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FR2736358B1 - RECOMBINANT MYXOMATOUS VIRUS - Google Patents

RECOMBINANT MYXOMATOUS VIRUS

Info

Publication number
FR2736358B1
FR2736358B1 FR9508128A FR9508128A FR2736358B1 FR 2736358 B1 FR2736358 B1 FR 2736358B1 FR 9508128 A FR9508128 A FR 9508128A FR 9508128 A FR9508128 A FR 9508128A FR 2736358 B1 FR2736358 B1 FR 2736358B1
Authority
FR
France
Prior art keywords
myxomatous
recombinant
virus
recombinant myxomatous
myxomatous virus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR9508128A
Other languages
French (fr)
Other versions
FR2736358A1 (en
Inventor
Stephane Bertagnoli
Jacqueline Gelfi
Baralon Corine Boucraut
Frederique Petit
Alain Milon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut National de la Recherche Agronomique INRA
Original Assignee
Institut National de la Recherche Agronomique INRA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut National de la Recherche Agronomique INRA filed Critical Institut National de la Recherche Agronomique INRA
Priority to FR9508128A priority Critical patent/FR2736358B1/en
Priority to DE19627193A priority patent/DE19627193B4/en
Priority to IT96TO000578A priority patent/IT1286307B1/en
Priority to ES09601551A priority patent/ES2113322B1/en
Publication of FR2736358A1 publication Critical patent/FR2736358A1/en
Application granted granted Critical
Publication of FR2736358B1 publication Critical patent/FR2736358B1/en
Priority to FR11C0050C priority patent/FR11C0050I2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/125Picornaviridae, e.g. calicivirus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/275Poxviridae, e.g. avipoxvirus
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/542Mucosal route oral/gastrointestinal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/24011Poxviridae
    • C12N2710/24034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/24011Poxviridae
    • C12N2710/24041Use of virus, viral particle or viral elements as a vector
    • C12N2710/24043Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/16011Caliciviridae
    • C12N2770/16034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
FR9508128A 1995-07-05 1995-07-05 RECOMBINANT MYXOMATOUS VIRUS Expired - Lifetime FR2736358B1 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
FR9508128A FR2736358B1 (en) 1995-07-05 1995-07-05 RECOMBINANT MYXOMATOUS VIRUS
DE19627193A DE19627193B4 (en) 1995-07-05 1996-07-05 Recombinant myxomatic virus
IT96TO000578A IT1286307B1 (en) 1995-07-05 1996-07-05 RECOMBINANT MYXOMATOUS VIRUS, ITS USE FOR THE PRODUCTION OF A VACCINE AND RELATED VACCINE.
ES09601551A ES2113322B1 (en) 1995-07-05 1996-07-05 RECOMBINANT MIXOMATOUS VIRUSES.
FR11C0050C FR11C0050I2 (en) 1995-07-05 2011-11-15 RECOMBINANT MYXOMATOUS VIRUS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9508128A FR2736358B1 (en) 1995-07-05 1995-07-05 RECOMBINANT MYXOMATOUS VIRUS

Publications (2)

Publication Number Publication Date
FR2736358A1 FR2736358A1 (en) 1997-01-10
FR2736358B1 true FR2736358B1 (en) 1997-09-26

Family

ID=9480712

Family Applications (2)

Application Number Title Priority Date Filing Date
FR9508128A Expired - Lifetime FR2736358B1 (en) 1995-07-05 1995-07-05 RECOMBINANT MYXOMATOUS VIRUS
FR11C0050C Active FR11C0050I2 (en) 1995-07-05 2011-11-15 RECOMBINANT MYXOMATOUS VIRUS

Family Applications After (1)

Application Number Title Priority Date Filing Date
FR11C0050C Active FR11C0050I2 (en) 1995-07-05 2011-11-15 RECOMBINANT MYXOMATOUS VIRUS

Country Status (4)

Country Link
DE (1) DE19627193B4 (en)
ES (1) ES2113322B1 (en)
FR (2) FR2736358B1 (en)
IT (1) IT1286307B1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2153284B1 (en) * 1998-06-10 2001-09-01 Fundacion Para El Estudio Y De NEW RECOMBINANT VIRUS OF ATTENATED MIXOMA AND ITS USE IN THE PREPARATION OF MIXED VACCINES AGAINST MIXOMATOSIS AND HEMORRAGICAL DISEASE OF THE RABBITS.
DK1370668T3 (en) 2001-03-08 2006-06-06 Akzo Nobel Nv Leporipox-based vector vaccines
FR2946536B1 (en) * 2009-06-11 2011-07-29 Agronomique Inst Nat Rech USE OF AN ATXURATED STRAIN OF MYXOMA VIRUS AS AN ONCOLYTIC
WO2017037523A1 (en) 2015-06-19 2017-03-09 Sillajen, Inc. Compositions and methods for viral embolization

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5869312A (en) * 1992-01-13 1999-02-09 Syntro Corporation Recombinant swinepox virus

