such as corn flower water and/or mineral water such as Vittel water, Lucas water or La Roche water. Posay and/or spring water.

The aqueous composition can also comprise organic solvents that are miscible in water (at room temperature: 25°C), for example monoalcohols containing 2 to 6 carbon atoms, such as ethanol or isopropanol; polyols, containing in particular from 2 to 20 carbon atoms, preferably containing from 2 to 10 carbon atoms and preferably containing from 2 to 6 carbon atoms, such as glycerol, propylene glycol, butylene glycol, pentylene glycol, hexylene glycol, dipropylene glycol or diethylene glycol; glycol ethers (in particular containing from 3 to 16 carbon atoms) such as mono-, di- or tripropylene glycol (C1-C4), mono-, di- or triethylene glycol (C1-C4) alkyl ethers and mixtures thereof .

The addition of polyols can improve the dissolving speed, distributing ability and stability of the oil powder, in which the polyol preferably has low density, high spreading ability, disperses the oil powder well. oil and accelerates the dissolution of the oil powder in the juice part.

According to one embodiment of the present invention, the polyols are in an amount of between 1% and 20% by weight, preferably between 2% and 15% by weight, or between 3% and 10% by weight, with respect to relates to the total weight of the aqueous compounds.

The aqueous composition can also comprise any water-soluble or water-dispersible compound compatible with an aqueous composition, such as gelling agents, film-forming polymers, thickeners or preservatives, and mixtures thereof.

The aqueous composition may also include a viscosity-increasing agent ("thickener" or "rheology-enhancing agent") for improved stability and a carrier emulsifier. Representative viscosity increasing agents include thickening agents and gelling agents. Viscosity increasing agents which may be useful in practicing the embodiments of the disclosure include those conventionally used in cosmetics and pharmaceuticals. Viscosity increasing agents can be selected from, for example, vegetable gums, salts, acrylate viscosity increasing agents and mixtures thereof.

Active Agents

According to one embodiment of the present invention, the kit or the products of the present invention may comprise at least one functional agent, such as at least one active agent, for example, chosen from: stripping or moisturizing agents; depigmentation or anti-depigmentation agents; anti-glycation agents; anti-NO agents; agents for stimulating the synthesis of dermal or epidermal macromolecules and/or for preventing their degradation; agents stimulating the proliferation of fibroblasts or keratinocytes and/or the differentiation of keratinocytes; muscle relaxants or dermo-decontracting agents; free radical scavengers or antipollution agents; tensile agents; agents acting on capillary circulation; certainly the following particularly active agents and mixtures thereof:

Among all the active agents which can be used in the present invention, mention may be made in particular of: α - or β-hydroxy acids such as lactic acid, glycolic acid, citric acid, 5- octanoylsalicyclic, α-hydroxydecanoic acid, α-hydroxylauric acid, tartaric acid, glucuronic acid, galacturonic acid, acrylic acid, α-hydroxybutyric acid, α-hydroxyisobutyric acid, malic acid, mandelic acid, phosphoric acid, pyruvic acid, lactobionic acid and salicylic acid.

It is also possible to use anti-acne agents, such as salicylic acid or benzoyl peroxide, octopirox, dextrorotatory and levorotatory sulfur-containing amino acids, their salts and their N-acetyl derivatives such as N-acetylcysteine, or agents aimed at preventing aging of the skin and/or improving its condition, for example, the aforementioned α- and β-hydroxy acids, retinoids such as retinoic acid, retinol and its esters , such as, for example, retinyl propionate and retinyl acetate, or retinyl palmitate, niacinamide, allantoin, aloe extracts, azelaic acid, bisabolol, phytic acid, collagen or agents stimulating the formation of collagen, vitamins such as vitamin C or its derivatives such as ascorbyl glucoside, vitamin E or its derivatives, vitamin A or its derivatives, vitamin F or its derivatives, acids dextrorotatory and levorotatory sulphur-containing amines and their derivatives és as mentioned above, elastin, N-acetyl-D-glucosamine, luteolin or antioxidants such as green tea or active fractions thereof, glycerin, laponite, caffeine, oils essential aromatics, coloring agents, free radical scavengers, moisturizing agents, depigmentation agents, agents for improving the color of the skin such as artificial tanning agents of the dihydroxyacetone or tyrosine ester type, liporegulators, softeners, anti-wrinkle agents, keratolytic agents, fresheners, deodorants, anesthetics, nourishing agents and mixtures of these agents. It is also possible to use bleaching agents such as kojic acid, ascorbyl phosphates, ascorbyl glucosides, ascorbic acid and mixtures thereof.

