FR2869904B1 - Modulateurs des recepteurs lxr - Google Patents
Modulateurs des recepteurs lxrInfo
- Publication number
- FR2869904B1 FR2869904B1 FR0404958A FR0404958A FR2869904B1 FR 2869904 B1 FR2869904 B1 FR 2869904B1 FR 0404958 A FR0404958 A FR 0404958A FR 0404958 A FR0404958 A FR 0404958A FR 2869904 B1 FR2869904 B1 FR 2869904B1
- Authority
- FR
- France
- Prior art keywords
- lxr
- modulators
- receivers
- lxr receivers
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/58—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems with hetero atoms directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Child & Adolescent Psychology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0404958A FR2869904B1 (fr) | 2004-05-07 | 2004-05-07 | Modulateurs des recepteurs lxr |
CNA2005800146178A CN1950340A (zh) | 2004-05-07 | 2005-05-09 | Lxr受体调节剂 |
EP05769960A EP1742918A1 (fr) | 2004-05-07 | 2005-05-09 | Modulateurs des recepteurs lxr |
CA002564642A CA2564642A1 (fr) | 2004-05-07 | 2005-05-09 | Modulateurs des recepteurs lxr |
PCT/FR2005/001139 WO2005121093A1 (fr) | 2004-05-07 | 2005-05-09 | Modulateurs des recepteurs lxr |
AU2005251979A AU2005251979B2 (en) | 2004-05-07 | 2005-05-09 | LXR receptor modulators |
JP2007512270A JP4892475B2 (ja) | 2004-05-07 | 2005-05-09 | Lxr受容体モジュレーター |
CN2011102511968A CN102321020A (zh) | 2004-05-07 | 2005-05-09 | Lxr受体调节剂 |
US11/593,474 US7872021B2 (en) | 2004-05-07 | 2006-11-07 | LXR receptor modulators |
NO20065501A NO20065501L (no) | 2004-05-07 | 2006-11-29 | Lxr reseptor modulstorer. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0404958A FR2869904B1 (fr) | 2004-05-07 | 2004-05-07 | Modulateurs des recepteurs lxr |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2869904A1 FR2869904A1 (fr) | 2005-11-11 |
FR2869904B1 true FR2869904B1 (fr) | 2006-07-28 |
Family
ID=34945760
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR0404958A Expired - Fee Related FR2869904B1 (fr) | 2004-05-07 | 2004-05-07 | Modulateurs des recepteurs lxr |
Country Status (9)
Country | Link |
---|---|
US (1) | US7872021B2 (fr) |
EP (1) | EP1742918A1 (fr) |
JP (1) | JP4892475B2 (fr) |
CN (2) | CN1950340A (fr) |
AU (1) | AU2005251979B2 (fr) |
CA (1) | CA2564642A1 (fr) |
FR (1) | FR2869904B1 (fr) |
NO (1) | NO20065501L (fr) |
WO (1) | WO2005121093A1 (fr) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2886293B1 (fr) * | 2005-05-30 | 2007-08-24 | Fournier S A Sa Lab | Nouveaux composes de l'indoline |
GB0526257D0 (en) * | 2005-12-22 | 2006-02-01 | Novartis Ag | Organic compounds |
ES2393822T3 (es) * | 2007-08-13 | 2012-12-28 | F. Hoffmann-La Roche Ag | Nuevos derivados de piperazina-amida |
US8039493B2 (en) * | 2007-09-27 | 2011-10-18 | Hoffmann-La Roche Inc. | Biaryl sulfonamide derivatives |
CN103517908A (zh) | 2010-09-07 | 2014-01-15 | Seoul大学校产学协力财团 | 二倍半萜化合物及其用途 |
WO2017007755A1 (fr) | 2015-07-06 | 2017-01-12 | Rodin Therapeutics, Inc. | N-aminophényl-amides hétérocycliques en tant qu'inhibiteurs de l'histone désacétylase |
HUE057041T2 (hu) | 2015-07-06 | 2022-04-28 | Alkermes Inc | Hiszton deacetiláz hetero-halogén gátlói |
US11746097B2 (en) | 2016-06-24 | 2023-09-05 | Saint Louis University | LXR inverse agonists for treatment of cancer |
HRP20220223T1 (hr) | 2017-01-11 | 2022-04-29 | Alkermes, Inc. | Biciklički inhibitori histon deacetilaze |
