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FR2813791B1 - Utilisation de 2- et 4-quinolones pour inhiber la neo-proliferation intimale - Google Patents

Utilisation de 2- et 4-quinolones pour inhiber la neo-proliferation intimale

Info

Publication number
FR2813791B1
FR2813791B1 FR0011738A FR0011738A FR2813791B1 FR 2813791 B1 FR2813791 B1 FR 2813791B1 FR 0011738 A FR0011738 A FR 0011738A FR 0011738 A FR0011738 A FR 0011738A FR 2813791 B1 FR2813791 B1 FR 2813791B1
Authority
FR
France
Prior art keywords
quinolones
neo
proliferation
inhibit intimal
intimal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0011738A
Other languages
English (en)
Other versions
FR2813791A1 (fr
Inventor
Francis Darro
Benoit Joseph
Robert Kiss
Gerald Guillaumet
Armand Frydman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cephalon France SAS
Original Assignee
Laboratoire L Lafon SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoire L Lafon SA filed Critical Laboratoire L Lafon SA
Priority to FR0011738A priority Critical patent/FR2813791B1/fr
Priority to AU2001291947A priority patent/AU2001291947A1/en
Priority to PCT/FR2001/002849 priority patent/WO2002022074A2/fr
Publication of FR2813791A1 publication Critical patent/FR2813791A1/fr
Application granted granted Critical
Publication of FR2813791B1 publication Critical patent/FR2813791B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4704—2-Quinolinones, e.g. carbostyril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR0011738A 2000-09-14 2000-09-14 Utilisation de 2- et 4-quinolones pour inhiber la neo-proliferation intimale Expired - Fee Related FR2813791B1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
FR0011738A FR2813791B1 (fr) 2000-09-14 2000-09-14 Utilisation de 2- et 4-quinolones pour inhiber la neo-proliferation intimale
AU2001291947A AU2001291947A1 (en) 2000-09-14 2001-09-13 Use of 2- and 4- quinolones for inhibiting intimal neo-proliferation
PCT/FR2001/002849 WO2002022074A2 (fr) 2000-09-14 2001-09-13 Utilisation de 2- et 4-quinolones pour inhiber la neo-proliferation intimale

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0011738A FR2813791B1 (fr) 2000-09-14 2000-09-14 Utilisation de 2- et 4-quinolones pour inhiber la neo-proliferation intimale

Publications (2)

Publication Number Publication Date
FR2813791A1 FR2813791A1 (fr) 2002-03-15
FR2813791B1 true FR2813791B1 (fr) 2004-03-12

Family

ID=8854308

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0011738A Expired - Fee Related FR2813791B1 (fr) 2000-09-14 2000-09-14 Utilisation de 2- et 4-quinolones pour inhiber la neo-proliferation intimale

Country Status (3)

Country Link
AU (1) AU2001291947A1 (fr)
FR (1) FR2813791B1 (fr)
WO (1) WO2002022074A2 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2522670A1 (fr) 2004-04-07 2012-11-14 Takeda Pharmaceutical Company Limited Antagonistes hétérocycliques des récépteurs du CRF
WO2008017710A1 (fr) * 2006-08-10 2008-02-14 Ferrer Internacional S.A. Composés de 1h-quinolin-4-one, procédés, utilisations et compositions
EP1886996A1 (fr) * 2006-08-10 2008-02-13 Ferrer Internacional, S.A. Composés de1H-Quinolin-4-one, ayant une affinité pour le recepteur GABA, leurs procédés, leur utilisations et leurs compositions
TWI366565B (en) 2007-06-06 2012-06-21 Otsuka Pharma Co Ltd Quinolone compound and pharmaceutical composition
US20110251180A1 (en) 2008-12-05 2011-10-13 Otsuka Pharmaceutical Co., Ltd. Pharmaceutical agent comprising quinolone compound
TWI472525B (zh) 2008-12-05 2015-02-11 Otsuka Pharma Co Ltd 喹啉酮化合物及藥學組成物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5480883A (en) * 1991-05-10 1996-01-02 Rhone-Poulenc Rorer Pharmaceuticals Inc. Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase
SG64322A1 (en) * 1991-05-10 1999-04-27 Rhone Poulenc Rorer Int Bis mono and bicyclic aryl and heteroaryl compounds which inhibit egf and/or pdgf receptor tyrosine kinase
CA2079205C (fr) 1992-09-25 1998-02-10 Rudolf Edgar Falk Utilisation de l'acide hyaluronique et de formules pour empecher la restenose arterielle
US5834444A (en) 1991-07-03 1998-11-10 Hyal Pharmaceutical Corporation Hyaluronic acid and salts thereof inhibit arterial restenosis
WO1994002145A2 (fr) 1992-07-22 1994-02-03 Genelabs Technologies, Inc. 2-aryl-4-quinolones utilisees comme composes antitumoraux
GB9621757D0 (en) * 1996-10-18 1996-12-11 Ciba Geigy Ag Phenyl-substituted bicyclic heterocyclyl derivatives and their use
RU2209066C2 (ru) * 1997-06-02 2003-07-27 Янссен Фармацевтика Н.В. Производные (имидазол-5-ил)метил-2-хинолинона в качестве ингибиторов пролиферации клеток гладкой мышцы
PL343112A1 (en) * 1998-03-31 2001-07-30 Warner Lambert Co Quinolones as serine protease inhibitors
FR2781218B1 (fr) * 1998-07-15 2001-09-07 Lafon Labor Compositions pharmaceutiques comprenant des 2-quinolones

Also Published As

Publication number Publication date
WO2002022074A3 (fr) 2002-06-20
WO2002022074A2 (fr) 2002-03-21
AU2001291947A1 (en) 2002-03-26
FR2813791A1 (fr) 2002-03-15

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Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20070531