It is also possible to use active agents to improve the condition of the skin in the case of a mask, such as moisturizers or agents serving to improve the natural lipid barrier, such as ceramides, cholesterol sulphates and/or fatty acids, and mixtures thereof. It is also possible to use enzymes which have an activity on the skin, such as proteases, lipases, cerebrosidases and/or melanases, and mixtures thereof.

Other examples of active agents which can be adapted to the implementation of the present invention, in particular agents for drugs, peptides, proteins, detectable labels, contrast reagents, analgesics, anesthetics, antibacterial agents, anti-yeast agents, antifungal agents, antiviral agents, anti-dermatitis agents, anti-pruritic agents, anti-emetics, vascular protectors, anti-motion sickness agents, anti-irritants, anti-inflammatories, immunomodulators, anti-hyperkeratolytic agents, agents for treating dry skin, antiperspirants, anti-psoriatic agents, anti-dandruff agents, anti-aging agents, anti-asthmatic agents and bronchodilators, sun protection agents, antihistamines, healing agents, corticosteroids, tanning agents and mixtures thereof.

The content of at least one active agent in the first composition and/or in the second composition can be adjusted according to the objective targeted by the kit.

Additives

In a known manner, the kit of the present invention may also contain adjuvants common in cosmetics and/or dermatology, such as preservatives, antioxidants, pH modifiers (acid or base), perfumes, fillers, bactericides, odor absorbers, dyes (pigments and dyes), emulsifiers, as well as lipid vesicles.

It goes without saying that a person skilled in the art will take care to select this or these optional additional compounds, and/or their quantity, so that the advantages of the second composition according to the present invention are not, or are not substantially , adversely affected by the proposed addition.

Method and use

The mask or a dressing for a skin lesion according to the present invention can be prepared according to the following steps:

- (1) providing the substrate as defined in the present invention;

- (2) providing the oil powder(s) as defined in the present invention;

- (3) providing the additional hydrophilic and/or lipophilic powder(s) as defined in the present invention;

and

- (4) mixing 1) the oil powder(s) and the additional hydrophilic and/or lipophilic powder, and 2) the aqueous composition, optionally with a physical massage (e.g. manual massage), to form an emulsion at room temperature and

wherein the emulsion obtained impregnates the substrate to form a mask or a dressing for skin lesions.

With this kit, two parts are separated: (1) dry part — (first kit (including substrate and oil powder(s)) with additional hydrophilic and/or lipophilic powder(s)( s) and (2) wet end — (second kit (including aqueous composition)), this kit allows easy impregnation of the substrate and filling, compared to the normal emulsification phase.

Since the present kit has two parts (dry part and wet part) separated, just before use, the two parts are mixed and processed to be a mask with emulsion, which has better stability tendency and higher hydration and greater feeling of nutritious touch.

Thanks to the combination of the present oil powder and the additional hydrophilic and/or lipophilic powder, the present present kit offers a faster dissolution rate and a better rate of dispersion of the present oil powder(s). invention, even over other oil powders or without the present additional hydrophilic and/or lipophilic powder.

According to one embodiment, the kit according to the present invention can also be used to treat the skin lesion, to prevent post-surgical adhesion formation or to fill or repair osteochondrial defects, etc. This use may manifest as a process for treating skin lesions, preventing post-surgical adhesion formation, or filling or repairing osteochondrial defects, including the application of this Mask or the Skin Lesion Dressing of the present invention to a location that needs it.

