FR2864426A1 - Food supplement designed to make up for nutritional deficiencies comprises paste matrix with added extracts of fruit, vegetable or animal origin, vitamins and minerals - Google Patents

Abstract

The food supplement consists of a paste matrix based on polymerised glucides giving it a solid or semi-solid jellified consistency, and one or more added ingredients that have a nutritional and/or physiological effect. The matrix can be based on fructo-oligosaccharides that give it a fibrous structure, and the added nutrients and/or ingredients are selected from extracts of vegetable, fruit, legume, plant and/or animal origin, vitamins, minerals, glucides, protides, lipids, macro-elements and/or oligoelements. Other ingredients in the basic formula include moisturising or diluting agents, emulsifiers, stabilisers or gelling agents, sweeteners, flavour enhancers, colourings and coatings. The product is designed to be made in chewable portions of 10 grams each.

Description

Food supplement to fill nutritional deficits

  The present invention relates to a dietary supplement to correct the nutritional deficiencies associated with many pathologies, and to reduce the risk factors for progression or complication of the pathology.

  Food supplements may be defined as foods intended to supplement the normal diet and as a concentrated source of nutrients or other substances with a nutritional and / or physiological effect. These supplements, which are generally marketed in the form of doses, namely, forms of presentation such as capsules, lozenges, tablets, pills and other similar forms, as well as sachets of powder, ampoules of liquid drop-filled vials and other similar forms of liquid or powder preparations intended to be taken in measured units of small quantity. Dietary supplements are available through various commercial sources, including health food stores, grocery stores, pharmacies etc. One of the first dietary supplements was in the form of a multi-vitamin tablet or capsule. and minerals, available in pharmacies. The most common food supplements include vitamins, minerals, nutrients or other substances with a nutritional or physiological effect of synthetic origin, or natural, animal, or plant.

  Dietary supplements are mainly used for weight loss (25%), well-being (45%) and beauty (25%). Due to regulatory restrictions, disease-related uses (prevention, treatment or cure) are not permitted, even though most products include elements with confirmed pharmacological activity.

  According to EU regulations, dietary supplements may include three categories of claims: nutritional, functional and relating to the reduction of a disease risk (health claim). It is therefore possible to refer to a general benefit, the preservation of good health, general well-being and a normal bodily function, to an improvement of a physiological function beyond what can be expected from diet alone, or the reduction of risk factors involved in the development of a disease.

  According to the current international regulation, food supplements may include plants, from one or more sources, because the plants are known for their phytotherapeutic activity. They may also include nutrients such as vitamins and / or minerals.

  The application EP 1 355 540 discloses a dietary supplement with a slimming effect, which strengthens the skeletal muscle and protects the cardiovascular system, the components of said complement being as follows Lcarnitine propionyl, coenzyme Qlo, nicotinamide, riboflavin and pantothenic acid.

  Patent FR 2,747,017 relates to a dietary supplement for ensuring and developing an optimal intake of natural substances needed by a body in good health, both in the skin and the body in general. The supplement described in this reference contains the following natural fruit and vegetable extracts: fig, bitter orange, lime, lime, carrot, parsley, celery, fennel, tomato, parsnip.

  The application WO 02 054 890 relates to a dietary supplement for maintaining and improving the health of the skin, comprising the following compounds: lycopene, carotenoids, biotin, chromium and selenium.

  The application US 2002 172 724 relates to a composition for reducing the risk of loss of bone density, including in particular a calcium compound and inulin, in a dietetically acceptable form.

  Organic diseases are usually accompanied by a metabolic deficiency. They are treated with specific medications and appropriate accompanying measures.

  Thus, pre-diabetic states and type II diabetes are treated with a variety of pharmacological agents to reduce blood sugar levels or insulin resistance. Metabolic therapies are used when significant abnormalities in blood glucose are detected and antiplatelet agents are commonly prescribed to delay an onset of the vascular complication of diabetes in the retina or retinopathy. Usually, a diet is also advised, but is not always well followed.