Also Published As

Publication number Publication date
FR11C0050I1 (en) 2011-12-16
DE19627193A1 (en) 1997-03-20
FR11C0050I2 (en) 2012-06-22
ITTO960578A0 (en) 1996-07-05
ES2113322A1 (en) 1998-04-16
DE19627193B4 (en) 2007-08-30
IT1286307B1 (en) 1998-07-08
ITTO960578A1 (en) 1998-01-05
ES2113322B1 (en) 1998-12-01
FR2736358A1 (en) 1997-01-10

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Legal Events

Date Code Title Description
CP Supplementary protection certificate (spc) filed

Free format text: PRODUCT NAME: VIRUS VIVANT DE LA MYXOMATOSE EXPRIMANT UNE GLYCOPROTEINE DU VIRUS DE LA MHL, SOUCHE 009; REGISTRATION NO/DATE: EU/2/11/132/001-004 20110907

Spc suppl protection certif: 11C0050

Filing date: 20111115

CP Supplementary protection certificate (spc) filed

Free format text: PRODUCT NAME: NOBIVAC MYXO-RHD VIRUS VIVANT DE LA MYXOMATOSE EXPRIMANT UNE GLYCOPROTEINE DU VIRUS DE LA MHL, SOUCHE 009; REGISTRATION NO/DATE: EU/2/11/132/001-004 20110907

Spc suppl protection certif: 11C0050

Filing date: 20111115

CP Supplementary protection certificate (spc) filed

Effective date: 20111130

CT Granted supplementary protection certificate (spc) for medicine (eec regulation of 18 june 1992)

Free format text: PRODUCT NAME: VIRUS VIVANT DE LA MYXOMATOSE EXPRIMANT UNE GLYCOPROTEINE DU VIRUS DE LA MHL, SOUCHE 009; REGISTRATION NO/DATE: EU/2/11/132/001-004 20110907

Spc suppl protection certif: 11C0050

Filing date: 20111115

Extension date: 20200704

Effective date: 20120622

AV Other action affecting the existence or the validity of an industrial property right

Effective date: 20120524

CT Granted supplementary protection certificate (spc) for medicine (eec regulation of 18 june 1992)

Free format text: PRODUCT NAME: VIRUS VIVANT DE LA MYXOMATOSE EXPRIMANT UNE GLYCOPROTEINE DU VIRUS DE LA MHL, SOUCHE 009; REGISTRATION NO/DATE: EU/2/11/132/001 20110907

Spc suppl protection certif: 11C0050

Filing date: 20111115

Extension date: 20200704

SPAY Annual fee for spc paid [supplementary protection certificate]

Free format text: PRODUCT NAME: VIRUS VIVANT DE LA MYXOMATOSE EXPRIMANT UNE GLYCOPROTEINE DU VIRUS DE LA MHL, SOUCHE 009; REGISTRATION NO/DATE: EU/2/11/132/001-004 20110907

Spc suppl protection certif: 11C0050

Filing date: 20111115

Year of fee payment: 1

Extension date: 20200704

SPAY Annual fee for spc paid [supplementary protection certificate]

Free format text: PRODUCT NAME: VIRUS VIVANT DE LA MYXOMATOSE EXPRIMANT UNE GLYCOPROTEINE DU VIRUS DE LA MHL, SOUCHE 009; REGISTRATION NO/DATE: EU/2/11/132/001-004 20110907

Spc suppl protection certif: 11C0050

Filing date: 20111115

Year of fee payment: 2

Extension date: 20200704

SPAY Annual fee for spc paid [supplementary protection certificate]

Free format text: PRODUCT NAME: VIRUS VIVANT DE LA MYXOMATOSE EXPRIMANT UNE GLYCOPROTEINE DU VIRUS DE LA MHL, SOUCHE 009; REGISTRATION NO/DATE: EU/2/11/132/001-004 20110907

Spc suppl protection certif: 11C0050

Filing date: 20111115

Year of fee payment: 3

Extension date: 20200704

SPAY Annual fee for spc paid [supplementary protection certificate]

Free format text: PRODUCT NAME: VIRUS VIVANT DE LA MYXOMATOSE EXPRIMANT UNE GLYCOPROTEINE DU VIRUS DE LA MHL, SOUCHE 009; REGISTRATION NO/DATE: EU/2/11/132/001-004 20110907

Spc suppl protection certif: 11C0050

Filing date: 20111115

Year of fee payment: 4

Extension date: 20200704

SPAY Annual fee for spc paid [supplementary protection certificate]

Free format text: PRODUCT NAME: VIRUS VIVANT DE LA MYXOMATOSE EXPRIMANT UNE GLYCOPROTEINE DU VIRUS DE LA MHL, SOUCHE 009; REGISTRATION NO/DATE: EU/2/11/132/001-004 20110907

Spc suppl protection certif: 11C0050

Filing date: 20111115

Year of fee payment: 5

Extension date: 20200704