In order to store the two-phase composition according to the present invention, before the anhydrous part and the water-based part, the anhydrous part and the water-based part are separated from each other in two separate containers or preferably in one container. When a single container is used, the water portion may be packaged in the body of a closed container with a lid containing the anhydrous portion, a puncturable and/or detachable separator being provided between the anhydrous portion and the water portion. Such packages include those described in FR-A-2,476,607, FA-A-2,453,793 or FR-A-2,645,740, all incorporated by reference herein.

Although the numerical ranges and parameters which define the broad scope of the present invention are approximations, the numerical values stated in the specific examples are reported as accurately as possible. However, any numerical value inherently contains certain errors necessarily resulting from the standard deviation found in their respective measurements. The following examples are intended to illustrate the present invention without however limiting its scope.

EXAMPLES

The amounts/concentrations of ingredients in the compositions/formulas described below are expressed in parts by weight.

Example 1:

1. Kit preparation

The kit was prepared according to the following standard procedure.

1. Substrate

A nonwoven fabric was used as the water-insoluble substrate.

2. Oil powders

Oil powder (i.e. MILK TEA POWDER) (Trade Name: Vegetable Fat Powder, Akofine R; Supplier: AARHUSKARLSHAMN) was used in the Examples.

The fatty acid residues used in the composition of the oil of the Examples are as follows. Palmitic acid (C16:0) 4% by weight Stearic acid (C18:0) 40% by weight Arachidic acid (C20:0) 10% by weight Behenic acid (C22:0) 44% by weight Lignoceric acid (C24:0) 1% by weight

3. Additional hydrophilic and/or lipophilic powders

Silica (available from AGC si-tech with the product SUNSPHERE H 51) was used in the Examples.

4. Aqueous composition

Purified water was used as the aqueous composition.

1. Preparing the mask

Package (1) included Package (1a) with the oil powder, and additional hydrophilic and/or lipophilic powders (if any) and Package (1b) the substrate, as the dry part. The package (2) included the juice comprising the aqueous composition, optionally composed of oil powder, as the wet part (called the juice part).

Package (1a) contained the oil powder and additional hydrophilic and/or lipophilic powders, and/or Package (1b) the substrate were mixed with the juice from Package (2) comprising the aqueous composition (optionally consisting of oil powder), under manual massage for 1 min at room temperature to form an emulsion, the substrate obtained above was impregnated with the emulsion obtained to form a mask.

The juice was next.

No. Sample 01 Sample 02 Sample 03 Sample 04 Sample 05 Original Total
%(P/P) Total
%(P/P) Total
%(P/P) Total
%(P/P) Total
%(P/P) PURIFIED WATER 51.15 48.15 48.15 47.15 51.15 sodium citrate 0.30 0.30 0.30 0.30 0.30 HYDROXYACETOPHENONE 0.50 0.50 0.50 0.50 0.50 Glycereth-26 0.80 0.80 0.80 0.80 0.80 PURIFIED WATER 5.00 5.00 5.00 5.00 5.00 Sodium hyaluronate 0.05 0.05 0.05 0.05 0.05 DIPOTASSIUM GLYCYRRHIZATE 0.10 0.10 0.10 0.10 0.10 Glycerine 6.50 6.50 6.50 6.50 6.50 MILK TEA powder - 3.00 - - - Dicaprylic carbonate - - 3.00 3.00 - Polysorbate 60 - - - 0.50 - Sorbitan sesquioleate - - - 0.50 - Propanediol 4.00 4.00 4.00 4.00 4.00 xanthan gum 0.10 0.10 0.10 0.10 0.10 Hydroxyethylcellulose 0.10 0.10 0.10 0.10 0.10 Water 30.00 30.00 30.00 30.00 30.00 ACRYLATES/C10-30 ALKYL ACRYLATE CROSS LINKED POLYMER 0.30 0.30 0.30 0.30 0.30 Tromethamine 0.09 0.09 0.09 0.09 0.09 CAPRYLIC/Capric GLUCOSIDE 1.00 1.00 1.00 1.00 1.00 CITRIC ACID 0.01 0.01 0.01 0.01 0.01

1. Evaluation of the Invention and Comparative Masks or Skin Lesion Dressing

1. Emulsion evaluation

The transformation of the emulsified juice from Package (1a) to the oil powder, and additional hydrophilic and/or lipophilic powders and/or substrate from Package (1b) as above, mixed with Package (2) was measured. ) juice comprising the aqueous composition (optionally comprising the oil powder), under manual massage for 1 min at room temperature.