  Deficits in vitamins and minerals present in the prediabetic or diabetic subject are generally neither sought nor palliated by the medical prescription. The means to improve the general balance of the body and thus the well-being in the short and long term are also too often neglected. Yet, it is reported in the literature that a multitude of factors can contribute to the establishment of complications in diabetic states. Thus, several studies show that chromium supplementation can improve the control of circulating blood sugar (glycemia) in diabetics. A deficiency in magnesium interrupts insulin secretion by the pancreas and increases insulin resistance in body tissues, contributing to some diabetes complications. Zinc is known to protect the protein SPI, constitutive of the gene that codes for insulin, from oxidation. Thus, it exerts a protective action on insulin. Selenium, a potent antioxidant, also has an inhibitory effect on platelet aggregation, cells that play a role in the generation of vascular complications. Vitamin E helps to decrease diabetic retinopathy (defined above) and vitamin C is active in the prevention of retinopathy and cataracts.

  Osteoarthritis is the most common chronic rheumatic disease. Various factors can be implicated in its appearance, such as age, obesity, genetic factors etc ... Osteoarthritis is usually treated with anti-inflammatory drugs to reduce pain and pain. signs of inflammation.

  Metabolic deficiencies (such as vitamin deficiency) occurring in the pathology are much less often taken into account, although their accumulation contributes to the imbalance of the body and constitutes an additional risk for the evolution of the disease and its symptoms. complications.

  Thus selenium deficiency can lead to the inhibition of collagen type II synthesis by chondrocytes (the cells that generate cartilage). Vitamin C deficiency decreases the inhibition of arylsulfatase, an enzyme that breaks down sulfate bonds in glycosaminoglycans, essential components of cartilage. Similarly zinc, naturally present in healthy chondrocytes and extracellular matrix, is decreased in quantity by 50% in some forms of rheumatic disease. Low levels of vitamin D were inversely correlated with increased severity of osteoarthritis and cartilage loss. A deficiency of vitamin B6 causes a decrease in the concentration of proteoglycans in the cartilage, thus making it more fragile.

  It follows from the above that the accompanying measures of certain diseases are not always sufficient to completely control the pathology and prevent the generation of risk factors for various complications.

  The nutritional deficiencies usually associated with these diseases are very rarely taken into consideration: thus, the vitamins, minerals, trace elements and antioxidants present in a patient are not part of the biological assessments performed for the majority of diseases.

  One of the aims of the present invention is to provide health professionals and patients with natural and pleasant means of filling their nutritional deficits related to their disease, and of optimizing the conditions of their specific treatment.

  Another aim is to prepare a dietary supplement intended to accompany the specific drug treatment of a specific disease, in order to correct the nutritional deficiencies related to this disease, and to reduce the risk of complications and / or progression to complications. possible.

  Yet another object of the invention is to prepare a food supplement acting in synergy with a medicament for treating a specific disease.

  The dietary supplement according to the invention is characterized in that it comprises a pasty matrix based on polymerized carbohydrates giving it a solid or semi-solid gelled consistency, in which are incorporated one or more nutrients and / or ingredients having a nutritional effect. and / or physiological.

  In a preferred manner, the pasty matrix is based on fructooligosaccharides conferring on it a filamentous structure.

  The nutrients and / or ingredients are advantageously chosen from extracts of plant origin, fruits, vegetables, plants, and / or of animal origin, vitamins, macro-elements, and trace elements.

  The extracts used are crude or purified and / or correspond to synthetic products authorized in the human diet.

  Extracts of fruits, vegetables and / or plants include concentrated juices, pulp and dry extracts or powders.

  Examples of fruits that are suitable for the implementation of the invention include the following fruits: tomato, blueberry, blackcurrant, elderberry, orange, lemon, apple 3o, quince, pear, strawberry, cherry, raspberry, fig, prickly pear , peach, banana, pineapple, grape, mango, papaya, kiwi, date, mangosteen, passion fruit, lingonberry, guava, grapefruit, or their mixtures.