EA039417B1 (ru) | 2017-08-07 | 2022-01-25 | Родин Терапеутикс, Инк. | Бициклические ингибиторы гистондеацетилазы |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2001517245A (ja) * | 1997-05-29 | 2001-10-02 | メルク エンド カンパニー インコーポレーテッド | 細胞接着阻害薬としてのビアリールアルカン酸類 |
BR9811569A (pt) * | 1997-07-31 | 2000-09-19 | Elan Pharm Inc | Compostos que inibem a adesão de leucócito mediada por vla-4 |
US6559127B1 (en) * | 1997-07-31 | 2003-05-06 | Athena Neurosciences, Inc. | Compounds which inhibit leukocyte adhesion mediated by VLA-4 |
AU751950B2 (en) * | 1997-11-24 | 2002-09-05 | Merck & Co., Inc. | Substituted beta-alanine derivatives as cell adhesion inhibitors |
US6251932B1 (en) * | 1998-09-25 | 2001-06-26 | Asta Medica Ag | Immunophilin ligands |
US6300341B1 (en) * | 1998-09-30 | 2001-10-09 | The Procter & Gamble Co. | 2-substituted heterocyclic sulfonamides |
US6316503B1 (en) * | 1999-03-15 | 2001-11-13 | Tularik Inc. | LXR modulators |
US6855708B2 (en) * | 2001-03-20 | 2005-02-15 | Merck & Co., Inc. | N-arylsulfonyl aza-bicyclic derivatives as potent cell adhesion inhibitors |
JP2005022976A (ja) * | 2001-07-18 | 2005-01-27 | Ajinomoto Co Inc | カルボン酸誘導体 |
TW200303742A (en) * | 2001-11-21 | 2003-09-16 | Novartis Ag | Organic compounds |
ATE453389T1 (de) | 2002-03-27 | 2010-01-15 | Smithkline Beecham Corp | Bestimmte pharmazeutisch wertvolle substituierte aminoalkyl-heterocyclen |
EP1487776A4 (fr) | 2002-03-27 | 2005-05-25 | Smithkline Beecham Corp | Composes acides et esters et procedes d'utilisation associes |
AU2003228614A1 (en) | 2002-04-23 | 2003-11-10 | Chugai Seiyaku Kabushiki Kaisha | Lxr modulators |
WO2003090746A1 (fr) | 2002-04-23 | 2003-11-06 | Chugai Seiyaku Kabushiki Kaisha | 1,3-thiazoles utilises en tant que modulateurs du lxr pour le traitement de maladies cardiovasculaires |
DE10229777A1 (de) | 2002-07-03 | 2004-01-29 | Bayer Ag | Indolin-Phenylsulfonamid-Derivate |
CA2567343A1 (fr) * | 2004-05-20 | 2005-12-01 | Elan Pharmaceuticals, Inc. | Inhibiteurs sulfonamido n-cycliques de gamma-secretase |
FR2886293B1 (fr) * | 2005-05-30 | 2007-08-24 | Fournier S A Sa Lab | Nouveaux composes de l'indoline |
-
2004
- 2004-05-07 FR FR0404958A patent/FR2869904B1/fr not_active Expired - Fee Related
-
2005
- 2005-05-09 WO PCT/FR2005/001139 patent/WO2005121093A1/fr not_active Application Discontinuation
- 2005-05-09 CA CA002564642A patent/CA2564642A1/fr not_active Abandoned
- 2005-05-09 EP EP05769960A patent/EP1742918A1/fr not_active Withdrawn
- 2005-05-09 AU AU2005251979A patent/AU2005251979B2/en not_active Ceased
- 2005-05-09 CN CNA2005800146178A patent/CN1950340A/zh active Pending
- 2005-05-09 CN CN2011102511968A patent/CN102321020A/zh active Pending
- 2005-05-09 JP JP2007512270A patent/JP4892475B2/ja not_active Expired - Fee Related
-
2006
- 2006-11-07 US US11/593,474 patent/US7872021B2/en not_active Expired - Fee Related
- 2006-11-29 NO NO20065501A patent/NO20065501L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CN102321020A (zh) | 2012-01-18 |
NO20065501L (no) | 2007-01-30 |
WO2005121093A1 (fr) | 2005-12-22 |
US20070099960A1 (en) | 2007-05-03 |
AU2005251979B2 (en) | 2012-04-12 |
FR2869904A1 (fr) | 2005-11-11 |
US7872021B2 (en) | 2011-01-18 |
EP1742918A1 (fr) | 2007-01-17 |
AU2005251979A1 (en) | 2005-12-22 |
JP4892475B2 (ja) | 2012-03-07 |
CA2564642A1 (fr) | 2005-12-22 |
CN1950340A (zh) | 2007-04-18 |
JP2007536355A (ja) | 2007-12-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |
Effective date: 20140131 |