The results of the kit and its processing properties (to form the emulsion) are given in Table 2. In Table 2, the component content is expressed in parts by weight.

Formula number Sample 01 Sample 02 Sample 03 Sample 04 Sample 05 Design difference MILK TEA POWDER (i.e. Oil POWDER) 3% dry part OIL POWDER 3% Liquid OIL (dicaprylic carbonate) 3% OIL (dicaprylic carbonate) 3% + surfactant (polysorbate 60 0.5%/sorbitane sequioleate 0.5%) 3% Oil POWDER + silica in dry part Transform into emulsified juice Possible Impossible Impossible Impossible
(juice already emulsified) Possible

- In the case of Sample 01, the juice from Package (2) is the wet part and the 3% MILK TEA powder is added to the substrate. This kit had two packages: Package (1a) with the oil powder and (1b) the substrate and Package (2) with the juice.

- In the case of Sample 02, the juice (Sample 02) was composed of 3% MILK TEA powder added to the substrate. This kit had two packages: Package (1b) with the substrate and Package (2) with the juice including the oil powder. This kit showed lower stability than Sample 01. Sample 02 had the same components as Sample 01.

- In the case of Sample 03, this kit did not include the oil powder and the additional hydrophilic and/or lipophilic powders of the present invention, but only 3% oil in the juice without emulsifier. This kit included one package: Package (1b) substrate with (2) juice including oil without emulsifier. This kit showed juice instability.

- In the case of Sample 04, this kit did not include the oil powder and the additional hydrophilic and/or lipophilic powders of the present invention, but only 3% oil in the juice without emulsifier. This kit included one package: Package (1b) of the substrate with (2) juices including the oil with emulsifier. This kit showed that there was no emulsion formation.

- In the case of Sample 05, this sample is the same as that of Sample 01, except that there are additional hydrophilic and/or lipophilic powders, i. e. silica.

Conclusion

The mask of the present invention is superior in terms of beneficial properties, eg superior processing properties (to form the emulsion). In conclusion, Samples 01 and 05 with separate packets gave the most stable stability results and the best emulsified juice processing property.

Example 2: Evaluation of the stability and dissolution rate of oil powder

1. Oil powder used

The oil powder was prepared as follows. Sodium Starch Octenylsuccinate 25.9% Glycerylstearate citrate 0.46% Glyceryl Monostearate 0.78% Sodium stearoyl lactylate 0.06 Canola oil 29.2% Butyrospermum parkii butter 5.1% Maltodextrin 38.5%

Protocol:

There are two types of samples: (1) oil powder only; (2) oil powder mixed with silica at 2% by weight (Available from AGC si-tech under the name SUNSPHERE H 51).

These samples were baked, and their appearances, dissolution conditions, and sensory sensations were recorded (1) at the start of baking, under T0; (2) during cooking, under T1, T2 and T3.

Results:

The results are given in the following tables.

[TABLE 3]

(1) during cooking, T1: 2 weeks Oil powder only Oil powder + silica 2% by weight Aspect Changes and becomes more yellow than T0 Same as T0 Effect of cooking Start cooking within one week in chamber at 45℃, with 80% humidity No baking in chamber at 45℃, with 80% humidity Condition of dissolution 1 min (slower than T0) 21.65s (same as T0) Sensory sensation Same as T0 Same as T0

[TABLE 4]

(2) during cooking, at T2: 1 month Oil powder only Oil powder + silica 2% by weight Aspect Changes and becomes more yellow than T0
Tangled Same as T0 Effect of cooking Start cooking within one week in chamber at 45℃, with 80% humidity No baking in chamber at 45℃, with 80% humidity Condition of dissolution More than 2 min (slower than T1) 28.34s (Same as T0) Sensory sensation Same as T0 Same as T0