  The following vegetables are advantageously used: cabbage, carrot, garlic, onion, broccoli, artichoke, celery, card, mushrooms, spinach, fennel, olive, purslane, soya, or their mixtures.

  Suitable plants include: turmeric, ginger, saffron, nutmeg, thyme, rosemary, cumin, chilli, mint, paprika, sage. Other plant extracts are selected from: angelica, oats, bamboo, banaba, burdock, boswella, chamomile, cordalys, echinacea, ash, garcinia, ginseng, gingko, griffonia, cola, lithotame, neem, mastic, blueberry, olive, nettle, poplar, licorice, pink, scrutinellar, shitake, silgesbeckia, green tea, white tea, black tea, violet, or their mixtures.

  Vitamins are chosen, in particular, in the group comprising vitamin A, vitamin B1, vitamin B2, vitamin B3 (PP), vitamin B5, vitamin B6, vitamin B9, vitamin B12, vitamin C , vitamin D, vitamin E, vitamin K, or their mixtures.

  The minerals are chosen in particular from the group comprising calcium, magnesium, iron, phosphorus, potassium, sodium or their mixtures.

  As micronutrients, mention will be made of those of the group comprising copper, iron, iodine, manganese, selenium, zinc, chromium, molybdenum, fluorine, or mixtures thereof.

  Carbohydrates are advantageously selected from the group consisting of simple monosaccharides (for example glucose, mannose, galactose ribose, fructose), monosaccharides (for example: lactose, sucrose, maltose, glucuronic acid, fucose), polysaccharides. (starches, glycogen, cellulose), glycosides or mixtures thereof.

  The proteins are chosen from the group consisting of amino acids (for example arginine, aspartic acid, glutamine, etc.), amino acid derivatives (for example carnitine, ornithine, hydroxyproline, glutathione, etc.), and the proteins or their mixtures or derivatives.

  The lipids are chosen from the group comprising fats of plant or animal origin, fatty acids (for example palmitic acid, stearic acid, oleic acid, linoleic acid, linolenic acid, arachidonic acid), lipid alcohols (for example glycerol, ethanolamine). serine, choline, inositol), neutral lipids (eg glyceride, diglyceride), complex lipids (e.g. lecithin, phosphatidyl serine, phosphatidyl inositol, sphingolipids, cerebrosides), or mixtures thereof.

  Other active ingredients of interest are selected from L-carnitine, glucosamine, chondroitin sulfate, ubiquinone, or mixtures thereof.

  According to one provision of the invention, the pasty matrix serving as a base for the food supplement of the invention further comprises a moistening agent, or a diluting agent, an emulsifier, stabilizer and / or gelling agent, a sweetening agent, an agent taste developer, a food flavoring agent, a food coloring agent and / or a coating agent.

  As a moistening or dilution agent, it is advantageous to use water, the sweetening agent is, for example, a natural sugar such as glucose, fructose, sucrose, sorbitol, xylitol and / or an artificial sweetening agent, such as as for example aspartame, acesulfame, saccharin or others of the group E 900 to E 1520, or mixtures thereof.

  The following ingredients may be further incorporated into the pasty matrix, for example food flavoring agents, such as fruit flavorings, natural or synthetic, food coloring agents selected for example from the group E100 to E180 and / or coating.

  Other products include preserving agents, chosen for example from the group E200 to E 297, the antioxidants chosen in particular from the group E300 to E 321, the emulsifying agents, stabilizers and / or gelling agents.

  The acidifying or alkalinizing agents are chosen in particular from the group E500 to E585, taste developers selected from the group E600 to E641, and various agents selected from the group E900 to E150.

  Preferred dietary supplements contain from about 10% to 70% by weight of active ingredients, i.e., nutritional and / or physiological effect, based on the total weight of said supplements.

  Food supplement characterized in that the amount of the various constituents of the base formulation varies in particular from 30% to 90% by weight relative to the total weight of said complement.

