FR3080278B1 - Procede de fabrication d'un spheroide de cannabidiol - Google Patents
Procede de fabrication d'un spheroide de cannabidiol Download PDFInfo
- Publication number
- FR3080278B1 FR3080278B1 FR1853165A FR1853165A FR3080278B1 FR 3080278 B1 FR3080278 B1 FR 3080278B1 FR 1853165 A FR1853165 A FR 1853165A FR 1853165 A FR1853165 A FR 1853165A FR 3080278 B1 FR3080278 B1 FR 3080278B1
- Authority
- FR
- France
- Prior art keywords
- cannabidiol
- active
- manufacturing
- active principle
- spheroid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- QHMBSVQNZZTUGM-UHFFFAOYSA-N Trans-Cannabidiol Natural products OC1=CC(CCCCC)=CC(O)=C1C1C(C(C)=C)CCC(C)=C1 QHMBSVQNZZTUGM-UHFFFAOYSA-N 0.000 title abstract 5
- QHMBSVQNZZTUGM-ZWKOTPCHSA-N cannabidiol Chemical compound OC1=CC(CCCCC)=CC(O)=C1[C@H]1[C@H](C(C)=C)CCC(C)=C1 QHMBSVQNZZTUGM-ZWKOTPCHSA-N 0.000 title abstract 5
- 229950011318 cannabidiol Drugs 0.000 title abstract 5
- ZTGXAWYVTLUPDT-UHFFFAOYSA-N cannabidiol Natural products OC1=CC(CCCCC)=CC(O)=C1C1C(C(C)=C)CC=C(C)C1 ZTGXAWYVTLUPDT-UHFFFAOYSA-N 0.000 title abstract 5
- PCXRACLQFPRCBB-ZWKOTPCHSA-N dihydrocannabidiol Natural products OC1=CC(CCCCC)=CC(O)=C1[C@H]1[C@H](C(C)C)CCC(C)=C1 PCXRACLQFPRCBB-ZWKOTPCHSA-N 0.000 title abstract 5
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 241001441724 Tetraodontidae Species 0.000 title 1
- 241000196324 Embryophyta Species 0.000 abstract 3
- 235000012438 extruded product Nutrition 0.000 abstract 2
- 239000002243 precursor Substances 0.000 abstract 2
- 244000025254 Cannabis sativa Species 0.000 abstract 1
- 235000008697 Cannabis sativa Nutrition 0.000 abstract 1
- 239000002250 absorbent Substances 0.000 abstract 1
- 230000002745 absorbent Effects 0.000 abstract 1
- 239000003463 adsorbent Substances 0.000 abstract 1
- 230000001747 exhibiting effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229920003023 plastic Polymers 0.000 abstract 1
- 239000004033 plastic Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Procédé de fabrication d'un sphéroïde comprenant du cannabidiol dans lequel : a) On mélange un principe actif isolé, une solution active d'origine végétale contenant ledit principe actif ou un précurseur de celui-ci, avec une substance absorbante et adsorbante présentant des propriétés plastiques, b) on extrude ledit mélange jusqu'à obtention d'un produit extrudé, c) on sphéronise ledit produit extrudé jusqu'à obtention d'un sphéroïde, caractérisé en ce que ledit principe actif isolé consiste en du cannabidiol et en ce que ladite solution active d'origine végétale consiste en un extrait actif, issu d'un végétal du genre Cannabis sativa L, contenant du cannabidiol et/ou un précurseur de cannabidiol.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1853165A FR3080278B1 (fr) | 2018-04-11 | 2018-04-11 | Procede de fabrication d'un spheroide de cannabidiol |
| PCT/IB2019/052937 WO2019198001A1 (fr) | 2018-04-11 | 2019-04-10 | Procede de fabrication d'un spheroide comprenant du cannabidiol |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1853165 | 2018-04-11 | ||
| FR1853165A FR3080278B1 (fr) | 2018-04-11 | 2018-04-11 | Procede de fabrication d'un spheroide de cannabidiol |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR3080278A1 FR3080278A1 (fr) | 2019-10-25 |
| FR3080278B1 true FR3080278B1 (fr) | 2021-04-30 |
Family
ID=66476677
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR1853165A Active FR3080278B1 (fr) | 2018-04-11 | 2018-04-11 | Procede de fabrication d'un spheroide de cannabidiol |
Country Status (2)
| Country | Link |
|---|---|
| FR (1) | FR3080278B1 (fr) |
| WO (1) | WO2019198001A1 (fr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021226725A1 (fr) * | 2020-05-15 | 2021-11-18 | Hexo Operations Inc. | Haschich présentant des caractéristiques sensiblement uniformes et son procédé de production à une échelle industrielle |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA77145C2 (en) * | 1997-11-05 | 2006-11-15 | Wyeth Corp | Extended release dosage formulation |
| FR2794346B1 (fr) * | 1999-06-02 | 2004-08-06 | Ile D Inventeurs Apis Spheromo | Formulation et procede de production de spheroides a partir d'une boisson fermentee ou d'un jus fermente par exemple du vin |
| RS53624B1 (en) * | 2006-03-16 | 2015-04-30 | Euro-Celtique S.A. | PHARMACEUTICAL SFEROIDS |
| WO2008021394A2 (fr) * | 2006-08-15 | 2008-02-21 | Theraquest Biosciences, Llc | Formulations pharmaceutiques d'agonistes cannabinoïdes et procédé d'utilisation |
-
2018
- 2018-04-11 FR FR1853165A patent/FR3080278B1/fr active Active
-
2019
- 2019-04-10 WO PCT/IB2019/052937 patent/WO2019198001A1/fr active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| WO2019198001A1 (fr) | 2019-10-17 |
| FR3080278A1 (fr) | 2019-10-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PLFP | Fee payment |
Year of fee payment: 2 |
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| PLSC | Publication of the preliminary search report |
Effective date: 20200228 |
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| PLFP | Fee payment |
Year of fee payment: 3 |
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| PLFP | Fee payment |
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| PLFP | Fee payment |
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