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FR2819512B1 - NOVEL CYCLO [D] AZEPANE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM - Google Patents

NOVEL CYCLO [D] AZEPANE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Info

Publication number
FR2819512B1
FR2819512B1 FR0100639A FR0100639A FR2819512B1 FR 2819512 B1 FR2819512 B1 FR 2819512B1 FR 0100639 A FR0100639 A FR 0100639A FR 0100639 A FR0100639 A FR 0100639A FR 2819512 B1 FR2819512 B1 FR 2819512B1
Authority
FR
France
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
azepane
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0100639A
Other languages
French (fr)
Other versions
FR2819512A1 (en
Inventor
Patrick Casara
Diguarher Thierry Le
Gilbert Dorey
John Hickman
Alain Pierre
Gordon Tucker
Nicolas Guilbaud
Jean Luc Fauchere
Jean Claude Ortuno
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Servier SAS
Original Assignee
Laboratoires Servier SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Servier SAS filed Critical Laboratoires Servier SAS
Priority to FR0100639A priority Critical patent/FR2819512B1/en
Priority to PCT/FR2002/000149 priority patent/WO2002057258A1/en
Priority to ARP020100172A priority patent/AR034288A1/en
Publication of FR2819512A1 publication Critical patent/FR2819512A1/en
Application granted granted Critical
Publication of FR2819512B1 publication Critical patent/FR2819512B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR0100639A 2001-01-18 2001-01-18 NOVEL CYCLO [D] AZEPANE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Expired - Fee Related FR2819512B1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
FR0100639A FR2819512B1 (en) 2001-01-18 2001-01-18 NOVEL CYCLO [D] AZEPANE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
PCT/FR2002/000149 WO2002057258A1 (en) 2001-01-18 2002-01-16 Cyclo`d!azepane derivatives which are used as farnesyltransferase inhibitors and method for the preparation thereof
ARP020100172A AR034288A1 (en) 2001-01-18 2002-01-18 CYCLE COMPOUNDS [D] AZEPAN, PROCEDURE FOR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0100639A FR2819512B1 (en) 2001-01-18 2001-01-18 NOVEL CYCLO [D] AZEPANE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Publications (2)

Publication Number Publication Date
FR2819512A1 FR2819512A1 (en) 2002-07-19
FR2819512B1 true FR2819512B1 (en) 2003-02-21

Family

ID=8858953

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0100639A Expired - Fee Related FR2819512B1 (en) 2001-01-18 2001-01-18 NOVEL CYCLO [D] AZEPANE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Country Status (3)

Country Link
AR (1) AR034288A1 (en)
FR (1) FR2819512B1 (en)
WO (1) WO2002057258A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2004024141A1 (en) * 2002-08-29 2006-01-05 協和醗酵工業株式会社 Hsp90 family protein inhibitors
KR100765027B1 (en) 2002-12-20 2007-10-09 글락소 그룹 리미티드 Benzazepine Derivatives for the Treatment of Neurological Disorders
DE102004006325A1 (en) * 2004-02-10 2005-08-25 Bayer Healthcare Ag New benzazepine derivatives useful for treating or preventing dyslipidemia, arteriosclerosis, restenosis and ischemia

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994026723A2 (en) * 1993-05-14 1994-11-24 Genentech, Inc. ras FARNESYL TRANSFERASE INHIBITORS
IL117580A0 (en) * 1995-03-29 1996-07-23 Merck & Co Inc Inhibitors of farnesyl-protein transferase and pharmaceutical compositions containing them
JP2000508631A (en) * 1996-04-03 2000-07-11 メルク エンド カンパニー インコーポレーテッド Inhibitors of farnesyl protein transferase
CA2249601A1 (en) * 1996-04-03 1997-10-23 Thorsten E. Fisher Inhibitors of farnesyl-protein transferase
TW527355B (en) * 1997-07-02 2003-04-11 Bristol Myers Squibb Co Inhibitors of farnesyl protein transferase
AU2477400A (en) * 1998-12-08 2000-06-26 Merck & Co., Inc. Inhibitors of prenyl-protein transferase

Also Published As

Publication number Publication date
FR2819512A1 (en) 2002-07-19
AR034288A1 (en) 2004-02-18
WO2002057258A1 (en) 2002-07-25

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Legal Events

Date Code Title Description
ST Notification of lapse