  Advantageously, the active ingredients present in the food supplement of the invention have not undergone any alteration during the preparation of said supplement.

  Indeed, in accordance with the invention, the pasty matrices of the invention are first prepared by heating constituents used up to a temperature not exceeding about 60 ° C., and the active ingredients are added thereto during the course of the invention. cooling, so that they do not undergo any alteration by heat.

  The food supplements of the present invention may for example be taken in combination with accompanying specific treatments suitable for the following pathologies: cardiovascular diseases, gastrointestinal diseases, neurological diseases, infectious diseases, dermatological diseases, osteoarticular diseases, metabolic diseases, degenerative diseases, etc., but this list is not exhaustive.

  Preferred dietary supplement formulations are in a 10 g portion, chewable, individually packaged. The pleasant taste of the supplements facilitates the good follow-up of their prescription.

  These portions will be advantageously taken outside of meals and outside the taking of drugs.

  The following examples illustrate the invention. They do not limit it in any way.

  Example 1 - Dietary supplement for subjects affected by glucose intolerance syndrome or type 2 diabetes.

  The composition of such a dietary supplement comprises a grape seed extract, a powerful antioxidant, 10-50 g / kg, in particular 30 g / kg. L-carnitine to prevent neuropathy 1- 20 g / kg, in particular 15g / kg Vitamin B12 to prevent neuropathic pain 0.1-0.5 mg / kg, including 0.3 mg / kg Vitamin C to prevent cataract and retinopathy 3-20 g / kg, including 6 g / kg - Vitamin E to prevent retinopathy 0.5-2 g / kg, in particular 1.2 g / kg Magnesium to correct deficits due to diabetes 10-50 g / kg, in particular 30 g / kg Chromium to improve the metabolism of sugar 5-15 mg / kg, especially 12.5 mg / kg zinc to protect the insulin receptor gene from oxidation 0.2-1.5 g / kg, especially 1 , 2 g / kg Omega 3 fatty acids to improve lipid metabolism and protect the vascular system 50-200 g / kg, especially 100 g / kg in a fruit paste composed of: Beet fructo-oligosaccharides, for oven fiber, texture and softness without the secretory action of insulin, and to increase natural immunity through their specific pre-biotic activity, 50-200 g / kg, especially 350 g / kg Fruit of Vaccinium myrtillus rich in anthocyanosides, in the form of concentrated juice, a powerful antioxidant to protect the vascular system and the eyes against oxidation reactions 20-200 g / kg, especially 150 g / kg Gelatin (gelling agent) -30 g / kg, especially 20 g / kg Excipients: aroma, citric acid, color qs Water qs per 100 portions each having a weight of about 10 g.

  The method of administration of the supplement described above is as follows: It may be advisable, for each subject receiving a prescription for a specific treatment of a disease or a diet for the same disease, by a doctor and / or a pharmacist and / or another health professional, to take a daily portion of the dietary supplement as described above, in order to improve his overall balance and well-being, and to reduce the risk of complications of his disease.

  Preferably a portion of the dietary supplement as described above will be taken regularly, outside of mealtimes or drug intake, in order to benefit in the long term the activity of the ingredients gathered in the pasty matrix, easy to chew and melting in the mouth.

  Advantageously, the supplement as described above makes it possible to improve the general equilibrium and the well-being of the subjects affected by a syndrome of glucose intolerance or type 2 diabetes, and makes it possible to reduce the risks of complications related to their disease.