[TABLE 5]

(3) during cooking, at T3:2 months Oil powder only Oil powder + silica 2% by weight Aspect Changes and becomes more yellow than T0
Tangled Same as T0 Effect of cooking Start cooking within one week in chamber at 45℃, with 80% humidity No baking in chamber at 45℃, with 80% humidity Condition of dissolution More than 2 min and undissolved particles persist 30.33s (Same as T0) Sensory sensation Same as T0 Same as T0

Conclusion

As for the powdered oil sample only, it gave the same stability results as the lab scale sample, i.e. it was tangled and the color changed. On the other hand, other samples with 2 wt% silica showed stable results and the dissolution rate was almost the same as T0. In conclusion, adding additional hydrophilic and/or lipophilic powders can reduce oil powder tangling and improve oil powder stability.

The term "comprising" (and its grammatical variations) used in this document is used in the inclusive sense of "having" or "including" and not in the exclusive sense of "comprising only".

The foregoing description illustrates and describes the present disclosure. Further, the disclosure only shows and describes preferred embodiments of the disclosure, but, as mentioned above, is understood to be capable of changes or modifications in scope of concept such as expressed herein, to the extent of the teachings and/or skill or knowledge of the relevant art. The provisions described above are further intended to explain the more well-known modes of practicing the disclosure and to enable others skilled in the art to use the disclosure in such or other embodiments and with the various modifications required by the particular applications or uses disclosed herein. Accordingly, the description is not intended to limit the disclosure to the form disclosed herein. It is also understood that the appended claims are to be construed to include alternative embodiments.

Claims (10)

A kit including:
1) A first kit composition comprising
- at least one substrate,
- at least one oil powder capable of forming an emulsion with an aqueous composition,
- at least one additional hydrophilic and/or lipophilic powder,
2) A second kit composition comprising at least one aqueous composition capable of forming an emulsion with the oil powder,
where the first kit composition and the second kit composition are placed separately from each other. A kit according to claim 1, wherein the additional hydrophilic and/or lipophilic powder is selected from silica, cellulose-based compound, nylon or a mixture thereof. Kit according to claim 1, wherein the part of the substrate and another part of the oil powder(s) as well as the additional hydrophilic and/or lipophilic powder in the first composition of the kit are placed separately from each other . Kit according to claim 1 or 2, in which at least one oil powder comprises:
- oil composition(s), consisting largely of a mixture of mono-, di- and triglycerides, and a mixture of the latter, optionally containing all the constituent fatty acids;
- one or more emulsifier(s), whose HLB value is preferably equal to or greater than 7, preferably from 7 to 20, and in particular from 11 to 16;
- optionally bases forming the powder;
- optionally, binder(s) or diluent(s),
- possibly, stabilizers. A kit according to claim 4, wherein the emulsifier used in the oil powder(s) has an HLB value of 7 or more, preferably 7 to 20, especially 11 to 16, e.g. fatty acid esters polyglycerin, fatty acid esters of sorbitan, fatty acid esters of polyoxyethylene sorbitan, fatty acid esters of propylene glycol, fatty acid esters of sucrose, lecithin, lecithins such as enzymatically decomposed lecitins, esters of acid of mono fatty acids of glycerin and esters of organic acids of monoglycerides such as acetylated monoglyceride, lactylated monoglyceride, citrated monoglyceride and mixtures thereof. Kit according to Claim 4, in which the binder used in the oil powder is selected from at least one polymer, such as maltodextrin, at least one fat-based material, and mixtures thereof, the sugars such as xylitol, trehalose, and its mixture. Kit according to one of the preceding claims, in which the powdered oil additionally comprises surfactants chosen from anionic or cationic surfactants, for example glyceryl monostearate, sodium stearoyl lactylate and its mixture. Kit according to any of the preceding claims, wherein the emulsifier(s) and/or the surfactant(s) are only included in the oil powder(s). Kit according to one of the preceding claims, in which the additional hydrophilic and/or lipophilic powder is coated on the oil powder(s). Kit according to one of the preceding claims, in which the second kit composition additionally comprises at least one polyol.