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FR2755133B1 - Nouveaux derives d'amides cycliques diversement substitues antagonistes selectifs du recepteur nk3 humain, procede pour leur obtention et compositions pharmaceutiques les contenant - Google Patents

Nouveaux derives d'amides cycliques diversement substitues antagonistes selectifs du recepteur nk3 humain, procede pour leur obtention et compositions pharmaceutiques les contenant

Info

Publication number
FR2755133B1
FR2755133B1 FR9613313A FR9613313A FR2755133B1 FR 2755133 B1 FR2755133 B1 FR 2755133B1 FR 9613313 A FR9613313 A FR 9613313A FR 9613313 A FR9613313 A FR 9613313A FR 2755133 B1 FR2755133 B1 FR 2755133B1
Authority
FR
France
Prior art keywords
receptor
human
production
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9613313A
Other languages
English (en)
Other versions
FR2755133A1 (fr
Inventor
Nathalie Chabert
Alt Xavier Emonds
Jean Philippe Ducoux
Didier Van Broeck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SA filed Critical Sanofi SA
Priority to FR9613313A priority Critical patent/FR2755133B1/fr
Priority to PCT/FR1997/001954 priority patent/WO1998018762A1/fr
Priority to AU49537/97A priority patent/AU4953797A/en
Publication of FR2755133A1 publication Critical patent/FR2755133A1/fr
Application granted granted Critical
Publication of FR2755133B1 publication Critical patent/FR2755133B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74—Oxygen atoms
    • C07D211/76—Oxygen atoms attached in position 2 or 6

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR9613313A 1996-10-31 1996-10-31 Nouveaux derives d'amides cycliques diversement substitues antagonistes selectifs du recepteur nk3 humain, procede pour leur obtention et compositions pharmaceutiques les contenant Expired - Fee Related FR2755133B1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
FR9613313A FR2755133B1 (fr) 1996-10-31 1996-10-31 Nouveaux derives d'amides cycliques diversement substitues antagonistes selectifs du recepteur nk3 humain, procede pour leur obtention et compositions pharmaceutiques les contenant
PCT/FR1997/001954 WO1998018762A1 (fr) 1996-10-31 1997-10-31 Nouveaux derives d'amides cycliques diversement substitues antagonistes selectifs du recepteur nk3 humain, procede pour leur obtention et compositions pharmaceutiques les contenant
AU49537/97A AU4953797A (en) 1996-10-31 1997-10-31 New derivatives of diversely substituted cyclical amide selective antagonists of the human receptor nk3, process for obtaining them, and pharmaceutical compositions containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9613313A FR2755133B1 (fr) 1996-10-31 1996-10-31 Nouveaux derives d'amides cycliques diversement substitues antagonistes selectifs du recepteur nk3 humain, procede pour leur obtention et compositions pharmaceutiques les contenant

Publications (2)

Publication Number Publication Date
FR2755133A1 FR2755133A1 (fr) 1998-04-30
FR2755133B1 true FR2755133B1 (fr) 1999-01-15

Family

ID=9497226

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9613313A Expired - Fee Related FR2755133B1 (fr) 1996-10-31 1996-10-31 Nouveaux derives d'amides cycliques diversement substitues antagonistes selectifs du recepteur nk3 humain, procede pour leur obtention et compositions pharmaceutiques les contenant

Country Status (3)

Country Link
AU (1) AU4953797A (fr)
FR (1) FR2755133B1 (fr)
WO (1) WO1998018762A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0506800D0 (en) * 2005-04-04 2005-05-11 Merck Sharp & Dohme New uses
ATE517106T1 (de) * 2006-02-22 2011-08-15 Vertex Pharma Kondensierte spiropiperidine als modulatoren muskarinartiger rezeptoren

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2676055B1 (fr) * 1991-05-03 1993-09-03 Sanofi Elf Composes polycycliques amines et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
US5434158A (en) * 1994-04-26 1995-07-18 Merck & Co., Inc. Spiro-substituted azacycles as neurokinin-3 antagonists
ES2132709T3 (es) * 1994-08-25 1999-08-16 Merrell Pharma Inc Nuevas piperidinas substituidas utiles para el tratamiento de las enfermedades alergicas.
FR2729951B1 (fr) * 1995-01-30 1997-04-18 Sanofi Sa Nouveaux composes heterocycliques, procede pour leur preparation et compositions pharmaceutiques en contenant

Also Published As

Publication number Publication date
FR2755133A1 (fr) 1998-04-30
AU4953797A (en) 1998-05-22
WO1998018762A1 (fr) 1998-05-07

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Legal Events

Date Code Title Description
ST Notification of lapse