  Example 2 Food Supplement for Subjects Affected by a Degenerative Joint Disease such as Osteoarthritis The composition of such a dietary supplement comprises an extract of Boswella serrata, 10-100 g / kg, in particular 50 g / kg for its anti-inflammatory activity - an extract of Camellia sinensis, 10-100 g / kg, in particular 50 glkg, to prevent cartilage degradation, glucosamine, 10/100 glkg, especially 50 g / kg, to protect the cartilage and reduce inflammation, Chondroitin sulfate, 101100 g / kg, especially 50 g / kg, to protect the cartilage and reduce inflammation B3, B6, B9, B12 vitamins, respectively 0.5-2 mg / kg, especially 1.8 mg / kg, 0.1-0.3 mg / kg, in particular 0.2 mg / kg, 0.01-0.05 mg / kg, in particular 0.03 mg / kg and 0.01- 0.05 mg / kg, in particular 0.3 mg / kg, to contribute to the reduction of inflammation, vitamin C (3-20 g / kg, in particular 6 g / kg) and vitamin E (0 , 5-2 g / kg, in particular 1.2 g / kg) to limit stress oxidative on cartilage and reduce joint pain, vitamin D3 (0.5-2 mg / kg, especially 1.5 mg / kg) to reduce cartilage degradation, manganese (0.1-0.5 g / kg, especially 0.2 g / kg) for optimal glucosamine activity, selenium, 1-7 mg / kg, especially 5 mg / kg, to reduce oxidative stress on the cartilage, zinc, 0, 5-1.5 mg / kg, in particular 1.2 mg / kg, to compensate for the reduced levels found in osteoarthritic cartilage, in a pasty matrix composed of: Beet fructo-oligosaccharides, 100-800 g / kg, in particular 500 g / kg, to provide fiber, texture and softness and to increase natural immunity through its specific pre-biotic activity, tomato concentrate, 50-250 g / kg, especially 100 g / kg, a source of anti-oxidant lycopene, gelatin, 5-30 g / kg, in particular 20 g / kg, gelling agent Excipients: aroma, citric acid, color qs Water qs per 100 portions each having a weight of about 10 g.

  The method of complement administration described above is the same as that described in Example 1. The supplement makes it possible to improve the general balance of the body and the well-being of the subjects affected by osteoarthritis. and reduces the risk of complications related to their disease.

  Example 3 - Dietary supplement for subjects affected by hyperlipidemia (= increase in the level of lipids circulating in the blood) The composition of such a dietary supplement comprises: L-arginine (antiatherogenic, vasodilator) 2-20 g / kg, especially 10 g / kg io - Omega 3 fatty acids (cardiovascular protection) 50-200 g / kg, in particular 100 g / kg Olive tree extract (antioxidant): 10-100 g / kg, in particular 50 g / kg oatmeal (decreases triglycerides) 10-100 g / kg, especially 50g / kg Kola extract (decreases fat absorption): 10-100 g / kg, especially 50g / kg Vitamin B6: (decreases the rate homocysteine: fight against cardiovascular complications): 0,1-0,3 g / kg, in particular 0, 2g / kg Vitamin B9 (decreases the level of homocysteine: fight against the cardiovascular complications): 0 , 01-0.05 g / kg, in particular 0.03 g / kg Vitamin B12 (decreases the level of homocysteine: fight against cardiovascular complications): 0.1-0.5 mg / kg, in particular 0.3 mg / kg Vitamin C (complementary to the action of L-arginine antioxidant): 3-20 g / kg, especially 6g / kg - Vitamin E (decreases the triglyceride level): 0.5-2 g / kg , in particular 1.2 g / kg - magnesium (anti-stress contributes to the fight against the constitution of atheroma plaques) 10-50 g / kg, in particular 30 g / kg in a pasty matrix composed of: beet fructo-oligosaccharides, 100-800 g / kg, especially 450 g / kg, to provide fiber, texture and softness and to increase natural immunity through its specific pre-biotic activity, Kiwi Juice Concentrate, 50-250 g / kg, in particular 100 g / kg, (decreases lipid absorption) 2864426 He Concentrated blueberry juice 50-250 g / kg, especially 100g / kg (decreases lipid absorption) Gelatin, 5-30 g / kg, in particular 20 g / kg, gelling agent Excipients: aroma, citric acid, dye qs - Water qs per 100 portions, each having a weight of approximately 10 g.

  The method of administration of the complement described above is the same as that described in Example 1. The supplement makes it possible to improve the general balance of the body and the well-being of the subjects affected with hyperlipidemia and allows to reduce the risk of complications related to their disease.

  Example 4 Food Supplement for Subjects Affected by a Gastric Disease The composition of such a dietary supplement comprises is a Griffonia extract (re-equilibrium mood, anti-stress) 10 g / kg, in particular 50 g / kg an extract of Aspérule (nervous sedative, antistress) 10-100 g / kg, in particular 50 g / kg an extract of deglycyrrhinisé licorice (anti-ulcer, anti-bleeding) 10-20 100 g / kg, in particular 50 g / kg an extract of Pistacia lentiscus (helps to fight against Helicobacter pylori infections) 10-100 g / kg, in particular 50 g / kg Glutamine (amino acid participating in the health of the gastric mucosa) - Vitamin A (anti-inflammatory effect) 20-100 g / kg, in particular 40 mg / kg Copper (contributes to the repair of the attacked mucosa) 50-300 g / kg, in particular 200 mg / kg - Zinc (contributes to the repair of the attacked mucosa) 0.5-1 , 5 g / kg, in particular 1.2 g / kg in a pasty matrix composed of: beet fructo-oligosaccharides, 100-800 g / kg, in particular 500 g / kg, to provide fiber, texture and softness and to increase natural immunity through its specific pre-biotic activity, angelica concentrate, 50-250 g / kg, especially 100 g / kg. kg, (antiballooning, anti-spasm, stimulates digestion) - Gelatin, 20 g / kg 5-30, gelling agent Excipients: aroma, citric acid, color qs Water qs per 100 portions each having a weight of about 10 g .

  The method of complement administration described above is the same as that described in Example 1. The supplement makes it possible to improve the general balance of the body and the well-being of subjects suffering from a pathology. gastric and reduces the risk of complications related to their disease.

  Example 5 - Dietary Supplement for Subjects Affected by Arterial Hypertension The composition of such a dietary supplement includes: A shark cartilage extract (contributes to lowering blood pressure and parathyroid hormone level) 10-100 g / kg, in particular 50 g / kg An extract of Berce Spondyle (contributes to decrease the HTA and the renal insufficiency), 10-100 g / kg, in particular 50 g / kg Fatty acids Omega 3 (cardiovascular protection) 50 -200 g / kg, in particular 100 g / kg L-arginine (vasodilator amino acid, anti-atherogenic and anti-platelet adhesion) 5-50 g / kg, in particular 20 g / kg Taurine (anti-stress derivative) 5-10 g / kg, especially 20g / kg Ubiquinone (stabilizing membrane antioxidant, increases resistance to exercise and decreases ischemia) 1g / kg, especially 5g / kg - Vitamin B3 (anti-stress) 0.5- 2 g / kg, in particular 1.8 g / kg - Vitamin B6: (decreases the level of homocysteine: fight against cardiovascular complications) 0.1-0.3 glk g, in particular 0.2 g / kg Vitamin B9 (decreases the level of homocysteine: fight against cardiovascular complications) 0.01-0.03 g / kg, in particular 0.03 g / kg Vitamin B12 (decreases the homocysteine level: fight against cardiovascular complications) 0.1-0.5 mg / kg, in particular 0.3 mg / kg 3o Vitamin C (complementary to the action of L-arginine antioxidant): 3-20 g / kg, especially 6 g / kg - Vitamin E (decreases the triglyceride level): 0.5-2 g / kg, in particular 1, 2 g / kg Magnesium (anti-stress contributes to fight against the constitution 10-50 g / kg, in particular 30 g / kg in a pasty matrix composed of: beet fructo-oligosaccharides, 100-800 g / kg, in particular 500 g / kg to provide fibers, texture and softness and to increase natural immunity through its specific pre-biotic activity Concentrated tangerine juice, 50-250 g / kg, especially 100 g / kg coconut pulp 50-250 g / kg, especially 100 g / kg Gelatin, 5-30 g / kg 20 g / kg, gelling agent Excipients: aroma, citric acid, color qs Water qs per 100 portions each having a weight of about 10 g.

  The method of administration of the complement described above is the same as that described in Example 1. The supplement makes it possible to improve the general equilibrium of the organism and the well-being of subjects suffering from a gastric pathology. and reduces the risk of complications related to their disease.

  Example 6 Food Supplement for Subjects Treated with Antibiotic Therapy for a Bacterial Infection The composition of such a dietary supplement comprises: An extract of thyme (anti-mycotic) 10 g / kg, in particular 50 g / kg Sage extract (anti-fungal) -mycotic) 10-100 g / kg, especially 50 g / kg - Shitake extract (natural immunity stimulant) 10-100 g / kg, especially 50 g / kg - Chamomile extract (anti-mycotic) 10-100 g / kg, in particular 50 g / kg A ginger extract (anti-mycotic, anti-oxidant) 10-100 g / kg, in particular 50 g / kg - Vitamin B3 (anti-inflammatory effect) 0.5- 3 g / kg, in particular 1.8 g / kg - Manganese (infection control) 100-600 mg / kg, in particular 30 400 mg / kg Zinc (infection control) 0.5-1.5 g / kg , in particular 1.2 g / kg Copper (infection control) 50-300 g / kg, in particular 200 mg / kg in a pasty matrix composed of: Beet fructo-oligosaccharides, 100-800 g / kg, in particular 500 g / kg, to provide fibers, tex ture and softness without the secretory action of insulin, and to increase natural immunity through its specific pre-biotic activity, Guava concentrated juice, 50-250 g / kg, especially 100 g / kg, (anti- diarrheal, anti-mycotic) Gelatin, 5-30 g / kg, in particular 20 g / kg, gelling agent Excipients: aroma, citric acid, color qs Water qs per 100 portions each having a weight of about 10 g.

  The method of administration of the complement described above is the same as that described in Example 1. The supplement makes it possible to improve the general balance of the body and the well-being of the subjects treated with antibiotics for an infection. bacterial and reduces the risk of complications related to their disease.

Claims (9)

  1- dietary supplement, characterized in that it comprises a pasty matrix based on polymerized carbohydrates conferring a solid or semi-solid gelled consistency, in which are incorporated one or more nutrients and / or ingredients having a nutritional effect and / or physiological.   2- food supplement according to claim 1, characterized in that the pasty matrix is based on fructooligosaccharides conferring a filamentous structure.   3- dietary supplement, according to claim 1 or 2, characterized in that the nutrients and / or ingredients are selected from extracts of plant origin, fruits, vegetables, plants, and / or of animal origin, vitamins, minerals, carbohydrates, proteins, lipids, macro-elements, and / or trace elements.   4- Food supplement according to claim 3, characterized in that the plant or fruit extracts correspond to concentrated juices, pulp and dry extracts or powders.   5- food supplement according to any one of claims 1 to 4, characterized in that the base formulation further comprises a moistening agent or a diluting agent, an emulsifier, stabilizer and / or gelling agent, a sweetening agent, a flavoring agent, a food flavoring agent, a food coloring agent and / or a food additive according to one of claims 1 to 5, characterized in that the amount of active ingredients varies by 10% at 70% by weight relative to the total weight of said complement.   7- food supplement according to one of claims 1 to 6, characterized in that the amount of the various constituents of the base formulation varies from 30% to 90% by weight relative to the total weight of said complement.   8- dietary supplement according to any one of claims 1 to 7, characterized in that it is in portions of 10 grams to be chewed.   9- A process for preparing a food supplement according to any one of claims 1 to 8, characterized in that first prepares the pasty matrix by heating the constituents used, at a temperature not exceeding 60 C then add the ingredients during cooling.   10- Use of the supplements according to any one of claims 1 to 8, in combination with specific treatments of pathologies.